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Thermo Fisher Scientific Inc. (NYSE:TMO)

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DuPont Analysis: Disaggregation of ROE, ROA, and Net Profit Margin
Quarterly Data

Microsoft Excel

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Two-Component Disaggregation of ROE

Thermo Fisher Scientific Inc., decomposition of ROE (quarterly data)

Microsoft Excel
ROE = ROA × Financial Leverage
Dec 31, 2025 = ×
Sep 27, 2025 = ×
Jun 28, 2025 = ×
Mar 29, 2025 = ×
Dec 31, 2024 = ×
Sep 28, 2024 = ×
Jun 29, 2024 = ×
Mar 30, 2024 = ×
Dec 31, 2023 = ×
Sep 30, 2023 = ×
Jul 1, 2023 = ×
Apr 1, 2023 = ×
Dec 31, 2022 = ×
Oct 1, 2022 = ×
Jul 2, 2022 = ×
Apr 2, 2022 = ×

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).


The analysis reveals a consistent pattern of declining profitability as measured by Return on Equity (ROE) over the observed period, though with some stabilization in more recent quarters. This decline is attributable to both decreasing Return on Assets (ROA) and a reduction in Financial Leverage, though the impact of ROA’s decline appears more significant.

Return on Equity (ROE)
ROE experienced a notable decrease from 18.56% in April 2022 to 12.55% in December 2025. The most substantial declines occurred between April 2022 and December 2022, and again between December 2022 and December 2023. A slight recovery is observed in the most recent quarters, with ROE reaching 13.19% in March 2025 and 13.03% in June 2025 before a minor decrease to 12.88% in September 2025. The final reported value is 12.55%.
Return on Assets (ROA)
ROA generally trended downward from 8.20% in April 2022 to 6.08% in December 2025. Similar to ROE, the largest decrease in ROA occurred in the period between April 2022 and December 2022. There is some fluctuation in ROA, with a peak of 6.36% in April 2023, but the overall trend remains negative. The most recent quarters show a slight stabilization, but remain below the initial values.
Financial Leverage
Financial Leverage exhibited a decreasing trend, starting at 2.26 in April 2022 and falling to 2.07 in December 2025. The decline was most pronounced between April 2022 and October 2022. While the decrease in leverage contributes to the decline in ROE, its impact is less substantial than that of the decreasing ROA. The rate of decline in leverage slowed considerably after July 2023, indicating a potential stabilization of the company’s capital structure.

The interplay between ROA and Financial Leverage suggests that the primary driver of the observed ROE decline is a reduction in the company’s ability to generate earnings from its assets. While the company has reduced its reliance on financial leverage, this has not been sufficient to offset the impact of lower asset profitability. The recent stabilization in both ROA and leverage suggests a potential leveling off of the ROE decline, but further monitoring is warranted to confirm this trend.


Three-Component Disaggregation of ROE

Thermo Fisher Scientific Inc., decomposition of ROE (quarterly data)

Microsoft Excel
ROE = Net Profit Margin × Asset Turnover × Financial Leverage
Dec 31, 2025 = × ×
Sep 27, 2025 = × ×
Jun 28, 2025 = × ×
Mar 29, 2025 = × ×
Dec 31, 2024 = × ×
Sep 28, 2024 = × ×
Jun 29, 2024 = × ×
Mar 30, 2024 = × ×
Dec 31, 2023 = × ×
Sep 30, 2023 = × ×
Jul 1, 2023 = × ×
Apr 1, 2023 = × ×
Dec 31, 2022 = × ×
Oct 1, 2022 = × ×
Jul 2, 2022 = × ×
Apr 2, 2022 = × ×

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).


The three-component DuPont analysis reveals a generally declining trend in Return on Equity (ROE) over the observed period, though with some stabilization and slight increases in more recent quarters. This decline appears to be driven by a combination of factors affecting Net Profit Margin, Asset Turnover, and Financial Leverage, with varying degrees of influence throughout the timeframe.

