Analysis of Profitability Ratios
Quarterly Data
Profitability ratios measure the company ability to generate profitable sales from its resources (assets).
Profitability Ratios (Summary)
Return on Sales
Return on Investment
Danaher Corp., profitability ratios (quarterly data)
Based on: 10-Q (reporting date: 2026-09-25), 10-Q (reporting date: 2026-06-26), 10-Q (reporting date: 2026-03-27), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-26), 10-Q (reporting date: 2025-06-27), 10-Q (reporting date: 2025-03-28), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-27), 10-Q (reporting date: 2024-06-28), 10-Q (reporting date: 2024-03-29), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-29), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-07-01), 10-Q (reporting date: 2022-04-01).
Profitability and efficiency metrics exhibit a period of contraction starting in early 2023, reaching a trough in mid-2025, followed by a moderate recovery phase through September 2026. While the gross margin remained relatively resilient, there was a significant decline in operating and net profit margins, alongside a substantial reduction in the returns on equity and assets.
- Gross Profit Margin
- The gross profit margin demonstrated the highest level of stability among the analyzed ratios. It began at 60.77% in April 2022 and maintained levels above 60% through early 2023. A gradual decline occurred, reaching a low of 58.39% in March 2024. Despite a slight recovery to 59.50% by December 2024, the margin trended downward again toward the end of the period, closing at 58.59% in September 2026.
- Operating and Net Profit Margins
- Both operating and net margins followed a similar trajectory of expansion followed by sharp contraction. Operating profit margin peaked at 27.61% in December 2022 before entering a sustained decline to a minimum of 18.39% in June 2025. Similarly, the net profit margin peaked at 23.32% in March 2023 and declined to a low of 14.21% in June 2025. By September 2026, these figures showed partial recovery, with the operating margin reaching 20.38% and the net margin rising to 16.91%.
- Return on Equity (ROE)
- Return on equity experienced a marked deterioration over the analyzed period. After remaining stable between 13% and 14% through early 2023, ROE declined precipitously, reaching 8.91% by December 2023 and hitting a floor of 6.52% in June 2025. A gradual upward trend is observed in the final quarters, with ROE improving to 8.08% by September 2026, though it remained significantly below 2022 levels.
- Return on Assets (ROA)
- Return on assets mirrored the trend seen in ROE, indicating a decrease in overall asset utilization efficiency. ROA peaked at 8.55% in December 2022 before trending downward to 4.18% in June 2025. The period concluded with a slight recovery to 4.64% by September 2026.
The divergence between the relatively stable gross profit margin and the sharper declines in operating and net margins suggests that the reduction in profitability was driven primarily by increased operating expenses or non-operating costs rather than a fundamental collapse in pricing power or cost of goods sold. The synchronized decline in ROE and ROA further indicates a period of diminished financial efficiency that only began to stabilize in late 2025.
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Gross Profit Margin
Danaher Corp., gross profit margin calculation (quarterly data)
| Sep 25, 2026 | Jun 26, 2026 | Mar 27, 2026 | Dec 31, 2025 | Sep 26, 2025 | Jun 27, 2025 | Mar 28, 2025 | Dec 31, 2024 | Sep 27, 2024 | Jun 28, 2024 | Mar 29, 2024 | Dec 31, 2023 | Sep 29, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jul 1, 2022 | Apr 1, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Gross profit | 3,837) | 3,611) | 3,591) | 3,966) | 3,523) | 3,523) | 3,511) | 3,890) | 3,401) | 3,428) | 3,487) | 3,779) | 3,275) | 3,318) | 3,662) | 4,939) | 4,584) | 4,721) | 4,705) | ||||||
| Sales | 6,554) | 6,265) | 5,951) | 6,838) | 6,053) | 5,936) | 5,741) | 6,538) | 5,798) | 5,743) | 5,796) | 6,405) | 5,624) | 5,912) | 5,949) | 8,369) | 7,663) | 7,751) | 7,688) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| Gross profit margin1 | 58.59% | 58.51% | 58.94% | 59.11% | 59.53% | 59.66% | 59.74% | 59.50% | 59.37% | 59.27% | 58.39% | 58.74% | 58.77% | 59.17% | 60.22% | 60.21% | 60.65% | 60.77% | 60.77% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| Gross Profit Margin, Competitors2 | |||||||||||||||||||||||||
