Analysis of Profitability Ratios
Quarterly Data
Profitability ratios measure the company ability to generate profitable sales from its resources (assets).
Profitability Ratios (Summary)
AbbVie Inc., profitability ratios (quarterly data)
Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).
- Gross Profit Margin
- The gross profit margin showed a generally increasing trend from early 2021 through 2022, peaking near 70% by the end of 2022. However, it declined through most of 2023, reaching a low around 62%, before recovering and stabilizing near 70% again by late 2024 and early 2025. This pattern suggests fluctuating cost control or pricing power, with a notable dip in 2023 followed by a rebound.
- Operating Profit Margin
- Operating profit margin increased steadily from early 2021, peaking around 32-33% through late 2021 and parts of 2022. Thereafter, it declined through 2023 and hit a significant low by the end of that year. The margin partially recovered in 2024 but dropped sharply again approaching early 2025. This indicates volatility in operational efficiency or expense management, with periods of strong profitability followed by marked deterioration.
- Net Profit Margin
- Net profit margin rose consistently during 2021 and early 2022, reaching over 23% in late 2022. Subsequent quarters through 2023 showed a decline, with margins falling below 9%, and further declining gradually towards 4% by early 2025. This trend reflects increasing challenges in converting revenue into net earnings, possibly from higher costs, taxes, or other non-operating factors impacting net results.
- Return on Equity (ROE)
- ROE exhibited a strong upward trajectory from early 2021, with values rising from around 38% to above 80% by late 2022. Despite a downward correction in 2023, the metric rose sharply again, reaching an anomalously high level above 295% by mid-2025. The unusually high ROE values in the later periods may be influenced by factors such as changes in equity base or exceptional earnings, warranting further investigation for sustainability and normalcy of returns.
- Return on Assets (ROA)
- ROA increased through 2021 and 2022, peaking near 9.5%, then declined steadily from 2023 onward, falling below 2% by mid-2025. This decline suggests reduced overall asset efficiency or profitability from the company’s asset base over the latest periods, contrasting with earlier stronger performance.
Return on Sales
Return on Investment
Gross Profit Margin
AbbVie Inc., gross profit margin calculation (quarterly data)
| Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Gross margin | 10,472) | 11,077) | 9,341) | 10,706) | 10,248) | 10,260) | 8,216) | 8,597) | 7,442) | 9,625) | 8,239) | 10,951) | 9,790) | 10,413) | 9,486) | 10,566) | 9,952) | 9,436) | 8,797) | ||||||
| Net revenues | 15,776) | 15,423) | 13,343) | 15,102) | 14,460) | 14,462) | 12,310) | 14,301) | 13,927) | 13,865) | 12,225) | 15,121) | 14,812) | 14,583) | 13,538) | 14,886) | 14,342) | 13,959) | 13,010) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| Gross profit margin1 | 69.74% | 70.93% | 70.69% | 69.99% | 67.21% | 62.75% | 62.28% | 62.42% | 65.76% | 68.91% | 69.43% | 70.00% | 69.62% | 70.48% | 69.53% | 68.96% | 67.72% | 65.62% | 64.82% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| Gross Profit Margin, Competitors2 | |||||||||||||||||||||||||
| Amgen Inc. | 64.71% | 62.99% | 61.48% | 59.85% | 58.71% | 61.56% | 64.76% | 68.60% | 72.35% | 72.87% | 73.65% | 74.17% | 73.99% | 74.00% | 73.30% | 73.44% | 74.00% | 73.97% | 74.37% | ||||||
| Bristol-Myers Squibb Co. | 69.50% | 70.29% | 70.47% | 71.08% | 74.91% | 75.38% | 75.71% | 76.24% | 76.54% | 77.01% | 77.68% | 78.04% | 78.82% | 79.13% | 79.62% | 78.57% | 76.92% | 75.88% | 74.42% | ||||||
| Danaher Corp. | 59.53% | 59.66% | 59.74% | 59.50% | 59.37% | 59.27% | 58.39% | 58.74% | 58.77% | 59.17% | 60.22% | 60.21% | 60.65% | 60.77% | 60.77% | 60.95% | 60.44% | 59.24% | 57.60% | ||||||
