Analysis of Profitability Ratios
Quarterly Data
Profitability ratios measure the company ability to generate profitable sales from its resources (assets).
Profitability Ratios (Summary)
Thermo Fisher Scientific Inc., profitability ratios (quarterly data)
Based on: 10-Q (reporting date: 2026-06-27), 10-Q (reporting date: 2026-03-28), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).
A comprehensive analysis of the profitability ratios reveals a distinct pattern of significant contraction followed by a period of stabilization and gradual recovery. Between April 2022 and July 2023, all primary profitability metrics experienced a sharp decline, after which the company entered a phase of marginal improvement and plateauing through mid-2026.
- Margin Performance
- Gross profit margin exhibited a substantial decrease from a peak of 48.37% in April 2022 to a trough of 39.75% in July 2023. Subsequent to this low, the margin recovered modestly and remained relatively stable, fluctuating between 40.40% and 41.34% from March 2024 through June 2026.
- Operating profit margin followed a similar trajectory, falling from 23.83% in April 2022 to 15.42% in July 2023. A consistent upward trend is observable from late 2023 onward, with the ratio reaching 17.58% by June 2026, indicating a gradual recovery in operational efficiency.
- Net profit margin mirrored these movements, declining from 18.49% in early 2022 to 13.14% in July 2023. The metric then stabilized, maintaining a range between 14.20% and 15.23% throughout the latter half of the observed period.
- Return Metrics
- Return on Equity (ROE) showed a persistent downward trend for much of the period, decreasing from 18.56% in April 2022 to a low of 12.52% in September 2024. While a slight recovery to 13.23% was noted by June 2026, the ROE remained significantly below its 2022 levels.
- Return on Assets (ROA) declined from 8.21% in July 2022 to 6.08% in July 2023. For the remainder of the period, ROA remained constrained, fluctuating within a narrow band between 6.05% and 6.58%, suggesting a stagnation in asset productivity relative to the initial period.
- Profitability Synthesis
- The correlation between the decline in gross margins and the subsequent drop in operating and net margins suggests that the initial profitability compression was driven primarily by cost of goods sold or pricing pressures. The stabilization observed from 2024 through 2026 indicates that the company successfully arrested the decline and established a new, lower baseline for its profitability ratios.
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Return on Sales
Return on Investment
Gross Profit Margin
Thermo Fisher Scientific Inc., gross profit margin calculation (quarterly data)
| Jun 27, 2026 | Mar 28, 2026 | Dec 31, 2025 | Sep 27, 2025 | Jun 28, 2025 | Mar 29, 2025 | Dec 31, 2024 | Sep 28, 2024 | Jun 29, 2024 | Mar 30, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jul 1, 2023 | Apr 1, 2023 | Dec 31, 2022 | Oct 1, 2022 | Jul 2, 2022 | Apr 2, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Gross profit | 4,882) | 4,430) | 5,011) | 4,583) | 4,409) | 4,235) | 4,822) | 4,328) | 4,347) | 4,205) | 4,393) | 4,316) | 4,251) | 4,140) | 4,606) | 4,302) | 4,599) | 5,464) | ||||||
| Revenues | 11,994) | 11,005) | 12,215) | 11,122) | 10,855) | 10,364) | 11,395) | 10,598) | 10,541) | 10,345) | 10,886) | 10,574) | 10,687) | 10,710) | 11,450) | 10,677) | 10,970) | 11,818) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| Gross profit margin1 | 40.80% | 40.78% | 40.93% | 41.27% | 41.18% | 41.34% | 41.28% | 40.77% | 40.76% | 40.40% | 39.90% | 39.87% | 39.75% | 40.28% | 42.24% | 44.42% | 46.63% | 48.37% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Gross Profit Margin, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 71.48% | 70.68% | 70.24% | 69.74% | 70.93% | 70.69% | 69.99% | 67.21% | 62.75% | 62.28% | 62.42% | 65.76% | 68.91% | 69.43% | 70.00% | 69.62% | 70.48% | 69.53% | ||||||
| Amgen Inc. | 67.97% | 66.72% | 65.75% | 64.71% | 62.99% | 61.48% | 59.85% | 58.71% | 61.56% | 64.76% | 68.60% | 72.35% | 72.87% | 73.65% | 74.17% | 73.99% | 74.00% | 73.30% | ||||||
