Stock Analysis on Net

Amgen Inc. (NASDAQ:AMGN)

$24.99

Enterprise Value to EBITDA (EV/EBITDA)

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Earnings before Interest, Tax, Depreciation and Amortization (EBITDA)

Amgen Inc., EBITDA calculation

US$ in millions

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12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Net income
Add: Income tax expense
Earnings before tax (EBT)
Add: Interest expense, net
Earnings before interest and tax (EBIT)
Add: Depreciation, amortization and other
Earnings before interest, tax, depreciation and amortization (EBITDA)

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).


The financial performance indicators demonstrate a generally positive trajectory over the five-year period, with some fluctuation observed in 2024. Earnings metrics consistently increased from 2021 to 2023, before experiencing a decline in 2024, and then recovering strongly in 2025.

Overall Earnings Growth
Net income increased from US$5,893 million in 2021 to US$7,711 million in 2025, representing a cumulative growth of approximately 31%. This growth was not linear, with a notable decrease in 2024 before a substantial rebound. Earnings before tax followed a similar pattern, rising from US$6,701 million to US$8,976 million over the same period, a growth of roughly 34%.
EBIT Trend
Earnings before interest and tax (EBIT) exhibited strong growth from US$7,898 million in 2021 to US$11,731 million in 2025, a cumulative increase of approximately 49%. The year 2024 saw a decrease to US$7,764 million, but this was followed by a significant recovery in 2025. This suggests operational performance is a key driver of overall profitability.
EBITDA Performance
Earnings before interest, tax, depreciation, and amortization (EBITDA) increased from US$11,296 million in 2021 to US$16,898 million in 2025, representing a cumulative growth of approximately 49.8%. Similar to other earnings metrics, EBITDA experienced a decline in 2024, falling to US$13,356 million, before a strong recovery in 2025. The consistency of EBITDA growth, even with the 2024 dip, indicates a robust underlying operational cash flow generation capability.

The decline in earnings metrics during 2024 warrants further investigation to determine the underlying causes. However, the subsequent strong recovery in 2025 suggests that the factors impacting 2024 performance were potentially temporary or successfully addressed. The overall trend indicates a company with improving profitability and operational efficiency.


Enterprise Value to EBITDA Ratio, Current

Amgen Inc., current EV/EBITDA calculation, comparison to benchmarks

Microsoft Excel
Selected Financial Data (US$ in millions)
Enterprise value (EV)
Earnings before interest, tax, depreciation and amortization (EBITDA)
Valuation Ratio
EV/EBITDA
Benchmarks
EV/EBITDA, Competitors1
AbbVie Inc.
Bristol-Myers Squibb Co.
Danaher Corp.
Eli Lilly & Co.
Gilead Sciences Inc.
Johnson & Johnson
Merck & Co. Inc.
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Thermo Fisher Scientific Inc.
Vertex Pharmaceuticals Inc.
EV/EBITDA, Sector
Pharmaceuticals, Biotechnology & Life Sciences
EV/EBITDA, Industry
Health Care

Based on: 10-K (reporting date: 2025-12-31).

1 Click competitor name to see calculations.

If the company EV/EBITDA is lower then the EV/EBITDA of benchmark then company is relatively undervalued.
Otherwise, if the company EV/EBITDA is higher then the EV/EBITDA of benchmark then company is relatively overvalued.


Enterprise Value to EBITDA Ratio, Historical

Amgen Inc., historical EV/EBITDA calculation, comparison to benchmarks

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Selected Financial Data (US$ in millions)
Enterprise value (EV)1
Earnings before interest, tax, depreciation and amortization (EBITDA)2
Valuation Ratio
EV/EBITDA3
Benchmarks
EV/EBITDA, Competitors4
AbbVie Inc.
Bristol-Myers Squibb Co.
Danaher Corp.
Eli Lilly & Co.
Gilead Sciences Inc.
Johnson & Johnson
Merck & Co. Inc.
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Thermo Fisher Scientific Inc.
Vertex Pharmaceuticals Inc.
EV/EBITDA, Sector
Pharmaceuticals, Biotechnology & Life Sciences
EV/EBITDA, Industry
Health Care

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 See details »

2 See details »

3 2025 Calculation
EV/EBITDA = EV ÷ EBITDA
= ÷ =

4 Click competitor name to see calculations.


The Enterprise Value to EBITDA ratio exhibited fluctuations over the five-year period. Initially, the ratio decreased slightly before increasing and then decreasing again, suggesting evolving market perceptions of the company’s value relative to its operational cash flow.

Enterprise Value (EV)
Enterprise Value demonstrated an overall upward trend, increasing from US$149,300 million in 2021 to US$244,493 million in 2025. However, a slight decrease was observed between 2023 and 2024, from US$209,123 million to US$204,539 million, before resuming growth in the final year.
Earnings Before Interest, Tax, Depreciation, and Amortization (EBITDA)
EBITDA generally increased throughout the period, rising from US$11,296 million in 2021 to US$16,898 million in 2025. A dip occurred between 2023 and 2024, with EBITDA decreasing from US$14,801 million to US$13,356 million, but it recovered strongly in the subsequent year.
EV/EBITDA Ratio
The EV/EBITDA ratio began at 13.22 in 2021 and decreased to 12.97 in 2022. It then increased to 14.13 in 2023, followed by a rise to 15.31 in 2024, representing the highest value within the observed timeframe. The ratio concluded the period at 14.47 in 2025, indicating a slight decrease from its peak. The fluctuations suggest a dynamic relationship between the company’s enterprise value and its earnings generation capacity.

The observed increase in the EV/EBITDA ratio in 2024, despite a decrease in EBITDA, suggests that the market may have increased its expectations for future growth or perceived a higher level of risk associated with the company. The subsequent decrease in 2025, coinciding with a rise in EBITDA, indicates a potential recalibration of market valuation.