| AbbVie Inc. | 73.72% | 71.48% | 70.68% | 70.24% | 69.74% | 70.93% | 70.69% | 69.99% | 67.21% | 62.75% | 62.28% | 62.42% | 65.76% | 68.91% | 69.43% | 70.00% | 69.62% | 70.48% | 69.53% | ||||||
| Amgen Inc. | 69.41% | 67.97% | 66.72% | 65.75% | 64.71% | 62.99% | 61.48% | 59.85% | 58.71% | 61.56% | 64.76% | 68.60% | 72.35% | 72.87% | 73.65% | 74.17% | 73.99% | 74.00% | 73.30% | ||||||
| Bristol-Myers Squibb Co. | 69.24% | 70.16% | 70.46% | 71.08% | 69.50% | 70.29% | 70.47% | 71.08% | 74.91% | 75.38% | 75.71% | 76.24% | 76.54% | 77.01% | 77.68% | 78.04% | 78.82% | 79.13% | 79.62% | ||||||
| Eli Lilly & Co. | 83.63% | 83.40% | 82.83% | 83.04% | 83.03% | 82.64% | 81.70% | 81.31% | 80.91% | 80.75% | 80.16% | 79.25% | 78.67% | 77.77% | 77.67% | 76.77% | 75.61% | 75.98% | 74.40% | ||||||
| Gilead Sciences Inc. | 79.79% | 79.15% | 79.01% | 78.44% | 78.31% | 78.42% | 78.17% | 78.15% | 75.98% | 75.56% | 75.62% | 75.87% | 78.66% | 79.27% | 78.94% | 79.03% | 74.31% | 75.30% | 75.50% | ||||||
| Johnson & Johnson | 67.56% | 67.91% | 67.82% | 67.88% | 68.08% | 67.92% | 68.30% | 69.07% | 69.05% | 69.06% | 69.20% | 68.82% | 68.54% | 68.06% | 67.34% | 67.26% | 67.43% | 67.86% | 67.97% | ||||||
| Merck & Co. Inc. | 71.75% | 72.97% | 73.91% | 74.80% | 77.18% | 76.60% | 76.42% | 76.32% | 75.82% | 75.25% | 74.37% | 73.17% | 72.86% | 72.96% | 72.43% | 70.63% | 70.49% | 70.41% | 70.72% | ||||||
| Pfizer Inc. | 73.38% | 73.18% | 73.51% | 74.33% | 73.39% | 72.12% | 72.28% | 71.94% | 67.73% | 58.18% | 58.09% | 58.10% | 60.97% | 69.61% | 68.61% | 65.77% | 65.53% | 62.18% | 60.35% | ||||||
| Regeneron Pharmaceuticals Inc. | 85.77% | 84.86% | 84.55% | 85.35% | 85.39% | 85.57% | 85.79% | 86.13% | 86.12% | 86.16% | 86.32% | 86.16% | 85.96% | 86.42% | 86.96% | 87.18% | 85.39% | 84.97% | 84.65% | ||||||
| Thermo Fisher Scientific Inc. | 41.08% | 40.80% | 40.78% | 40.93% | 41.27% | 41.18% | 41.34% | 41.28% | 40.77% | 40.76% | 40.40% | 39.90% | 39.87% | 39.75% | 40.28% | 42.24% | 44.42% | 46.63% | 48.37% | ||||||
| Vertex Pharmaceuticals Inc. | 85.53% | 86.00% | 86.24% | 86.24% | 86.28% | 86.11% | 86.03% | 86.11% | 86.12% | 86.45% | 86.86% | 87.21% | 87.80% | 87.92% | 88.04% | 87.90% | 88.00% | 88.13% | 87.95% | ||||||
Based on: 10-Q (reporting date: 2026-09-25), 10-Q (reporting date: 2026-06-26), 10-Q (reporting date: 2026-03-27), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-26), 10-Q (reporting date: 2025-06-27), 10-Q (reporting date: 2025-03-28), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-27), 10-Q (reporting date: 2024-06-28), 10-Q (reporting date: 2024-03-29), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-29), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-07-01), 10-Q (reporting date: 2022-04-01).
1 Q3 2026 Calculation
Gross profit margin = 100
× (Gross profitQ3 2026
+ Gross profitQ2 2026
+ Gross profitQ1 2026
+ Gross profitQ4 2025)
÷ (SalesQ3 2026
+ SalesQ2 2026
+ SalesQ1 2026
+ SalesQ4 2025)
= 100 × (3,837 + 3,611 + 3,591 + 3,966)
÷ (6,554 + 6,265 + 5,951 + 6,838)
= 58.59%
2 Click competitor name to see calculations.
The gross profit margin exhibits a general downward trajectory over the analyzed period, declining from a peak of 60.77% in early 2022 to 58.59% by September 2026. This overall compression suggests a gradual increase in the cost of goods sold relative to revenue or a shift in product mix affecting overall profitability.
- Initial Contraction Phase (2022-2023)
- A period of relative stability was observed throughout 2022, with margins remaining above 60%. However, a significant contraction occurred in the first half of 2023, where the gross profit margin dropped from 60.22% in March 2023 to 58.77% by September 2023. This decline coincided with a substantial reduction in quarterly sales, which fell from peak levels of approximately 8.37 billion USD in late 2022 to between 5.6 billion and 5.9 billion USD in 2023.
- Recovery and Stabilization Phase (2024-Early 2025)
- A gradual recovery in profitability is evident starting in mid-2024. The gross profit margin climbed steadily from 58.39% in March 2024 to a local peak of 59.74% in March 2025. This period indicates improved cost management or pricing adjustments, as margins improved even while sales fluctuated between 5.7 billion and 6.8 billion USD.
