Profitability ratios measure the company ability to generate profitable sales from its resources (assets).
Profitability Ratios (Summary)
Based on: 10-Q (reporting date: 2026-06-28), 10-Q (reporting date: 2026-03-29), 10-K (reporting date: 2025-12-28), 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-29), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03).
The financial performance exhibits a distinct dichotomy between stable operational efficiency and significant volatility in bottom-line profitability and investment returns. While core margins remain consistent, non-operating factors appear to have driven substantial fluctuations in net income and return metrics over the analyzed period.
- Gross Profit Margin
- A high degree of stability is maintained, with values fluctuating within a narrow band between 67.26% and 69.20%. A slight upward trend peaked in March 2024 at 69.20% before stabilizing around 67.9% by mid-2026, indicating consistent control over direct production costs and pricing strategies.
- Operating Profit Margin
- Operational efficiency remains resilient, generally fluctuating between 23% and 26%. A gradual improvement is observed from 2022 through late 2025, reaching a peak of 26.85% in December 2025. This suggests a steady ability to manage operating expenses relative to revenue growth.
- Net Profit Margin
- Significant volatility is observed in the net profit margin. Following a dip to 13.77% in April 2023, a substantial surge occurred between October 2023 and June 2024, where margins peaked at 44.92%. This was followed by a sharp correction to 15.84% by December 2024, before recovering to a range of 21% to 28% through 2025 and early 2026. The divergence between the stable operating margin and the volatile net margin suggests the influence of one-time non-operating gains or losses.
- Return on Equity (ROE)
- ROE closely mirrors the volatility of the net profit margin. Returns dropped to 17.37% in July 2023 before spiking to a high of 54.95% in March 2024. A subsequent decline brought ROE back to approximately 19.68% by December 2024, with a moderate recovery to 32.87% in December 2025 and a eventual settling around 24.76% by June 2026.
- Return on Assets (ROA)
- ROA demonstrates a similar pattern of instability, correlating with net income fluctuations. A low of 6.49% in April 2023 was followed by a peak of 22.37% in March 2024. Similar to ROE, a sharp decrease occurred in late 2024, reaching 7.81% in December, before returning to a more normalized range of 10% to 13% throughout 2025 and 2026.
Overall, the analysis indicates that while the underlying business operations are stable and predictably profitable, the net financial results are subject to periodic, large-scale adjustments that significantly impact shareholder returns and asset efficiency.
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Return on Sales
Return on Investment
Gross Profit Margin
| Jun 28, 2026 | Mar 29, 2026 | Dec 28, 2025 | Sep 28, 2025 | Jun 29, 2025 | Mar 30, 2025 | Dec 29, 2024 | Sep 29, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Oct 1, 2023 | Jul 2, 2023 | Apr 2, 2023 | Dec 31, 2022 | Oct 2, 2022 | Jul 3, 2022 | Apr 3, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Gross profit | 17,259) | 15,956) | 16,596) | 16,690) | 16,115) | 14,536) | 15,392) | 15,508) | 15,578) | 14,872) | 14,597) | 14,745) | 15,057) | 14,207) | 15,941) | 15,984) | 16,101) | 15,828) | ||||||
| Sales to customers | 25,310) | 24,062) | 24,564) | 23,993) | 23,743) | 21,893) | 22,520) | 22,471) | 22,447) | 21,383) | 21,395) | 21,351) | 21,519) | 20,894) | 23,706) | 23,791) | 24,020) | 23,426) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| Gross profit margin1 | 67.91% | 67.82% | 67.88% | 68.08% | 67.92% | 68.30% | 69.07% | 69.05% | 69.06% | 69.20% | 68.82% | 68.54% | 68.06% | 67.34% | 67.26% | 67.43% | 67.86% | 67.97% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Gross Profit Margin, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 71.48% | 70.68% | 70.24% | 69.74% | 70.93% | 70.69% | 69.99% | 67.21% | 62.75% | 62.28% | 62.42% | 65.76% | 68.91% | 69.43% | 70.00% | 69.62% | 70.48% | 69.53% | ||||||
| Amgen Inc. | 67.97% | 66.72% | 65.75% | 64.71% | 62.99% | 61.48% | 59.85% | 58.71% | 61.56% | 64.76% | 68.60% | 72.35% | 72.87% | 73.65% | 74.17% | 73.99% | 74.00% | 73.30% | ||||||