| Bristol-Myers Squibb Co. | 70.16% | 70.46% | 71.08% | 69.50% | 70.29% | 70.47% | 71.08% | 74.91% | 75.38% | 75.71% | 76.24% | 76.54% | 77.01% | 77.68% | 78.04% | 78.82% | 79.13% | 79.62% | ||||||
| Danaher Corp. | 58.51% | 58.94% | 59.11% | 59.53% | 59.66% | 59.74% | 59.50% | 59.37% | 59.27% | 58.39% | 58.74% | 58.77% | 59.17% | 60.22% | 60.21% | 60.65% | 60.77% | 60.77% | ||||||
| Eli Lilly & Co. | 83.40% | 82.83% | 83.04% | 83.03% | 82.64% | 81.70% | 81.31% | 80.91% | 80.75% | 80.16% | 79.25% | 78.67% | 77.77% | 77.67% | 76.77% | 75.61% | 75.98% | 74.40% | ||||||
| Gilead Sciences Inc. | 79.15% | 79.01% | 78.44% | 78.31% | 78.42% | 78.17% | 78.15% | 75.98% | 75.56% | 75.62% | 75.87% | 78.66% | 79.27% | 78.94% | 79.03% | 74.31% | 75.30% | 75.50% | ||||||
| Johnson & Johnson | 67.91% | 67.82% | 67.88% | 68.08% | 67.92% | 68.30% | 69.07% | 69.05% | 69.06% | 69.20% | 68.82% | 68.54% | 68.06% | 67.34% | 67.26% | 67.43% | 67.86% | 67.97% | ||||||
| Merck & Co. Inc. | 72.97% | 73.91% | 74.80% | 77.18% | 76.60% | 76.42% | 76.32% | 75.82% | 75.25% | 74.37% | 73.17% | 72.86% | 72.96% | 72.43% | 70.63% | 70.49% | 70.41% | 70.72% | ||||||
| Pfizer Inc. | 73.18% | 73.51% | 74.33% | 73.39% | 72.12% | 72.28% | 71.94% | 67.73% | 58.18% | 58.09% | 58.10% | 60.97% | 69.61% | 68.61% | 65.77% | 65.53% | 62.18% | 60.35% | ||||||
| Regeneron Pharmaceuticals Inc. | 84.86% | 84.55% | 85.35% | 85.39% | 85.57% | 85.79% | 86.13% | 86.12% | 86.16% | 86.32% | 86.16% | 85.96% | 86.42% | 86.96% | 87.18% | 85.39% | 84.97% | 84.65% | ||||||
| Vertex Pharmaceuticals Inc. | 86.00% | 86.24% | 86.24% | 86.28% | 86.11% | 86.03% | 86.11% | 86.12% | 86.45% | 86.86% | 87.21% | 87.80% | 87.92% | 88.04% | 87.90% | 88.00% | 88.13% | 87.95% | ||||||
Based on: 10-Q (reporting date: 2026-06-27), 10-Q (reporting date: 2026-03-28), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).
1 Q2 2026 Calculation
Gross profit margin = 100
× (Gross profitQ2 2026
+ Gross profitQ1 2026
+ Gross profitQ4 2025
+ Gross profitQ3 2025)
÷ (RevenuesQ2 2026
+ RevenuesQ1 2026
+ RevenuesQ4 2025
+ RevenuesQ3 2025)
= 100 × (4,882 + 4,430 + 5,011 + 4,583)
÷ (11,994 + 11,005 + 12,215 + 11,122)
= 40.80%
2 Click competitor name to see calculations.
The analysis of profitability indicates a significant transition in gross margin performance over the observed period, characterized by an initial phase of sharp contraction followed by a sustained period of stability.
- Gross Profit Margin Trend
- A marked decline in gross profit margin is evident from April 2022 through July 2023, during which the ratio fell from 48.37% to a low of 39.75%. This represents a contraction of approximately 8.62 percentage points within a 15-month window.
- Following this decline, the margin entered a stabilization phase. From July 2023 through June 2026, the gross profit margin remained consistently within a narrow band between 39.75% and 41.34%, suggesting the establishment of a new operational baseline.
- Revenue and Gross Profit Correlation
- Revenues experienced a period of volatility and moderate decline between 2022 and early 2024, dropping from 11.8 billion USD to a low of 10.3 billion USD in March 2024. During this interval, gross profit decreased from 5.4 billion USD to 4.2 billion USD, reflecting the combined impact of reduced sales volume and compressed margins.
- A recovery in revenue is observable starting in late 2024, with a peak of 12.2 billion USD recorded in December 2025. Despite this increase in top-line growth, the gross profit margin did not revert to the levels seen in early 2022, remaining at 40.93% during the December 2025 peak.
The results suggest that while revenue growth has resumed in the latter part of the observed timeframe, the cost structure has undergone a fundamental shift. The inability of the gross profit margin to recover to previous highs despite increasing revenues indicates a permanent change in the cost of goods sold or a shift in the product mix toward lower-margin offerings.
