Stock Analysis on Net

Thermo Fisher Scientific Inc. (NYSE:TMO)

$24.99

Economic Value Added (EVA)

Microsoft Excel

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Economic Profit

Thermo Fisher Scientific Inc., economic profit calculation

US$ in millions

Microsoft Excel
12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Net operating profit after taxes (NOPAT)1
Cost of capital2
Invested capital3
 
Economic profit4

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 NOPAT. See details »

2 Cost of capital. See details »

3 Invested capital. See details »

4 2025 Calculation
Economic profit = NOPAT – Cost of capital × Invested capital
= × =


An analysis of economic profit reveals a sustained period of value destruction from 2021 through 2025, characterized by consistently negative economic profit figures. The deficit widened significantly between 2021 and 2023 before entering a phase of relative volatility, indicating that the returns generated from operations were insufficient to cover the cost of the capital employed.

Net Operating Profit After Taxes (NOPAT)
A downward trend in NOPAT is observed from 2021 to 2023, where values declined from 7,514 million to 5,117 million. A recovery phase followed in 2024 and 2025, with NOPAT increasing to 6,467 million by the end of the period. Despite this recovery, the 2025 figure remains below the initial 2021 level.
Invested Capital and Cost of Capital
Invested capital experienced an overall increase, rising from 79,776 million in 2021 to 94,150 million in 2025, with a temporary decrease observed in 2024. Simultaneously, the cost of capital remained remarkably stable, fluctuating within a narrow range between 14.23% and 14.74%. The growth in the invested capital base, paired with a stable cost of capital, increased the total capital charge that NOPAT needed to exceed to generate a positive economic profit.
Economic Profit Trajectory
Economic profit deteriorated from -3,877 million in 2021 to its lowest point of -7,384 million in 2023. Although a slight improvement occurred in 2024, the figure declined again to -6,934 million in 2025. The persistence of these negative values confirms that the return on invested capital remained consistently below the cost of capital throughout the analyzed timeframe.


Net Operating Profit after Taxes (NOPAT)

Thermo Fisher Scientific Inc., NOPAT calculation

US$ in millions

Microsoft Excel
12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Net income attributable to Thermo Fisher Scientific Inc.
Deferred income tax expense (benefit)1
Increase (decrease) in allowances2
Increase (decrease) in accrued restructuring costs3
Increase (decrease) in equity equivalents4
Interest expense
Interest expense, operating lease liability5
Adjusted interest expense
Tax benefit of interest expense6
Adjusted interest expense, after taxes7
Interest income
Investment income, before taxes
Tax expense (benefit) of investment income8
Investment income, after taxes9
Net income (loss) attributable to noncontrolling interest
Net operating profit after taxes (NOPAT)

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 Elimination of deferred tax expense. See details »

2 Addition of increase (decrease) in allowances.

3 Addition of increase (decrease) in accrued restructuring costs.

4 Addition of increase (decrease) in equity equivalents to net income attributable to Thermo Fisher Scientific Inc..

5 2025 Calculation
Interest expense on capitalized operating leases = Operating lease liability × Discount rate
= × =

6 2025 Calculation
Tax benefit of interest expense = Adjusted interest expense × Statutory income tax rate
= × 21.00% =

7 Addition of after taxes interest expense to net income attributable to Thermo Fisher Scientific Inc..

8 2025 Calculation
Tax expense (benefit) of investment income = Investment income, before tax × Statutory income tax rate
= × 21.00% =

9 Elimination of after taxes investment income.


Net income attributable to Thermo Fisher Scientific Inc. and Net Operating Profit After Taxes (NOPAT) both demonstrate fluctuations over the five-year period. While net income shows a relatively stable pattern, NOPAT exhibits a more pronounced decline followed by recovery.