| Bristol-Myers Squibb Co. | 70.16% | 70.46% | 71.08% | 69.50% | 70.29% | 70.47% | 71.08% | 74.91% | 75.38% | 75.71% | 76.24% | 76.54% | 77.01% | 77.68% | 78.04% | 78.82% | 79.13% | 79.62% | ||||||
| Danaher Corp. | 58.51% | 58.94% | 59.11% | 59.53% | 59.66% | 59.74% | 59.50% | 59.37% | 59.27% | 58.39% | 58.74% | 58.77% | 59.17% | 60.22% | 60.21% | 60.65% | 60.77% | 60.77% | ||||||
| Eli Lilly & Co. | 83.40% | 82.83% | 83.04% | 83.03% | 82.64% | 81.70% | 81.31% | 80.91% | 80.75% | 80.16% | 79.25% | 78.67% | 77.77% | 77.67% | 76.77% | 75.61% | 75.98% | 74.40% | ||||||
| Gilead Sciences Inc. | 79.15% | 79.01% | 78.44% | 78.31% | 78.42% | 78.17% | 78.15% | 75.98% | 75.56% | 75.62% | 75.87% | 78.66% | 79.27% | 78.94% | 79.03% | 74.31% | 75.30% | 75.50% | ||||||
| Merck & Co. Inc. | 72.97% | 73.91% | 74.80% | 77.18% | 76.60% | 76.42% | 76.32% | 75.82% | 75.25% | 74.37% | 73.17% | 72.86% | 72.96% | 72.43% | 70.63% | 70.49% | 70.41% | 70.72% | ||||||
| Pfizer Inc. | 73.18% | 73.51% | 74.33% | 73.39% | 72.12% | 72.28% | 71.94% | 67.73% | 58.18% | 58.09% | 58.10% | 60.97% | 69.61% | 68.61% | 65.77% | 65.53% | 62.18% | 60.35% | ||||||
| Regeneron Pharmaceuticals Inc. | 84.86% | 84.55% | 85.35% | 85.39% | 85.57% | 85.79% | 86.13% | 86.12% | 86.16% | 86.32% | 86.16% | 85.96% | 86.42% | 86.96% | 87.18% | 85.39% | 84.97% | 84.65% | ||||||
| Thermo Fisher Scientific Inc. | 40.80% | 40.78% | 40.93% | 41.27% | 41.18% | 41.34% | 41.28% | 40.77% | 40.76% | 40.40% | 39.90% | 39.87% | 39.75% | 40.28% | 42.24% | 44.42% | 46.63% | 48.37% | ||||||
| Vertex Pharmaceuticals Inc. | 86.00% | 86.24% | 86.24% | 86.28% | 86.11% | 86.03% | 86.11% | 86.12% | 86.45% | 86.86% | 87.21% | 87.80% | 87.92% | 88.04% | 87.90% | 88.00% | 88.13% | 87.95% | ||||||
Based on: 10-Q (reporting date: 2026-06-28), 10-Q (reporting date: 2026-03-29), 10-K (reporting date: 2025-12-28), 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-29), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03).
1 Q2 2026 Calculation
Gross profit margin = 100
× (Gross profitQ2 2026
+ Gross profitQ1 2026
+ Gross profitQ4 2025
+ Gross profitQ3 2025)
÷ (Sales to customersQ2 2026
+ Sales to customersQ1 2026
+ Sales to customersQ4 2025
+ Sales to customersQ3 2025)
= 100 × (17,259 + 15,956 + 16,596 + 16,690)
÷ (25,310 + 24,062 + 24,564 + 23,993)
= 67.91%
2 Click competitor name to see calculations.
The analysis of the gross profit margin reveals a period of relative stability characterized by a mid-term expansion followed by a return to baseline levels. Despite fluctuations in total sales and absolute gross profit, the margin remained within a tight range between 67.26% and 69.20% throughout the observed period.
- Margin Compression and Initial Decline (2022)
- A gradual downward trend in the gross profit margin was observed throughout 2022, starting at 67.97% in April and reaching a low of 67.26% by December. This period was marked by relatively high sales volumes, yet the efficiency of converting those sales into gross profit slightly diminished.
- Margin Expansion and Peak Performance (2023 - Early 2024)
- Beginning in April 2023, a consistent upward trajectory in the gross profit margin occurred. Notably, this expansion took place while sales to customers had decreased from 2022 levels, suggesting improved cost management or a shift toward higher-margin product mixes. The margin reached its peak of 69.20% in March 2024.
- Stabilization and Normalization (Mid-2024 - 2026)
- Following the peak in early 2024, the gross profit margin underwent a period of stabilization. A slight correction occurred in March 2025, with the margin dropping to 68.30%. For the remainder of the period, ending in June 2026, the margin converged and stabilized around the 67.8% to 67.9% range, effectively returning to the levels seen at the start of the analysis period.
- Relationship Between Sales Volume and Profitability
- There is a notable divergence between sales volume and margin percentage during the 2023 recovery phase. While sales experienced a significant dip in early 2023, the gross profit margin expanded, indicating that profitability per unit increased even as total volume decreased. Conversely, the subsequent growth in sales through 2025 and 2026 coincided with a normalization of the margin, suggesting that scale was regained without further increasing the percentage of gross profitability.