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Operating Profit Margin
Thermo Fisher Scientific Inc., operating profit margin calculation (quarterly data)
| Jun 27, 2026 | Mar 28, 2026 | Dec 31, 2025 | Sep 27, 2025 | Jun 28, 2025 | Mar 29, 2025 | Dec 31, 2024 | Sep 28, 2024 | Jun 29, 2024 | Mar 30, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jul 1, 2023 | Apr 1, 2023 | Dec 31, 2022 | Oct 1, 2022 | Jul 2, 2022 | Apr 2, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Operating income | 2,087) | 1,863) | 2,255) | 1,941) | 1,834) | 1,716) | 2,016) | 1,838) | 1,820) | 1,663) | 1,854) | 1,864) | 1,578) | 1,563) | 1,861) | 1,710) | 2,001) | 2,821) | ||||||
| Revenues | 11,994) | 11,005) | 12,215) | 11,122) | 10,855) | 10,364) | 11,395) | 10,598) | 10,541) | 10,345) | 10,886) | 10,574) | 10,687) | 10,710) | 11,450) | 10,677) | 10,970) | 11,818) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| Operating profit margin1 | 17.58% | 17.46% | 17.38% | 17.16% | 17.13% | 17.23% | 17.11% | 16.93% | 17.01% | 16.38% | 16.00% | 15.81% | 15.42% | 16.29% | 18.69% | 20.54% | 22.51% | 23.83% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Operating Profit Margin, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 26.20% | 24.41% | 24.65% | 15.16% | 18.80% | 17.56% | 16.22% | 24.89% | 22.31% | 23.50% | 23.49% | 27.32% | 31.03% | 28.49% | 31.21% | 30.59% | 30.33% | 32.68% | ||||||
| Amgen Inc. | 31.51% | 29.77% | 25.83% | 25.14% | 24.45% | 22.71% | 22.66% | 19.97% | 20.96% | 24.72% | 29.35% | 34.55% | 37.50% | 36.07% | 38.57% | 39.31% | 38.04% | 32.78% | ||||||
| Bristol-Myers Squibb Co. | 23.83% | 20.55% | 20.75% | 18.86% | 16.70% | 15.24% | -15.50% | -14.05% | -14.39% | -14.30% | 16.18% | 16.96% | 17.29% | 18.13% | 17.96% | 19.04% | 18.19% | 16.79% | ||||||
| Danaher Corp. | 20.42% | 19.21% | 19.09% | 19.01% | 18.39% | 20.26% | 20.37% | 20.11% | 21.22% | 21.05% | 21.77% | 23.83% | 25.06% | 27.02% | 27.61% | 27.35% | 25.44% | 25.23% | ||||||
| Eli Lilly & Co. | 42.22% | 43.63% | 40.35% | 38.84% | 32.37% | 28.74% | 28.64% | 24.81% | 23.28% | 20.80% | 18.92% | 18.42% | 24.17% | 22.45% | 24.97% | 24.65% | 25.50% | 25.94% | ||||||
| Gilead Sciences Inc. | -8.37% | 35.46% | 34.66% | 36.75% | 28.03% | 28.77% | 5.81% | 2.92% | 9.26% | 5.79% | 28.24% | 30.37% | 31.18% | 33.03% | 27.17% | 22.39% | 25.78% | 26.56% | ||||||
| Johnson & Johnson | 26.47% | 26.39% | 26.85% | 25.44% | 23.67% | 23.59% | 23.42% | 24.42% | 25.31% | 25.04% | 24.90% | 25.55% | 25.61% | 25.21% | 24.63% | 23.89% | 23.47% | 23.76% | ||||||
| Merck & Co. Inc. | 9.58% | 18.18% | 32.64% | 33.73% | 30.00% | 31.51% | 31.03% | 21.60% | 24.75% | 6.93% | 3.92% | 13.08% | 10.34% | 27.85% | 30.27% | 30.66% | 33.04% | 28.85% | ||||||
| Pfizer Inc. | 21.70% | 22.96% | 22.76% | 21.85% | 23.23% | 19.29% | 19.51% | 9.56% | -4.19% | -2.08% | 2.15% | 14.36% | 28.13% | 34.44% | 34.83% | 33.59% | 30.37% | 26.12% | ||||||
| Regeneron Pharmaceuticals Inc. | 24.74% | 24.32% | 24.95% | 25.89% | 27.02% | 27.20% | 28.10% | 28.69% | 28.95% | 29.40% | 30.85% | 32.23% | 34.20% | 35.79% | 38.93% | 45.45% | 48.19% | 55.08% | ||||||
| Vertex Pharmaceuticals Inc. | 37.95% | 38.31% | 34.77% | 34.06% | 34.36% | -6.69% | -2.11% | -2.54% | -3.37% | 41.16% | 38.83% | 40.16% | 41.72% | 43.93% | 48.23% | 47.72% | 48.85% | 36.93% | ||||||
Based on: 10-Q (reporting date: 2026-06-27), 10-Q (reporting date: 2026-03-28), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).
