Analysis of Profitability Ratios
Quarterly Data
Profitability ratios measure the company ability to generate profitable sales from its resources (assets).
Profitability Ratios (Summary)
Merck & Co. Inc., profitability ratios (quarterly data)
Based on: 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31).
- Gross Profit Margin
- The gross profit margin showed a generally increasing trend from the first available quarter (March 31, 2020) through March 31, 2025. Starting around 67.74%, it exhibited steady improvement, reaching 76.42% by March 31, 2025. This indicates enhanced efficiency in managing production costs relative to revenue over the observed periods.
- Operating Profit Margin
- The operating profit margin experienced notable fluctuations during the period. Initially around 16.47% in March 31, 2020, it declined to as low as 10.34% by September 30, 2021, before improving sharply to peak at 33.04% in September 30, 2022. Subsequently, considerable volatility continued, with a decline to a low of 3.92% in March 31, 2023, followed by recovery and another peak at 31.51% by March 31, 2025. These variations suggest periods of both operational challenges and strong operational efficiency.
- Net Profit Margin
- The net profit margin similarly displayed volatility but with an overall upward tendency. After starting near 14.72% in March 31, 2020, it rose significantly, peaking at 29.00% around September 30, 2022. However, it fell again to as low as 0.61% by September 30, 2023, before rebounding to 27.27% by the end of the timeline. These swings may reflect varying non-operational influences and profitability pressures beyond core operations.
- Return on Equity (ROE)
- The ROE showed marked fluctuations, with an initial value of 27.91%, rising to a peak of 38.34% in September 30, 2022. This was followed by a sharp decline to under 1% in September 30, 2023, and a strong recovery back to over 36% by March 31, 2025. The pattern demonstrates periods of significant profitability gains for shareholders, interrupted by temporary declines possibly due to extraordinary factors or changes in net income or equity base.
- Return on Assets (ROA)
- The ROA mirrored the trends seen in ROE and profit margins, beginning around 7.72% and gradually increasing to 15.48% by September 30, 2022. This was followed by a sharp contraction to approximately 0.34% in the same period when other profitability ratios dipped, then a recovery to 15.14% by the end of the period. This indicates effective utilization of assets over time but with some intermittent challenges impacting asset profitability.
- Overall Analysis
- The data reveals an improving gross profit margin indicating cost control improvements. However, operating and net profit margins, along with ROE and ROA, displayed significant variability, including sharp declines and quick recoveries within short spans. These fluctuations may be attributed to transient operational issues, market conditions, or exceptional items affecting profitability and returns. The strong recoveries toward the end of the period suggest resilience and a potential return to higher profitability and efficiency levels going forward.
Return on Sales
Return on Investment
Gross Profit Margin
Merck & Co. Inc., gross profit margin calculation (quarterly data)
| Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | Dec 31, 2020 | Sep 30, 2020 | Jun 30, 2020 | Mar 31, 2020 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||||||
| Gross profit | 12,110) | 11,796) | 12,577) | 12,367) | 12,235) | 10,719) | 11,698) | 11,011) | 10,561) | 9,949) | 11,025) | 10,377) | 10,521) | 9,648) | 9,704) | 8,298) | 7,428) | 6,981) | 9,070) | 7,713) | 8,745) | |||||||
| Sales | 15,529) | 15,624) | 16,657) | 16,112) | 15,775) | 14,631) | 15,962) | 15,035) | 14,487) | 13,830) | 14,959) | 14,593) | 15,901) | 13,521) | 13,154) | 11,402) | 10,627) | 12,514) | 12,551) | 10,872) | 12,057) | |||||||
| Profitability Ratio | ||||||||||||||||||||||||||||
| Gross profit margin1 | 76.42% | 76.32% | 75.82% | 75.25% | 74.37% | 73.17% | 72.86% | 72.96% | 72.43% | 70.63% | 70.49% | 70.41% | 70.72% | 72.02% | 67.95% | 67.48% | 66.99% | 67.74% | — | — | — | |||||||
| Benchmarks | ||||||||||||||||||||||||||||
| Gross Profit Margin, Competitors2 | ||||||||||||||||||||||||||||
| AbbVie Inc. | 70.69% | 69.99% | 67.21% | 62.75% | 62.28% | 62.42% | 65.76% | 68.91% | 69.43% | 70.00% | 69.62% | 70.48% | 69.53% | 68.96% | 67.72% | 65.62% | 64.82% | 66.41% | — | — | — | |||||||
