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Vertex Pharmaceuticals Inc. (NASDAQ:VRTX)

Income Statement
Quarterly Data

Vertex Pharmaceuticals Inc., consolidated income statement (quarterly data)

US$ in thousands

Microsoft Excel
3 months ended: Sep 30, 2026 Jun 30, 2026 Mar 31, 2026 Dec 31, 2025 Sep 30, 2025 Jun 30, 2025 Mar 31, 2025 Dec 31, 2024 Sep 30, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022 Dec 31, 2021 Sep 30, 2021 Jun 30, 2021 Mar 31, 2021
Product revenues, net 3,440,800 3,333,900 2,986,900 3,190,000 3,076,400 2,944,000 2,760,200 2,912,000 2,771,900 2,645,600 2,690,600 2,517,700 2,483,500 2,493,200 2,374,800 2,302,700 2,334,300 2,196,200 2,097,500 2,072,561 1,984,164 1,793,370 1,723,305
Other revenues — — — — — 20,700 10,000 — — — — — — — — — — — — — — — 1,000
Revenues 3,440,800 3,333,900 2,986,900 3,190,000 3,076,400 2,964,700 2,770,200 2,912,000 2,771,900 2,645,600 2,690,600 2,517,700 2,483,500 2,493,200 2,374,800 2,302,700 2,334,300 2,196,200 2,097,500 2,072,561 1,984,164 1,793,370 1,724,305
Cost of sales (526,100) (489,200) (392,800) (466,000) (414,800) (407,500) (363,000) (423,400) (392,600) (371,900) (342,600) (368,000) (318,700) (308,600) (266,900) (283,300) (289,400) (261,800) (245,800) (247,387) (236,512) (227,972) (192,329)
Gross profit 2,914,700 2,844,700 2,594,100 2,724,000 2,661,600 2,557,200 2,407,200 2,488,600 2,379,300 2,273,700 2,348,000 2,149,700 2,164,800 2,184,600 2,107,900 2,019,400 2,044,900 1,934,400 1,851,700 1,825,174 1,747,652 1,565,398 1,531,976
Research and development expenses (1,320,600) (993,800) (961,600) (973,700) (977,700) (978,400) (979,700) (998,700) (875,900) (966,600) (789,100) (824,600) (810,000) (785,700) (742,600) (694,100) (645,000) (600,100) (601,100) (567,786) (467,051) (448,690) (454,273)
Acquired in-process research and development expenses (40,600) (21,400) (500) (56,500) (54,500) (2,200) (19,800) (87,500) (15,000) (4,449,100) (76,800) (17,800) (51,700) (110,500) (347,100) (22,600) (29,000) (61,900) (2,000) (126,500) (26,700) (958,400) (1,700)
Selling, general and administrative expenses (844,100) (582,200) (493,700) (487,000) (445,100) (424,600) (396,400) (377,600) (371,800) (372,200) (342,700) (369,100) (263,800) (262,600) (241,100) (267,400) (246,800) (215,300) (215,200) (255,165) (198,189) (194,669) (192,077)
Intangible asset impairment charge — — — — — — (379,000) — — — — — — — — — — — — — — — —
Change in fair value of contingent consideration 3,500 (400) (200) (900) 1,900 (900) (2,200) 1,200 (300) (500) 100 50,300 (1,200) 600 1,900 (1,800) 2,600 49,200 7,500 2,000 (1,200) (1,600) 3,900
Income (loss) from operations 712,900 1,246,900 1,138,100 1,205,900 1,186,200 1,151,100 630,100 1,026,000 1,116,300 (3,514,700) 1,139,500 988,500 1,038,100 1,026,400 779,000 1,033,500 1,126,700 1,106,300 1,040,900 877,723 1,054,512 (37,961) 887,826
Interest income 118,400 120,600 114,800 121,900 125,700 122,400 120,900 128,200 132,200 156,500 181,200 179,500 167,900 144,700 122,600 86,000 46,200 10,800 1,600 1,186 1,116 1,133 1,465
Interest expense (36,000) — — (3,300) (3,300) (3,700) (3,000) (2,800) (7,500) (9,900) (10,400) (10,600) (10,900) (11,200) (11,400) (11,600) (13,700) (14,600) (14,900) (15,089) (15,255) (15,478) (15,678)
Other income (expense), net (11,900) 24,300 — 6,500 (9,800) 13,200 (17,600) (14,900) (16,900) (23,100) (31,200) (9,800) (15,900) 1,600 1,300 (31,100) 17,200 (78,100) (72,800) 7,134 42,368 8,051 (52,653)
Income (loss) before (provision for) benefit from income taxes 783,400 1,391,800 1,252,900 1,331,000 1,298,800 1,283,000 730,400 1,136,500 1,224,100 (3,391,200) 1,279,100 1,147,600 1,179,200 1,161,500 891,500 1,076,800 1,176,400 1,024,400 954,800 870,954 1,082,741 (44,255) 820,960
(Provision for) benefit from income taxes (129,800) (292,000) (221,500) (139,900) (215,900) (250,100) (84,100) (223,500) (178,700) (202,400) (179,500) (178,800) (143,900) (245,800) (191,700) (257,900) (245,900) (213,900) (192,700) (100,844) (230,813) 111,179 (167,822)
Net income (loss) 653,600 1,099,800 1,031,400 1,191,100 1,082,900 1,032,900 646,300 913,000 1,045,400 (3,593,600) 1,099,600 968,800 1,035,300 915,700 699,800 818,900 930,500 810,500 762,100 770,110 851,928 66,924 653,138