- Secondary Decline and Current Status (2025-2026)
- Following the March 2025 peak, a secondary downward trend is observed. The margin declined steadily through the remainder of 2025 and into 2026, reaching a low of 58.51% in June 2026 before a slight uptick to 58.59% in September 2026. This indicates a persistent challenge in maintaining the margin recovery achieved in the previous year.
- Revenue and Profit Correlation
- Gross profit figures closely track the movement of total sales, but the shrinking margin indicates that gross profit is not growing proportionally with revenue. For instance, while sales in December 2024 (6.54 billion USD) were higher than in December 2022 (8.37 billion USD), the corresponding gross profit in 2024 (3.89 billion USD) was significantly lower than in 2022 (4.94 billion USD), reflecting the eroded margin percentage over the four-year span.
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Operating Profit Margin
Danaher Corp., operating profit margin calculation (quarterly data)
| Sep 25, 2026 | Jun 26, 2026 | Mar 27, 2026 | Dec 31, 2025 | Sep 26, 2025 | Jun 27, 2025 | Mar 28, 2025 | Dec 31, 2024 | Sep 27, 2024 | Jun 28, 2024 | Mar 29, 2024 | Dec 31, 2023 | Sep 29, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jul 1, 2022 | Apr 1, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Operating profit | 1,245) | 1,127) | 1,344) | 1,502) | 1,154) | 760) | 1,274) | 1,425) | 958) | 1,168) | 1,312) | 1,337) | 1,185) | 1,163) | 1,517) | 2,296) | 2,015) | 2,205) | 2,172) | ||||||
| Sales | 6,554) | 6,265) | 5,951) | 6,838) | 6,053) | 5,936) | 5,741) | 6,538) | 5,798) | 5,743) | 5,796) | 6,405) | 5,624) | 5,912) | 5,949) | 8,369) | 7,663) | 7,751) | 7,688) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| Operating profit margin1 | 20.38% | 20.42% | 19.21% | 19.09% | 19.01% | 18.39% | 20.26% | 20.37% | 20.11% | 21.22% | 21.05% | 21.77% | 23.83% | 25.06% | 27.02% | 27.61% | 27.35% | 25.44% | 25.23% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| Operating Profit Margin, Competitors2 | |||||||||||||||||||||||||
| AbbVie Inc. | 32.16% | 26.20% | 24.41% | 24.65% | 15.16% | 18.80% | 17.56% | 16.22% | 24.89% | 22.31% | 23.50% | 23.49% | 27.32% | 31.03% | 28.49% | 31.21% | 30.59% | 30.33% | 32.68% | ||||||
| Amgen Inc. | 34.08% | 31.51% | 29.77% | 25.83% | 25.14% | 24.45% | 22.71% | 22.66% | 19.97% | 20.96% | 24.72% | 29.35% | 34.55% | 37.50% | 36.07% | 38.57% | 39.31% | 38.04% | 32.78% | ||||||
| Bristol-Myers Squibb Co. | 23.10% | 23.83% | 20.55% | 20.75% | 18.86% | 16.70% | 15.24% | -15.50% | -14.05% | -14.39% | -14.30% | 16.18% | 16.96% | 17.29% | 18.13% | 17.96% | 19.04% | 18.19% | 16.79% | ||||||
| Eli Lilly & Co. | 40.34% | 42.22% | 43.63% | 40.35% | 38.84% | 32.37% | 28.74% | 28.64% | 24.81% | 23.28% | 20.80% | 18.92% | 18.42% | 24.17% | 22.45% | 24.97% | 24.65% | 25.50% | 25.94% | ||||||
| Gilead Sciences Inc. | -7.68% | -8.37% | 35.46% | 34.66% | 36.75% | 28.03% | 28.77% | 5.81% | 2.92% | 9.26% | 5.79% | 28.24% | 30.37% | 31.18% | 33.03% | 27.17% | 22.39% | 25.78% | 26.56% | ||||||
| Johnson & Johnson | 24.90% | 26.47% | 26.39% | 26.85% | 25.44% | 23.67% | 23.59% | 23.42% | 24.42% | 25.31% | 25.04% | 24.90% | 25.55% | 25.61% | 25.21% | 24.63% | 23.89% | 23.47% | 23.76% | ||||||
| Merck & Co. Inc. | 8.10% | 9.58% | 18.18% | 32.64% | 33.73% | 30.00% | 31.51% | 31.03% | 21.60% | 24.75% | 6.93% | 3.92% | 13.08% | 10.34% | 27.85% | 30.27% | 30.66% | 33.04% | 28.85% | ||||||
| Pfizer Inc. | 21.44% | 21.70% | 22.96% | 22.76% | 21.85% | 23.23% | 19.29% | 19.51% | 9.56% | -4.19% | -2.08% | 2.15% | 14.36% | 28.13% | 34.44% | 34.83% | 33.59% | 30.37% | 26.12% | ||||||
| Regeneron Pharmaceuticals Inc. | 28.79% | 24.74% | 24.32% | 24.95% | 25.89% | 27.02% | 27.20% | 28.10% | 28.69% | 28.95% | 29.40% | 30.85% | 32.23% | 34.20% | 35.79% | 38.93% | 45.45% | 48.19% | 55.08% | ||||||