1 Q2 2026 Calculation
Operating profit margin = 100
× (Operating incomeQ2 2026
+ Operating incomeQ1 2026
+ Operating incomeQ4 2025
+ Operating incomeQ3 2025)
÷ (RevenuesQ2 2026
+ RevenuesQ1 2026
+ RevenuesQ4 2025
+ RevenuesQ3 2025)
= 100 × (2,087 + 1,863 + 2,255 + 1,941)
÷ (11,994 + 11,005 + 12,215 + 11,122)
= 17.58%
2 Click competitor name to see calculations.
The operating profit margin exhibits a distinct U-shaped trajectory over the analyzed period, characterized by a sharp initial contraction followed by a sustained, incremental recovery. The margin peaked at 23.83% in April 2022 before descending to a cyclical low in mid-2023, subsequently stabilizing and trending upward through June 2026.
- Margin Contraction Phase
- A significant downward trend in profitability is observed from April 2, 2022, to July 1, 2023. During this window, the operating profit margin declined from 23.83% to 15.42%. This compression occurred despite revenues remaining relatively robust, suggesting that the decline was driven primarily by increasing operating expenses or a shift in product mix rather than a collapse in top-line sales.
- Stabilization and Recovery Phase
- Following the trough in July 2023, a consistent recovery pattern emerged. From September 30, 2023, through June 27, 2026, the operating profit margin climbed steadily from 15.81% to 17.58%. This gradual improvement indicates a successful effort to optimize cost structures or regain pricing power, as the margin increased even during quarters where revenue remained flat.
- Revenue and Operating Income Correlation
- Operating income reached a period high of 2,821 million US$ in April 2022 and a low of 1,563 million US$ in April 2023. While revenues fluctuated between approximately 10.3 billion and 12.2 billion US$, the operating income did not always move in lockstep with revenue. For instance, the peak revenue of 12,215 million US$ in December 2025 coincided with an operating profit margin of 17.38%, which, while higher than the 2023 lows, remained significantly below the 2022 peak.
Overall, the operational efficiency of the entity has not returned to the levels seen in early 2022, but the trend from 2023 onwards demonstrates a stabilized and improving margin profile, ending the period at 17.58%.
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Net Profit Margin
Thermo Fisher Scientific Inc., net profit margin calculation (quarterly data)
| Jun 27, 2026 | Mar 28, 2026 | Dec 31, 2025 | Sep 27, 2025 | Jun 28, 2025 | Mar 29, 2025 | Dec 31, 2024 | Sep 28, 2024 | Jun 29, 2024 | Mar 30, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jul 1, 2023 | Apr 1, 2023 | Dec 31, 2022 | Oct 1, 2022 | Jul 2, 2022 | Apr 2, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Net income attributable to Thermo Fisher Scientific Inc. | 1,736) | 1,651) | 1,964) | 1,616) | 1,617) | 1,507) | 1,829) | 1,630) | 1,548) | 1,328) | 1,630) | 1,715) | 1,361) | 1,289) | 1,576) | 1,495) | 1,664) | 2,215) | ||||||
| Revenues | 11,994) | 11,005) | 12,215) | 11,122) | 10,855) | 10,364) | 11,395) | 10,598) | 10,541) | 10,345) | 10,886) | 10,574) | 10,687) | 10,710) | 11,450) | 10,677) | 10,970) | 11,818) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| Net profit margin1 | 15.04% | 15.15% | 15.05% | 15.02% | 15.23% | 15.18% | 14.77% | 14.48% | 14.69% | 14.20% | 13.99% | 13.68% | 13.14% | 13.75% | 15.47% | 15.92% | 17.37% | 18.49% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Net Profit Margin, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 9.80% | 5.79% | 6.91% | 4.00% | 6.45% | 7.31% | 7.59% | 9.22% | 9.71% | 11.02% | 8.95% | 11.81% | 15.50% | 13.37% | 20.39% | 23.19% | 22.04% | 22.00% | ||||||
| Amgen Inc. | 24.11% | 21.98% | 21.94% | 20.31% | 19.75% | 18.10% | 12.77% | 13.58% | 10.60% | 13.35% | 24.96% | 29.52% | 31.52% | 31.77% | 26.42% | 27.88% | 26.73% | 23.42% | ||||||