| Amgen Inc. | 61.48% | 59.85% | 58.71% | 61.56% | 64.76% | 68.60% | 72.35% | 72.87% | 73.65% | 74.17% | 73.99% | 74.00% | 73.30% | 73.44% | 74.00% | 73.97% | 74.37% | 74.59% | — | — | — | |||||||
| Bristol-Myers Squibb Co. | 70.47% | 71.08% | 74.91% | 75.38% | 75.71% | 76.24% | 76.54% | 77.01% | 77.68% | 78.04% | 78.82% | 79.13% | 79.62% | 78.57% | 76.92% | 75.88% | 74.42% | 72.31% | — | — | — | |||||||
| Danaher Corp. | 59.74% | 59.50% | 59.37% | 59.27% | 58.39% | 58.74% | 58.77% | 59.17% | 60.22% | 60.21% | 60.65% | 60.77% | 60.77% | 60.95% | 60.44% | 59.24% | 57.60% | 55.98% | — | — | — | |||||||
| Eli Lilly & Co. | 81.70% | 81.31% | 80.91% | 80.75% | 80.16% | 79.25% | 78.67% | 77.77% | 77.67% | 76.77% | 75.61% | 75.98% | 74.40% | 74.18% | 74.85% | 74.27% | 75.88% | 77.66% | — | — | — | |||||||
| Gilead Sciences Inc. | 78.17% | 78.15% | 75.98% | 75.56% | 75.62% | 75.87% | 78.66% | 79.27% | 78.94% | 79.03% | 74.31% | 75.30% | 75.50% | 75.56% | 80.23% | 79.90% | 80.32% | 81.23% | — | — | — | |||||||
| Johnson & Johnson | 68.30% | 69.07% | 69.05% | 69.06% | 69.20% | 68.82% | 68.54% | 68.06% | 67.34% | 67.26% | 67.43% | 67.86% | 67.97% | 68.16% | 67.51% | 67.00% | 66.24% | 65.58% | — | — | — | |||||||
| Pfizer Inc. | 72.28% | 71.94% | 67.73% | 58.18% | 58.09% | 58.10% | 60.97% | 69.61% | 68.61% | 65.77% | 65.53% | 62.18% | 60.35% | 62.08% | 65.28% | 70.96% | 76.46% | 79.26% | — | — | — | |||||||
| Regeneron Pharmaceuticals Inc. | 85.79% | 86.13% | 86.12% | 86.16% | 86.32% | 86.16% | 85.96% | 86.42% | 86.96% | 87.18% | 85.39% | 84.97% | 84.65% | 84.83% | 86.65% | 86.85% | 86.84% | 86.82% | — | — | — | |||||||
| Thermo Fisher Scientific Inc. | 41.34% | 41.28% | 40.77% | 40.76% | 40.40% | 39.90% | 39.87% | 39.75% | 40.28% | 42.24% | 44.42% | 46.63% | 48.37% | 50.08% | 51.05% | 51.29% | 51.47% | 49.67% | — | — | — | |||||||
| Vertex Pharmaceuticals Inc. | 86.03% | 86.11% | 86.12% | 86.45% | 86.86% | 87.21% | 87.80% | 87.92% | 88.04% | 87.90% | 88.00% | 88.13% | 87.95% | 88.06% | 87.94% | 87.89% | 88.06% | 88.14% | — | — | — | |||||||
Based on: 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31).
1 Q1 2025 Calculation
Gross profit margin = 100
× (Gross profitQ1 2025
+ Gross profitQ4 2024
+ Gross profitQ3 2024
+ Gross profitQ2 2024)
÷ (SalesQ1 2025
+ SalesQ4 2024
+ SalesQ3 2024
+ SalesQ2 2024)
= 100 × (12,110 + 11,796 + 12,577 + 12,367)
÷ (15,529 + 15,624 + 16,657 + 16,112)
= 76.42%
2 Click competitor name to see calculations.
The quarterly financial data reveals several notable trends in profitability and sales performance over the analyzed periods.
- Gross Profit
- The gross profit experienced fluctuations throughout the periods but generally demonstrated an upward trend. Initial values in early 2020 showed some volatility, with a low point of 6,981 million USD in December 2020, followed by recovery and growth. From March 2021 onward, gross profit mostly increased, reaching peaks above 12,000 million USD in mid-2024. Despite some quarter-to-quarter variability, the overall direction indicates improving gross profitability over the long term.
- Sales
- Sales figures displayed noticeable growth across the periods, starting from about 10,627 million USD in March 2021 to a peak exceeding 16,600 million USD by late 2024. Early 2020 figures showed moderate sales with fluctuations, but from 2021 onward, sales surged significantly. A slight dip is observed in the most recent quarter at approximately 15,529 million USD, yet the overall sales trend is upwards, indicating expanding market reach or volume.
- Gross Profit Margin
- The gross profit margin improved steadily over the surveyed quarters. Starting near 67.7% in early 2020, the margin gradually increased each quarter, surpassing 70% in mid-2021 and steadily climbing to over 76% by early 2025. This positive trend suggests enhanced cost efficiency, better pricing strategies, or favorable product mix impacting profitability margins positively. The margin's consistent rise alongside sales growth reinforces the company’s strengthening profitability position.
In summary, the company exhibited solid financial performance improvements in recent years. Both gross profit and sales showed upward momentum with gross profit increasing at a rate that outpaces sales growth, as reflected in the expanding gross profit margin. The trends indicate effective management of production costs and revenues, positioning the company well for sustained profitability advancement.
