Stock Analysis on Net

AbbVie Inc. (NYSE:ABBV)

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Economic Value Added (EVA)

Microsoft Excel

Economic Profit

AbbVie Inc., economic profit calculation

US$ in millions

Microsoft Excel
12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Net operating profit after taxes (NOPAT)1 5,919 4,563 3,292 11,543 12,362
Cost of capital2 8.72% 8.60% 8.55% 8.37% 7.84%
Invested capital3 61,356 69,263 68,204 82,134 95,922
 
Economic profit4 567 (1,396) (2,543) 4,670 4,843

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 NOPAT. See details »

2 Cost of capital. See details »

3 Invested capital. See details »

4 2025 Calculation
Economic profit = NOPAT – Cost of capital × Invested capital
= 5,9198.72% × 61,356 = 567


A comprehensive review of financial performance from 2021 to 2025 reveals a period of significant volatility in economic profit. While the company initiated the period creating substantial value, a sharp contraction in operating performance in 2023 led to a two-year interval of value destruction, followed by a return to positive economic profit by the end of 2025.

Net Operating Profit After Taxes (NOPAT)
A precipitous decline in NOPAT is observed in 2023, falling to 3,292 million from 11,543 million in the previous year. A gradual recovery trend followed, with NOPAT increasing to 4,563 million in 2024 and 5,919 million in 2025, although these levels remain significantly lower than those recorded in 2021 and 2022.
Cost of Capital
The cost of capital exhibited a consistent upward trajectory throughout the analyzed period, rising steadily from 7.84% in 2021 to 8.72% in 2025. This persistent increase indicates a rising hurdle rate, which placed additional pressure on the company's ability to generate positive economic profit.
Invested Capital
A general downward trend in invested capital is evident, decreasing from 95,922 million in 2021 to 61,356 million in 2025. Aside from a marginal increase in 2024, the reduction in the capital base suggests a contraction in the assets employed to generate operating returns.
Economic Profit
Economic profit transitioned from strong positive values in 2021 and 2022 to negative territory in 2023 and 2024, marking a period where the NOPAT was insufficient to cover the cost of invested capital. The lowest point occurred in 2023 with an economic profit of -2,543 million. The combination of recovering operating profits and a reduced capital base allowed for a return to positive value creation in 2025, reaching 567 million.

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Net Operating Profit after Taxes (NOPAT)

AbbVie Inc., NOPAT calculation

US$ in millions

Microsoft Excel
12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Net earnings attributable to AbbVie Inc. 4,226 4,278 4,863 11,836 11,542
Deferred income tax expense (benefit)1 (492) (1,449) (2,889) (1,931) (898)
Increase (decrease) in restructuring reserve2 78 (3) (44) (5) (189)
Increase (decrease) in equity equivalents3 (414) (1,452) (2,933) (1,936) (1,087)
Interest expense 2,893 2,808 2,224 2,230 2,423
Interest expense, operating lease liability4 31 29 27 24 21
Adjusted interest expense 2,924 2,837 2,251 2,254 2,444
Tax benefit of interest expense5 (614) (596) (473) (473) (513)
Adjusted interest expense, after taxes6 2,310 2,241 1,778 1,781 1,931
Interest income (266) (648) (540) (186) (39)
Investment income, before taxes (266) (648) (540) (186) (39)
Tax expense (benefit) of investment income7 56 136 113 39 8
Investment income, after taxes8 (210) (512) (427) (147) (31)
Net income (loss) attributable to noncontrolling interest 7 8 10 9 7
Net operating profit after taxes (NOPAT) 5,919 4,563 3,292 11,543 12,362

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 Elimination of deferred tax expense. See details »

2 Addition of increase (decrease) in restructuring reserve.

3 Addition of increase (decrease) in equity equivalents to net earnings attributable to AbbVie Inc..

4 2025 Calculation
Interest expense on capitalized operating leases = Operating lease liability × Discount rate
= 883 × 3.50% = 31

5 2025 Calculation
Tax benefit of interest expense = Adjusted interest expense × Statutory income tax rate
= 2,924 × 21.00% = 614

6 Addition of after taxes interest expense to net earnings attributable to AbbVie Inc..

7 2025 Calculation
Tax expense (benefit) of investment income = Investment income, before tax × Statutory income tax rate
= 266 × 21.00% = 56

8 Elimination of after taxes investment income.


Net earnings attributable to AbbVie Inc. exhibited an initial increase from 2021 to 2022, followed by a substantial decline in 2023 and a slight recovery in 2024 and 2025. However, the trend in net operating profit after taxes (NOPAT) presents a different pattern. NOPAT decreased from 2021 to 2023, then increased significantly in 2024 and 2025.