| Eli Lilly & Co. | 83.03% | 82.64% | 81.70% | 81.31% | 80.91% | 80.75% | 80.16% | 79.25% | 78.67% | 77.77% | 77.67% | 76.77% | 75.61% | 75.98% | 74.40% | 74.18% | 74.85% | 74.27% | 75.88% | ||||||
| Gilead Sciences Inc. | 78.31% | 78.42% | 78.17% | 78.15% | 75.98% | 75.56% | 75.62% | 75.87% | 78.66% | 79.27% | 78.94% | 79.03% | 74.31% | 75.30% | 75.50% | 75.56% | 80.23% | 79.90% | 80.32% | ||||||
| Johnson & Johnson | 68.08% | 67.92% | 68.30% | 69.07% | 69.05% | 69.06% | 69.20% | 68.82% | 68.54% | 68.06% | 67.34% | 67.26% | 67.43% | 67.86% | 67.97% | 68.16% | 67.51% | 67.00% | 66.24% | ||||||
| Merck & Co. Inc. | 77.18% | 76.60% | 76.42% | 76.32% | 75.82% | 75.25% | 74.37% | 73.17% | 72.86% | 72.96% | 72.43% | 70.63% | 70.49% | 70.41% | 70.72% | 72.02% | 67.95% | 67.48% | 66.99% | ||||||
| Pfizer Inc. | 73.39% | 72.12% | 72.28% | 71.94% | 67.73% | 58.18% | 58.09% | 58.10% | 60.97% | 69.61% | 68.61% | 65.77% | 65.53% | 62.18% | 60.35% | 62.08% | 65.28% | 70.96% | 76.46% | ||||||
| Regeneron Pharmaceuticals Inc. | 85.39% | 85.57% | 85.79% | 86.13% | 86.12% | 86.16% | 86.32% | 86.16% | 85.96% | 86.42% | 86.96% | 87.18% | 85.39% | 84.97% | 84.65% | 84.83% | 86.65% | 86.85% | 86.84% | ||||||
| Thermo Fisher Scientific Inc. | 41.27% | 41.18% | 41.34% | 41.28% | 40.77% | 40.76% | 40.40% | 39.90% | 39.87% | 39.75% | 40.28% | 42.24% | 44.42% | 46.63% | 48.37% | 50.08% | 51.05% | 51.29% | 51.47% | ||||||
| Vertex Pharmaceuticals Inc. | 86.28% | 86.11% | 86.03% | 86.11% | 86.12% | 86.45% | 86.86% | 87.21% | 87.80% | 87.92% | 88.04% | 87.90% | 88.00% | 88.13% | 87.95% | 88.06% | 87.94% | 87.89% | 88.06% | ||||||
Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).
1 Q3 2025 Calculation
Gross profit margin = 100
× (Gross marginQ3 2025
+ Gross marginQ2 2025
+ Gross marginQ1 2025
+ Gross marginQ4 2024)
÷ (Net revenuesQ3 2025
+ Net revenuesQ2 2025
+ Net revenuesQ1 2025
+ Net revenuesQ4 2024)
= 100 × (10,472 + 11,077 + 9,341 + 10,706)
÷ (15,776 + 15,423 + 13,343 + 15,102)
= 69.74%
2 Click competitor name to see calculations.
The analysis of the financial trends over the reported periods reveals notable fluctuations and patterns across key metrics such as gross margin, net revenues, and gross profit margin.
- Gross Margin
- The gross margin in US$ millions demonstrates a cyclical pattern with periodic increases and declines. Starting at 8,797 million, it rises to a peak of approximately 10,951 million by the end of 2021, followed by a substantial drop during the first quarter of 2023, reaching as low as 7,442 million. Subsequent quarters reveal recovery and renewed growth, reaching over 11,000 million in mid-2025 before settling around 10,472 million in the last reported quarter. This volatility suggests sensitivity to seasonal factors or shifts in cost structures affecting the gross margin.
- Net Revenues
- Net revenues follow a similar trend as gross margin but with less pronounced volatility. Revenues increase steadily from 13,010 million in Q1 2021 to a high of approximately 15,121 million by Q4 2021. A decline is noted at the start of 2023, dropping to just above 12,000 million, yet revenues rebound quickly, eventually surpassing previous highs and reaching approximately 15,776 million by Q3 2025. This indicates overall growth in sales volume or pricing power despite short-term fluctuations.
- Gross Profit Margin (%)
- The gross profit margin percentage exhibits a gradually increasing trend from 64.82% in Q1 2021 to near 70% by late 2022, signaling improvements in cost efficiency or product mix. However, there is a notable dip to around 62% in early 2023, coinciding with the dip in gross margin and net revenues, potentially reflecting rising costs or pricing pressures. Recovery follows, with gross profit margin ascending back above 70% in later periods through 2024 and stabilizing near 70% into 2025. This suggests that the company was able to regain operational efficiencies or adjust pricing strategies positively after the mid-period dip.