Operating Profit Margin
Merck & Co. Inc., operating profit margin calculation (quarterly data)
| Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | Dec 31, 2020 | Sep 30, 2020 | Jun 30, 2020 | Mar 31, 2020 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||||||
| Operating income (loss) | 5,868) | 4,299) | 3,928) | 6,048) | 5,637) | (1,967) | 5,746) | (5,163) | 3,739) | 3,439) | 4,012) | 4,925) | 5,569) | 3,576) | 4,816) | 1,614) | 2,532) | (2,249) | 3,116) | 3,129) | 3,909) | |||||||
| Sales | 15,529) | 15,624) | 16,657) | 16,112) | 15,775) | 14,631) | 15,962) | 15,035) | 14,487) | 13,830) | 14,959) | 14,593) | 15,901) | 13,521) | 13,154) | 11,402) | 10,627) | 12,514) | 12,551) | 10,872) | 12,057) | |||||||
| Profitability Ratio | ||||||||||||||||||||||||||||
| Operating profit margin1 | 31.51% | 31.03% | 21.60% | 24.75% | 6.93% | 3.92% | 13.08% | 10.34% | 27.85% | 30.27% | 30.66% | 33.04% | 28.85% | 25.74% | 14.07% | 10.64% | 14.02% | 16.47% | — | — | — | |||||||
| Benchmarks | ||||||||||||||||||||||||||||
| Operating Profit Margin, Competitors2 | ||||||||||||||||||||||||||||
| AbbVie Inc. | 17.56% | 16.22% | 24.89% | 22.31% | 23.50% | 23.49% | 27.32% | 31.03% | 28.49% | 31.21% | 30.59% | 30.33% | 32.68% | 31.89% | 30.09% | 28.95% | 23.63% | 24.81% | — | — | — | |||||||
| Amgen Inc. | 22.71% | 22.66% | 19.97% | 20.96% | 24.72% | 29.35% | 34.55% | 37.50% | 36.07% | 38.57% | 39.31% | 38.04% | 32.78% | 31.44% | 30.14% | 30.72% | 37.23% | 37.70% | — | — | — | |||||||
| Bristol-Myers Squibb Co. | 15.24% | -15.50% | -14.05% | -14.39% | -14.30% | 16.18% | 16.96% | 17.29% | 18.13% | 17.96% | 19.04% | 18.19% | 16.79% | 15.91% | -15.73% | -17.02% | -19.19% | -21.60% | — | — | — | |||||||
| Danaher Corp. | 20.26% | 20.37% | 20.11% | 21.22% | 21.05% | 21.77% | 23.83% | 25.06% | 27.02% | 27.61% | 27.35% | 25.44% | 25.23% | 25.35% | 24.63% | 25.04% | 22.30% | 18.99% | — | — | — | |||||||
| Eli Lilly & Co. | 28.74% | 28.64% | 24.81% | 23.28% | 20.80% | 18.92% | 18.42% | 24.17% | 22.45% | 24.97% | 24.65% | 25.50% | 25.94% | 22.45% | 23.17% | 21.81% | 22.06% | 24.69% | — | — | — | |||||||
| Gilead Sciences Inc. | 28.77% | 5.81% | 2.92% | 9.26% | 5.79% | 28.24% | 30.37% | 31.18% | 33.03% | 27.17% | 22.39% | 25.78% | 26.56% | 36.72% | 42.79% | 37.20% | 18.07% | 16.72% | — | — | — | |||||||
| Johnson & Johnson | 23.59% | 23.42% | 24.42% | 25.31% | 25.04% | 24.90% | 25.55% | 25.61% | 25.21% | 24.63% | 23.89% | 23.47% | 23.76% | 24.95% | 24.69% | 25.23% | 24.10% | 23.60% | — | — | — | |||||||
| Pfizer Inc. | 19.29% | 19.51% | 9.56% | -4.19% | -2.08% | 2.15% | 14.36% | 28.13% | 34.44% | 34.83% | 33.59% | 30.37% | 26.12% | 23.91% | 24.67% | 24.12% | 21.20% | 19.47% | — | — | — | |||||||
| Regeneron Pharmaceuticals Inc. | 27.20% | 28.10% | 28.69% | 28.95% | 29.40% | 30.85% | 32.23% | 34.20% | 35.79% | 38.93% | 45.45% | 48.19% | 55.08% | 55.67% | 55.19% | 53.94% | 43.37% | 42.09% | — | — | — | |||||||
| Thermo Fisher Scientific Inc. | 17.23% | 17.11% | 16.93% | 17.01% | 16.38% | 16.00% | 15.81% | 15.42% | 16.29% | 18.69% | 20.54% | 22.51% | 23.83% | 25.57% | 27.04% | 28.00% | 27.68% | 24.19% | — | — | — | |||||||
| Vertex Pharmaceuticals Inc. | -6.69% | -2.11% | -2.54% | -3.37% | 41.16% | 38.83% | 40.16% | 41.72% | 43.93% | 48.23% | 47.72% | 48.85% | 36.93% | 36.73% | 37.17% | 33.93% | 47.14% | 46.03% | — | — | — | |||||||
Based on: 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31).