Net Profit Margin
The Net Profit Margin demonstrated a consistent decrease from 18.49% in April 2022 to a low of 13.14% in July 2023. Subsequently, the margin experienced a recovery, rising to 15.23% by June 2025. While fluctuations occurred, the most recent values indicate a return towards the higher end of the observed range, suggesting improved profitability in recent periods. The initial decline may indicate increased costs or pricing pressures, while the later recovery suggests successful mitigation strategies.
Asset Turnover
Asset Turnover exhibited a modest increase from 0.44 in April 2022 to 0.49 in October 2022, followed by a gradual decline to 0.40 by December 2025. This suggests a decreasing efficiency in utilizing assets to generate revenue. The initial improvement could be attributed to increased sales volume relative to asset base, while the subsequent decline indicates a potential slowdown in sales or an increase in asset investment without a corresponding increase in revenue. The trend is relatively stable, but the overall direction is downward.
Financial Leverage
Financial Leverage generally decreased from 2.26 in April 2022 to a low of 1.96 in December 2024, before stabilizing and slightly increasing to 2.07 by December 2025. This indicates a reduction in the company’s reliance on debt financing. The initial decrease suggests a more conservative capital structure, potentially reducing financial risk, while the recent stabilization and slight increase may reflect a strategic decision to moderately increase leverage. The impact on ROE is positive when leverage is higher, but also increases financial risk.

The interplay between these three components explains the ROE trend. The initial decline in ROE from April 2022 to July 2023 was primarily driven by the decreasing Net Profit Margin, despite a temporary increase in Asset Turnover. The subsequent stabilization and slight recovery in ROE, particularly from June 2024 onwards, are attributable to the rebound in Net Profit Margin, partially offset by the continuing decline in Asset Turnover. Financial Leverage’s influence on ROE has been relatively consistent, with a slight moderating effect due to its overall downward trend.

In conclusion, the analysis suggests that profitability is a key driver of ROE for this entity. While asset utilization has decreased, improvements in net profit margin have helped to mitigate the negative impact on overall returns. Monitoring these trends closely will be crucial for assessing future performance and identifying areas for improvement.


Five-Component Disaggregation of ROE

Thermo Fisher Scientific Inc., decomposition of ROE (quarterly data)

Microsoft Excel
ROE = Tax Burden × Interest Burden × EBIT Margin × Asset Turnover × Financial Leverage
Dec 31, 2025 = × × × ×
Sep 27, 2025 = × × × ×
Jun 28, 2025 = × × × ×
Mar 29, 2025 = × × × ×
Dec 31, 2024 = × × × ×
Sep 28, 2024 = × × × ×
Jun 29, 2024 = × × × ×
Mar 30, 2024 = × × × ×
Dec 31, 2023 = × × × ×
Sep 30, 2023 = × × × ×
Jul 1, 2023 = × × × ×
Apr 1, 2023 = × × × ×
Dec 31, 2022 = × × × ×
Oct 1, 2022 = × × × ×
Jul 2, 2022 = × × × ×
Apr 2, 2022 = × × × ×

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).


The five-component DuPont analysis reveals a generally declining trend in Return on Equity (ROE) over the observed period, although some stabilization and slight increases are noted in more recent quarters. This decline is attributable to a combination of factors impacting profitability, efficiency, and financial leverage. The analysis details these components below.

Tax Burden
The tax burden demonstrates relative stability, fluctuating between 0.88 and 0.95. An increasing trend is observed from 0.88 in Apr 2, 2022, to 0.95 in Jul 1, 2023, followed by a slight decrease to 0.92 in Dec 31, 2025. These fluctuations are relatively minor and do not appear to be a primary driver of the overall ROE trend.
Interest Burden
The interest burden exhibits a consistent downward trend from 0.94 in Apr 2, 2022, to 0.84 in Dec 31, 2025. This suggests a decreasing proportion of operating income is used to cover interest expenses, which positively contributes to ROE. The decline is most pronounced in the earlier part of the period, with a more gradual decrease observed in later quarters.
EBIT Margin
The EBIT margin shows a notable decline from 22.24% in Apr 2, 2022, to 16.81% in Apr 1, 2023. While a modest recovery is seen in subsequent quarters, peaking at 19.56% in Jun 29, 2024, the margin remains below the initial level. The most recent value, 19.46% in Dec 31, 2024, indicates a slight decrease from the peak, but remains relatively stable. This decreasing profitability is a significant contributor to the overall ROE decline.
Asset Turnover
Asset turnover demonstrates a fluctuating pattern. It initially increases from 0.44 in Apr 2, 2022, to 0.49 in Oct 1, 2022, before declining to 0.40 in Dec 31, 2025. This indicates a decreasing efficiency in utilizing assets to generate revenue. The decline in asset turnover negatively impacts ROE, suggesting the company is becoming less effective at converting investments in assets into sales.
Financial Leverage
Financial leverage generally decreases over the period, moving from 2.26 in Apr 2, 2022, to 1.96 in Dec 31, 2024, before increasing slightly to 2.07 in Dec 31, 2025. This suggests a reduction in the use of debt financing relative to equity. While increased leverage can amplify ROE, the observed decrease, coupled with declining profitability and efficiency, contributes to the overall ROE decline. The recent slight increase in leverage does not fully offset the earlier reductions.