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Operating Profit Margin
| Jun 28, 2026 | Mar 29, 2026 | Dec 28, 2025 | Sep 28, 2025 | Jun 29, 2025 | Mar 30, 2025 | Dec 29, 2024 | Sep 29, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Oct 1, 2023 | Jul 2, 2023 | Apr 2, 2023 | Dec 31, 2022 | Oct 2, 2022 | Jul 3, 2022 | Apr 3, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Operating earnings | 7,140) | 6,327) | 5,426) | 7,033) | 6,646) | 6,182) | 3,582) | 5,037) | 6,276) | 5,909) | 4,193) | 5,534) | 5,813) | 5,667) | 5,331) | 6,216) | 6,087) | 5,748) | ||||||
| Sales to customers | 25,310) | 24,062) | 24,564) | 23,993) | 23,743) | 21,893) | 22,520) | 22,471) | 22,447) | 21,383) | 21,395) | 21,351) | 21,519) | 20,894) | 23,706) | 23,791) | 24,020) | 23,426) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| Operating profit margin1 | 26.47% | 26.39% | 26.85% | 25.44% | 23.67% | 23.59% | 23.42% | 24.42% | 25.31% | 25.04% | 24.90% | 25.55% | 25.61% | 25.21% | 24.63% | 23.89% | 23.47% | 23.76% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Operating Profit Margin, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 26.20% | 24.41% | 24.65% | 15.16% | 18.80% | 17.56% | 16.22% | 24.89% | 22.31% | 23.50% | 23.49% | 27.32% | 31.03% | 28.49% | 31.21% | 30.59% | 30.33% | 32.68% | ||||||
| Amgen Inc. | 31.51% | 29.77% | 25.83% | 25.14% | 24.45% | 22.71% | 22.66% | 19.97% | 20.96% | 24.72% | 29.35% | 34.55% | 37.50% | 36.07% | 38.57% | 39.31% | 38.04% | 32.78% | ||||||
| Bristol-Myers Squibb Co. | 23.83% | 20.55% | 20.75% | 18.86% | 16.70% | 15.24% | -15.50% | -14.05% | -14.39% | -14.30% | 16.18% | 16.96% | 17.29% | 18.13% | 17.96% | 19.04% | 18.19% | 16.79% | ||||||
| Danaher Corp. | 20.42% | 19.21% | 19.09% | 19.01% | 18.39% | 20.26% | 20.37% | 20.11% | 21.22% | 21.05% | 21.77% | 23.83% | 25.06% | 27.02% | 27.61% | 27.35% | 25.44% | 25.23% | ||||||
| Eli Lilly & Co. | 42.22% | 43.63% | 40.35% | 38.84% | 32.37% | 28.74% | 28.64% | 24.81% | 23.28% | 20.80% | 18.92% | 18.42% | 24.17% | 22.45% | 24.97% | 24.65% | 25.50% | 25.94% | ||||||
| Gilead Sciences Inc. | -8.37% | 35.46% | 34.66% | 36.75% | 28.03% | 28.77% | 5.81% | 2.92% | 9.26% | 5.79% | 28.24% | 30.37% | 31.18% | 33.03% | 27.17% | 22.39% | 25.78% | 26.56% | ||||||
| Merck & Co. Inc. | 9.58% | 18.18% | 32.64% | 33.73% | 30.00% | 31.51% | 31.03% | 21.60% | 24.75% | 6.93% | 3.92% | 13.08% | 10.34% | 27.85% | 30.27% | 30.66% | 33.04% | 28.85% | ||||||
| Pfizer Inc. | 21.70% | 22.96% | 22.76% | 21.85% | 23.23% | 19.29% | 19.51% | 9.56% | -4.19% | -2.08% | 2.15% | 14.36% | 28.13% | 34.44% | 34.83% | 33.59% | 30.37% | 26.12% | ||||||
| Regeneron Pharmaceuticals Inc. | 24.74% | 24.32% | 24.95% | 25.89% | 27.02% | 27.20% | 28.10% | 28.69% | 28.95% | 29.40% | 30.85% | 32.23% | 34.20% | 35.79% | 38.93% | 45.45% | 48.19% | 55.08% | ||||||
| Thermo Fisher Scientific Inc. | 17.58% | 17.46% | 17.38% | 17.16% | 17.13% | 17.23% | 17.11% | 16.93% | 17.01% | 16.38% | 16.00% | 15.81% | 15.42% | 16.29% | 18.69% | 20.54% | 22.51% | 23.83% | ||||||
| Vertex Pharmaceuticals Inc. | 37.95% | 38.31% | 34.77% | 34.06% | 34.36% | -6.69% | -2.11% | -2.54% | -3.37% | 41.16% | 38.83% | 40.16% | 41.72% | 43.93% | 48.23% | 47.72% | 48.85% | 36.93% | ||||||
Based on: 10-Q (reporting date: 2026-06-28), 10-Q (reporting date: 2026-03-29), 10-K (reporting date: 2025-12-28), 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-29), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03).
