Stock Analysis on Net
Stock Analysis on Net

Vertex Pharmaceuticals Inc. (NASDAQ:VRTX)

$24.99

Cash Flow Statement
Quarterly Data

The cash flow statement provides information about a company cash receipts and cash payments during an accounting period, showing how these cash flows link the ending cash balance to the beginning balance shown on the company balance sheet.

The cash flow statement consists of three parts: cash flows provided by (used in) operating activities, cash flows provided by (used in) investing activities, and cash flows provided by (used in) financing activities.

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Vertex Pharmaceuticals Inc., consolidated cash flow statement (quarterly data)

US$ in thousands

Microsoft Excel
3 months ended: Jun 30, 2026 Mar 31, 2026 Dec 31, 2025 Sep 30, 2025 Jun 30, 2025 Mar 31, 2025 Dec 31, 2024 Sep 30, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022 Dec 31, 2021 Sep 30, 2021 Jun 30, 2021 Mar 31, 2021
Net income (loss)
Stock-based compensation expense
Depreciation and amortization expense
Intangible asset impairment charge
Deferred income taxes
Other non-cash items, net
Accounts receivable
Inventories
Prepaid expenses and other assets
Accounts payable
Accrued expenses
Other liabilities
Changes in operating assets and liabilities
Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities
Net cash provided by (used in) operating activities
Purchases of available-for-sale debt securities
Sales and maturities of available-for-sale debt securities
Acquisition of available-for-sale debt securities from Alpine Immune Sciences, Inc.
Purchases of property and equipment
Proceeds related to convertible note
Net payments related to finite-lived intangible assets
Sale of equity securities
Payment to acquire business, net of cash acquired
Other investing activities
Net cash used in investing activities
Issuances of common stock under benefit plans
Repurchases of common stock
Payments in connection with common stock withheld for employee tax obligations
Payments on finance leases
Proceeds from finance leases
Other financing activities
Net cash used in financing activities
Effect of changes in exchange rates on cash
Net increase (decrease) in cash, cash equivalents and restricted cash

Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).


Operating cash flow demonstrates a pattern of consistent strength with a significant singular anomaly in the second quarter of 2024. For the majority of the analyzed period, net cash provided by operating activities typically ranges between 800 million and 1.4 billion US dollars per quarter, consistently exceeding net income due to the additive effects of stock-based compensation and depreciation. However, a substantial divergence occurred on June 30, 2024, where net income fell to negative 3.59 billion US dollars and operating cash flow dropped to negative 3.75 billion US dollars, indicating a massive non-recurring event or adjustment.

Operating Cash Flow Drivers
Stock-based compensation expense has trended upward, moving from approximately 115 million US dollars in early 2021 to a range of 160 million to 190 million US dollars by 2025 and 2026. Depreciation and amortization expenses also show a steady increase, rising from roughly 30 million US dollars per quarter in 2021 to over 55 million US dollars by mid-2026. These non-cash charges provide a consistent buffer that enhances cash flow relative to reported net income.
Investing Activity Patterns
The company maintains an active portfolio of available-for-sale debt securities, characterized by frequent and large-scale purchases and sales. Investment in property and equipment has accelerated over time; capital expenditures, which averaged between 40 million and 70 million US dollars per quarter from 2021 to 2023, increased significantly in 2025 and 2026, with several quarters exceeding 130 million US dollars.
Financing and Capital Allocation
Common stock repurchases represent the primary use of cash in financing activities. While buybacks were sporadic in 2021 and 2022, they became a sustained and aggressive strategy from 2023 onward, peaking in September 2025 with a repurchase of 1.07 billion US dollars. This trend indicates a shift toward returning substantial capital to shareholders.
Working Capital Volatility
Changes in operating assets and liabilities exhibit high quarterly volatility. Significant fluctuations are observed in accrued expenses and prepaid expenses, particularly in the later periods, which occasionally create large swings in the net cash provided by operations, such as the negative 947.8 million US dollar impact in December 2025.

Overall, the cash flow profile reveals a highly profitable core operation capable of generating significant liquidity. This liquidity is systematically deployed into increasing capital expenditures and an aggressive share repurchase program, despite the volatility introduced by investment portfolio management and a singular, extreme deficit in mid-2024.