Operating Profit Margin
AbbVie Inc., operating profit margin calculation (quarterly data)
| Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Operating earnings | 1,904) | 4,894) | 3,733) | (1,490) | 3,831) | 3,998) | 2,798) | 3,195) | 2,281) | 4,513) | 2,768) | 5,502) | 4,603) | 3,295) | 4,717) | 5,074) | 4,306) | 4,441) | 4,103) | ||||||
| Net revenues | 15,776) | 15,423) | 13,343) | 15,102) | 14,460) | 14,462) | 12,310) | 14,301) | 13,927) | 13,865) | 12,225) | 15,121) | 14,812) | 14,583) | 13,538) | 14,886) | 14,342) | 13,959) | 13,010) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| Operating profit margin1 | 15.16% | 18.80% | 17.56% | 16.22% | 24.89% | 22.31% | 23.50% | 23.49% | 27.32% | 31.03% | 28.49% | 31.21% | 30.59% | 30.33% | 32.68% | 31.89% | 30.09% | 28.95% | 23.63% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| Operating Profit Margin, Competitors2 | |||||||||||||||||||||||||
| Amgen Inc. | 25.14% | 24.45% | 22.71% | 22.66% | 19.97% | 20.96% | 24.72% | 29.35% | 34.55% | 37.50% | 36.07% | 38.57% | 39.31% | 38.04% | 32.78% | 31.44% | 30.14% | 30.72% | 37.23% | ||||||
| Bristol-Myers Squibb Co. | 18.86% | 16.70% | 15.24% | -15.50% | -14.05% | -14.39% | -14.30% | 16.18% | 16.96% | 17.29% | 18.13% | 17.96% | 19.04% | 18.19% | 16.79% | 15.91% | -15.73% | -17.02% | -19.19% | ||||||
| Danaher Corp. | 19.01% | 18.39% | 20.26% | 20.37% | 20.11% | 21.22% | 21.05% | 21.77% | 23.83% | 25.06% | 27.02% | 27.61% | 27.35% | 25.44% | 25.23% | 25.35% | 24.63% | 25.04% | 22.30% | ||||||
| Eli Lilly & Co. | 38.84% | 32.37% | 28.74% | 28.64% | 24.81% | 23.28% | 20.80% | 18.92% | 18.42% | 24.17% | 22.45% | 24.97% | 24.65% | 25.50% | 25.94% | 22.45% | 23.17% | 21.81% | 22.06% | ||||||
| Gilead Sciences Inc. | 36.75% | 28.03% | 28.77% | 5.81% | 2.92% | 9.26% | 5.79% | 28.24% | 30.37% | 31.18% | 33.03% | 27.17% | 22.39% | 25.78% | 26.56% | 36.72% | 42.79% | 37.20% | 18.07% | ||||||
| Johnson & Johnson | 25.44% | 23.67% | 23.59% | 23.42% | 24.42% | 25.31% | 25.04% | 24.90% | 25.55% | 25.61% | 25.21% | 24.63% | 23.89% | 23.47% | 23.76% | 24.95% | 24.69% | 25.23% | 24.10% | ||||||
| Merck & Co. Inc. | 33.73% | 30.00% | 31.51% | 31.03% | 21.60% | 24.75% | 6.93% | 3.92% | 13.08% | 10.34% | 27.85% | 30.27% | 30.66% | 33.04% | 28.85% | 25.74% | 14.07% | 10.64% | 14.02% | ||||||
| Pfizer Inc. | 21.85% | 23.23% | 19.29% | 19.51% | 9.56% | -4.19% | -2.08% | 2.15% | 14.36% | 28.13% | 34.44% | 34.83% | 33.59% | 30.37% | 26.12% | 23.91% | 24.67% | 24.12% | 21.20% | ||||||
| Regeneron Pharmaceuticals Inc. | 25.89% | 27.02% | 27.20% | 28.10% | 28.69% | 28.95% | 29.40% | 30.85% | 32.23% | 34.20% | 35.79% | 38.93% | 45.45% | 48.19% | 55.08% | 55.67% | 55.19% | 53.94% | 43.37% | ||||||
| Thermo Fisher Scientific Inc. | 17.16% | 17.13% | 17.23% | 17.11% | 16.93% | 17.01% | 16.38% | 16.00% | 15.81% | 15.42% | 16.29% | 18.69% | 20.54% | 22.51% | 23.83% | 25.57% | 27.04% | 28.00% | 27.68% | ||||||
| Vertex Pharmaceuticals Inc. | 34.06% | 34.36% | -6.69% | -2.11% | -2.54% | -3.37% | 41.16% | 38.83% | 40.16% | 41.72% | 43.93% | 48.23% | 47.72% | 48.85% | 36.93% | 36.73% | 37.17% | 33.93% | 47.14% | ||||||
Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).
1 Q3 2025 Calculation
Operating profit margin = 100
× (Operating earningsQ3 2025
+ Operating earningsQ2 2025
+ Operating earningsQ1 2025
+ Operating earningsQ4 2024)
÷ (Net revenuesQ3 2025
+ Net revenuesQ2 2025
+ Net revenuesQ1 2025
+ Net revenuesQ4 2024)
= 100 × (1,904 + 4,894 + 3,733 + -1,490)
÷ (15,776 + 15,423 + 13,343 + 15,102)
= 15.16%
2 Click competitor name to see calculations.
The financial data reveals several notable trends in the company's quarterly performance over the observed periods.