Net Income Trend
Net income attributable to Thermo Fisher Scientific Inc. decreased from US$7,725 million in 2021 to US$6,950 million in 2022. A further decrease was observed in 2023, reaching US$5,995 million. Subsequently, net income increased to US$6,335 million in 2024 and continued to rise to US$6,704 million in 2025, though it did not return to the 2021 level.
NOPAT Trend
NOPAT experienced a more significant decline than net income. Starting at US$7,514 million in 2021, it decreased to US$6,425 million in 2022. The decline accelerated in 2023, falling to US$5,117 million. A modest recovery occurred in 2024, with NOPAT reaching US$5,400 million. The most substantial increase within the observed period occurred between 2024 and 2025, with NOPAT rising to US$6,467 million. Despite this recovery, the 2025 NOPAT figure remains below the 2021 level.
Relationship between Net Income and NOPAT
The values for net income and NOPAT are closely aligned throughout the period, suggesting a limited impact from financing costs or non-operating items. The proportional changes in both metrics are similar, indicating that the core operating profitability is the primary driver of overall profitability. However, the magnitude of the NOPAT decline in 2023 was greater than that of net income, potentially indicating changes in the tax rate or other adjustments between net income and NOPAT.

The recovery in both net income and NOPAT in the later years of the period suggests a potential stabilization or improvement in the company’s operating performance. Further investigation would be required to determine the underlying causes of these fluctuations and the sustainability of the recent recovery.



Cash Operating Taxes

Thermo Fisher Scientific Inc., cash operating taxes calculation

US$ in millions

Microsoft Excel
12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Provision for income taxes
Less: Deferred income tax expense (benefit)
Add: Tax savings from interest expense
Less: Tax imposed on investment income
Cash operating taxes

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).


The provision for income taxes and cash operating taxes exhibited distinct trends between 2021 and 2025. A significant decrease in the provision for income taxes is apparent over the period, while cash operating taxes demonstrate more fluctuation.

Provision for Income Taxes
The provision for income taxes decreased substantially from US$1,109 million in 2021 to US$284 million in 2023. A moderate increase was then observed in 2024, reaching US$657 million, followed by a further decrease to US$547 million in 2025. This represents an overall decline of approximately 50.7% from 2021 to 2025.
Cash Operating Taxes
Cash operating taxes remained relatively stable between 2021 and 2023, fluctuating around US$1,800 million. A notable increase occurred in 2024, with cash operating taxes rising to US$1,946 million. However, a considerable decrease was recorded in 2025, falling to US$1,290 million. The net change from 2021 to 2025 is a decrease of approximately 30.9%.

The divergence between the provision for income taxes and cash operating taxes suggests potential differences in temporary versus permanent tax differences. The substantial reduction in the provision for income taxes, coupled with the fluctuating cash operating taxes, warrants further investigation into the underlying factors driving these trends, such as changes in tax regulations, deferred tax asset realization, or shifts in the composition of taxable income.

Relationship between Provision and Cash Taxes
In 2021, cash operating taxes exceeded the provision for income taxes by US$757 million. This difference narrowed in 2022 to US$1,103 million and further decreased in 2023 to US$1,417 million. The gap widened again in 2024 to US$1,289 million before decreasing significantly in 2025 to US$743 million. This fluctuating difference highlights the impact of timing differences between reported income tax expense and actual cash tax payments.

The observed trends indicate a complex tax profile, and continued monitoring of these figures is recommended to assess potential impacts on future cash flows and overall financial performance.



Invested Capital

Thermo Fisher Scientific Inc., invested capital calculation (financing approach)

US$ in millions

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Short-term obligations and current maturities of long-term obligations
Long-term obligations, excluding current maturities
Operating lease liability1
Total reported debt & leases
Total Thermo Fisher Scientific Inc. shareholders’ equity
Net deferred tax (assets) liabilities2
Allowances3
Accrued restructuring costs4
Equity equivalents5
Accumulated other comprehensive (income) loss, net of tax6
Redeemable noncontrolling interest
Noncontrolling interests
Adjusted total Thermo Fisher Scientific Inc. shareholders’ equity
Construction in progress7
Investments measured at fair value on a recurring basis8
Invested capital

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 Addition of capitalized operating leases.