In summary, the decline in ROE is primarily driven by decreasing EBIT margin and asset turnover, partially offset by a decreasing interest burden. The reduction in financial leverage also contributes to the downward trend, although to a lesser extent. Recent quarters show some signs of stabilization in the EBIT margin and a slight increase in leverage, but the asset turnover continues to decline, suggesting ongoing challenges in operational efficiency.


Two-Component Disaggregation of ROA

Thermo Fisher Scientific Inc., decomposition of ROA (quarterly data)

Microsoft Excel
ROA = Net Profit Margin × Asset Turnover
Dec 31, 2025 = ×
Sep 27, 2025 = ×
Jun 28, 2025 = ×
Mar 29, 2025 = ×
Dec 31, 2024 = ×
Sep 28, 2024 = ×
Jun 29, 2024 = ×
Mar 30, 2024 = ×
Dec 31, 2023 = ×
Sep 30, 2023 = ×
Jul 1, 2023 = ×
Apr 1, 2023 = ×
Dec 31, 2022 = ×
Oct 1, 2022 = ×
Jul 2, 2022 = ×
Apr 2, 2022 = ×

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).


The financial performance, as indicated by the two-component disaggregation of Return on Assets (ROA), reveals a complex pattern over the observed period. Initially, ROA demonstrated relative stability before experiencing a decline, followed by a period of fluctuation and a subsequent downward trend towards the end of the analyzed timeframe.

Net Profit Margin
The Net Profit Margin exhibited a decreasing trend from 18.49% in April 2022 to a low of 13.14% in July 2023. A subsequent recovery was observed, peaking at 15.23% in June 2025, before settling at 15.05% in December 2025. This suggests improving profitability in the latter part of the period after an initial decline. The most recent values indicate a stabilization around the 15% mark.
Asset Turnover
Asset Turnover showed an initial increase from 0.44 in April 2022 to 0.49 in October 2022, indicating improved efficiency in utilizing assets to generate sales. However, a consistent downward trend followed, decreasing to 0.40 in December 2025. This suggests a diminishing ability to generate sales from the asset base over time. The decline in asset turnover appears to be the primary driver of the overall ROA trend.
Return on Assets (ROA)
ROA began at 8.20% in April 2022 and generally decreased to 6.08% by December 2025. The initial decline was relatively steep, from 8.20% to 7.15% by December 2022. While there were minor fluctuations, the overall trajectory is downward. The interplay between the Net Profit Margin and Asset Turnover is evident; the initial ROA stability was supported by both components, but the subsequent decline in Asset Turnover, despite some recovery in Net Profit Margin, ultimately led to a lower ROA. The most recent ROA value represents a notable decrease from the initial period.

The observed trends suggest that while profitability has shown some resilience and even improvement in recent quarters, the decreasing efficiency in asset utilization is a significant concern. Further investigation into the factors driving the decline in Asset Turnover is warranted to understand the underlying causes and potential mitigation strategies.


Four-Component Disaggregation of ROA

Thermo Fisher Scientific Inc., decomposition of ROA (quarterly data)

Microsoft Excel
ROA = Tax Burden × Interest Burden × EBIT Margin × Asset Turnover
Dec 31, 2025 = × × ×
Sep 27, 2025 = × × ×
Jun 28, 2025 = × × ×
Mar 29, 2025 = × × ×
Dec 31, 2024 = × × ×
Sep 28, 2024 = × × ×
Jun 29, 2024 = × × ×
Mar 30, 2024 = × × ×
Dec 31, 2023 = × × ×
Sep 30, 2023 = × × ×
Jul 1, 2023 = × × ×
Apr 1, 2023 = × × ×
Dec 31, 2022 = × × ×
Oct 1, 2022 = × × ×
Jul 2, 2022 = × × ×
Apr 2, 2022 = × × ×

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).


The financial performance, as disaggregated through a four-component DuPont analysis, reveals several noteworthy trends over the observed period. Return on Assets (ROA) experienced a general decline from 8.20% in April 2022 to 6.08% in December 2025, although with some fluctuations. This overall decrease warrants further investigation into the underlying drivers. The analysis of the components – Tax Burden, Interest Burden, EBIT Margin, and Asset Turnover – provides insights into these fluctuations.