| Thermo Fisher Scientific Inc. | 17.88% | 17.58% | 17.46% | 17.38% | 17.16% | 17.13% | 17.23% | 17.11% | 16.93% | 17.01% | 16.38% | 16.00% | 15.81% | 15.42% | 16.29% | 18.69% | 20.54% | 22.51% | 23.83% | ||||||
| Vertex Pharmaceuticals Inc. | 33.23% | 37.95% | 38.31% | 34.77% | 34.06% | 34.36% | -6.69% | -2.11% | -2.54% | -3.37% | 41.16% | 38.83% | 40.16% | 41.72% | 43.93% | 48.23% | 47.72% | 48.85% | 36.93% | ||||||
Based on: 10-Q (reporting date: 2026-09-25), 10-Q (reporting date: 2026-06-26), 10-Q (reporting date: 2026-03-27), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-26), 10-Q (reporting date: 2025-06-27), 10-Q (reporting date: 2025-03-28), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-27), 10-Q (reporting date: 2024-06-28), 10-Q (reporting date: 2024-03-29), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-29), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-07-01), 10-Q (reporting date: 2022-04-01).
1 Q3 2026 Calculation
Operating profit margin = 100
× (Operating profitQ3 2026
+ Operating profitQ2 2026
+ Operating profitQ1 2026
+ Operating profitQ4 2025)
÷ (SalesQ3 2026
+ SalesQ2 2026
+ SalesQ1 2026
+ SalesQ4 2025)
= 100 × (1,245 + 1,127 + 1,344 + 1,502)
÷ (6,554 + 6,265 + 5,951 + 6,838)
= 20.38%
2 Click competitor name to see calculations.
The operating profit margin exhibits a general downward trajectory over the analyzed period, transitioning from a peak in late 2022 to a lower, stabilized baseline by late 2026. The overall trend is characterized by an initial period of expansion, followed by a sustained contraction and a subsequent phase of marginal recovery.
- Peak Profitability Phase
- During the first three quarters of 2022, the operating profit margin demonstrated strength and growth, rising from 25.23% in April 2022 to a period high of 27.61% by December 2022. This peak coincided with the highest levels of sales and operating profit recorded throughout the entire timeframe.
- Operational Contraction and Margin Erosion
- A significant decline in profitability is observed starting in early 2023. The operating profit margin fell from 27.02% in March 2023 to 20.11% by September 2024. This compression was accompanied by a sharp reduction in sales, which shifted from the 7-8 billion US dollar range seen in 2022 to a lower range between 5.6 and 6.5 billion US dollars throughout 2023 and 2024.
- Trough and Stabilization Period
- The operating profit margin reached its lowest point of 18.39% in June 2025. Following this trough, a gradual recovery is evident, with the margin incrementally climbing back to 20.38% by September 2026. While this recovery indicates a return to stability, the margin remains significantly lower than the levels maintained during the 2022 peak.
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Net Profit Margin
Danaher Corp., net profit margin calculation (quarterly data)
| Sep 25, 2026 | Jun 26, 2026 | Mar 27, 2026 | Dec 31, 2025 | Sep 26, 2025 | Jun 27, 2025 | Mar 28, 2025 | Dec 31, 2024 | Sep 27, 2024 | Jun 28, 2024 | Mar 29, 2024 | Dec 31, 2023 | Sep 29, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jul 1, 2022 | Apr 1, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Net earnings | 1,235) | 870) | 1,029) | 1,197) | 908) | 555) | 954) | 1,086) | 818) | 907) | 1,088) | 1,079) | 1,129) | 1,106) | 1,450) | 2,232) | 1,572) | 1,680) | 1,725) | ||||||
| Sales | 6,554) | 6,265) | 5,951) | 6,838) | 6,053) | 5,936) | 5,741) | 6,538) | 5,798) | 5,743) | 5,796) | 6,405) | 5,624) | 5,912) | 5,949) | 8,369) | 7,663) | 7,751) | 7,688) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| Net profit margin1 | 16.91% | 15.95% | 14.89% | 14.71% | 14.43% | 14.21% | 15.81% | 16.33% | 16.39% | 17.83% | 18.54% | 19.94% | 22.89% | 22.80% | 23.32% | 22.91% | 21.65% | 20.61% | 21.32% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| Net Profit Margin, Competitors2 | |||||||||||||||||||||||||