1 Q2 2026 Calculation
Operating profit margin = 100
× (Operating earningsQ2 2026
+ Operating earningsQ1 2026
+ Operating earningsQ4 2025
+ Operating earningsQ3 2025)
÷ (Sales to customersQ2 2026
+ Sales to customersQ1 2026
+ Sales to customersQ4 2025
+ Sales to customersQ3 2025)
= 100 × (7,140 + 6,327 + 5,426 + 7,033)
÷ (25,310 + 24,062 + 24,564 + 23,993)
= 26.47%
2 Click competitor name to see calculations.
The operating profit margin exhibits a cyclical pattern characterized by an initial growth phase, a mid-term contraction, and a subsequent strong recovery, ultimately ending at a higher efficiency level than the beginning of the observed period.
- Initial Margin Expansion (April 2022 – July 2023)
- A steady upward trend is observed during this period, with the operating profit margin increasing from 23.76% to a peak of 25.61%. This growth was driven by operating earnings rising from 5,748 million to 5,813 million, even as sales shifted from 23,426 million to 21,519 million, suggesting improved cost management or a shift toward higher-margin product mixes.
- Margin Compression and Volatility (October 2023 – December 2024)
- A period of decline is evident, with the margin retreating from 25.55% in October 2023 to a low of 23.42% by December 2024. This compression is most pronounced in the latter half of 2024, where operating earnings fell to 3,582 million despite sales remaining stable at 22,520 million, indicating a temporary increase in operating expenses or a reduction in pricing power.
- Recovery and Peak Performance (March 2025 – June 2026)
- A significant recovery is noted starting in March 2025, as margins climbed back above 23% and continued to expand. The efficiency peaked in December 2025 at 26.85%, the highest level in the dataset. This trend is sustained through June 2026, ending at 26.47%, supported by operating earnings reaching their highest recorded value of 7,140 million against sales of 25,310 million.
- Correlation between Sales and Earnings
- The data reveals that profit margins did not move in direct linear correlation with sales volume. For instance, the period between June 2024 and December 2024 saw sales increase slightly while operating earnings dropped sharply, leading to margin erosion. Conversely, the period from March 2025 to June 2026 shows both sales and operating earnings increasing concurrently, resulting in a reinforced and expanded operating margin.
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Net Profit Margin
| Jun 28, 2026 | Mar 29, 2026 | Dec 28, 2025 | Sep 28, 2025 | Jun 29, 2025 | Mar 30, 2025 | Dec 29, 2024 | Sep 29, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Oct 1, 2023 | Jul 2, 2023 | Apr 2, 2023 | Dec 31, 2022 | Oct 2, 2022 | Jul 3, 2022 | Apr 3, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Net earnings (loss) | 5,534) | 5,235) | 5,116) | 5,152) | 5,537) | 10,999) | 3,431) | 2,694) | 4,686) | 3,255) | 4,049) | 26,028) | 5,144) | (68) | 3,520) | 4,458) | 4,814) | 5,149) | ||||||
| Sales to customers | 25,310) | 24,062) | 24,564) | 23,993) | 23,743) | 21,893) | 22,520) | 22,471) | 22,447) | 21,383) | 21,395) | 21,351) | 21,519) | 20,894) | 23,706) | 23,791) | 24,020) | 23,426) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| Net profit margin1 | 21.48% | 21.83% | 28.46% | 27.26% | 25.00% | 24.41% | 15.84% | 16.74% | 43.91% | 44.92% | 41.28% | 39.58% | 14.52% | 13.77% | 18.90% | 19.95% | 19.21% | 20.90% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Net Profit Margin, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 9.80% | 5.79% | 6.91% | 4.00% | 6.45% | 7.31% | 7.59% | 9.22% | 9.71% | 11.02% | 8.95% | 11.81% | 15.50% | 13.37% | 20.39% | 23.19% | 22.04% | 22.00% | ||||||
| Amgen Inc. | 24.11% | 21.98% | 21.94% | 20.31% | 19.75% | 18.10% | 12.77% | 13.58% | 10.60% | 13.35% | 24.96% | 29.52% | 31.52% | 31.77% | 26.42% | 27.88% | 26.73% | 23.42% | ||||||