NOPAT Trend
NOPAT began at US$12,362 million in 2021, decreasing to US$11,543 million in 2022, representing a decline of approximately 6.7%. A more pronounced decrease occurred in 2023, with NOPAT falling to US$3,292 million. This represents a substantial reduction of over 71% from the 2022 value. A recovery is then observed in 2024, with NOPAT rising to US$4,563 million, and continuing upward in 2025 to reach US$5,919 million. The 2025 value, while representing a significant improvement from 2023, remains below the levels seen in 2021 and 2022.

The divergence between the trends in net earnings and NOPAT suggests potential shifts in the company’s capital structure or non-operating items. While net earnings decreased significantly in 2023, the NOPAT decline was even more substantial, indicating that factors beyond core operating profitability contributed to the reduction in net income. The subsequent recovery in NOPAT, exceeding the recovery in net earnings, suggests improvements in operational efficiency or changes in the cost of capital may be influencing the results.

Relationship between NOPAT and Net Earnings
In 2021 and 2022, NOPAT was consistently higher than net earnings attributable to AbbVie Inc. However, this relationship changed in 2023 and 2024, where net earnings exceeded NOPAT. By 2025, net earnings and NOPAT were relatively close, but net earnings remained slightly higher. This difference could be attributed to items such as interest expense, taxes, and other non-operating income or expenses.

The substantial fluctuations in NOPAT warrant further investigation to understand the underlying drivers. A detailed analysis of the components of NOPAT, including operating revenue, operating expenses, and tax rates, would be necessary to pinpoint the specific factors contributing to these changes.

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Cash Operating Taxes

AbbVie Inc., cash operating taxes calculation

US$ in millions

Microsoft Excel
12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Income tax expense (benefit) 2,364 (570) 1,377 1,632 1,440
Less: Deferred income tax expense (benefit) (492) (1,449) (2,889) (1,931) (898)
Add: Tax savings from interest expense 614 596 473 473 513
Less: Tax imposed on investment income 56 136 113 39 8
Cash operating taxes 3,414 1,339 4,625 3,997 2,843

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).


The reported income tax expense and cash operating taxes exhibit distinct trends over the five-year period. Income tax expense fluctuates considerably, while cash operating taxes generally increase, though with notable variations.

Income Tax Expense
Income tax expense increased from US$1,440 million in 2021 to US$1,632 million in 2022, representing a rise of approximately 13.3%. A subsequent decrease was observed in 2023, with expense falling to US$1,377 million. A significant shift occurred in 2024, resulting in a tax benefit of US$570 million. This was followed by a substantial increase in expense to US$2,364 million in 2025. The volatility suggests potential impacts from changes in tax laws, deferred tax asset adjustments, or significant shifts in pre-tax income.
Cash Operating Taxes
Cash operating taxes demonstrate an overall upward trend, although not consistently. The amount rose from US$2,843 million in 2021 to US$3,997 million in 2022, an increase of approximately 40.6%. Further growth was seen in 2023, reaching US$4,625 million. A considerable decline occurred in 2024, with cash taxes decreasing to US$1,339 million. The final year, 2025, shows a recovery to US$3,414 million. The fluctuations in cash taxes are likely influenced by timing differences between income tax expense and actual cash payments, as well as potential tax planning strategies.
Relationship between Income Tax Expense and Cash Operating Taxes
A divergence is apparent between the two measures. While income tax expense is reported on the income statement based on accounting standards, cash operating taxes reflect the actual cash outflows for taxes. The significant difference in 2024, where an income tax benefit is recorded alongside a cash outflow, indicates substantial deferred tax impacts or tax credits being utilized. The generally higher level of cash taxes compared to income tax expense throughout the period suggests the company may be utilizing tax loss carryforwards or experiencing temporary differences that result in higher cash payments than reported expense.