| AbbVie Inc. | 15.67% | 9.80% | 5.79% | 6.91% | 4.00% | 6.45% | 7.31% | 7.59% | 9.22% | 9.71% | 11.02% | 8.95% | 11.81% | 15.50% | 13.37% | 20.39% | 23.19% | 22.04% | 22.00% | ||||||
| Amgen Inc. | 25.38% | 24.11% | 21.98% | 21.94% | 20.31% | 19.75% | 18.10% | 12.77% | 13.58% | 10.60% | 13.35% | 24.96% | 29.52% | 31.52% | 31.77% | 26.42% | 27.88% | 26.73% | 23.42% | ||||||
| Bristol-Myers Squibb Co. | 18.47% | 18.87% | 15.01% | 14.64% | 12.57% | 10.58% | 11.38% | -18.53% | -15.30% | -14.06% | -13.50% | 17.83% | 18.44% | 17.62% | 15.95% | 13.71% | 14.29% | 14.04% | 13.31% | ||||||
| Eli Lilly & Co. | 31.90% | 33.53% | 34.99% | 31.67% | 30.99% | 25.91% | 22.66% | 23.51% | 20.48% | 18.86% | 17.08% | 15.36% | 15.55% | 22.01% | 20.54% | 21.88% | 20.63% | 19.58% | 20.90% | ||||||
| Gilead Sciences Inc. | -12.56% | -10.86% | 31.51% | 29.43% | 28.41% | 21.98% | 20.87% | 1.68% | 0.45% | 3.82% | 1.78% | 21.03% | 21.60% | 20.18% | 20.87% | 17.02% | 12.44% | 15.22% | 16.60% | ||||||
| Johnson & Johnson | 16.20% | 21.48% | 21.83% | 28.46% | 27.26% | 25.00% | 24.41% | 15.84% | 16.74% | 43.91% | 44.92% | 41.28% | 39.58% | 14.52% | 13.77% | 18.90% | 19.95% | 19.21% | 20.90% | ||||||
| Merck & Co. Inc. | 3.64% | 4.77% | 13.59% | 28.08% | 29.63% | 25.79% | 27.27% | 26.68% | 19.23% | 21.98% | 3.76% | 0.61% | 7.77% | 5.34% | 22.52% | 24.49% | 25.88% | 29.00% | 26.27% | ||||||
| Pfizer Inc. | 6.34% | 6.80% | 11.83% | 12.42% | 15.65% | 16.84% | 12.62% | 12.62% | 7.04% | -4.62% | -0.55% | 3.56% | 15.13% | 27.38% | 31.19% | 31.27% | 29.81% | 28.94% | 27.01% | ||||||
| Regeneron Pharmaceuticals Inc. | 28.51% | 27.86% | 29.65% | 31.41% | 32.13% | 31.37% | 31.94% | 31.07% | 33.61% | 32.04% | 29.45% | 30.14% | 30.47% | 33.93% | 33.81% | 35.64% | 39.17% | 39.97% | 48.06% | ||||||
| Thermo Fisher Scientific Inc. | 14.94% | 15.04% | 15.15% | 15.05% | 15.02% | 15.23% | 15.18% | 14.77% | 14.48% | 14.69% | 14.20% | 13.99% | 13.68% | 13.14% | 13.75% | 15.47% | 15.92% | 17.37% | 18.49% | ||||||
| Vertex Pharmaceuticals Inc. | 30.70% | 35.00% | 35.51% | 32.94% | 31.35% | 31.86% | -8.91% | -4.86% | -4.52% | -4.74% | 39.46% | 36.68% | 35.94% | 35.40% | 35.40% | 37.20% | 37.62% | 38.26% | 30.84% | ||||||
Based on: 10-Q (reporting date: 2026-09-25), 10-Q (reporting date: 2026-06-26), 10-Q (reporting date: 2026-03-27), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-26), 10-Q (reporting date: 2025-06-27), 10-Q (reporting date: 2025-03-28), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-27), 10-Q (reporting date: 2024-06-28), 10-Q (reporting date: 2024-03-29), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-29), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-07-01), 10-Q (reporting date: 2022-04-01).
1 Q3 2026 Calculation
Net profit margin = 100
× (Net earningsQ3 2026
+ Net earningsQ2 2026
+ Net earningsQ1 2026
+ Net earningsQ4 2025)
÷ (SalesQ3 2026
+ SalesQ2 2026
+ SalesQ1 2026
+ SalesQ4 2025)
= 100 × (1,235 + 870 + 1,029 + 1,197)
÷ (6,554 + 6,265 + 5,951 + 6,838)
= 16.91%
2 Click competitor name to see calculations.
The net profit margin exhibited a distinct three-phase cycle between April 2022 and September 2026, characterized by initial stability, a significant period of contraction, and a subsequent gradual recovery.
- Initial Peak and Stability
- Between April 2022 and March 2023, the net profit margin remained robust, fluctuating between 20.61% and 23.32%. This period reached its apex in March 2023 at 23.32%, reflecting a period of peak operational efficiency relative to sales volume.