1 Q1 2025 Calculation
Operating profit margin = 100
× (Operating income (loss)Q1 2025
+ Operating income (loss)Q4 2024
+ Operating income (loss)Q3 2024
+ Operating income (loss)Q2 2024)
÷ (SalesQ1 2025
+ SalesQ4 2024
+ SalesQ3 2024
+ SalesQ2 2024)
= 100 × (5,868 + 4,299 + 3,928 + 6,048)
÷ (15,529 + 15,624 + 16,657 + 16,112)
= 31.51%
2 Click competitor name to see calculations.
- Operating Income (Loss)
- The operating income shows a volatile pattern across the periods. Starting at 3,909 million USD in March 2020, it declined slightly through June and September 2020, followed by a significant loss of 2,249 million USD in December 2020. Recovery occurred in 2021 with fluctuations, peaking at 4,816 million USD in September 2021 before declining again in subsequent quarters. The most notable loss was observed in June 2023 with -5,163 million USD, followed by recovery and volatility through 2024. Overall, the operating income demonstrates irregular fluctuations with periods of both strong profitability and considerable losses.
- Sales
- Sales figures have generally shown an upward trend from 12,057 million USD in March 2020, rising with some variability and reaching peaks above 16,000 million USD, notably in March and September 2024. There are intervals of slight decline, particularly around early 2025, but the overall pattern suggests growth in sales revenue over the observed periods. The data indicates some seasonal or cyclical variation though growth remains evident.
- Operating Profit Margin
- The operating profit margin, expressed as a percentage, was unavailable for the initial periods but became positive and stable from December 2020 onward. Margins fluctuated between approximately 10% and more than 33%, with the highest margin seen in September 2022 (33.04%). Margins declined significantly in mid-2023, aligning with the negative operating income, before rebounding again by the end of 2024, reaching approximately 31.5%. This pattern suggests episodic profitability struggles, but generally, the company managed to maintain a healthy margin over the longer term.
- Summary Insights
- The company's performance exhibits cyclical and volatile characteristics. Sales consistently trend upward overall, indicating strong market demand or successful revenue generation strategies. However, operating income and profit margin reflect considerable variability, including some sharp declines linked to specific quarters reflecting operational challenges or unusual expenses. The disconnect between rising sales and fluctuating profitability suggests factors influencing cost control, expenses, or one-time charges affecting operating income. Maintaining margin stability remains a challenge, with periods of recovery indicating responsive management actions. Continued attention to operational efficiency is implied to sustain profitability alongside revenue growth.
Net Profit Margin
Merck & Co. Inc., net profit margin calculation (quarterly data)
| Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | Dec 31, 2020 | Sep 30, 2020 | Jun 30, 2020 | Mar 31, 2020 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||||||
| Net income (loss) attributable to Merck & Co., Inc. | 5,079) | 3,743) | 3,157) | 5,455) | 4,762) | (1,226) | 4,745) | (5,975) | 2,821) | 3,017) | 3,248) | 3,944) | 4,310) | 3,758) | 4,567) | 1,545) | 3,179) | (2,095) | 2,941) | 3,002) | 3,219) | |||||||
| Sales | 15,529) | 15,624) | 16,657) | 16,112) | 15,775) | 14,631) | 15,962) | 15,035) | 14,487) | 13,830) | 14,959) | 14,593) | 15,901) | 13,521) | 13,154) | 11,402) | 10,627) | 12,514) | 12,551) | 10,872) | 12,057) | |||||||
| Profitability Ratio | ||||||||||||||||||||||||||||
| Net profit margin1 | 27.27% | 26.68% | 19.23% | 21.98% | 3.76% | 0.61% | 7.77% | 5.34% | 22.52% | 24.49% | 25.88% | 29.00% | 26.27% | 26.79% | 15.09% | 11.83% | 15.09% | 14.72% | — | — | — | |||||||
| Benchmarks | ||||||||||||||||||||||||||||
| Net Profit Margin, Competitors2 | ||||||||||||||||||||||||||||
| AbbVie Inc. | 7.31% | 7.59% | 9.22% | 9.71% | 11.02% | 8.95% | 11.81% | 15.50% | 13.37% | 20.39% | 23.19% | 22.04% | 22.00% | 20.54% | 13.66% | 12.40% | 10.28% | 10.08% | — | — | — | |||||||
| Amgen Inc. | 18.10% | 12.77% | 13.58% | 10.60% | 13.35% | 24.96% | 29.52% | 31.52% | 31.77% | 26.42% | 27.88% | 26.73% | 23.42% | 24.25% | 23.03% | 23.80% | 29.60% | 29.97% | — | — | — | |||||||