The observed patterns warrant further investigation into the underlying drivers of these fluctuations, particularly the significant changes in 2024 and 2025, to fully understand their implications for the company’s financial position and future cash flows.

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Invested Capital

AbbVie Inc., invested capital calculation (financing approach)

US$ in millions

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Short-term borrowings 2,499 1 14
Current portion of long-term debt and finance lease obligations 6,056 6,804 7,191 4,135 12,481
Long-term debt and finance lease obligations, excluding current portion 58,941 60,340 52,194 59,135 64,189
Operating lease liability1 883 875 901 920 891
Total reported debt & leases 68,379 68,019 60,286 64,191 77,575
Stockholders’ equity (deficit) (3,270) 3,325 10,360 17,254 15,408
Net deferred tax (assets) liabilities2 (3,715) (3,047) (3,803) (830) 735
Restructuring reserve3 314 236 239 283 288
Equity equivalents4 (3,401) (2,811) (3,564) (547) 1,023
Accumulated other comprehensive (income) loss, net of tax5 1,144 1,925 2,305 2,199 2,899
Noncontrolling interest 42 39 37 33 28
Adjusted stockholders’ equity (deficit) (5,485) 2,478 9,138 18,939 19,358
Construction in progress6 (1,401) (1,093) (1,073) (856) (799)
Available-for-sale investment securities7 (137) (141) (147) (140) (212)
Invested capital 61,356 69,263 68,204 82,134 95,922

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 Addition of capitalized operating leases.

2 Elimination of deferred taxes from assets and liabilities. See details »

3 Addition of restructuring reserve.

4 Addition of equity equivalents to stockholders’ equity (deficit).

5 Removal of accumulated other comprehensive income.

6 Subtraction of construction in progress.

7 Subtraction of available-for-sale investment securities.


The reported invested capital demonstrates a declining trend over the five-year period. Total reported debt & leases and stockholders’ equity both contribute to the calculation of invested capital, and changes in these components influence the overall trend.

Invested Capital Trend
Invested capital decreased from US$95,922 million in 2021 to US$61,356 million in 2025. The most significant decrease occurred between 2022 and 2023, falling from US$82,134 million to US$68,204 million. A smaller decrease was observed between 2021 and 2022. A slight increase occurred between 2023 and 2024, followed by a further decrease in 2025.
Debt & Leases
Total reported debt & leases decreased from US$77,575 million in 2021 to US$64,191 million in 2022, continuing to US$60,286 million in 2023. An increase to US$68,019 million was noted in 2024, followed by a marginal increase to US$68,379 million in 2025. While fluctuating, the level of debt remained relatively stable between 2024 and 2025.
Stockholders’ Equity
Stockholders’ equity increased from US$15,408 million in 2021 to US$17,254 million in 2022. However, a substantial decline was observed in subsequent years, decreasing to US$10,360 million in 2023, US$3,325 million in 2024, and ultimately reaching a deficit of US$-3,270 million in 2025. This negative equity position in the final year represents a significant shift.

The decrease in invested capital appears to be primarily driven by the substantial reduction in stockholders’ equity, particularly in the later years of the period. While debt levels decreased initially, they stabilized and even increased slightly in the most recent years, suggesting that debt reduction is not the primary driver of the overall decline in invested capital. The transition to negative stockholders’ equity in 2025 is a notable development that warrants further investigation.

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Cost of Capital

AbbVie Inc., cost of capital calculations

Capital (fair value)1 Weights Cost of capital
Equity2 397,502 397,502 ÷ 463,020 = 0.86 0.86 × 9.61% = 8.25%
Debt and finance lease obligations3 64,635 64,635 ÷ 463,020 = 0.14 0.14 × 4.21% × (1 – 21.00%) = 0.46%
Operating lease liability4 883 883 ÷ 463,020 = 0.00 0.00 × 3.50% × (1 – 21.00%) = 0.01%
Total: 463,020 1.00 8.72%

Based on: 10-K (reporting date: 2025-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt and finance lease obligations. See details »

4 Operating lease liability. See details »

Capital (fair value)1 Weights Cost of capital
Equity2 340,484 340,484 ÷ 404,066 = 0.84 0.84 × 9.61% = 8.10%
Debt and finance lease obligations3 62,707 62,707 ÷ 404,066 = 0.16 0.16 × 4.05% × (1 – 21.00%) = 0.50%
Operating lease liability4 875 875 ÷ 404,066 = 0.00 0.00 × 3.30% × (1 – 21.00%) = 0.01%
Total: 404,066 1.00 8.60%