- Operating Earnings
- Operating earnings exhibit significant volatility throughout the periods. Starting at 4,103 million US dollars in the first quarter of 2021, earnings increased to a peak of 5,502 million by the end of 2021. However, the first half of 2022 showed a marked decline, notably dropping to 3,295 million in the second quarter. Recovery ensued in late 2022, with earnings rising again but followed by another sharp decrease in the early quarters of 2023, where earnings fell to as low as 2,281 million in Q3 2023. A partial recovery followed through 2024, but there was a considerable negative dip to -1,490 million in late 2024, indicating a potential significant loss during that quarter. Subsequent quarters saw a rebound, though figures remained inconsistent with substantial fluctuations through the latest quarter at 1,904 million.
- Net Revenues
- Net revenues show relatively steadier growth compared to operating earnings. The figures generally trend upward from 13,010 million in the first quarter of 2021 to 15,776 million by the third quarter of 2025. Despite minor quarter-to-quarter dips, such as in the first quarter of 2023 and early 2024, the overall revenue trend remains positive. The revenue growth is moderate and relatively stable, reflecting ongoing sales strength despite the volatility observed in operating earnings.
- Operating Profit Margin
- The operating profit margin reflects the variability observed in operating earnings. The margin improved in 2021, reaching over 31% by year-end. Entering 2022, it hovered around 30%, indicating relatively strong profitability. Yet, a decline is apparent beginning in late 2022 and continuing into 2023 and 2024, with the profit margin dropping below 25% and even further to the mid-teens by late 2024 and early 2025. The lowest recorded margin of approximately 15% corresponds with quarters showing depressed operating earnings, highlighting reduced operational efficiency or increased costs impacting profitability during these periods.
Overall, the data suggests that while revenue generation remains relatively robust and growing, operating earnings and profitability margins show marked volatility, with significant fluctuations and a notable downturn in some quarters. This indicates challenges in controlling operational costs or other factors affecting earnings despite steady revenue inflows. The recent quarters warrant close monitoring to understand the drivers of these volatility patterns and their implications on overall financial health.
Net Profit Margin
AbbVie Inc., net profit margin calculation (quarterly data)
| Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Net earnings (loss) attributable to AbbVie Inc. | 186) | 938) | 1,286) | (22) | 1,561) | 1,370) | 1,369) | 822) | 1,778) | 2,024) | 239) | 2,473) | 3,949) | 924) | 4,490) | 4,044) | 3,179) | 766) | 3,553) | ||||||
| Net revenues | 15,776) | 15,423) | 13,343) | 15,102) | 14,460) | 14,462) | 12,310) | 14,301) | 13,927) | 13,865) | 12,225) | 15,121) | 14,812) | 14,583) | 13,538) | 14,886) | 14,342) | 13,959) | 13,010) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| Net profit margin1 | 4.00% | 6.45% | 7.31% | 7.59% | 9.22% | 9.71% | 11.02% | 8.95% | 11.81% | 15.50% | 13.37% | 20.39% | 23.19% | 22.04% | 22.00% | 20.54% | 13.66% | 12.40% | 10.28% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| Net Profit Margin, Competitors2 | |||||||||||||||||||||||||
| Amgen Inc. | 20.31% | 19.75% | 18.10% | 12.77% | 13.58% | 10.60% | 13.35% | 24.96% | 29.52% | 31.52% | 31.77% | 26.42% | 27.88% | 26.73% | 23.42% | 24.25% | 23.03% | 23.80% | 29.60% | ||||||
| Bristol-Myers Squibb Co. | 12.57% | 10.58% | 11.38% | -18.53% | -15.30% | -14.06% | -13.50% | 17.83% | 18.44% | 17.62% | 15.95% | 13.71% | 14.29% | 14.04% | 13.31% | 15.08% | -11.89% | -11.44% | -14.53% | ||||||
| Danaher Corp. | 14.43% | 14.21% | 15.81% | 16.33% | 16.39% | 17.83% | 18.54% | 19.94% | 22.89% | 22.80% | 23.32% | 22.91% | 21.65% | 20.61% | 21.32% | 21.84% | 20.97% | 21.00% | 19.17% | ||||||
| Eli Lilly & Co. | 30.99% | 25.91% | 22.66% | 23.51% | 20.48% | 18.86% | 17.08% | 15.36% | 15.55% | 22.01% | 20.54% | 21.88% | 20.63% | 19.58% | 20.90% | 19.71% | 21.52% | 22.71% | 23.91% | ||||||