| Bristol-Myers Squibb Co. | 11.38% | -18.53% | -15.30% | -14.06% | -13.50% | 17.83% | 18.44% | 17.62% | 15.95% | 13.71% | 14.29% | 14.04% | 13.31% | 15.08% | -11.89% | -11.44% | -14.53% | -21.20% | — | — | — | |||||||
| Danaher Corp. | 15.81% | 16.33% | 16.39% | 17.83% | 18.54% | 19.94% | 22.89% | 22.80% | 23.32% | 22.91% | 21.65% | 20.61% | 21.32% | 21.84% | 20.97% | 21.00% | 19.17% | 16.36% | — | — | — | |||||||
| Eli Lilly & Co. | 22.66% | 23.51% | 20.48% | 18.86% | 17.08% | 15.36% | 15.55% | 22.01% | 20.54% | 21.88% | 20.63% | 19.58% | 20.90% | 19.71% | 21.52% | 22.71% | 23.91% | 25.24% | — | — | — | |||||||
| Gilead Sciences Inc. | 20.87% | 1.68% | 0.45% | 3.82% | 1.78% | 21.03% | 21.60% | 20.18% | 20.87% | 17.02% | 12.44% | 15.22% | 16.60% | 23.05% | 27.21% | 19.62% | 1.19% | 0.51% | — | — | — | |||||||
| Johnson & Johnson | 24.41% | 15.84% | 16.74% | 43.91% | 44.92% | 41.28% | 39.58% | 14.52% | 13.77% | 18.90% | 19.95% | 19.21% | 20.90% | 22.26% | 19.55% | 19.92% | 17.95% | 17.82% | — | — | — | |||||||
| Pfizer Inc. | 12.62% | 12.62% | 7.04% | -4.62% | -0.55% | 3.56% | 15.13% | 27.38% | 31.19% | 31.27% | 29.81% | 28.94% | 27.01% | 27.04% | 28.77% | 23.86% | 24.03% | 22.95% | — | — | — | |||||||
| Regeneron Pharmaceuticals Inc. | 31.94% | 31.07% | 33.61% | 32.04% | 29.45% | 30.14% | 30.47% | 33.93% | 33.81% | 35.64% | 39.17% | 39.97% | 48.06% | 50.25% | 51.65% | 50.11% | 43.53% | 41.35% | — | — | — | |||||||
| Thermo Fisher Scientific Inc. | 15.18% | 14.77% | 14.48% | 14.69% | 14.20% | 13.99% | 13.68% | 13.14% | 13.75% | 15.47% | 15.92% | 17.37% | 18.49% | 19.70% | 21.93% | 22.47% | 22.08% | 19.79% | — | — | — | |||||||
| Vertex Pharmaceuticals Inc. | -8.91% | -4.86% | -4.52% | -4.74% | 39.46% | 36.68% | 35.94% | 35.40% | 35.40% | 37.20% | 37.62% | 38.26% | 30.84% | 30.92% | 30.52% | 29.80% | 43.06% | 43.70% | — | — | — | |||||||
Based on: 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31).
1 Q1 2025 Calculation
Net profit margin = 100
× (Net income (loss) attributable to Merck & Co., Inc.Q1 2025
+ Net income (loss) attributable to Merck & Co., Inc.Q4 2024
+ Net income (loss) attributable to Merck & Co., Inc.Q3 2024
+ Net income (loss) attributable to Merck & Co., Inc.Q2 2024)
÷ (SalesQ1 2025
+ SalesQ4 2024
+ SalesQ3 2024
+ SalesQ2 2024)
= 100 × (5,079 + 3,743 + 3,157 + 5,455)
÷ (15,529 + 15,624 + 16,657 + 16,112)
= 27.27%
2 Click competitor name to see calculations.
Analysis of the quarterly financial data reveals varying trends in net income, sales, and net profit margins over the observed periods.
- Net Income (Loss) Attributable to the Company (US$ in millions)
- The net income figures exhibit considerable volatility throughout the quarters. Starting at 3,219 million in March 2020, net income experienced fluctuations with some notable declines, particularly in December 2020 and June 2023, where losses were recorded (-2,095 million and -5,975 million respectively). Following these periods, the company demonstrated recovery with positive net incomes again, notably reaching 5,455 million in June 2024. The trend indicates periods of significant earnings volatility, with some quarters showing strong profitability and others considerable losses.
- Sales (US$ in millions)
- Sales generally show an upward trend over the quarters, though with some fluctuations. Beginning at 12,057 million in March 2020, sales dipped slightly in mid-2020 but rose substantially peaking at 16,657 million in September 2024. Despite some decreases in sales during the final quarters of 2024 and early 2025, overall sales figures suggest steady growth in revenue generation over the observed timeline.
- Net Profit Margin (%)
- Net profit margins display significant variation corresponding to the fluctuations in net income and sales. Margins ranged from low levels near 0.61% in December 2023 to highs above 29% in September 2022. The periods with negative net income coincide with markedly lower profit margins, while quarters with strong net income deliver more robust margins exceeding 20%. The variability suggests sensitivity of profitability to changes in operational performance and possibly extraordinary items affecting net income.
