Stock Analysis on Net

Vertex Pharmaceuticals Inc. (NASDAQ:VRTX)

$24.99

Financial Reporting Quality: Aggregate Accruals

Microsoft Excel

Earnings can be decomposed into cash and accrual components. The accrual component (aggregate accruals) has been found to have less persistence than the cash component, and therefore (1) earnings with higher accrual component are less persistent than earnings with smaller accrual component, all else equal; and (2) the cash component of earnings should receive a higher weighting evaluating company performance.

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Balance-Sheet-Based Accruals Ratio

Vertex Pharmaceuticals Inc., balance sheet computation of aggregate accruals

US$ in thousands

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Operating Assets
Total assets
Less: Cash and cash equivalents
Less: Marketable securities
Operating assets
Operating Liabilities
Total liabilities
Less: Current finance lease liabilities
Less: Long-term finance lease liabilities
Operating liabilities
 
Net operating assets1
Balance-sheet-based aggregate accruals2
Financial Ratio
Balance-sheet-based accruals ratio3
Benchmarks
Balance-Sheet-Based Accruals Ratio, Competitors4
AbbVie Inc.
Amgen Inc.
Bristol-Myers Squibb Co.
Danaher Corp.
Eli Lilly & Co.
Gilead Sciences Inc.
Johnson & Johnson
Merck & Co. Inc.
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Thermo Fisher Scientific Inc.
Balance-Sheet-Based Accruals Ratio, Sector
Pharmaceuticals, Biotechnology & Life Sciences
Balance-Sheet-Based Accruals Ratio, Industry
Health Care

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 2025 Calculation
Net operating assets = Operating assets – Operating liabilities
= =

2 2025 Calculation
Balance-sheet-based aggregate accruals = Net operating assets2025 – Net operating assets2024
= =

3 2025 Calculation
Balance-sheet-based accruals ratio = 100 × Balance-sheet-based aggregate accruals ÷ Avg. net operating assets
= 100 × ÷ [( + ) ÷ 2] =

4 Click competitor name to see calculations.


The balance-sheet-based accruals ratio exhibits significant fluctuations over the observed period. Net operating assets demonstrate a consistent upward trend, while aggregate accruals and the resulting accruals ratio display more volatile behavior.

Net Operating Assets
Net operating assets increased substantially from 3,605,800 in 2022 to 12,169,900 in 2025, indicating considerable growth in the company’s operational investments and activities. The growth rate appears to decelerate slightly between 2023 and 2025.
Balance-Sheet-Based Aggregate Accruals
Aggregate accruals rose dramatically from 474,000 in 2022 to 3,183,000 in 2023. They continued to increase, albeit at a slower pace, reaching 3,622,900 in 2024. A notable decrease is then observed in 2025, with aggregate accruals falling to 1,758,200. This suggests a changing pattern in the timing of cash flows relative to reported earnings.
Balance-Sheet-Based Accruals Ratio
The accruals ratio increased sharply from 14.07% in 2022 to 61.24% in 2023, representing a substantial reliance on accruals relative to net operating assets. The ratio decreased to 42.13% in 2024, indicating a partial reversion towards lower accrual levels. Finally, the ratio declined further to 15.57% in 2025, approaching the level observed in 2022. This pattern suggests potential shifts in accounting practices or operational cash flow generation. The high accruals ratio in 2023 warrants further investigation to assess the quality of earnings during that period.

The divergence between the growth in net operating assets and the fluctuations in aggregate accruals and the accruals ratio suggests a dynamic relationship between reported earnings and underlying cash flows. The significant increase and subsequent decrease in the accruals ratio should be examined in conjunction with other financial metrics and qualitative factors to determine the potential implications for financial reporting quality.


Cash-Flow-Statement-Based Accruals Ratio

Vertex Pharmaceuticals Inc., cash flow statement computation of aggregate accruals

US$ in thousands

Microsoft Excel
Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Net income (loss)
Less: Net cash provided by (used in) operating activities
Less: Net cash used in investing activities
Cash-flow-statement-based aggregate accruals
Financial Ratio
Cash-flow-statement-based accruals ratio1
Benchmarks
Cash-Flow-Statement-Based Accruals Ratio, Competitors2
AbbVie Inc.
Amgen Inc.
Bristol-Myers Squibb Co.
Danaher Corp.
Eli Lilly & Co.
Gilead Sciences Inc.
Johnson & Johnson
Merck & Co. Inc.
Pfizer Inc.
Regeneron Pharmaceuticals Inc.
Thermo Fisher Scientific Inc.
Cash-Flow-Statement-Based Accruals Ratio, Sector
Pharmaceuticals, Biotechnology & Life Sciences
Cash-Flow-Statement-Based Accruals Ratio, Industry
Health Care

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).

1 2025 Calculation
Cash-flow-statement-based accruals ratio = 100 × Cash-flow-statement-based aggregate accruals ÷ Avg. net operating assets
= 100 × ÷ [( + ) ÷ 2] =

2 Click competitor name to see calculations.


Net operating assets increased substantially over the four-year period, rising from US$3.6 billion in 2022 to US$12.2 billion in 2025. Concurrent with this growth, cash-flow-statement-based aggregate accruals exhibited significant fluctuations. The cash-flow-statement-based accruals ratio, which measures the relationship between accruals and operating assets, demonstrated a corresponding pattern of volatility.

Cash-Flow-Statement-Based Aggregate Accruals
In 2022, aggregate accruals were negative, totaling -US$486.8 million. This indicates that cash flows from operations exceeded reported net income. A substantial positive shift occurred in 2023, with accruals reaching US$3.2 billion. This suggests a significant difference between reported net income and actual cash generated from operations. Accruals remained positive in 2024, at US$3.7 billion, before decreasing to US$1.3 billion in 2025. The decline in 2025 suggests a narrowing gap between net income and cash flow.
Cash-Flow-Statement-Based Accruals Ratio
The accruals ratio was -14.45% in 2022, consistent with the negative accruals observed for that year. The ratio experienced a dramatic increase in 2023, reaching 62.03%. This substantial rise warrants further investigation, as it could indicate aggressive revenue recognition or delayed expense recognition. The ratio decreased to 43.34% in 2024, representing a continued, though lessened, divergence between earnings and cash flow. Finally, the ratio decreased significantly to 11.22% in 2025, suggesting a move towards greater alignment between reported earnings and cash flows. The overall trend indicates a decreasing reliance on accruals relative to operating assets as the period progresses.

The considerable fluctuations in both aggregate accruals and the accruals ratio suggest potential areas for further scrutiny. While growth in net operating assets is positive, the variability in accruals could signal changes in accounting practices or underlying business operations. The high accruals ratio in 2023 and 2024, in particular, may warrant a deeper dive into the components of accruals to assess the quality of earnings.