Based on: 10-K (reporting date: 2024-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt and finance lease obligations. See details »

4 Operating lease liability. See details »

Capital (fair value)1 Weights Cost of capital
Equity2 310,458 310,458 ÷ 367,703 = 0.84 0.84 × 9.61% = 8.12%
Debt and finance lease obligations3 56,344 56,344 ÷ 367,703 = 0.15 0.15 × 3.57% × (1 – 21.00%) = 0.43%
Operating lease liability4 901 901 ÷ 367,703 = 0.00 0.00 × 3.00% × (1 – 21.00%) = 0.01%
Total: 367,703 1.00 8.55%

Based on: 10-K (reporting date: 2023-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt and finance lease obligations. See details »

4 Operating lease liability. See details »

Capital (fair value)1 Weights Cost of capital
Equity2 267,728 267,728 ÷ 326,497 = 0.82 0.82 × 9.61% = 7.88%
Debt and finance lease obligations3 57,849 57,849 ÷ 326,497 = 0.18 0.18 × 3.42% × (1 – 21.00%) = 0.48%
Operating lease liability4 920 920 ÷ 326,497 = 0.00 0.00 × 2.60% × (1 – 21.00%) = 0.01%
Total: 326,497 1.00 8.37%

Based on: 10-K (reporting date: 2022-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt and finance lease obligations. See details »

4 Operating lease liability. See details »

Capital (fair value)1 Weights Cost of capital
Equity2 254,754 254,754 ÷ 339,401 = 0.75 0.75 × 9.61% = 7.22%
Debt and finance lease obligations3 83,756 83,756 ÷ 339,401 = 0.25 0.25 × 3.17% × (1 – 21.00%) = 0.62%
Operating lease liability4 891 891 ÷ 339,401 = 0.00 0.00 × 2.40% × (1 – 21.00%) = 0.00%
Total: 339,401 1.00 7.84%

Based on: 10-K (reporting date: 2021-12-31).

1 US$ in millions

2 Equity. See details »

3 Debt and finance lease obligations. See details »

4 Operating lease liability. See details »



Economic Spread Ratio

AbbVie Inc., economic spread ratio calculation, comparison to benchmarks

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Selected Financial Data (US$ in millions)
Economic profit1 567 (1,396) (2,543) 4,670 4,843
Invested capital2 61,356 69,263 68,204 82,134 95,922
Performance Ratio
Economic spread ratio3 0.92% -2.01% -3.73% 5.69% 5.05%
Benchmarks
Economic Spread Ratio, Competitors4
Amgen Inc. 6.40% -0.40% 2.41% 6.95% 6.94%
Bristol-Myers Squibb Co. 5.87% -21.81% 1.75% -0.98% 1.30%
Danaher Corp. -10.74% -10.91% -11.68% -6.67% -5.84%
Eli Lilly & Co. 30.38% 14.72% 1.65% 8.75% 10.41%
Gilead Sciences Inc. 12.83% -10.26% 3.05% -0.07% 6.93%
Johnson & Johnson 11.78% 2.11% 0.26% 5.52% 10.59%
Merck & Co. Inc. 10.74% 13.62% -8.67% 11.51% 11.65%
Pfizer Inc. -3.56% -3.24% -9.35% 18.13% 11.30%
Regeneron Pharmaceuticals Inc. 14.03% 16.85% 13.65% 19.02% 62.77%
Thermo Fisher Scientific Inc. -7.48% -8.28% -8.75% -7.00% -4.98%
Vertex Pharmaceuticals Inc. 21.07% -22.58% 11.36% 14.11% 15.32%

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 Economic profit. See details »

2 Invested capital. See details »

3 2025 Calculation
Economic spread ratio = 100 × Economic profit ÷ Invested capital
= 100 × 567 ÷ 61,356 = 0.92%

4 Click competitor name to see calculations.


The financial performance between 2021 and 2025 is characterized by a significant period of value erosion followed by a nascent recovery. The trajectory indicates a shift from strong value creation to a phase of negative economic returns, concluding with a return to positive economic profit.