| Gilead Sciences Inc. | 28.41% | 21.98% | 20.87% | 1.68% | 0.45% | 3.82% | 1.78% | 21.03% | 21.60% | 20.18% | 20.87% | 17.02% | 12.44% | 15.22% | 16.60% | 23.05% | 27.21% | 19.62% | 1.19% | ||||||
| Johnson & Johnson | 27.26% | 25.00% | 24.41% | 15.84% | 16.74% | 43.91% | 44.92% | 41.28% | 39.58% | 14.52% | 13.77% | 18.90% | 19.95% | 19.21% | 20.90% | 22.26% | 19.55% | 19.92% | 17.95% | ||||||
| Merck & Co. Inc. | 29.63% | 25.79% | 27.27% | 26.68% | 19.23% | 21.98% | 3.76% | 0.61% | 7.77% | 5.34% | 22.52% | 24.49% | 25.88% | 29.00% | 26.27% | 26.79% | 15.09% | 11.83% | 15.09% | ||||||
| Pfizer Inc. | 15.65% | 16.84% | 12.62% | 12.62% | 7.04% | -4.62% | -0.55% | 3.56% | 15.13% | 27.38% | 31.19% | 31.27% | 29.81% | 28.94% | 27.01% | 27.04% | 28.77% | 23.86% | 24.03% | ||||||
| Regeneron Pharmaceuticals Inc. | 32.13% | 31.37% | 31.94% | 31.07% | 33.61% | 32.04% | 29.45% | 30.14% | 30.47% | 33.93% | 33.81% | 35.64% | 39.17% | 39.97% | 48.06% | 50.25% | 51.65% | 50.11% | 43.53% | ||||||
| Thermo Fisher Scientific Inc. | 15.02% | 15.23% | 15.18% | 14.77% | 14.48% | 14.69% | 14.20% | 13.99% | 13.68% | 13.14% | 13.75% | 15.47% | 15.92% | 17.37% | 18.49% | 19.70% | 21.93% | 22.47% | 22.08% | ||||||
| Vertex Pharmaceuticals Inc. | 31.35% | 31.86% | -8.91% | -4.86% | -4.52% | -4.74% | 39.46% | 36.68% | 35.94% | 35.40% | 35.40% | 37.20% | 37.62% | 38.26% | 30.84% | 30.92% | 30.52% | 29.80% | 43.06% | ||||||
Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).
1 Q3 2025 Calculation
Net profit margin = 100
× (Net earnings (loss) attributable to AbbVie Inc.Q3 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q2 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q1 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q4 2024)
÷ (Net revenuesQ3 2025
+ Net revenuesQ2 2025
+ Net revenuesQ1 2025
+ Net revenuesQ4 2024)
= 100 × (186 + 938 + 1,286 + -22)
÷ (15,776 + 15,423 + 13,343 + 15,102)
= 4.00%
2 Click competitor name to see calculations.
The financial analysis over the observed quarterly periods reveals several notable trends in the company's operational and profitability performance. The review focuses on net earnings, net revenues, and net profit margins to provide insights into overall business health and efficiency.
- Net Earnings
- Net earnings exhibit significant volatility throughout the quarters. Initial periods show relatively high earnings, peaking markedly in the fourth quarter of 2021, followed by a sharp decline in the subsequent quarters of 2022. The pattern continues with fluctuations, including a notable drop into negative territory in the fourth quarter of 2024. This fluctuation suggests irregular profit performance possibly due to varying operational costs, one-time charges, or market conditions affecting profitability.
- Net Revenues
- Net revenues demonstrate a generally stable and slightly increasing trend over the analyzed periods, with occasional dips. The revenue figures peak at the end of 2025, indicating a growth trajectory despite the earnings volatility. This steady revenue growth points to the company’s ability to maintain or expand its sales base despite operational challenges reflected in earnings volatility.
- Net Profit Margin
- The net profit margin displays considerable variation, with a peak in the latter part of 2021, reaching above 20%, corresponding with high net earnings at that time. However, starting in 2023, the margin trend shows a gradual decline, dropping down to just 4% by the first quarter of 2025. The decreasing margins imply rising costs, increasing competitive pressures, or other factors eroding profitability despite stable revenues.
In summary, while the company maintains stable and growing revenue streams, the ability to convert these revenues into net earnings has become increasingly challenging. The sharp fluctuations in net earnings alongside declining profit margins suggest that cost management, pricing strategies, or external economic factors may be constraining profitability. Moving forward, addressing these profitability challenges will be critical to sustaining long-term financial health.