| Bristol-Myers Squibb Co. | 18.87% | 15.01% | 14.64% | 12.57% | 10.58% | 11.38% | -18.53% | -15.30% | -14.06% | -13.50% | 17.83% | 18.44% | 17.62% | 15.95% | 13.71% | 14.29% | 14.04% | 13.31% | ||||||
| Danaher Corp. | 15.95% | 14.89% | 14.71% | 14.43% | 14.21% | 15.81% | 16.33% | 16.39% | 17.83% | 18.54% | 19.94% | 22.89% | 22.80% | 23.32% | 22.91% | 21.65% | 20.61% | 21.32% | ||||||
| Eli Lilly & Co. | 33.53% | 34.99% | 31.67% | 30.99% | 25.91% | 22.66% | 23.51% | 20.48% | 18.86% | 17.08% | 15.36% | 15.55% | 22.01% | 20.54% | 21.88% | 20.63% | 19.58% | 20.90% | ||||||
| Gilead Sciences Inc. | -10.86% | 31.51% | 29.43% | 28.41% | 21.98% | 20.87% | 1.68% | 0.45% | 3.82% | 1.78% | 21.03% | 21.60% | 20.18% | 20.87% | 17.02% | 12.44% | 15.22% | 16.60% | ||||||
| Merck & Co. Inc. | 4.77% | 13.59% | 28.08% | 29.63% | 25.79% | 27.27% | 26.68% | 19.23% | 21.98% | 3.76% | 0.61% | 7.77% | 5.34% | 22.52% | 24.49% | 25.88% | 29.00% | 26.27% | ||||||
| Pfizer Inc. | 6.80% | 11.83% | 12.42% | 15.65% | 16.84% | 12.62% | 12.62% | 7.04% | -4.62% | -0.55% | 3.56% | 15.13% | 27.38% | 31.19% | 31.27% | 29.81% | 28.94% | 27.01% | ||||||
| Regeneron Pharmaceuticals Inc. | 27.86% | 29.65% | 31.41% | 32.13% | 31.37% | 31.94% | 31.07% | 33.61% | 32.04% | 29.45% | 30.14% | 30.47% | 33.93% | 33.81% | 35.64% | 39.17% | 39.97% | 48.06% | ||||||
| Thermo Fisher Scientific Inc. | 15.04% | 15.15% | 15.05% | 15.02% | 15.23% | 15.18% | 14.77% | 14.48% | 14.69% | 14.20% | 13.99% | 13.68% | 13.14% | 13.75% | 15.47% | 15.92% | 17.37% | 18.49% | ||||||
| Vertex Pharmaceuticals Inc. | 35.00% | 35.51% | 32.94% | 31.35% | 31.86% | -8.91% | -4.86% | -4.52% | -4.74% | 39.46% | 36.68% | 35.94% | 35.40% | 35.40% | 37.20% | 37.62% | 38.26% | 30.84% | ||||||
Based on: 10-Q (reporting date: 2026-06-28), 10-Q (reporting date: 2026-03-29), 10-K (reporting date: 2025-12-28), 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-29), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03).
1 Q2 2026 Calculation
Net profit margin = 100
× (Net earnings (loss)Q2 2026
+ Net earnings (loss)Q1 2026
+ Net earnings (loss)Q4 2025
+ Net earnings (loss)Q3 2025)
÷ (Sales to customersQ2 2026
+ Sales to customersQ1 2026
+ Sales to customersQ4 2025
+ Sales to customersQ3 2025)
= 100 × (5,534 + 5,235 + 5,116 + 5,152)
÷ (25,310 + 24,062 + 24,564 + 23,993)
= 21.48%
2 Click competitor name to see calculations.
The analysis of profitability indicates a period of extreme volatility in net profit margins, contrasting with a relatively stable revenue stream. While sales to customers exhibited a gradual upward trajectory from approximately 20.9 billion USD in early 2023 to 25.3 billion USD by mid-2026, net earnings and corresponding profit margins experienced significant fluctuations.
- Margin Volatility and Peak Performance
- A period of exceptional profitability is observed between October 2023 and March 2024, during which the net profit margin ascended from 39.58% to a peak of 44.92%. This surge coincides with a substantial increase in net earnings, suggesting the impact of non-recurring gains or extraordinary financial events rather than organic operational growth, given the lack of a proportional increase in sales during this window.
- Correction and Recovery Phases
- Following the peak, a sharp correction occurred in mid-2024, with the net profit margin descending to 15.84% by December 2024. A subsequent recovery phase is evident throughout 2025, where margins climbed steadily from 24.41% in March to 28.46% in December, reflecting an improvement in earnings efficiency.
- Long-term Stability Trends
- The data concludes with a stabilizing trend in the first half of 2026, with the net profit margin moderating to approximately 21.5%. This aligns more closely with the baseline margins observed in 2022, suggesting a return to normalized profitability levels after several quarters of high variance.