2 Elimination of deferred taxes from assets and liabilities. See details »

3 Addition of allowance for doubtful accounts receivable.

4 Addition of accrued restructuring costs.

5 Addition of equity equivalents to total Thermo Fisher Scientific Inc. shareholders’ equity.

6 Removal of accumulated other comprehensive income.

7 Subtraction of construction in progress.

8 Subtraction of investments measured at fair value on a recurring basis.


The invested capital of the company demonstrates an overall increasing trend between 2021 and 2025, though with some fluctuation. Total reported debt & leases and total shareholders’ equity both contribute to this figure, and their individual movements influence the overall invested capital.

Invested Capital Trend
Invested capital increased from US$79,776 million in 2021 to US$82,814 million in 2022, representing a growth of approximately 3.8%. Further growth was observed in 2023, reaching US$85,573 million. A slight decrease occurred in 2024, with invested capital falling to US$82,071 million. However, a significant increase is noted in 2025, with invested capital reaching US$94,150 million.
Debt & Leases
Total reported debt & leases remained relatively stable between 2021 and 2023, fluctuating around US$36 billion. A decrease was observed in 2024, falling to US$32,775 million. This downward trend was reversed in 2025, with debt & leases increasing substantially to US$40,855 million.
Shareholders’ Equity
Total shareholders’ equity exhibited consistent growth throughout the period. It increased from US$40,793 million in 2021 to US$43,978 million in 2022, US$46,735 million in 2023, and US$49,584 million in 2024. This growth continued into 2025, reaching US$53,407 million. The consistent increase in shareholders’ equity contributes to the overall growth in invested capital.

The increase in invested capital in 2025 is primarily driven by a substantial rise in debt & leases, despite continued growth in shareholders’ equity. The dip in invested capital in 2024 is attributable to the decrease in debt & leases, partially offset by the continued growth in shareholders’ equity. These fluctuations suggest potential shifts in the company’s capital structure and financing strategies.


Cost of Capital

Thermo Fisher Scientific Inc., cost of capital calculations

Capital (fair value)1 Weights Cost of capital
Equity2 ÷ = × =
Debt obligations3 ÷ = × × (1 – 21.00%) =
Operating lease liability4 ÷ = × × (1 – 21.00%) =
Total:

Based on: 10-K (reporting date: 2025-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt obligations. See details »

4 Operating lease liability. See details »

Capital (fair value)1 Weights Cost of capital
Equity2 ÷ = × =
Debt obligations3 ÷ = × × (1 – 21.00%) =
Operating lease liability4 ÷ = × × (1 – 21.00%) =
Total:

Based on: 10-K (reporting date: 2024-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt obligations. See details »

4 Operating lease liability. See details »

Capital (fair value)1 Weights Cost of capital
Equity2 ÷ = × =
Debt obligations3 ÷ = × × (1 – 21.00%) =
Operating lease liability4 ÷ = × × (1 – 21.00%) =
Total:

Based on: 10-K (reporting date: 2023-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt obligations. See details »

4 Operating lease liability. See details »

Capital (fair value)1 Weights Cost of capital
Equity2 ÷ = × =
Debt obligations3 ÷ = × × (1 – 21.00%) =
Operating lease liability4 ÷ = × × (1 – 21.00%) =
Total:

Based on: 10-K (reporting date: 2022-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt obligations. See details »

4 Operating lease liability. See details »

Capital (fair value)1 Weights Cost of capital
Equity2 ÷ = × =
Debt obligations3 ÷ = × × (1 – 21.00%) =
Operating lease liability4 ÷ = × × (1 – 21.00%) =
Total:

Based on: 10-K (reporting date: 2021-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt obligations. See details »

4 Operating lease liability. See details »


Economic Spread Ratio

Thermo Fisher Scientific Inc., economic spread ratio calculation, comparison to benchmarks

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Selected Financial Data (US$ in millions)
Economic profit1
Invested capital2
Performance Ratio
Economic spread ratio3
Benchmarks
Economic Spread Ratio, Competitors4
AbbVie Inc.
Amgen Inc.
Bristol-Myers Squibb Co.
Danaher Corp.
Eli Lilly & Co.
Gilead Sciences Inc.
Johnson & Johnson
Merck & Co. Inc.
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Vertex Pharmaceuticals Inc.