Return on Equity (ROE)
AbbVie Inc., ROE calculation (quarterly data)
| Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Net earnings (loss) attributable to AbbVie Inc. | 186) | 938) | 1,286) | (22) | 1,561) | 1,370) | 1,369) | 822) | 1,778) | 2,024) | 239) | 2,473) | 3,949) | 924) | 4,490) | 4,044) | 3,179) | 766) | 3,553) | ||||||
| Stockholders’ equity (deficit) | (2,642) | (183) | 1,420) | 3,325) | 6,032) | 6,778) | 8,007) | 10,360) | 12,094) | 12,866) | 13,274) | 17,254) | 15,994) | 14,653) | 16,283) | 15,408) | 13,550) | 12,569) | 13,710) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| ROE1 | — | — | 295.42% | 128.66% | 84.91% | 78.77% | 74.85% | 46.94% | 53.86% | 67.50% | 57.14% | 68.60% | 83.83% | 86.24% | 76.64% | 74.91% | 55.60% | 53.01% | 37.63% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| ROE, Competitors2 | |||||||||||||||||||||||||
| Amgen Inc. | 72.82% | 89.11% | 95.59% | 69.59% | 56.20% | 52.83% | 74.93% | 107.78% | 98.82% | 117.67% | 148.04% | 178.97% | 187.11% | 271.85% | 624.78% | 87.96% | 68.26% | 69.67% | 75.91% | ||||||
| Bristol-Myers Squibb Co. | 32.55% | 28.96% | 31.16% | -54.78% | -42.34% | -38.44% | -37.28% | 27.27% | 28.57% | 24.91% | 22.97% | 20.37% | 20.44% | 20.30% | 19.79% | 19.46% | -14.52% | -13.80% | -16.54% | ||||||
| Danaher Corp. | 6.86% | 6.52% | 7.40% | 7.87% | 7.59% | 8.42% | 8.24% | 8.91% | 11.29% | 12.30% | 13.47% | 14.39% | 14.40% | 13.63% | 13.93% | 14.24% | 13.54% | 13.12% | 11.76% | ||||||
| Eli Lilly & Co. | 77.38% | 75.52% | 70.45% | 74.62% | 58.78% | 54.14% | 47.91% | 48.65% | 44.46% | 58.73% | 50.82% | 58.64% | 59.91% | 66.61% | 65.69% | 62.16% | 76.99% | 94.20% | 88.31% | ||||||
| Gilead Sciences Inc. | 37.65% | 32.08% | 31.13% | 2.48% | 0.69% | 5.77% | 2.77% | 24.81% | 26.33% | 25.92% | 26.59% | 21.62% | 15.82% | 20.44% | 22.66% | 29.55% | 34.44% | 26.20% | 1.59% | ||||||
| Johnson & Johnson | 31.69% | 28.88% | 27.92% | 19.68% | 20.93% | 53.14% | 54.95% | 51.11% | 48.61% | 17.37% | 17.95% | 23.36% | 25.68% | 24.05% | 26.54% | 28.20% | 25.44% | 25.53% | 22.96% | ||||||
| Merck & Co. Inc. | 36.71% | 33.49% | 36.07% | 36.96% | 27.30% | 31.52% | 5.71% | 0.97% | 11.17% | 8.04% | 27.82% | 31.57% | 34.32% | 38.34% | 34.68% | 34.17% | 20.10% | 16.73% | 26.08% | ||||||
| Pfizer Inc. | 10.59% | 12.12% | 8.73% | 9.11% | 4.61% | -2.96% | -0.33% | 2.38% | 10.81% | 21.68% | 28.77% | 32.79% | 32.14% | 33.61% | 30.29% | 28.47% | 26.28% | 18.86% | 16.23% | ||||||
| Regeneron Pharmaceuticals Inc. | 14.79% | 14.89% | 15.31% | 15.03% | 15.87% | 15.32% | 14.29% | 15.22% | 16.03% | 17.90% | 17.80% | 19.14% | 25.05% | 27.49% | 39.84% | 43.03% | 40.53% | 41.02% | 33.43% | ||||||
| Thermo Fisher Scientific Inc. | 12.88% | 13.03% | 13.19% | 12.78% | 12.52% | 13.12% | 13.26% | 12.83% | 13.11% | 13.08% | 14.26% | 15.80% | 16.15% | 17.59% | 18.56% | 18.94% | 22.13% | 23.32% | 22.60% | ||||||
| Vertex Pharmaceuticals Inc. | 21.22% | 21.18% | -5.99% | -3.26% | -3.07% | -3.32% | 21.67% | 20.59% | 21.01% | 21.75% | 22.59% | 23.88% | 25.12% | 26.77% | 22.47% | 23.19% | 22.83% | 21.66% | 30.76% | ||||||
Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).
1 Q3 2025 Calculation
ROE = 100
× (Net earnings (loss) attributable to AbbVie Inc.Q3 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q2 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q1 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q4 2024)
÷ Stockholders’ equity (deficit)
= 100 × (186 + 938 + 1,286 + -22)
÷ -2,642 = —
2 Click competitor name to see calculations.
The analysis of the quarterly financial data reveals several notable trends and fluctuations in the company's net earnings, stockholders' equity, and return on equity (ROE) over the examined periods.