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Return on Equity (ROE)
| Jun 28, 2026 | Mar 29, 2026 | Dec 28, 2025 | Sep 28, 2025 | Jun 29, 2025 | Mar 30, 2025 | Dec 29, 2024 | Sep 29, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Oct 1, 2023 | Jul 2, 2023 | Apr 2, 2023 | Dec 31, 2022 | Oct 2, 2022 | Jul 3, 2022 | Apr 3, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Net earnings (loss) | 5,534) | 5,235) | 5,116) | 5,152) | 5,537) | 10,999) | 3,431) | 2,694) | 4,686) | 3,255) | 4,049) | 26,028) | 5,144) | (68) | 3,520) | 4,458) | 4,814) | 5,149) | ||||||
| Total Johnson & Johnson shareholders’ equity | 84,971) | 81,186) | 81,544) | 79,277) | 78,473) | 78,109) | 71,490) | 70,158) | 71,538) | 70,020) | 68,774) | 71,228) | 75,149) | 70,869) | 76,804) | 74,599) | 76,357) | 74,709) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| ROE1 | 24.76% | 25.92% | 32.87% | 31.69% | 28.88% | 27.92% | 19.68% | 20.93% | 53.14% | 54.95% | 51.11% | 48.61% | 17.37% | 17.95% | 23.36% | 25.68% | 24.05% | 26.54% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| ROE, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | — | — | — | — | — | 295.42% | 128.66% | 84.91% | 78.77% | 74.85% | 46.94% | 53.86% | 67.50% | 57.14% | 68.60% | 83.83% | 86.24% | 76.64% | ||||||
| Amgen Inc. | 74.80% | 84.87% | 89.06% | 72.82% | 89.11% | 95.59% | 69.59% | 56.20% | 52.83% | 74.93% | 107.78% | 98.82% | 117.67% | 148.04% | 178.97% | 187.11% | 271.85% | 624.78% | ||||||
| Bristol-Myers Squibb Co. | 41.59% | 36.25% | 38.19% | 32.55% | 28.96% | 31.16% | -54.78% | -42.34% | -38.44% | -37.28% | 27.27% | 28.57% | 24.91% | 22.97% | 20.37% | 20.44% | 20.30% | 19.79% | ||||||
| Danaher Corp. | 7.61% | 6.97% | 6.88% | 6.86% | 6.52% | 7.40% | 7.87% | 7.59% | 8.42% | 8.24% | 8.91% | 11.29% | 12.30% | 13.47% | 14.39% | 14.40% | 13.63% | 13.93% | ||||||
| Eli Lilly & Co. | 78.84% | 81.02% | 77.78% | 77.38% | 75.52% | 70.45% | 74.62% | 58.78% | 54.14% | 47.91% | 48.65% | 44.46% | 58.73% | 50.82% | 58.64% | 59.91% | 66.61% | 65.69% | ||||||
| Gilead Sciences Inc. | -27.39% | 39.19% | 37.48% | 37.65% | 32.08% | 31.13% | 2.48% | 0.69% | 5.77% | 2.77% | 24.81% | 26.33% | 25.92% | 26.59% | 21.62% | 15.82% | 20.44% | 22.66% | ||||||
| Merck & Co. Inc. | 7.57% | 19.48% | 34.70% | 36.71% | 33.49% | 36.07% | 36.96% | 27.30% | 31.52% | 5.71% | 0.97% | 11.17% | 8.04% | 27.82% | 31.57% | 34.32% | 38.34% | 34.68% | ||||||
| Pfizer Inc. | 5.09% | 8.31% | 8.99% | 10.59% | 12.12% | 8.73% | 9.11% | 4.61% | -2.96% | -0.33% | 2.38% | 10.81% | 21.68% | 28.77% | 32.79% | 32.14% | 33.61% | 30.29% | ||||||
| Regeneron Pharmaceuticals Inc. | 13.65% | 14.08% | 14.41% | 14.79% | 14.89% | 15.31% | 15.03% | 15.87% | 15.32% | 14.29% | 15.22% | 16.03% | 17.90% | 17.80% | 19.14% | 25.05% | 27.49% | 39.84% | ||||||
| Thermo Fisher Scientific Inc. | 13.23% | 13.19% | 12.55% | 12.88% | 13.03% | 13.19% | 12.78% | 12.52% | 13.12% | 13.26% | 12.83% | 13.11% | 13.08% | 14.26% | 15.80% | 16.15% | 17.59% | 18.56% | ||||||
| Vertex Pharmaceuticals Inc. | 21.76% | 22.41% | 21.18% | 21.22% | 21.18% | -5.99% | -3.26% | -3.07% | -3.32% | 21.67% | 20.59% | 21.01% | 21.75% | 22.59% | 23.88% | 25.12% | 26.77% | 22.47% | ||||||
Based on: 10-Q (reporting date: 2026-06-28), 10-Q (reporting date: 2026-03-29), 10-K (reporting date: 2025-12-28), 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-29), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03).
