Stock Analysis on Net

Eli Lilly & Co. (NYSE:LLY)

DuPont Analysis: Disaggregation of ROE, ROA, and Net Profit Margin 
Quarterly Data

Microsoft Excel

Two-Component Disaggregation of ROE

Eli Lilly & Co., decomposition of ROE (quarterly data)

Microsoft Excel
ROE = ROA × Financial Leverage
Sep 30, 2025 77.38% = 16.02% × 4.83
Jun 30, 2025 75.52% = 13.67% × 5.52
Mar 31, 2025 70.45% = 12.42% × 5.67
Dec 31, 2024 74.62% = 13.45% × 5.55
Sep 30, 2024 58.78% = 11.07% × 5.31
Jun 30, 2024 54.14% = 10.22% × 5.30
Mar 31, 2024 47.91% = 9.60% × 4.99
Dec 31, 2023 48.65% = 8.19% × 5.94
Sep 30, 2023 44.46% = 8.61% × 5.16
Jun 30, 2023 58.73% = 11.85% × 4.95
Mar 31, 2023 50.82% = 10.70% × 4.75
Dec 31, 2022 58.64% = 12.62% × 4.65
Sep 30, 2022 59.91% = 12.71% × 4.71
Jun 30, 2022 66.61% = 12.09% × 5.51
Mar 31, 2022 65.69% = 13.06% × 5.03
Dec 31, 2021 62.16% = 11.44% × 5.44
Sep 30, 2021 76.99% = 12.39% × 6.21
Jun 30, 2021 94.20% = 12.70% × 7.42
Mar 31, 2021 88.31% = 13.01% × 6.79

Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).


Return on Assets (ROA)
The return on assets showed a generally fluctuating pattern over the observed periods. Initially, it started around 13%, then experienced a gradual decline through the end of 2021, reaching a low point near 11.44%. In 2022, the ROA was relatively stable, fluctuating slightly around 12%, but declined noticeably in 2023, dropping to as low as 8.19% by the end of that year. However, from 2024 onward, ROA demonstrated a strong recovery trend, increasing steadily and reaching a peak of 16.02% in the third quarter of 2025. This suggests an improvement in asset utilization and profitability in the latter periods.
Financial Leverage
Financial leverage exhibited a declining trend from early 2021 through the end of 2021, reducing from approximately 6.79 to 5.44. Throughout 2022 and into early 2023, leverage fluctuated within a narrower range, mostly between 4.65 and 5.94, indicating a more stable capital structure. From mid-2023 until the third quarter of 2025, financial leverage remained relatively consistent, generally maintaining levels between 4.8 and 5.7, with a minor decline toward the end of the observed period. This pattern suggests a moderate and stable reliance on debt financing during the later years.
Return on Equity (ROE)
Return on equity demonstrated a significant downward trend from the first quarter of 2021, starting at an elevated level of over 88%, and falling sharply to nearly 44% by the third quarter of 2023. This decline was characterized by some fluctuations but revealed a notable decrease in overall equity profitability. Beginning in 2024, ROE showed a robust recovery, climbing steadily and reaching levels above 77% by mid-2025. The recovery aligns with the improvement observed in ROA, indicating enhanced profitability that benefits shareholder returns despite the relatively stable leverage.

Three-Component Disaggregation of ROE

Eli Lilly & Co., decomposition of ROE (quarterly data)

Microsoft Excel
ROE = Net Profit Margin × Asset Turnover × Financial Leverage
Sep 30, 2025 77.38% = 30.99% × 0.52 × 4.83
Jun 30, 2025 75.52% = 25.91% × 0.53 × 5.52
Mar 31, 2025 70.45% = 22.66% × 0.55 × 5.67
Dec 31, 2024 74.62% = 23.51% × 0.57 × 5.55
Sep 30, 2024 58.78% = 20.48% × 0.54 × 5.31
Jun 30, 2024 54.14% = 18.86% × 0.54 × 5.30
Mar 31, 2024 47.91% = 17.08% × 0.56 × 4.99
Dec 31, 2023 48.65% = 15.36% × 0.53 × 5.94
Sep 30, 2023 44.46% = 15.55% × 0.55 × 5.16
Jun 30, 2023 58.73% = 22.01% × 0.54 × 4.95
Mar 31, 2023 50.82% = 20.54% × 0.52 × 4.75
Dec 31, 2022 58.64% = 21.88% × 0.58 × 4.65
Sep 30, 2022 59.91% = 20.63% × 0.62 × 4.71
Jun 30, 2022 66.61% = 19.58% × 0.62 × 5.51
Mar 31, 2022 65.69% = 20.90% × 0.62 × 5.03
Dec 31, 2021 62.16% = 19.71% × 0.58 × 5.44
Sep 30, 2021 76.99% = 21.52% × 0.58 × 6.21
Jun 30, 2021 94.20% = 22.71% × 0.56 × 7.42
Mar 31, 2021 88.31% = 23.91% × 0.54 × 6.79

Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).