| Bristol-Myers Squibb Co. | 18.87% | 15.01% | 14.64% | 12.57% | 10.58% | 11.38% | -18.53% | -15.30% | -14.06% | -13.50% | 17.83% | 18.44% | 17.62% | 15.95% | 13.71% | 14.29% | 14.04% | 13.31% | ||||||
| Danaher Corp. | 15.95% | 14.89% | 14.71% | 14.43% | 14.21% | 15.81% | 16.33% | 16.39% | 17.83% | 18.54% | 19.94% | 22.89% | 22.80% | 23.32% | 22.91% | 21.65% | 20.61% | 21.32% | ||||||
| Eli Lilly & Co. | 33.53% | 34.99% | 31.67% | 30.99% | 25.91% | 22.66% | 23.51% | 20.48% | 18.86% | 17.08% | 15.36% | 15.55% | 22.01% | 20.54% | 21.88% | 20.63% | 19.58% | 20.90% | ||||||
| Gilead Sciences Inc. | -10.86% | 31.51% | 29.43% | 28.41% | 21.98% | 20.87% | 1.68% | 0.45% | 3.82% | 1.78% | 21.03% | 21.60% | 20.18% | 20.87% | 17.02% | 12.44% | 15.22% | 16.60% | ||||||
| Johnson & Johnson | 21.48% | 21.83% | 28.46% | 27.26% | 25.00% | 24.41% | 15.84% | 16.74% | 43.91% | 44.92% | 41.28% | 39.58% | 14.52% | 13.77% | 18.90% | 19.95% | 19.21% | 20.90% | ||||||
| Merck & Co. Inc. | 4.77% | 13.59% | 28.08% | 29.63% | 25.79% | 27.27% | 26.68% | 19.23% | 21.98% | 3.76% | 0.61% | 7.77% | 5.34% | 22.52% | 24.49% | 25.88% | 29.00% | 26.27% | ||||||
| Pfizer Inc. | 6.80% | 11.83% | 12.42% | 15.65% | 16.84% | 12.62% | 12.62% | 7.04% | -4.62% | -0.55% | 3.56% | 15.13% | 27.38% | 31.19% | 31.27% | 29.81% | 28.94% | 27.01% | ||||||
| Regeneron Pharmaceuticals Inc. | 27.86% | 29.65% | 31.41% | 32.13% | 31.37% | 31.94% | 31.07% | 33.61% | 32.04% | 29.45% | 30.14% | 30.47% | 33.93% | 33.81% | 35.64% | 39.17% | 39.97% | 48.06% | ||||||
| Vertex Pharmaceuticals Inc. | 35.00% | 35.51% | 32.94% | 31.35% | 31.86% | -8.91% | -4.86% | -4.52% | -4.74% | 39.46% | 36.68% | 35.94% | 35.40% | 35.40% | 37.20% | 37.62% | 38.26% | 30.84% | ||||||
Based on: 10-Q (reporting date: 2026-06-27), 10-Q (reporting date: 2026-03-28), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).
1 Q2 2026 Calculation
Net profit margin = 100
× (Net income attributable to Thermo Fisher Scientific Inc.Q2 2026
+ Net income attributable to Thermo Fisher Scientific Inc.Q1 2026
+ Net income attributable to Thermo Fisher Scientific Inc.Q4 2025
+ Net income attributable to Thermo Fisher Scientific Inc.Q3 2025)
÷ (RevenuesQ2 2026
+ RevenuesQ1 2026
+ RevenuesQ4 2025
+ RevenuesQ3 2025)
= 100 × (1,736 + 1,651 + 1,964 + 1,616)
÷ (11,994 + 11,005 + 12,215 + 11,122)
= 15.04%
2 Click competitor name to see calculations.
The financial performance of Thermo Fisher Scientific Inc. between April 2022 and June 2026 is characterized by an initial period of margin contraction followed by a recovery phase and subsequent stabilization. The net profit margin experienced a significant decline in the first half of the analyzed period before establishing a consistent baseline of approximately 15%.
- Net Profit Margin Trajectory
- A pronounced downward trend is observed from April 2022 to July 2023, where the net profit margin fell from a peak of 18.49% to a trough of 13.14%. Following this low point, a gradual recovery occurred, with margins climbing back to 14.77% by December 2023 and continuing a slow ascent through mid-2025.
- Revenue and Net Income Correlation
- The contraction in profitability mirrored a period of declining revenues, which dropped from 11.8 billion US$ in early 2022 to a low of 10.3 billion US$ by March 2024. The subsequent recovery in the net profit margin was supported by a stabilization in revenue and a general increase in net income, which reached a peak of 1.96 billion US$ in December 2025.
- Profitability Equilibrium
- Beginning in late 2024, the net profit margin entered a phase of high stability. From December 2024 through June 2026, the margin remained tightly range-bound between 15.02% and 15.23%. This indicates a consistent ability to maintain profitability levels regardless of quarterly fluctuations in total revenue, such as the peak observed in December 2025.