1 Q2 2026 Calculation
ROE = 100
× (Net earnings (loss)Q2 2026
+ Net earnings (loss)Q1 2026
+ Net earnings (loss)Q4 2025
+ Net earnings (loss)Q3 2025)
÷ Total Johnson & Johnson shareholders’ equity
= 100 × (5,534 + 5,235 + 5,116 + 5,152)
÷ 84,971 = 24.76%
2 Click competitor name to see calculations.
The analysis of Return on Equity (ROE) reveals a period of substantial volatility driven primarily by fluctuations in net earnings rather than consistent changes in the shareholders' equity base. While equity remained relatively stable between 2022 and 2024, extraordinary earnings events created significant deviations in profitability metrics.
- Earnings-Driven Volatility
- A pronounced spike in ROE is observed starting in the fourth quarter of 2023, peaking at 54.95% by March 31, 2024. This surge correlates directly with a substantial increase in net earnings, which reached 26,028 million USD in October 2023. Such a sharp increase indicates the influence of non-recurring gains or one-time financial events that temporarily inflated the profitability ratio far beyond historical norms.
- Equity Base Evolution
- Total shareholders' equity exhibited a gradual expansion in the latter half of the analyzed period. From a low of 68,774 million USD in December 2023, the equity base grew steadily to 84,971 million USD by June 28, 2026. This increase in the equity base exerted a moderating effect on the ROE calculation during 2025 and 2026, contributing to a stabilization of the ratio as the denominator grew.
- Profitability Normalization
- Following the anomalous peak in early 2024, ROE reverted to a more sustainable range. A period of steady improvement is noted throughout 2025, where the ratio climbed from 27.92% in December 2024 to a peak of 32.87% in December 2025. However, a slight downward trend emerged in the first half of 2026, with the ratio settling at 24.76% by June 28, 2026, returning the company to performance levels similar to those seen in early 2022.
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Return on Assets (ROA)
| Jun 28, 2026 | Mar 29, 2026 | Dec 28, 2025 | Sep 28, 2025 | Jun 29, 2025 | Mar 30, 2025 | Dec 29, 2024 | Sep 29, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Oct 1, 2023 | Jul 2, 2023 | Apr 2, 2023 | Dec 31, 2022 | Oct 2, 2022 | Jul 3, 2022 | Apr 3, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in millions) | ||||||||||||||||||||||||
| Net earnings (loss) | 5,534) | 5,235) | 5,116) | 5,152) | 5,537) | 10,999) | 3,431) | 2,694) | 4,686) | 3,255) | 4,049) | 26,028) | 5,144) | (68) | 3,520) | 4,458) | 4,814) | 5,149) | ||||||
| Total assets | 201,061) | 200,894) | 199,210) | 192,816) | 193,389) | 193,671) | 180,104) | 178,287) | 181,088) | 171,966) | 167,558) | 166,061) | 191,686) | 195,969) | 187,378) | 175,124) | 177,724) | 178,355) | ||||||
| Profitability Ratio | ||||||||||||||||||||||||
| ROA1 | 10.46% | 10.47% | 13.46% | 13.03% | 11.72% | 11.26% | 7.81% | 8.24% | 20.99% | 22.37% | 20.98% | 20.85% | 6.81% | 6.49% | 9.57% | 10.94% | 10.33% | 11.12% | ||||||
| Benchmarks | ||||||||||||||||||||||||
| ROA, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 4.67% | 2.66% | 3.15% | 1.78% | 2.74% | 3.08% | 3.17% | 3.57% | 3.76% | 4.03% | 3.61% | 4.78% | 6.42% | 5.64% | 8.53% | 9.49% | 8.83% | 8.71% | ||||||
| Amgen Inc. | 9.14% | 8.43% | 8.51% | 7.77% | 7.53% | 6.64% | 4.45% | 4.65% | 3.44% | 4.05% | 6.91% | 8.36% | 8.84% | 8.92% | 10.06% | 10.73% | 11.09% | 9.67% | ||||||
| Bristol-Myers Squibb Co. | 10.59% | 8.41% | 7.83% | 6.23% | 5.33% | 5.86% | -9.66% | -7.75% | -6.91% | -6.21% | 8.43% | 9.08% | 8.52% | 7.75% | 6.53% | 6.80% | 6.59% | 6.07% | ||||||
| Danaher Corp. | 4.33% | 4.42% | 4.33% | 4.38% | 4.18% | 4.76% | 5.03% | 4.83% | 5.35% | 5.28% | 5.64% | 6.74% | 7.49% | 8.15% | 8.55% | 8.35% | 7.76% | 7.74% | ||||||
| Eli Lilly & Co. | 18.77% | 21.68% | 18.35% | 16.02% | 13.67% | 12.42% | 13.45% | 11.07% | 10.22% | 9.60% | 8.19% | 8.61% | 11.85% | 10.70% | 12.62% | 12.71% | 12.09% | 13.06% | ||||||