Net Profit Margin
The net profit margin displayed a declining trend from 23.91% at the beginning of the observed period to a low point around the fourth quarter of 2023 with figures near 15.36%. Subsequently, it began a recovery phase, gradually increasing to reach 30.99% by the third quarter of 2025. This pattern indicates an initial decrease in profitability efficiency followed by a significant improvement over the latter periods.
Asset Turnover
Asset turnover remained relatively stable throughout the periods, fluctuating marginally between 0.52 and 0.62. Notably, there was a slight decline in the early 2023 quarters, followed by minor increases and decreases, stabilizing near 0.52 towards the latest periods. Overall, the company's efficiency in utilizing its assets to generate sales maintained a consistent level without major volatility.
Financial Leverage
Financial leverage showed a downward trend from an initial 6.79 ratio, declining steadily to approximately 4.65 by the end of 2022. Thereafter, the leverage ratio fluctuated between roughly 4.83 and 5.94, indicating moderate variability but generally lower leverage compared to the early period. This suggests a reduction in reliance on debt or borrowed funds relative to equity over time, with a slight increase in leverage observed in the mid to later periods.
Return on Equity (ROE)
Return on equity exhibited a pronounced decrease from an exceptionally high 88.31% in early 2021 down to about 44.46% in the third quarter of 2023. Following this trough, ROE gradually rose, reaching 77.38% by the third quarter of 2025. The trend indicates that the company experienced a significant drop in shareholder returns before initiating a recovery, suggesting improvements in profitability, efficiency, or capital structure later in the timeframe.

Two-Component Disaggregation of ROA

Eli Lilly & Co., decomposition of ROA (quarterly data)

Microsoft Excel
ROA = Net Profit Margin × Asset Turnover
Sep 30, 2025 16.02% = 30.99% × 0.52
Jun 30, 2025 13.67% = 25.91% × 0.53
Mar 31, 2025 12.42% = 22.66% × 0.55
Dec 31, 2024 13.45% = 23.51% × 0.57
Sep 30, 2024 11.07% = 20.48% × 0.54
Jun 30, 2024 10.22% = 18.86% × 0.54
Mar 31, 2024 9.60% = 17.08% × 0.56
Dec 31, 2023 8.19% = 15.36% × 0.53
Sep 30, 2023 8.61% = 15.55% × 0.55
Jun 30, 2023 11.85% = 22.01% × 0.54
Mar 31, 2023 10.70% = 20.54% × 0.52
Dec 31, 2022 12.62% = 21.88% × 0.58
Sep 30, 2022 12.71% = 20.63% × 0.62
Jun 30, 2022 12.09% = 19.58% × 0.62
Mar 31, 2022 13.06% = 20.90% × 0.62
Dec 31, 2021 11.44% = 19.71% × 0.58
Sep 30, 2021 12.39% = 21.52% × 0.58
Jun 30, 2021 12.70% = 22.71% × 0.56
Mar 31, 2021 13.01% = 23.91% × 0.54

Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).


Net Profit Margin
The net profit margin exhibits a fluctuating but generally positive trajectory over the analyzed periods. Beginning at 23.91% in March 2021, it decreased gradually, reaching a low around 15.36% in December 2023. Following this, there is a pronounced recovery, climbing sharply to 30.99% by September 2025. This pattern suggests periods of profitability pressure followed by significant margin improvement in recent quarters.
Asset Turnover
Asset turnover remains relatively stable throughout the timeframe, with minor fluctuations. Starting at 0.54 in March 2021, it peaked at 0.62 during 2022 mid-year but then trended downward, settling near 0.52 by September 2025. The overall stability indicates consistent asset utilization efficiency with a slight decline in recent periods.
Return on Assets (ROA)
The ROA shows a similar pattern to net profit margin but with less volatility. Initial values around 13% decreased to a low of approximately 8.19% in late 2023, followed by steady improvement, reaching 16.02% by September 2025. This trajectory reflects tightening profitability and asset efficiency mid-period, succeeded by enhanced returns in the latest quarters.
Summary
Collectively, the data indicates that while asset efficiency as measured by asset turnover remained mostly constant with a slight decline, profitability indicators experienced more marked fluctuations. Both net profit margin and ROA saw declines through 2023 followed by recovery and growth beyond 2024, suggesting operational improvements or favorable market conditions contributing to stronger profitability and asset returns in the most recent periods.