- Period of Margin Erosion
- A sustained downward trend commenced in mid-2023, with the margin falling below the 20% threshold by December 2023. This contraction continued through 2024 and early 2025, reaching a minimum of 14.21% in June 2025. This decline is notable as it occurred while sales figures remained relatively stable, suggesting a significant increase in operating expenses or a reduction in pricing power during this interval.
- Recovery Phase
- Starting in the second half of 2025, a consistent upward trajectory is observed. The net profit margin improved incrementally from 14.43% in June 2025 to 16.91% by September 2026. This recovery correlates with a general increase in net earnings, moving from a low of 555 million in June 2025 to 1,235 million by the end of the analyzed period.
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Return on Equity (ROE)
Danaher Corp., ROE calculation (quarterly data)
| Sep 25, 2026 | Jun 26, 2026 | Mar 27, 2026 | Dec 31, 2025 | Sep 26, 2025 | Jun 27, 2025 | Mar 28, 2025 | Dec 31, 2024 | Sep 27, 2024 | Jun 28, 2024 | Mar 29, 2024 | Dec 31, 2023 | Sep 29, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jul 1, 2022 | Apr 1, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Net earnings | 1,235) | 870) | 1,029) | 1,197) | 908) | 555) | 954) | 1,086) | 818) | 907) | 1,088) | 1,079) | 1,129) | 1,106) | 1,450) | 2,232) | 1,572) | 1,680) | 1,725) | ||||||
| Total Danaher stockholders’ equity | 53,621) | 52,581) | 52,949) | 52,534) | 51,071) | 52,334) | 50,849) | 49,543) | 51,299) | 49,897) | 53,442) | 53,486) | 52,407) | 51,716) | 51,478) | 50,082) | 46,985) | 46,594) | 46,356) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| ROE1 | 8.08% | 7.61% | 6.97% | 6.88% | 6.86% | 6.52% | 7.40% | 7.87% | 7.59% | 8.42% | 8.24% | 8.91% | 11.29% | 12.30% | 13.47% | 14.39% | 14.40% | 13.63% | 13.93% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| ROE, Competitors2 | |||||||||||||||||||||||||
| AbbVie Inc. | — | — | — | — | — | — | 295.42% | 128.66% | 84.91% | 78.77% | 74.85% | 46.94% | 53.86% | 67.50% | 57.14% | 68.60% | 83.83% | 86.24% | 76.64% | ||||||
| Amgen Inc. | 65.43% | 74.80% | 84.87% | 89.06% | 72.82% | 89.11% | 95.59% | 69.59% | 56.20% | 52.83% | 74.93% | 107.78% | 98.82% | 117.67% | 148.04% | 178.97% | 187.11% | 271.85% | 624.78% | ||||||
| Bristol-Myers Squibb Co. | 39.49% | 41.59% | 36.25% | 38.19% | 32.55% | 28.96% | 31.16% | -54.78% | -42.34% | -38.44% | -37.28% | 27.27% | 28.57% | 24.91% | 22.97% | 20.37% | 20.44% | 20.30% | 19.79% | ||||||
| Eli Lilly & Co. | 68.49% | 78.84% | 81.02% | 77.78% | 77.38% | 75.52% | 70.45% | 74.62% | 58.78% | 54.14% | 47.91% | 48.65% | 44.46% | 58.73% | 50.82% | 58.64% | 59.91% | 66.61% | 65.69% | ||||||
| Gilead Sciences Inc. | -29.62% | -27.39% | 39.19% | 37.48% | 37.65% | 32.08% | 31.13% | 2.48% | 0.69% | 5.77% | 2.77% | 24.81% | 26.33% | 25.92% | 26.59% | 21.62% | 15.82% | 20.44% | 22.66% | ||||||
| Johnson & Johnson | 19.74% | 24.76% | 25.92% | 32.87% | 31.69% | 28.88% | 27.92% | 19.68% | 20.93% | 53.14% | 54.95% | 51.11% | 48.61% | 17.37% | 17.95% | 23.36% | 25.68% | 24.05% | 26.54% | ||||||
| Merck & Co. Inc. | 5.46% | 7.57% | 19.48% | 34.70% | 36.71% | 33.49% | 36.07% | 36.96% | 27.30% | 31.52% | 5.71% | 0.97% | 11.17% | 8.04% | 27.82% | 31.57% | 34.32% | 38.34% | 34.68% | ||||||
| Pfizer Inc. | 4.53% | 5.09% | 8.31% | 8.99% | 10.59% | 12.12% | 8.73% | 9.11% | 4.61% | -2.96% | -0.33% | 2.38% | 10.81% | 21.68% | 28.77% | 32.79% | 32.14% | 33.61% | 30.29% | ||||||
| Regeneron Pharmaceuticals Inc. | 14.38% | 13.65% | 14.08% | 14.41% | 14.79% | 14.89% | 15.31% | 15.03% | 15.87% | 15.32% | 14.29% | 15.22% | 16.03% | 17.90% | 17.80% | 19.14% | 25.05% | 27.49% | 39.84% | ||||||
| Thermo Fisher Scientific Inc. | 12.91% | 13.23% | 13.19% | 12.55% | 12.88% | 13.03% | 13.19% | 12.78% | 12.52% | 13.12% | 13.26% | 12.83% | 13.11% | 13.08% | 14.26% | 15.80% | 16.15% | 17.59% | 18.56% | ||||||
| Vertex Pharmaceuticals Inc. | 19.02% | 21.76% | 22.41% | 21.18% | 21.22% | 21.18% | -5.99% | -3.26% | -3.07% | -3.32% | 21.67% | 20.59% | 21.01% | 21.75% | 22.59% | 23.88% | 25.12% | 26.77% | 22.47% | ||||||
Based on: 10-Q (reporting date: 2026-09-25), 10-Q (reporting date: 2026-06-26), 10-Q (reporting date: 2026-03-27), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-26), 10-Q (reporting date: 2025-06-27), 10-Q (reporting date: 2025-03-28), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-27), 10-Q (reporting date: 2024-06-28), 10-Q (reporting date: 2024-03-29), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-29), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-07-01), 10-Q (reporting date: 2022-04-01).