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Return on Equity (ROE)
Thermo Fisher Scientific Inc., ROE calculation (quarterly data)
| Jun 27, 2026 | Mar 28, 2026 | Dec 31, 2025 | Sep 27, 2025 | Jun 28, 2025 | Mar 29, 2025 | Dec 31, 2024 | Sep 28, 2024 | Jun 29, 2024 | Mar 30, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jul 1, 2023 | Apr 1, 2023 | Dec 31, 2022 | Oct 1, 2022 | Jul 2, 2022 | Apr 2, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Net income attributable to Thermo Fisher Scientific Inc. | 1,736) | 1,651) | 1,964) | 1,616) | 1,617) | 1,507) | 1,829) | 1,630) | 1,548) | 1,328) | 1,630) | 1,715) | 1,361) | 1,289) | 1,576) | 1,495) | 1,664) | 2,215) | ||||||
| Total Thermo Fisher Scientific Inc. shareholders’ equity | 52,679) | 51,934) | 53,407) | 51,018) | 50,512) | 49,390) | 49,584) | 48,992) | 47,432) | 45,516) | 46,735) | 45,328) | 43,752) | 42,257) | 43,978) | 43,549) | 42,293) | 40,956) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| ROE1 | 13.23% | 13.19% | 12.55% | 12.88% | 13.03% | 13.19% | 12.78% | 12.52% | 13.12% | 13.26% | 12.83% | 13.11% | 13.08% | 14.26% | 15.80% | 16.15% | 17.59% | 18.56% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| ROE, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | — | — | — | — | — | 295.42% | 128.66% | 84.91% | 78.77% | 74.85% | 46.94% | 53.86% | 67.50% | 57.14% | 68.60% | 83.83% | 86.24% | 76.64% | ||||||
| Amgen Inc. | 74.80% | 84.87% | 89.06% | 72.82% | 89.11% | 95.59% | 69.59% | 56.20% | 52.83% | 74.93% | 107.78% | 98.82% | 117.67% | 148.04% | 178.97% | 187.11% | 271.85% | 624.78% | ||||||
| Bristol-Myers Squibb Co. | 41.59% | 36.25% | 38.19% | 32.55% | 28.96% | 31.16% | -54.78% | -42.34% | -38.44% | -37.28% | 27.27% | 28.57% | 24.91% | 22.97% | 20.37% | 20.44% | 20.30% | 19.79% | ||||||
| Danaher Corp. | 7.61% | 6.97% | 6.88% | 6.86% | 6.52% | 7.40% | 7.87% | 7.59% | 8.42% | 8.24% | 8.91% | 11.29% | 12.30% | 13.47% | 14.39% | 14.40% | 13.63% | 13.93% | ||||||
| Eli Lilly & Co. | 78.84% | 81.02% | 77.78% | 77.38% | 75.52% | 70.45% | 74.62% | 58.78% | 54.14% | 47.91% | 48.65% | 44.46% | 58.73% | 50.82% | 58.64% | 59.91% | 66.61% | 65.69% | ||||||
| Gilead Sciences Inc. | -27.39% | 39.19% | 37.48% | 37.65% | 32.08% | 31.13% | 2.48% | 0.69% | 5.77% | 2.77% | 24.81% | 26.33% | 25.92% | 26.59% | 21.62% | 15.82% | 20.44% | 22.66% | ||||||
| Johnson & Johnson | 24.76% | 25.92% | 32.87% | 31.69% | 28.88% | 27.92% | 19.68% | 20.93% | 53.14% | 54.95% | 51.11% | 48.61% | 17.37% | 17.95% | 23.36% | 25.68% | 24.05% | 26.54% | ||||||
| Merck & Co. Inc. | 7.57% | 19.48% | 34.70% | 36.71% | 33.49% | 36.07% | 36.96% | 27.30% | 31.52% | 5.71% | 0.97% | 11.17% | 8.04% | 27.82% | 31.57% | 34.32% | 38.34% | 34.68% | ||||||
| Pfizer Inc. | 5.09% | 8.31% | 8.99% | 10.59% | 12.12% | 8.73% | 9.11% | 4.61% | -2.96% | -0.33% | 2.38% | 10.81% | 21.68% | 28.77% | 32.79% | 32.14% | 33.61% | 30.29% | ||||||
| Regeneron Pharmaceuticals Inc. | 13.65% | 14.08% | 14.41% | 14.79% | 14.89% | 15.31% | 15.03% | 15.87% | 15.32% | 14.29% | 15.22% | 16.03% | 17.90% | 17.80% | 19.14% | 25.05% | 27.49% | 39.84% | ||||||
| Vertex Pharmaceuticals Inc. | 21.76% | 22.41% | 21.18% | 21.22% | 21.18% | -5.99% | -3.26% | -3.07% | -3.32% | 21.67% | 20.59% | 21.01% | 21.75% | 22.59% | 23.88% | 25.12% | 26.77% | 22.47% | ||||||
Based on: 10-Q (reporting date: 2026-06-27), 10-Q (reporting date: 2026-03-28), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).