Return on Equity (ROE)
Merck & Co. Inc., ROE calculation (quarterly data)
| Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | Dec 31, 2020 | Sep 30, 2020 | Jun 30, 2020 | Mar 31, 2020 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||||||
| Net income (loss) attributable to Merck & Co., Inc. | 5,079) | 3,743) | 3,157) | 5,455) | 4,762) | (1,226) | 4,745) | (5,975) | 2,821) | 3,017) | 3,248) | 3,944) | 4,310) | 3,758) | 4,567) | 1,545) | 3,179) | (2,095) | 2,941) | 3,002) | 3,219) | |||||||
| Total Merck & Co., Inc. stockholders’ equity | 48,335) | 46,313) | 44,502) | 43,582) | 40,364) | 37,581) | 41,246) | 38,693) | 46,834) | 45,991) | 44,458) | 43,243) | 40,883) | 38,184) | 35,794) | 33,294) | 26,945) | 25,317) | 29,186) | 27,642) | 26,205) | |||||||
| Profitability Ratio | ||||||||||||||||||||||||||||
| ROE1 | 36.07% | 36.96% | 27.30% | 31.52% | 5.71% | 0.97% | 11.17% | 8.04% | 27.82% | 31.57% | 34.32% | 38.34% | 34.68% | 34.17% | 20.10% | 16.73% | 26.08% | 27.91% | — | — | — | |||||||
| Benchmarks | ||||||||||||||||||||||||||||
| ROE, Competitors2 | ||||||||||||||||||||||||||||
| AbbVie Inc. | 295.42% | 128.66% | 84.91% | 78.77% | 74.85% | 46.94% | 53.86% | 67.50% | 57.14% | 68.60% | 83.83% | 86.24% | 76.64% | 74.91% | 55.60% | 53.01% | 37.63% | 35.30% | — | — | — | |||||||
| Amgen Inc. | 95.59% | 69.59% | 56.20% | 52.83% | 74.93% | 107.78% | 98.82% | 117.67% | 148.04% | 178.97% | 187.11% | 271.85% | 624.78% | 87.96% | 68.26% | 69.67% | 75.91% | 77.20% | — | — | — | |||||||
| Bristol-Myers Squibb Co. | 31.16% | -54.78% | -42.34% | -38.44% | -37.28% | 27.27% | 28.57% | 24.91% | 22.97% | 20.37% | 20.44% | 20.30% | 19.79% | 19.46% | -14.52% | -13.80% | -16.54% | -23.84% | — | — | — | |||||||
| Danaher Corp. | 7.40% | 7.87% | 7.59% | 8.42% | 8.24% | 8.91% | 11.29% | 12.30% | 13.47% | 14.39% | 14.40% | 13.63% | 13.93% | 14.24% | 13.54% | 13.12% | 11.76% | 9.17% | — | — | — | |||||||
| Eli Lilly & Co. | 70.45% | 74.62% | 58.78% | 54.14% | 47.91% | 48.65% | 44.46% | 58.73% | 50.82% | 58.64% | 59.91% | 66.61% | 65.69% | 62.16% | 76.99% | 94.20% | 88.31% | 109.79% | — | — | — | |||||||
| Gilead Sciences Inc. | 31.13% | 2.48% | 0.69% | 5.77% | 2.77% | 24.81% | 26.33% | 25.92% | 26.59% | 21.62% | 15.82% | 20.44% | 22.66% | 29.55% | 34.44% | 26.20% | 1.59% | 0.68% | — | — | — | |||||||
| Johnson & Johnson | 27.92% | 19.68% | 20.93% | 53.14% | 54.95% | 51.11% | 48.61% | 17.37% | 17.95% | 23.36% | 25.68% | 24.05% | 26.54% | 28.20% | 25.44% | 25.53% | 22.96% | 23.25% | — | — | — | |||||||
| Pfizer Inc. | 8.73% | 9.11% | 4.61% | -2.96% | -0.33% | 2.38% | 10.81% | 21.68% | 28.77% | 32.79% | 32.14% | 33.61% | 30.29% | 28.47% | 26.28% | 18.86% | 16.23% | 15.21% | — | — | — | |||||||
| Regeneron Pharmaceuticals Inc. | 15.31% | 15.03% | 15.87% | 15.32% | 14.29% | 15.22% | 16.03% | 17.90% | 17.80% | 19.14% | 25.05% | 27.49% | 39.84% | 43.03% | 40.53% | 41.02% | 33.43% | 31.86% | — | — | — | |||||||
| Thermo Fisher Scientific Inc. | 13.19% | 12.78% | 12.52% | 13.12% | 13.26% | 12.83% | 13.11% | 13.08% | 14.26% | 15.80% | 16.15% | 17.59% | 18.56% | 18.94% | 22.13% | 23.32% | 22.60% | 18.47% | — | — | — | |||||||
| Vertex Pharmaceuticals Inc. | -5.99% | -3.26% | -3.07% | -3.32% | 21.67% | 20.59% | 21.01% | 21.75% | 22.59% | 23.88% | 25.12% | 26.77% | 22.47% | 23.19% | 22.83% | 21.66% | 30.76% | 31.22% | — | — | — | |||||||
Based on: 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31).