- Net Earnings (Loss) Attributable to the Company (US$ in millions)
-
The net earnings exhibit significant volatility across the quarters. Initial data points show strong earnings with peaks, notably in March and December 2021 and March 2022, with values exceeding US$ 3 billion. However, the figures sharply decreased in some quarters such as June 2021, June 2022, and December 2023, indicating periods of reduced profitability or potential losses.
From the beginning of 2023 onwards, the net earnings show a general downward trend with heightened oscillations, including some quarters with substantially reduced earnings, such as March and December 2023 and March 2024. Towards the later periods, specifically in 2025, the net earnings shrink further with some quarters even showing a near break-even or loss position (e.g., December 2024 and September 2025).
- Stockholders’ Equity (Deficit) (US$ in millions)
-
Stockholders' equity reflects a declining pattern from March 2021 through June 2025. Initial quarters show moderate equity levels exceeding US$ 13 billion, with slight increases and fluctuations up to December 2022.
Starting in 2023, equity decreases noticeably; by March 2024, the equity drops below US$ 9 billion, and this downward trend continues dramatically toward a negative equity position by mid-2025.
This transition from positive equity to deficit status suggests an erosion of net assets potentially due to sustained losses, dividend payments, share repurchases, or other capital structure changes.
- Return on Equity (ROE) (%)
-
The ROE values exhibit considerable fluctuation across the periods. Beginning in 2021, ROE shows high and increasing returns, peaking close to or above 80% in several quarters through 2022.
However, from 2023 onward, the ROE becomes more unstable with notable peaks and troughs. Some quarters in 2024 and early 2025 indicate exceptionally high ROE values (above 100%), likely influenced by the decreasing denominator effect due to the shrinking or negative equity rather than operational profitability improvements.
The trend illustrates that ROE in later periods may not be a reliable indicator of operational efficiency, but possibly a reflection of equity erosion.
In summary, the company experienced strong earnings and equity positions early in the analyzed span, followed by increased volatility in profitability and a concerning decline in equity leading to deficit territory by 2025. ROE remains elevated but its interpretation requires caution due to the diminishing equity base. These patterns suggest challenges in sustaining earnings and maintaining capital strength over time.
Return on Assets (ROA)
AbbVie Inc., ROA calculation (quarterly data)
| Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | Dec 31, 2021 | Sep 30, 2021 | Jun 30, 2021 | Mar 31, 2021 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | |||||||||||||||||||||||||
| Net earnings (loss) attributable to AbbVie Inc. | 186) | 938) | 1,286) | (22) | 1,561) | 1,370) | 1,369) | 822) | 1,778) | 2,024) | 239) | 2,473) | 3,949) | 924) | 4,490) | 4,044) | 3,179) | 766) | 3,553) | ||||||
| Total assets | 133,898) | 137,182) | 136,165) | 135,161) | 143,422) | 141,937) | 148,874) | 134,711) | 136,221) | 135,367) | 134,544) | 138,805) | 141,325) | 143,186) | 143,211) | 146,529) | 148,858) | 147,972) | 150,501) | ||||||
| Profitability Ratio | |||||||||||||||||||||||||
| ROA1 | 1.78% | 2.74% | 3.08% | 3.17% | 3.57% | 3.76% | 4.03% | 3.61% | 4.78% | 6.42% | 5.64% | 8.53% | 9.49% | 8.83% | 8.71% | 7.88% | 5.06% | 4.50% | 3.43% | ||||||
| Benchmarks | |||||||||||||||||||||||||
| ROA, Competitors2 | |||||||||||||||||||||||||
| Amgen Inc. | 7.77% | 7.53% | 6.64% | 4.45% | 4.65% | 3.44% | 4.05% | 6.91% | 8.36% | 8.84% | 8.92% | 10.06% | 10.73% | 11.09% | 9.67% | 9.63% | 8.63% | 9.61% | 11.33% | ||||||
| Bristol-Myers Squibb Co. | 6.23% | 5.33% | 5.86% | -9.66% | -7.75% | -6.91% | -6.21% | 8.43% | 9.08% | 8.52% | 7.75% | 6.53% | 6.80% | 6.59% | 6.07% | 6.40% | -4.87% | -4.58% | -5.53% | ||||||
| Danaher Corp. | 4.38% | 4.18% | 4.76% | 5.03% | 4.83% | 5.35% | 5.28% | 5.64% | 6.74% | 7.49% | 8.15% | 8.55% | 8.35% | 7.76% | 7.74% | 7.73% | 7.13% | 7.19% | 6.30% | ||||||