1 Q3 2026 Calculation
ROE = 100
× (Net earningsQ3 2026
+ Net earningsQ2 2026
+ Net earningsQ1 2026
+ Net earningsQ4 2025)
÷ Total Danaher stockholders’ equity
= 100 × (1,235 + 870 + 1,029 + 1,197)
÷ 53,621 = 8.08%
2 Click competitor name to see calculations.
The Return on Equity (ROE) exhibits a pronounced cyclical pattern characterized by an initial period of high efficiency, a multi-year contraction, and a subsequent gradual recovery between April 2022 and September 2026.
- Profitability and ROE Compression
- A significant downward trend in ROE is observed from September 2022, where it peaked at 14.40%, falling to a low of 6.52% by June 2025. This compression was primarily driven by a substantial decline in net earnings, which dropped from a high of 2,232 million USD in December 2022 to a trough of 555 million USD in June 2025.
- Equity Base Expansion
- The total stockholders' equity grew steadily during the first two years of the period, rising from 46,356 million USD in April 2022 to a peak of 53,486 million USD by December 2023. The simultaneous increase in the equity base and the decrease in net earnings during 2023 acted as a catalyst for the rapid decline in ROE, which fell from 13.47% in March 2023 to 8.91% by December 2023.
- Stabilization and Recovery Phase
- A recovery phase began in the second half of 2025. Net earnings showed a consistent upward trajectory after June 2025, increasing to 1,235 million USD by September 2026. With the equity base remaining relatively stable between 51,000 million USD and 53,600 million USD during this timeframe, the increase in net income led to a steady improvement in ROE, which climbed back to 8.08% by the end of the period.
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Return on Assets (ROA)
Danaher Corp., ROA calculation (quarterly data)
| Sep 25, 2026 | Jun 26, 2026 | Mar 27, 2026 | Dec 31, 2025 | Sep 26, 2025 | Jun 27, 2025 | Mar 28, 2025 | Dec 31, 2024 | Sep 27, 2024 | Jun 28, 2024 | Mar 29, 2024 | Dec 31, 2023 | Sep 29, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jul 1, 2022 | Apr 1, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Net earnings | 1,235) | 870) | 1,029) | 1,197) | 908) | 555) | 954) | 1,086) | 818) | 907) | 1,088) | 1,079) | 1,129) | 1,106) | 1,450) | 2,232) | 1,572) | 1,680) | 1,725) | ||||||
| Total assets | 93,281) | 92,367) | 83,544) | 83,464) | 79,897) | 81,620) | 79,116) | 77,542) | 80,615) | 78,555) | 83,402) | 84,488) | 87,734) | 84,902) | 85,040) | 84,350) | 81,030) | 81,806) | 83,392) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| ROA1 | 4.64% | 4.33% | 4.42% | 4.33% | 4.38% | 4.18% | 4.76% | 5.03% | 4.83% | 5.35% | 5.28% | 5.64% | 6.74% | 7.49% | 8.15% | 8.55% | 8.35% | 7.76% | 7.74% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| ROA, Competitors2 | |||||||||||||||||||||||||
| AbbVie Inc. | 7.00% | 4.67% | 2.66% | 3.15% | 1.78% | 2.74% | 3.08% | 3.17% | 3.57% | 3.76% | 4.03% | 3.61% | 4.78% | 6.42% | 5.64% | 8.53% | 9.49% | 8.83% | 8.71% | ||||||
| Amgen Inc. | 9.78% | 9.14% | 8.43% | 8.51% | 7.77% | 7.53% | 6.64% | 4.45% | 4.65% | 3.44% | 4.05% | 6.91% | 8.36% | 8.84% | 8.92% | 10.06% | 10.73% | 11.09% | 9.67% | ||||||
| Bristol-Myers Squibb Co. | 10.41% | 10.59% | 8.41% | 7.83% | 6.23% | 5.33% | 5.86% | -9.66% | -7.75% | -6.91% | -6.21% | 8.43% | 9.08% | 8.52% | 7.75% | 6.53% | 6.80% | 6.59% | 6.07% | ||||||
| Eli Lilly & Co. | 18.63% | 18.77% | 21.68% | 18.35% | 16.02% | 13.67% | 12.42% | 13.45% | 11.07% | 10.22% | 9.60% | 8.19% | 8.61% | 11.85% | 10.70% | 12.62% | 12.71% | 12.09% | 13.06% | ||||||