1 Q1 2025 Calculation
ROE = 100
× (Net income (loss) attributable to Merck & Co., Inc.Q1 2025
+ Net income (loss) attributable to Merck & Co., Inc.Q4 2024
+ Net income (loss) attributable to Merck & Co., Inc.Q3 2024
+ Net income (loss) attributable to Merck & Co., Inc.Q2 2024)
÷ Total Merck & Co., Inc. stockholders’ equity
= 100 × (5,079 + 3,743 + 3,157 + 5,455)
÷ 48,335 = 36.07%
2 Click competitor name to see calculations.
The data reflects varying trends in key financial indicators over several quarters.
- Net Income
- Net income has exhibited significant fluctuations throughout the periods. Initially, positive net income values were observed, followed by a sharp loss in late 2020. Subsequent quarters saw a recovery with mostly positive values, although there are intermittent quarters with notable declines or losses, such as the substantial drop in mid-2023. Overall, the net income demonstrates volatility with episodes of both strong profitability and marked losses.
- Total Stockholders’ Equity
- Total stockholders’ equity shows a general upward trend over the majority of the timeline. Despite some declines, particularly around the end of 2020 and mid-2023, equity balances have increased steadily from the early periods into the latest quarters. This suggests accumulation of retained earnings or capital infusions over time, contributing to a strengthening equity base.
- Return on Equity (ROE)
- ROE values are absent for the initial periods but start appearing in 2021, reflecting strong returns initially exceeding 20% and peaking around 38%. Nonetheless, there is a period of decline around 2023 with ROE dropping sharply to single digits and near 1%, indicating reduced profitability relative to equity during that phase. Towards the end of the reported period, ROE recovers robustly, returning to levels above 30%, signaling improved efficiency in generating earnings from equity.
The overall analysis indicates a company experiencing cyclical financial performance with intermittent challenges affecting net income and return measures. Equity growth remains a positive underlying trend, while profitability metrics demonstrate sensitivity to operational or market conditions reflected in the quarterly results.
Return on Assets (ROA)
Merck & Co. Inc., ROA calculation (quarterly data)
| Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | Dec 31, 2020 | Sep 30, 2020 | Jun 30, 2020 | Mar 31, 2020 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||||||
| Net income (loss) attributable to Merck & Co., Inc. | 5,079) | 3,743) | 3,157) | 5,455) | 4,762) | (1,226) | 4,745) | (5,975) | 2,821) | 3,017) | 3,248) | 3,944) | 4,310) | 3,758) | 4,567) | 1,545) | 3,179) | (2,095) | 2,941) | 3,002) | 3,219) | |||||||
| Total assets | 115,122) | 117,106) | 117,532) | 112,630) | 105,849) | 106,675) | 106,727) | 104,469) | 107,796) | 109,160) | 107,081) | 107,095) | 106,668) | 105,694) | 93,494) | 90,688) | 90,847) | 91,588) | 89,800) | 90,615) | 84,913) | |||||||
| Profitability Ratio | ||||||||||||||||||||||||||||
| ROA1 | 15.14% | 14.62% | 10.34% | 12.20% | 2.18% | 0.34% | 4.32% | 2.98% | 12.09% | 13.30% | 14.25% | 15.48% | 13.29% | 12.35% | 7.70% | 6.14% | 7.73% | 7.72% | — | — | — | |||||||
| Benchmarks | ||||||||||||||||||||||||||||
| ROA, Competitors2 | ||||||||||||||||||||||||||||
| AbbVie Inc. | 3.08% | 3.17% | 3.57% | 3.76% | 4.03% | 3.61% | 4.78% | 6.42% | 5.64% | 8.53% | 9.49% | 8.83% | 8.71% | 7.88% | 5.06% | 4.50% | 3.43% | 3.07% | — | — | — | |||||||
| Amgen Inc. | 6.64% | 4.45% | 4.65% | 3.44% | 4.05% | 6.91% | 8.36% | 8.84% | 8.92% | 10.06% | 10.73% | 11.09% | 9.67% | 9.63% | 8.63% | 9.61% | 11.33% | 11.54% | — | — | — | |||||||
| Bristol-Myers Squibb Co. | 5.86% | -9.66% | -7.75% | -6.91% | -6.21% | 8.43% | 9.08% | 8.52% | 7.75% | 6.53% | 6.80% | 6.59% | 6.07% | 6.40% | -4.87% | -4.58% | -5.53% | -7.61% | — | — | — | |||||||
| Danaher Corp. | 4.76% | 5.03% | 4.83% | 5.35% | 5.28% | 5.64% | 6.74% | 7.49% | 8.15% | 8.55% | 8.35% | 7.76% | 7.74% | 7.73% | 7.13% | 7.19% | 6.30% | 4.79% | — | — | — | |||||||