| Eli Lilly & Co. | 16.02% | 13.67% | 12.42% | 13.45% | 11.07% | 10.22% | 9.60% | 8.19% | 8.61% | 11.85% | 10.70% | 12.62% | 12.71% | 12.09% | 13.06% | 11.44% | 12.39% | 12.70% | 13.01% | ||||||
| Gilead Sciences Inc. | 13.86% | 11.33% | 10.57% | 0.81% | 0.23% | 1.97% | 0.86% | 9.12% | 9.42% | 8.80% | 9.02% | 7.27% | 5.33% | 6.58% | 7.16% | 9.16% | 11.02% | 7.59% | 0.45% | ||||||
| Johnson & Johnson | 13.03% | 11.72% | 11.26% | 7.81% | 8.24% | 20.99% | 22.37% | 20.98% | 20.85% | 6.81% | 6.49% | 9.57% | 10.94% | 10.33% | 11.12% | 11.47% | 9.98% | 10.07% | 8.76% | ||||||
| Merck & Co. Inc. | 14.69% | 13.96% | 15.14% | 14.62% | 10.34% | 12.20% | 2.18% | 0.34% | 4.32% | 2.98% | 12.09% | 13.30% | 14.25% | 15.48% | 13.29% | 12.35% | 7.70% | 6.14% | 7.73% | ||||||
| Pfizer Inc. | 4.71% | 5.22% | 3.79% | 3.76% | 1.94% | -1.20% | -0.14% | 0.94% | 4.87% | 9.75% | 14.85% | 15.91% | 15.32% | 15.01% | 13.58% | 12.11% | 11.10% | 7.78% | 7.01% | ||||||
| Regeneron Pharmaceuticals Inc. | 11.40% | 11.67% | 11.98% | 11.69% | 12.43% | 11.98% | 11.22% | 11.95% | 12.41% | 14.02% | 13.91% | 14.85% | 19.40% | 20.90% | 30.11% | 31.75% | 29.55% | 28.88% | 22.53% | ||||||
| Thermo Fisher Scientific Inc. | 6.38% | 6.50% | 6.58% | 6.51% | 6.11% | 6.32% | 6.21% | 6.07% | 6.12% | 6.08% | 6.36% | 7.15% | 7.77% | 8.21% | 8.20% | 8.12% | 11.64% | 12.70% | 12.02% | ||||||
| Vertex Pharmaceuticals Inc. | 14.78% | 15.13% | -4.32% | -2.38% | -2.16% | -2.43% | 16.81% | 15.92% | 15.97% | 16.54% | 17.18% | 18.30% | 19.59% | 20.50% | 17.19% | 17.44% | 17.25% | 16.30% | 22.80% | ||||||
Based on: 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).
1 Q3 2025 Calculation
ROA = 100
× (Net earnings (loss) attributable to AbbVie Inc.Q3 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q2 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q1 2025
+ Net earnings (loss) attributable to AbbVie Inc.Q4 2024)
÷ Total assets
= 100 × (186 + 938 + 1,286 + -22)
÷ 133,898 = 1.78%
2 Click competitor name to see calculations.
- Net Earnings (Loss) Attributable to AbbVie Inc.
- The net earnings demonstrate considerable volatility across the quarters analyzed. Initial figures in 2021 show a sharp decline from 3,553 million US dollars in the first quarter to 766 million in the subsequent quarter, followed by fluctuations reaching highs above 4,000 million in the latter part of 2021. Moving into 2022 and 2023, earnings again display variability with peaks and troughs, notably dropping to negative or near-zero levels in several quarters, including a significant negative value at the close of 2024. The pattern suggests a period marked by inconsistent profitability with no clear upward or downward trend but punctuated by sharp earning dips and recoveries.
- Total Assets
- Total assets show a gradual downward trend from 150,501 million US dollars in the first quarter of 2021 to around 133,898 million by the third quarter of 2025. The asset base experienced a small rebound at the beginning of 2024, but overall, the assets have steadily declined over the period, indicating possible asset disposals, depreciation, or other reductions in the asset base consistent with company activity or market conditions.
- Return on Assets (ROA)
- Return on Assets (ROA) exhibits a peak during 2021 and early 2022, reaching near 9.5% around the third quarter of 2022. After this peak, ROA starts to decline progressively, finishing at approximately 1.78% by the third quarter of 2025. This declining trend in ROA indicates decreasing efficiency in asset utilization or profitability generated per unit of asset over the longer term despite short-term peaks.
- Overall Analysis
- The company’s financial performance over the observed timeframe features significant volatility in net earnings with sporadic high and low points but an overall decline in profitability ratios by the end of the period. Simultaneously, the asset base contracts gradually, revealing a potential strategic or operational shift. Return on Assets initially improves before diminishing sharply, underscoring challenges in maintaining asset profitability. These patterns suggest an environment of financial uncertainty or restructuring impacting both earnings stability and asset productivity.