Stock Analysis on Net

Eli Lilly & Co. (NYSE:LLY)

$24.99

Enterprise Value to EBITDA (EV/EBITDA)

Microsoft Excel

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Earnings before Interest, Tax, Depreciation and Amortization (EBITDA)

Eli Lilly & Co., EBITDA calculation

US$ in millions

Microsoft Excel
12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Net income
Add: Income tax expense
Earnings before tax (EBT)
Add: Interest expense on borrowings
Earnings before interest and tax (EBIT)
Add: Depreciation and amortization
Earnings before interest, tax, depreciation and amortization (EBITDA)

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).


The financial performance indicators demonstrate a consistent upward trend over the five-year period. Net income, Earnings Before Tax (EBT), Earnings Before Interest and Tax (EBIT), and Earnings Before Interest, Tax, Depreciation and Amortization (EBITDA) all exhibit growth from 2021 to 2025. However, the rate of growth varies across the indicators and time periods.

Overall Growth
EBITDA experienced the most substantial growth, increasing from US$8,043 million in 2021 to US$28,623 million in 2025. This represents a cumulative increase of over 255%. EBIT followed a similar trajectory, rising from US$6,495 million to US$26,626 million, a growth of approximately 310%. EBT increased from US$6,156 million to US$25,731 million, representing a growth of over 318%. Net income showed the largest percentage increase, growing from US$5,582 million to US$20,640 million, a substantial increase of approximately 269%.
Growth Rate Analysis
The period between 2022 and 2023 showed relatively modest growth across all indicators. However, a significant acceleration in growth is observed from 2023 to 2024, and this trend continues into 2025. The largest year-over-year increases occur between 2023 and 2024 for all metrics, suggesting a potential inflection point in financial performance. The growth rate appears to be accelerating in the later years of the observed period.
Relationship Between Indicators
The difference between EBITDA and EBIT remained relatively stable in the earlier years (2021-2023), averaging approximately US$1,500 million. However, this difference widens considerably in 2024 and 2025, indicating a potential increase in depreciation and amortization expenses relative to operating income. The gap between EBIT and EBT also widens over time, suggesting increasing interest expenses or other non-operating income/expenses. The relationship between EBT and Net Income remains consistent, reflecting the impact of tax liabilities.

In summary, the financial indicators demonstrate a strong and accelerating growth trend. The substantial increases in EBITDA and net income, coupled with the widening gaps between related metrics, warrant further investigation into the underlying drivers of this performance, including potential changes in cost structures and capital allocation strategies.


Enterprise Value to EBITDA Ratio, Current

Eli Lilly & Co., current EV/EBITDA calculation, comparison to benchmarks

Microsoft Excel
Selected Financial Data (US$ in millions)
Enterprise value (EV)
Earnings before interest, tax, depreciation and amortization (EBITDA)
Valuation Ratio
EV/EBITDA
Benchmarks
EV/EBITDA, Competitors1
AbbVie Inc.
Amgen Inc.
Bristol-Myers Squibb Co.
Danaher Corp.
Gilead Sciences Inc.
Johnson & Johnson
Merck & Co. Inc.
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Thermo Fisher Scientific Inc.
Vertex Pharmaceuticals Inc.
EV/EBITDA, Sector
Pharmaceuticals, Biotechnology & Life Sciences
EV/EBITDA, Industry
Health Care

Based on: 10-K (reporting date: 2025-12-31).

1 Click competitor name to see calculations.

If the company EV/EBITDA is lower then the EV/EBITDA of benchmark then company is relatively undervalued.
Otherwise, if the company EV/EBITDA is higher then the EV/EBITDA of benchmark then company is relatively overvalued.


Enterprise Value to EBITDA Ratio, Historical

Eli Lilly & Co., historical EV/EBITDA calculation, comparison to benchmarks

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Selected Financial Data (US$ in millions)
Enterprise value (EV)1
Earnings before interest, tax, depreciation and amortization (EBITDA)2
Valuation Ratio
EV/EBITDA3
Benchmarks
EV/EBITDA, Competitors4
AbbVie Inc.
Amgen Inc.
Bristol-Myers Squibb Co.
Danaher Corp.
Gilead Sciences Inc.
Johnson & Johnson
Merck & Co. Inc.
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Thermo Fisher Scientific Inc.
Vertex Pharmaceuticals Inc.
EV/EBITDA, Sector
Pharmaceuticals, Biotechnology & Life Sciences
EV/EBITDA, Industry
Health Care

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 See details »

2 See details »

3 2025 Calculation
EV/EBITDA = EV ÷ EBITDA
= ÷ =

4 Click competitor name to see calculations.


The Enterprise Value to EBITDA ratio exhibits significant fluctuation over the observed period. Initially, the ratio increased from 29.86 in 2021 to 37.76 in 2022, indicating a relative increase in enterprise value compared to EBITDA. A substantial surge occurred in 2023, with the ratio reaching 85.35, suggesting a considerable expansion of enterprise value relative to EBITDA. Subsequently, the ratio decreased to 55.99 in 2024 and further declined to 35.45 in 2025.

Enterprise Value
Enterprise Value demonstrates a consistent upward trend throughout the period. Starting at US$240,196 million in 2021, it increased to US$327,011 million in 2022, then experienced a significant jump to US$731,236 million in 2023. This growth continued, reaching US$852,566 million in 2024 and US$1,014,695 million in 2025.
EBITDA
EBITDA showed moderate growth from US$8,043 million in 2021 to US$8,661 million in 2022, followed by a slight decrease to US$8,568 million in 2023. A substantial increase is then observed in 2024, with EBITDA reaching US$15,228 million, and continuing to grow significantly to US$28,623 million in 2025.
EV/EBITDA Ratio – Trend Analysis
The initial increase in the EV/EBITDA ratio between 2021 and 2022 suggests the market was valuing the enterprise at a higher multiple of its earnings. The dramatic increase in 2023, despite only a slight decrease in EBITDA, indicates a substantial re-rating of the enterprise value. The subsequent declines in 2024 and 2025, coinciding with significant EBITDA growth, suggest that while enterprise value continued to rise, EBITDA grew at a faster rate, leading to a lower valuation multiple. This could indicate increasing investor confidence in the company’s earnings potential.

The observed pattern suggests a dynamic relationship between enterprise value and EBITDA, with enterprise value growth initially outpacing EBITDA, then being overtaken by more substantial EBITDA increases in later years. The ratio’s movement warrants further investigation into the underlying drivers of both enterprise value and EBITDA.