Economic Spread Ratio
The spread ratio demonstrates a sharp volatility cycle. An initial increase from 5.05% in 2021 to 5.69% in 2022 suggests an expanding margin between the return on invested capital and the cost of capital. This was followed by a severe collapse in 2023, where the ratio dropped to -3.73%, indicating that the cost of capital significantly exceeded returns. A gradual recovery is evident in 2024 (-2.01%) and 2025 (0.92%), though the level of value creation in the final year remains substantially lower than the 2021-2022 baseline.
Invested Capital
A consistent downward trend in invested capital is observed over the five-year period. Capital decreased from 95,922 million US$ in 2021 to 61,356 million US$ in 2025, representing a total reduction of approximately 36%. The only deviation from this contraction occurred in 2024, when invested capital rose slightly to 69,263 million US$ before continuing its decline in 2025.
Economic Profit
Economic profit mirrors the trends seen in the spread ratio, moving from positive contributions of 4,843 million US$ in 2021 and 4,670 million US$ in 2022 to significant deficits in 2023 (-2,543 million US$) and 2024 (-1,396 million US$). The transition back to a positive economic profit of 567 million US$ in 2025 marks a return to the generation of wealth above the required minimum return, although the magnitude of this profit is markedly lower than that recorded at the start of the period.

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Economic Profit Margin

AbbVie Inc., economic profit margin calculation, comparison to benchmarks

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Selected Financial Data (US$ in millions)
Economic profit1 567 (1,396) (2,543) 4,670 4,843
Net revenues 61,160 56,334 54,318 58,054 56,197
Performance Ratio
Economic profit margin2 0.93% -2.48% -4.68% 8.04% 8.62%
Benchmarks
Economic Profit Margin, Competitors3
Amgen Inc. 10.67% -0.79% 6.28% 11.14% 11.50%
Bristol-Myers Squibb Co. 7.22% -28.29% 2.63% -1.52% 2.25%
Danaher Corp. -32.92% -33.67% -38.34% -16.57% -14.59%
Eli Lilly & Co. 23.12% 11.70% 1.42% 7.44% 9.60%
Gilead Sciences Inc. 19.00% -15.90% 5.19% -0.12% 12.27%
Johnson & Johnson 17.28% 2.53% 0.31% 6.62% 11.07%
Merck & Co. Inc. 16.19% 16.85% -10.10% 14.35% 16.93%
Pfizer Inc. -7.94% -6.89% -24.33% 19.85% 12.06%
Regeneron Pharmaceuticals Inc. 12.96% 14.78% 12.45% 19.15% 42.45%
Thermo Fisher Scientific Inc. -15.81% -15.85% -17.47% -12.91% -10.13%
Vertex Pharmaceuticals Inc. 18.58% -18.54% 15.25% 20.83% 18.99%

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 Economic profit. See details »

2 2025 Calculation
Economic profit margin = 100 × Economic profit ÷ Net revenues
= 100 × 567 ÷ 61,160 = 0.93%

3 Click competitor name to see calculations.


The financial trajectory from 2021 to 2025 reveals a period of significant volatility in economic value generation. After an initial phase of positive value creation, the company experienced a substantial downturn characterized by two consecutive years of economic loss before returning to a positive, albeit lower, state in 2025.

Net Revenue Performance
Revenues exhibited fluctuations over the period, increasing from US$ 56,197 million in 2021 to US$ 58,054 million in 2022. A contraction occurred in 2023, with revenues falling to US$ 54,318 million, followed by a steady recovery that culminated in a five-year peak of US$ 61,160 million by December 31, 2025.
Economic Profit Trends
A sharp decline in economic profit is observed, dropping from US$ 4,843 million in 2021 to a deficit of US$ 2,543 million in 2023. This period of value destruction continued into 2024, although the loss narrowed to US$ 1,396 million. A return to positive economic profit was achieved in 2025, with a recorded value of US$ 567 million.
Economic Profit Margin Analysis
The economic profit margin closely mirrors the trend of absolute economic profit. Starting at 8.62% in 2021, the margin contracted to 8.04% in 2022 before plunging to -4.68% in 2023. The subsequent recovery to -2.48% in 2024 and 0.93% in 2025 indicates a gradual restoration of the company's capacity to generate returns in excess of its cost of capital, although the margin remains significantly below 2021 and 2022 levels.

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