Tax Burden
The Tax Burden remained relatively stable for the majority of the period, fluctuating between 0.88 and 0.95. A slight increase is observed from 0.91 in December 2022 to 0.94 in June 2025, before decreasing slightly to 0.92 in September 2025 and remaining at that level through December 2025. This indicates a consistent, though minor, impact of taxes on overall profitability.
Interest Burden
A consistent downward trend is evident in the Interest Burden, decreasing from 0.94 in April 2022 to 0.84 by December 2025. This suggests improved management of interest-bearing liabilities or a shift in capital structure towards less debt financing, positively impacting profitability. The decline is gradual, indicating a consistent effort in this area.
EBIT Margin
The EBIT Margin demonstrated a clear declining trend from 22.24% in April 2022 to 16.81% in April 2023. It then showed some recovery, peaking at 19.56% in June 2024, before settling at 19.46% in December 2025. This suggests initial pressure on operational profitability, followed by some stabilization and improvement, though not returning to the levels seen in early 2022. The fluctuations may be attributable to changes in cost structures or pricing strategies.
Asset Turnover
Asset Turnover exhibited a moderate increase from 0.44 in April 2022 to 0.49 in October 2022, followed by a gradual decline to 0.40 in December 2025. This indicates a decreasing efficiency in utilizing assets to generate revenue. The decline in asset turnover appears to be the most significant contributor to the overall decrease in ROA, as it consistently offsets the positive impact of the decreasing Interest Burden.

The interplay between these components reveals that while improvements in managing interest expenses were observed, the declining EBIT Margin and, more significantly, the decreasing Asset Turnover, exerted downward pressure on ROA. The stabilization of the Tax Burden had a limited effect on mitigating this overall trend. Further investigation into the factors driving the decline in asset utilization is recommended to understand the underlying causes and potential strategies for improvement.


Disaggregation of Net Profit Margin

Thermo Fisher Scientific Inc., decomposition of net profit margin ratio (quarterly data)

Microsoft Excel
Net Profit Margin = Tax Burden × Interest Burden × EBIT Margin
Dec 31, 2025 = × ×
Sep 27, 2025 = × ×
Jun 28, 2025 = × ×
Mar 29, 2025 = × ×
Dec 31, 2024 = × ×
Sep 28, 2024 = × ×
Jun 29, 2024 = × ×
Mar 30, 2024 = × ×
Dec 31, 2023 = × ×
Sep 30, 2023 = × ×
Jul 1, 2023 = × ×
Apr 1, 2023 = × ×
Dec 31, 2022 = × ×
Oct 1, 2022 = × ×
Jul 2, 2022 = × ×
Apr 2, 2022 = × ×

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).


The information presents a quarterly view of key profitability ratios, specifically focusing on the components impacting net profit margin. A general trend indicates a decline in profitability metrics from early 2022 through the first half of 2023, followed by a period of stabilization and modest improvement through the end of 2025.

Net Profit Margin
Net profit margin experienced a consistent decrease from 18.49% in April 2022 to a low of 13.14% in July 2023. Subsequently, the margin demonstrated a recovery, reaching 15.05% by December 2025. While fluctuations occurred, the overall trend from mid-2023 to the end of the observed period is upward, though the rate of increase appears to be slowing. The most significant decline occurred between April 2022 and July 2023, representing a 5.35 percentage point reduction.
EBIT Margin
The EBIT margin mirrored the trend observed in net profit margin, declining from 22.24% in April 2022 to 16.29% in July 2023. Similar to the net profit margin, the EBIT margin then began to recover, reaching 19.46% by December 2025. The recovery in EBIT margin was more pronounced than the recovery in net profit margin, suggesting that factors beyond EBIT are also influencing overall profitability. The largest decrease in EBIT margin also occurred between April 2022 and July 2023, with a decrease of 5.95 percentage points.
Tax Burden
The tax burden generally increased from 0.88 in April 2022 to 0.95 in September 2023, before stabilizing around 0.92-0.94 for the remainder of the period. This indicates a higher proportion of earnings are being allocated to taxes, contributing to the lower net profit margin, particularly in the earlier part of the observed timeframe. The increase in tax burden between April 2022 and September 2023 is a notable factor in the overall decline in net profit margin.
Interest Burden
The interest burden exhibited a consistent decline from 0.94 in April 2022 to 0.82 in December 2023, and remained relatively stable at 0.83-0.84 through December 2025. This suggests a decreasing impact from interest expenses on profitability. The reduction in interest burden partially offset the negative impact of the increasing tax burden, but was not sufficient to fully counteract the decline in EBIT margin during the initial period.

The interplay between the EBIT margin, tax burden, and interest burden demonstrates how these components collectively influence net profit margin. The initial decline in net profit margin was primarily driven by a decrease in EBIT margin, exacerbated by a rising tax burden. The subsequent recovery in net profit margin was supported by both an increase in EBIT margin and a stabilization of the tax burden, alongside a decreasing interest burden.