| Eli Lilly & Co. | 12.42% | 13.45% | 11.07% | 10.22% | 9.60% | 8.19% | 8.61% | 11.85% | 10.70% | 12.62% | 12.71% | 12.09% | 13.06% | 11.44% | 12.39% | 12.70% | 13.01% | 13.28% | — | — | — | |||||||
| Gilead Sciences Inc. | 10.57% | 0.81% | 0.23% | 1.97% | 0.86% | 9.12% | 9.42% | 8.80% | 9.02% | 7.27% | 5.33% | 6.58% | 7.16% | 9.16% | 11.02% | 7.59% | 0.45% | 0.18% | — | — | — | |||||||
| Johnson & Johnson | 11.26% | 7.81% | 8.24% | 20.99% | 22.37% | 20.98% | 20.85% | 6.81% | 6.49% | 9.57% | 10.94% | 10.33% | 11.12% | 11.47% | 9.98% | 10.07% | 8.76% | 8.41% | — | — | — | |||||||
| Pfizer Inc. | 3.79% | 3.76% | 1.94% | -1.20% | -0.14% | 0.94% | 4.87% | 9.75% | 14.85% | 15.91% | 15.32% | 15.01% | 13.58% | 12.11% | 11.10% | 7.78% | 7.01% | 6.23% | — | — | — | |||||||
| Regeneron Pharmaceuticals Inc. | 11.98% | 11.69% | 12.43% | 11.98% | 11.22% | 11.95% | 12.41% | 14.02% | 13.91% | 14.85% | 19.40% | 20.90% | 30.11% | 31.75% | 29.55% | 28.88% | 22.53% | 20.47% | — | — | — | |||||||
| Thermo Fisher Scientific Inc. | 6.58% | 6.51% | 6.11% | 6.32% | 6.21% | 6.07% | 6.12% | 6.08% | 6.36% | 7.15% | 7.77% | 8.21% | 8.20% | 8.12% | 11.64% | 12.70% | 12.02% | 9.23% | — | — | — | |||||||
| Vertex Pharmaceuticals Inc. | -4.32% | -2.38% | -2.16% | -2.43% | 16.81% | 15.92% | 15.97% | 16.54% | 17.18% | 18.30% | 19.59% | 20.50% | 17.19% | 17.44% | 17.25% | 16.30% | 22.80% | 23.07% | — | — | — | |||||||
Based on: 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31).
1 Q1 2025 Calculation
ROA = 100
× (Net income (loss) attributable to Merck & Co., Inc.Q1 2025
+ Net income (loss) attributable to Merck & Co., Inc.Q4 2024
+ Net income (loss) attributable to Merck & Co., Inc.Q3 2024
+ Net income (loss) attributable to Merck & Co., Inc.Q2 2024)
÷ Total assets
= 100 × (5,079 + 3,743 + 3,157 + 5,455)
÷ 115,122 = 15.14%
2 Click competitor name to see calculations.
- Net Income (Loss) Attributable to Merck & Co., Inc.
- The net income figures demonstrate noticeable volatility across the observed periods. Initially, the company reports positive net income values ranging from approximately 2.9 billion to 3.2 billion USD in early 2020. However, a significant negative net income of -2.1 billion USD appears in the last quarter of 2020, indicating a substantial adverse event or extraordinary expense during that time. After this downturn, net income recovers sharply in 2021, with a peak of 4.6 billion USD reported in the third quarter. The subsequent quarters reveal fluctuations, including another negative net income near -6 billion USD at mid-2023. The company then recovers again with net income levels mostly above 3 billion USD from late 2023 through early 2025, culminating in a peak near 5.1 billion USD in the final quarter of 2024.
- Total Assets
- Total assets display a general upward trend from 84.9 billion USD in the first quarter of 2020 to above 117 billion USD by the third quarter of 2024, with some variability. The period between late 2020 and early 2021 shows a notable increase, particularly at year-end 2021, where assets rise sharply to over 105 billion USD from approximately 93 billion USD in the previous quarter. A slight decline in total assets occurs mid-2023 followed by a rebound, maintaining asset levels safely above 105 billion USD in most subsequent periods. The overall trend suggests stable asset growth with some short-term fluctuations.
- Return on Assets (ROA)
- ROA values are available for select periods and show considerable variation. In 2020, ROA fluctuates around 7 to 8%, indicating moderate efficiency in asset utilization. This ratio improves significantly in 2022, peaking near 15.5%, signaling enhanced profitability relative to asset base. However, 2023 introduces volatility, with ROA dropping sharply to around 3% and even below 1% in some quarters, coinciding with periods of negative net income. A recovery trend emerges toward late 2023 and into 2024, where ROA climbs again to double-digit percentages, reaching over 15% by the end of 2024. These shifts reflect the company’s fluctuating profitability against its asset base over time.