1 Q2 2026 Calculation
ROE = 100
× (Net income attributable to Thermo Fisher Scientific Inc.Q2 2026
+ Net income attributable to Thermo Fisher Scientific Inc.Q1 2026
+ Net income attributable to Thermo Fisher Scientific Inc.Q4 2025
+ Net income attributable to Thermo Fisher Scientific Inc.Q3 2025)
÷ Total Thermo Fisher Scientific Inc. shareholders’ equity
= 100 × (1,736 + 1,651 + 1,964 + 1,616)
÷ 52,679 = 13.23%
2 Click competitor name to see calculations.
The Return on Equity (ROE) exhibits a two-phase trajectory characterized by an initial contraction followed by a sustained period of stabilization. From April 2022 to December 2023, the ROE declined from a peak of 18.56% to 12.83%. In the subsequent period, spanning January 2024 through June 2026, the ratio reached a plateau, fluctuating within a narrow range between 12.52% and 13.26%.
- Net Income Trends
- Net income attributable to shareholders experienced significant volatility, starting at a high of $2,215 million in April 2022 and reaching a trough of $1,289 million by April 2023. Although earnings recovered and stabilized between $1,500 million and $1,900 million in the following years, they remained below the 2022 peak, which contributed to the overall reduction in the ROE percentage.
- Equity Base Expansion
- A consistent upward trend is observed in total shareholders' equity, which grew from $40,956 million in April 2022 to $52,679 million by June 2026. This expansion of the capital base acted as a downward pressure on the ROE, as the increase in the denominator outpaced the growth in net income during the analyzed period.
- Profitability Equilibrium
- The data indicates the establishment of a new profitability equilibrium starting in mid-2023. Despite ongoing quarterly fluctuations in net income, the ROE remained remarkably steady around the 13% mark for over two years. This suggests that the company's earnings generation has aligned with its expanded equity structure, resulting in a stabilized return profile after the volatility of 2022.
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Return on Assets (ROA)
Thermo Fisher Scientific Inc., ROA calculation (quarterly data)
| Jun 27, 2026 | Mar 28, 2026 | Dec 31, 2025 | Sep 27, 2025 | Jun 28, 2025 | Mar 29, 2025 | Dec 31, 2024 | Sep 28, 2024 | Jun 29, 2024 | Mar 30, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jul 1, 2023 | Apr 1, 2023 | Dec 31, 2022 | Oct 1, 2022 | Jul 2, 2022 | Apr 2, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Net income attributable to Thermo Fisher Scientific Inc. | 1,736) | 1,651) | 1,964) | 1,616) | 1,617) | 1,507) | 1,829) | 1,630) | 1,548) | 1,328) | 1,630) | 1,715) | 1,361) | 1,289) | 1,576) | 1,495) | 1,664) | 2,215) | ||||||
| Total assets | 113,174) | 113,281) | 110,343) | 103,020) | 101,230) | 99,041) | 97,321) | 100,364) | 98,496) | 97,095) | 98,726) | 97,057) | 94,105) | 94,658) | 97,154) | 90,536) | 90,579) | 92,747) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| ROA1 | 6.16% | 6.05% | 6.08% | 6.38% | 6.50% | 6.58% | 6.51% | 6.11% | 6.32% | 6.21% | 6.07% | 6.12% | 6.08% | 6.36% | 7.15% | 7.77% | 8.21% | 8.20% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| ROA, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 4.67% | 2.66% | 3.15% | 1.78% | 2.74% | 3.08% | 3.17% | 3.57% | 3.76% | 4.03% | 3.61% | 4.78% | 6.42% | 5.64% | 8.53% | 9.49% | 8.83% | 8.71% | ||||||
| Amgen Inc. | 9.14% | 8.43% | 8.51% | 7.77% | 7.53% | 6.64% | 4.45% | 4.65% | 3.44% | 4.05% | 6.91% | 8.36% | 8.84% | 8.92% | 10.06% | 10.73% | 11.09% | 9.67% | ||||||
| Bristol-Myers Squibb Co. | 10.59% | 8.41% | 7.83% | 6.23% | 5.33% | 5.86% | -9.66% | -7.75% | -6.91% | -6.21% | 8.43% | 9.08% | 8.52% | 7.75% | 6.53% | 6.80% | 6.59% | 6.07% | ||||||
| Danaher Corp. | 4.33% | 4.42% | 4.33% | 4.38% | 4.18% | 4.76% | 5.03% | 4.83% | 5.35% | 5.28% | 5.64% | 6.74% | 7.49% | 8.15% | 8.55% | 8.35% | 7.76% | 7.74% | ||||||