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 Economic profit. See details »

2 Invested capital. See details »

3 2025 Calculation
Economic spread ratio = 100 × Economic profit ÷ Invested capital
= 100 × ÷ =

4 Click competitor name to see calculations.


A period of consistent negative economic value creation is observed between 2021 and 2025. The organization has operated with a return on invested capital that remains below its cost of capital, resulting in persistent negative economic profit and a negative economic spread ratio throughout the analyzed timeframe.

Economic Profit Trends
Economic profit experienced a significant decline from 2021 to 2023, with the deficit widening from 3,877 million US$ to a peak of 7,384 million US$. A slight moderation in this deficit occurred in 2024, reaching 6,695 million US$, before shifting slightly back to 6,934 million US$ by the end of 2025.
Invested Capital Dynamics
Invested capital exhibited a general upward trajectory over the five-year period, increasing from 79,776 million US$ in 2021 to 94,150 million US$ in 2025. A temporary contraction was noted in 2024, where capital decreased to 82,071 million US$, followed by the most substantial year-over-year increase in 2025.
Economic Spread Ratio Analysis
The economic spread ratio remained negative, confirming that the actual return on capital did not meet the required hurdle rate. The spread deteriorated from -4.86% in 2021 to its lowest point of -8.63% in 2023. Since that trough, a gradual corrective trend is observed, with the ratio improving to -8.16% in 2024 and -7.36% in 2025, suggesting a slow narrowing of the gap between the return on invested capital and the cost of capital.

Economic Profit Margin

Thermo Fisher Scientific Inc., economic profit margin calculation, comparison to benchmarks

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Selected Financial Data (US$ in millions)
Economic profit1
Revenues
Performance Ratio
Economic profit margin2
Benchmarks
Economic Profit Margin, Competitors3
AbbVie Inc.
Amgen Inc.
Bristol-Myers Squibb Co.
Danaher Corp.
Eli Lilly & Co.
Gilead Sciences Inc.
Johnson & Johnson
Merck & Co. Inc.
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Vertex Pharmaceuticals Inc.

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 Economic profit. See details »

2 2025 Calculation
Economic profit margin = 100 × Economic profit ÷ Revenues
= 100 × ÷ =

3 Click competitor name to see calculations.


An analysis of the economic value added reveals a consistent failure to generate positive economic profit over the observed five-year period. The entity has operated with a negative economic profit throughout the duration, indicating that returns generated were insufficient to cover the cost of capital employed.

Economic Profit Trends
Economic losses expanded steadily from December 31, 2021, reaching a peak deficit of US$ 7,384 million by December 31, 2023. Although a slight reduction in loss occurred in 2024, the economic profit remained negative, concluding the period at a loss of US$ 6,934 million in 2025.
Revenue Dynamics
Revenues exhibited volatility, increasing from US$ 39,211 million in 2021 to a peak of US$ 44,915 million in 2022, before experiencing a contraction in 2023 and 2024. A recovery was noted by the end of 2025, with revenues rising to US$ 44,556 million; however, this growth did not translate into positive economic value creation.
Economic Profit Margin Analysis
The economic profit margin deteriorated significantly from -9.89% in 2021 to its lowest point of -17.23% in 2023. A period of relative stabilization followed, with margins improving slightly to -15.61% in 2024 and -15.56% in 2025. The persistent negative margins suggest a systemic gap between operating performance and the required rate of return on invested capital.