| Gilead Sciences Inc. | -7.51% | -6.56% | 16.38% | 14.42% | 13.86% | 11.33% | 10.57% | 0.81% | 0.23% | 1.97% | 0.86% | 9.12% | 9.42% | 8.80% | 9.02% | 7.27% | 5.33% | 6.58% | 7.16% | ||||||
| Johnson & Johnson | 8.15% | 10.46% | 10.47% | 13.46% | 13.03% | 11.72% | 11.26% | 7.81% | 8.24% | 20.99% | 22.37% | 20.98% | 20.85% | 6.81% | 6.49% | 9.57% | 10.94% | 10.33% | 11.12% | ||||||
| Merck & Co. Inc. | 1.85% | 2.44% | 6.94% | 13.34% | 14.69% | 13.96% | 15.14% | 14.62% | 10.34% | 12.20% | 2.18% | 0.34% | 4.32% | 2.98% | 12.09% | 13.30% | 14.25% | 15.48% | 13.29% | ||||||
| Pfizer Inc. | 1.97% | 2.15% | 3.61% | 3.73% | 4.71% | 5.22% | 3.79% | 3.76% | 1.94% | -1.20% | -0.14% | 0.94% | 4.87% | 9.75% | 14.85% | 15.91% | 15.32% | 15.01% | 13.58% | ||||||
| Regeneron Pharmaceuticals Inc. | 10.85% | 10.37% | 10.82% | 11.11% | 11.40% | 11.67% | 11.98% | 11.69% | 12.43% | 11.98% | 11.22% | 11.95% | 12.41% | 14.02% | 13.91% | 14.85% | 19.40% | 20.90% | 30.11% | ||||||
| Thermo Fisher Scientific Inc. | 6.19% | 6.16% | 6.05% | 6.08% | 6.38% | 6.50% | 6.58% | 6.51% | 6.11% | 6.32% | 6.21% | 6.07% | 6.12% | 6.08% | 6.36% | 7.15% | 7.77% | 8.21% | 8.20% | ||||||
| Vertex Pharmaceuticals Inc. | 12.15% | 16.06% | 16.38% | 15.42% | 14.78% | 15.13% | -4.32% | -2.38% | -2.16% | -2.43% | 16.81% | 15.92% | 15.97% | 16.54% | 17.18% | 18.30% | 19.59% | 20.50% | 17.19% | ||||||
Based on: 10-Q (reporting date: 2026-09-25), 10-Q (reporting date: 2026-06-26), 10-Q (reporting date: 2026-03-27), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-26), 10-Q (reporting date: 2025-06-27), 10-Q (reporting date: 2025-03-28), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-27), 10-Q (reporting date: 2024-06-28), 10-Q (reporting date: 2024-03-29), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-29), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-07-01), 10-Q (reporting date: 2022-04-01).
1 Q3 2026 Calculation
ROA = 100
× (Net earningsQ3 2026
+ Net earningsQ2 2026
+ Net earningsQ1 2026
+ Net earningsQ4 2025)
÷ Total assets
= 100 × (1,235 + 870 + 1,029 + 1,197)
÷ 93,281 = 4.64%
2 Click competitor name to see calculations.
The Return on Assets (ROA) exhibits a distinct downward trajectory over the analyzed period, transitioning from a peak in late 2022 to a lower, stabilized baseline by 2026. This decline is primarily driven by a contraction in net earnings relative to the asset base.
- Initial High-Performance Phase (2022)
- ROA peaked at 8.55% in December 2022, coinciding with the highest recorded quarterly net earnings of 2,232 million US dollars. During this period, asset utilization was at its most efficient, with the ratio consistently remaining above 7.7%.
- Period of Profitability Contraction (2023–2024)
- A sustained compression of ROA is observed starting in early 2023. The ratio declined from 8.15% in March 2023 to a low of 4.83% by September 2024. This trend mirrors a significant drop in quarterly net earnings, which fell from 1,450 million US dollars in March 2023 to 818 million US dollars in September 2024, while total assets remained relatively stable between 78 and 87 billion US dollars.
- Stabilization and Asset Expansion (2025–2026)
- From 2025 onward, ROA reached a floor, fluctuating within a narrow band between 4.18% and 4.64%. Notably, in 2026, total assets increased significantly, exceeding 93 billion US dollars by September 2026. Despite a moderate recovery in net earnings to 1,235 million US dollars in the final quarter, the ROA did not return to previous highs, indicating a lower equilibrium of asset productivity compared to the 2022 baseline.
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