| Eli Lilly & Co. | 18.77% | 21.68% | 18.35% | 16.02% | 13.67% | 12.42% | 13.45% | 11.07% | 10.22% | 9.60% | 8.19% | 8.61% | 11.85% | 10.70% | 12.62% | 12.71% | 12.09% | 13.06% | ||||||
| Gilead Sciences Inc. | -6.56% | 16.38% | 14.42% | 13.86% | 11.33% | 10.57% | 0.81% | 0.23% | 1.97% | 0.86% | 9.12% | 9.42% | 8.80% | 9.02% | 7.27% | 5.33% | 6.58% | 7.16% | ||||||
| Johnson & Johnson | 10.46% | 10.47% | 13.46% | 13.03% | 11.72% | 11.26% | 7.81% | 8.24% | 20.99% | 22.37% | 20.98% | 20.85% | 6.81% | 6.49% | 9.57% | 10.94% | 10.33% | 11.12% | ||||||
| Merck & Co. Inc. | 2.44% | 6.94% | 13.34% | 14.69% | 13.96% | 15.14% | 14.62% | 10.34% | 12.20% | 2.18% | 0.34% | 4.32% | 2.98% | 12.09% | 13.30% | 14.25% | 15.48% | 13.29% | ||||||
| Pfizer Inc. | 2.15% | 3.61% | 3.73% | 4.71% | 5.22% | 3.79% | 3.76% | 1.94% | -1.20% | -0.14% | 0.94% | 4.87% | 9.75% | 14.85% | 15.91% | 15.32% | 15.01% | 13.58% | ||||||
| Regeneron Pharmaceuticals Inc. | 10.37% | 10.82% | 11.11% | 11.40% | 11.67% | 11.98% | 11.69% | 12.43% | 11.98% | 11.22% | 11.95% | 12.41% | 14.02% | 13.91% | 14.85% | 19.40% | 20.90% | 30.11% | ||||||
| Vertex Pharmaceuticals Inc. | 16.06% | 16.38% | 15.42% | 14.78% | 15.13% | -4.32% | -2.38% | -2.16% | -2.43% | 16.81% | 15.92% | 15.97% | 16.54% | 17.18% | 18.30% | 19.59% | 20.50% | 17.19% | ||||||
Based on: 10-Q (reporting date: 2026-06-27), 10-Q (reporting date: 2026-03-28), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-27), 10-Q (reporting date: 2025-06-28), 10-Q (reporting date: 2025-03-29), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-28), 10-Q (reporting date: 2024-06-29), 10-Q (reporting date: 2024-03-30), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-07-01), 10-Q (reporting date: 2023-04-01), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-01), 10-Q (reporting date: 2022-07-02), 10-Q (reporting date: 2022-04-02).
1 Q2 2026 Calculation
ROA = 100
× (Net income attributable to Thermo Fisher Scientific Inc.Q2 2026
+ Net income attributable to Thermo Fisher Scientific Inc.Q1 2026
+ Net income attributable to Thermo Fisher Scientific Inc.Q4 2025
+ Net income attributable to Thermo Fisher Scientific Inc.Q3 2025)
÷ Total assets
= 100 × (1,736 + 1,651 + 1,964 + 1,616)
÷ 113,174 = 6.16%
2 Click competitor name to see calculations.
An analysis of the profitability metrics reveals a period of contraction in asset efficiency followed by a phase of relative stability. The Return on Assets (ROA) experienced a notable decline from its peak in early 2022, subsequently establishing a new baseline throughout 2023, 2024, and into 2026.
- Return on Assets (ROA) Trend
- A downward trajectory is observed in the first half of the analyzed period, with ROA falling from 8.21% in July 2022 to a low of 6.07% by December 2023. Following this decline, the ratio entered a period of stabilization, fluctuating within a narrow band between 6.05% and 6.58%. The most recent data indicates a consistent performance level hovering around 6.16%.
- Net Income Fluctuations
- Net income exhibited significant volatility, starting at 2,215 million US$ in April 2022 and reaching a trough of 1,289 million US$ in April 2023. A gradual recovery period followed, with income peaking again at 1,964 million US$ in December 2025 before settling in the 1,650 to 1,736 million US$ range by mid-2026.
- Asset Base Expansion
- Total assets demonstrated a consistent long-term upward trend, growing from 92,747 million US$ in April 2022 to 113,174 million US$ by June 2026. This expansion represents a steady increase in the company's resource base, though the growth in assets outpaced the growth in net income during several intervals.
- Efficiency Correlation
- The contraction in ROA during 2022 and 2023 is attributable to the simultaneous decrease in net income and a generally expanding asset base. While net income began to recover in 2024 and 2025, the continued growth of total assets to over 113 billion US$ served as a drag on the ROA percentage, preventing a return to the 8% levels observed in early 2022.
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