Stock Analysis on Net

Vertex Pharmaceuticals Inc. (NASDAQ:VRTX)

Statement of Comprehensive Income 

Vertex Pharmaceuticals Inc., consolidated statement of comprehensive income

US$ in thousands

Microsoft Excel
12 months ended: Dec 31, 2025 Dec 31, 2024 Dec 31, 2023 Dec 31, 2022 Dec 31, 2021
Net income (loss) 3,953,200 (535,600) 3,619,600 3,322,000 2,342,100
Unrealized holding gains (losses) on available-for-sale debt securities, net of tax 26,900 (2,500) 9,700 400 (800)
Unrealized gains (losses) on foreign currency forward contracts, net of tax (198,100) 136,000 (50,900) (4,100) 83,200
Foreign currency translation adjustment 27,500 8,600 26,100 (11,400) 2,000
Other comprehensive income (loss) (143,700) 142,100 (15,100) (15,100) 84,400
Comprehensive income (loss) 3,809,500 (393,500) 3,604,500 3,306,900 2,426,500

Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).


The statement of comprehensive income exhibits significant fluctuations over the five-year period. Net income demonstrates a generally positive trend, with substantial growth from 2021 to 2023, a significant loss in 2024, and a recovery in 2025. Other comprehensive income components contribute volatility to the overall comprehensive income.

Net Income
Net income increased from US$2,342.1 million in 2021 to US$3,322.0 million in 2022, and further to US$3,619.6 million in 2023. A substantial loss of US$535.6 million was recorded in 2024, followed by a strong recovery to US$3,953.2 million in 2025. This indicates considerable earnings variability.
Unrealized Holding Gains (Losses) on Available-for-Sale Debt Securities
This component shows relatively small gains and losses initially, with a gain of US$9.7 million in 2023. The gains increased substantially to US$26.9 million in 2025, after a loss of US$2.5 million in 2024. These fluctuations, while not dominating the overall picture, suggest active management or changing market conditions affecting debt security valuations.
Unrealized Gains (Losses) on Foreign Currency Forward Contracts
This item is characterized by significant volatility. A substantial gain of US$83.2 million was recorded in 2021, followed by a smaller loss in 2022. Larger losses were observed in 2023 and 2025 (US$50.9 million and US$198.1 million respectively), while a significant gain of US$136.0 million occurred in 2024. This suggests substantial exposure to, and active hedging of, foreign currency risk.
Foreign Currency Translation Adjustment
The foreign currency translation adjustment exhibits fluctuations, with a gain of US$2.0 million in 2021, a loss of US$11.4 million in 2022, a gain of US$26.1 million in 2023, a smaller gain of US$8.6 million in 2024, and a gain of US$27.5 million in 2025. These changes likely reflect the impact of exchange rate movements on the consolidation of foreign subsidiaries.
Other Comprehensive Income
Other comprehensive income mirrors the volatility of its components. A gain of US$84.4 million was recorded in 2021, followed by losses in 2022 and 2023 (US$15.1 million each). A substantial gain of US$142.1 million was observed in 2024, followed by a loss of US$143.7 million in 2025. This demonstrates the significant impact of non-net income items on overall comprehensive income.
Comprehensive Income
Comprehensive income generally follows the trend of net income, increasing from US$2,426.5 million in 2021 to US$3,604.5 million in 2023. The loss in net income in 2024 resulted in a comprehensive loss of US$393.5 million. Comprehensive income recovered to US$3,809.5 million in 2025, driven by the recovery in net income and positive contributions from other comprehensive income components.

Overall, the statement of comprehensive income reveals a business subject to considerable earnings variability, particularly influenced by fluctuations in foreign currency related items and, notably, a significant downturn in 2024 followed by a strong recovery in 2025. The impact of other comprehensive income components is substantial and contributes to the overall volatility.

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