Based on: 10-Q (reporting date: 2026-09-30), 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31).


The financial performance over the analyzed period is characterized by consistent top-line growth and high gross profitability, punctuated by significant non-recurring charges related to research and development acquisitions and asset impairments.

Revenue Trends and Gross Profitability
Total revenues exhibit a sustained upward trajectory, increasing from $1.72 billion in March 2021 to $3.44 billion by September 2026. This growth is almost entirely driven by net product revenues, which show a steady climb with only minor quarterly variances. Gross profit grew proportionally, rising from $1.53 billion to $2.91 billion over the same period. Despite the increase in the cost of sales, gross margins remained robust, indicating strong pricing power and efficient production of core products.
Operating Expense Analysis
Operating expenses have scaled significantly to support growth and pipeline expansion. Research and development (R&D) expenses grew from $454 million in March 2021 to $1.32 billion in September 2026, representing a strategic increase in investment in future product development. Similarly, selling, general, and administrative (SG&A) expenses saw a marked escalation, particularly from 2023 onwards, rising from $192 million in early 2021 to $844 million by the end of the period.
Non-Recurring Charges and Volatility
The income statement reflects significant volatility due to acquired in-process R&D expenses. A substantial one-time charge of $4.45 billion occurred in June 2024, which caused a sharp temporary decline in operating income and a resulting net loss for that quarter. Additionally, an intangible asset impairment charge of $379 million was recorded in March 2025. These events highlight a strategy of aggressive inorganic growth through acquisitions, which introduces periodic volatility into the net income.
Operating and Net Income Performance
Excluding the anomalous June 2024 charge, income from operations remained generally stable and positive, typically fluctuating between $700 million and $1.25 billion per quarter. Net income followed a similar pattern, generally trending upward from $653 million in March 2021 to $653 million in September 2026, though peaking at $1.19 billion in December 2025. The company's ability to maintain profitability despite rising R&D and SG&A costs suggests a high-margin core business model.
Financial Income and Tax Impact
Interest income showed a notable increase, rising from $1.47 million in early 2021 to peak around $181 million in early 2024, suggesting a significant accumulation of cash and cash equivalents. Conversely, interest expenses trended downward over most of the period, improving the overall non-operating margin. Provision for income taxes remained a consistent drag on the bottom line, typically ranging between $130 million and $292 million per quarter.

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