| Gilead Sciences Inc. | -6.56% | 16.38% | 14.42% | 13.86% | 11.33% | 10.57% | 0.81% | 0.23% | 1.97% | 0.86% | 9.12% | 9.42% | 8.80% | 9.02% | 7.27% | 5.33% | 6.58% | 7.16% | ||||||
| Merck & Co. Inc. | 2.44% | 6.94% | 13.34% | 14.69% | 13.96% | 15.14% | 14.62% | 10.34% | 12.20% | 2.18% | 0.34% | 4.32% | 2.98% | 12.09% | 13.30% | 14.25% | 15.48% | 13.29% | ||||||
| Pfizer Inc. | 2.15% | 3.61% | 3.73% | 4.71% | 5.22% | 3.79% | 3.76% | 1.94% | -1.20% | -0.14% | 0.94% | 4.87% | 9.75% | 14.85% | 15.91% | 15.32% | 15.01% | 13.58% | ||||||
| Regeneron Pharmaceuticals Inc. | 10.37% | 10.82% | 11.11% | 11.40% | 11.67% | 11.98% | 11.69% | 12.43% | 11.98% | 11.22% | 11.95% | 12.41% | 14.02% | 13.91% | 14.85% | 19.40% | 20.90% | 30.11% | ||||||
| Thermo Fisher Scientific Inc. | 6.16% | 6.05% | 6.08% | 6.38% | 6.50% | 6.58% | 6.51% | 6.11% | 6.32% | 6.21% | 6.07% | 6.12% | 6.08% | 6.36% | 7.15% | 7.77% | 8.21% | 8.20% | ||||||
| Vertex Pharmaceuticals Inc. | 16.06% | 16.38% | 15.42% | 14.78% | 15.13% | -4.32% | -2.38% | -2.16% | -2.43% | 16.81% | 15.92% | 15.97% | 16.54% | 17.18% | 18.30% | 19.59% | 20.50% | 17.19% | ||||||
Based on: 10-Q (reporting date: 2026-06-28), 10-Q (reporting date: 2026-03-29), 10-K (reporting date: 2025-12-28), 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-29), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03).
1 Q2 2026 Calculation
ROA = 100
× (Net earnings (loss)Q2 2026
+ Net earnings (loss)Q1 2026
+ Net earnings (loss)Q4 2025
+ Net earnings (loss)Q3 2025)
÷ Total assets
= 100 × (5,534 + 5,235 + 5,116 + 5,152)
÷ 201,061 = 10.46%
2 Click competitor name to see calculations.
The Return on Assets (ROA) exhibits significant volatility between April 2022 and June 2026, characterized by a period of extreme elevation in late 2023 and early 2024 followed by a return to a stabilized baseline. While the metric began the period within a range of 9.57% to 11.12%, it underwent a series of sharp fluctuations driven by substantial variances in net earnings and shifts in the total asset base.
- Net Earnings Volatility
- Net earnings remained relatively stable between 3.5 billion and 5.1 billion US$ for much of the period, with the exception of two major anomalies. A sharp contraction occurred in April 2023, with earnings falling to -68 million US$. This was followed by a massive surge in October 2023, where earnings peaked at 26.028 billion US$, and a secondary spike in March 2025 to 10.999 billion US$. These irregularities created significant deviations in the profitability ratios.
- Asset Base Dynamics
- The total asset base showed a general upward trajectory over the long term, growing from 178.355 billion US$ in April 2022 to 201.061 billion US$ by June 2026. However, a notable contraction is observed in late 2023, where assets dropped to a period low of 166.061 billion US$ in October 2023. This reduction in the asset base coincided with the peak in net earnings, contributing to an inflated ROA during that window.
- ROA Performance Cycles
- The ROA trend is divided into three distinct phases. First, a period of stability and slight decline occurred from April 2022 to July 2023, with values dipping to 6.49%. Second, an exceptional surge occurred between October 2023 and June 2024, with ROA peaking at 22.37% in March 2024, driven by the confluence of peak earnings and a minimized asset base. Third, a normalization phase is evident from late 2024 through June 2026, where the ratio recovered from a low of 7.81% to stabilize around 10.46%.
The data suggests that the exceptional profitability peaks observed in 2023 and early 2024 were likely the result of non-recurring financial events rather than sustainable operational growth. By the end of the analyzed period, the ROA returned to levels consistent with the 2022 baseline, despite a larger overall asset base, indicating a return to normalized operational efficiency.
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