Analysis of Solvency Ratios
Quarterly Data
Solvency ratios also known as long-term debt ratios measure a company ability to meet long-term obligations.
Solvency Ratios (Summary)
Vertex Pharmaceuticals Inc., solvency ratios (quarterly data)
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
The company maintains an exceptionally strong solvency profile characterized by minimal reliance on debt and a high capacity to service financial obligations. Throughout the analyzed period, solvency ratios remained conservative, with a marginal increase in leverage beginning in the second quarter of 2024.
- Debt Utilization Ratios
- Debt to equity, debt to capital, and debt to assets ratios remained remarkably low and stable between March 2022 and March 2024, generally fluctuating between 0.02 and 0.03. Starting in June 2024, a moderate upward shift occurred, with debt to equity and debt to capital ratios peaking around 0.10 to 0.11 and debt to assets reaching 0.08 by March 2026. Despite this increase, the overall levels of indebtedness relative to equity, capital, and assets remain negligible, indicating a highly equity-funded capital structure.
- Financial Leverage
- Financial leverage exhibited stability for the first two years of the period, hovering around 1.30. A slight elevation is observed from June 2024 onwards, with the ratio peaking at 1.44 in September 2025 before stabilizing at 1.37. This suggests a slight increase in the use of liabilities to finance assets, though the impact on the overall risk profile is minimal.
- Interest Coverage and Debt Servicing
- The interest coverage ratio demonstrated significant volatility and extreme growth. From March 2022 to March 2024, the ratio grew steadily from 48.17 to 111.61, indicating a rapidly increasing ability to cover interest expenses. A sharp contraction occurred in June 2024, dropping to 6.14, with a subsequent dip into negative territory (-11.94) in March 2025, suggesting a period of temporary earnings volatility or significant non-recurring expenses. However, a dramatic recovery followed, with the ratio surging to 502.52 by March 2026, reflecting an overwhelming capacity to meet interest obligations from operating profits.
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Debt Ratios
Coverage Ratios
Debt to Equity
Vertex Pharmaceuticals Inc., debt to equity calculation (quarterly data)
| Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | |||||||||||||||||||||||
| Total debt | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | ||||||
| Shareholders’ equity | 19,361,900) | 18,665,800) | 17,318,800) | 17,175,400) | 16,496,300) | 16,409,600) | 15,630,900) | 14,774,700) | 18,546,600) | 17,580,400) | 16,512,800) | 15,470,200) | 14,432,300) | 13,912,700) | 13,029,600) | 11,933,500) | 10,907,000) | ||||||
| Solvency Ratio | |||||||||||||||||||||||
| Debt to equity1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||||
| Benchmarks | |||||||||||||||||||||||
| Debt to Equity, Competitors2 | |||||||||||||||||||||||
| AbbVie Inc. | — | — | — | — | 49.22 | 20.19 | 11.78 | 10.42 | 9.24 | 5.73 | 5.02 | 4.74 | 4.68 | 3.67 | 4.35 | 4.98 | 4.51 | ||||||
| Amgen Inc. | 6.24 | 6.31 | 5.67 | 7.57 | 9.24 | 10.23 | 8.02 | 10.57 | 12.75 | 10.37 | 7.90 | 9.08 | 11.52 | 10.64 | 10.60 | 15.10 | 40.23 | ||||||
| Bristol-Myers Squibb Co. | 2.22 | 2.44 | 2.64 | 2.82 | 2.86 | 3.04 | 2.90 | 3.08 | 3.38 | 1.35 | 1.30 | 1.18 | 1.19 | 1.27 | 1.20 | 1.29 | 1.42 | ||||||
| Danaher Corp. | 0.35 | 0.35 | 0.33 | 0.33 | 0.32 | 0.32 | 0.34 | 0.34 | 0.34 | 0.34 | 0.42 | 0.38 | 0.39 | 0.39 | 0.41 | 0.43 | 0.47 | ||||||
| Eli Lilly & Co. | 1.39 | 1.60 | 1.79 | 2.18 | 2.44 | 2.37 | 2.19 | 2.13 | 2.05 | 2.34 | 1.80 | 1.70 | 1.69 | 1.52 | 1.58 | 1.97 | 1.77 | ||||||
| Gilead Sciences Inc. | 0.94 | 1.10 | 1.16 | 1.27 | 1.30 | 1.38 | 1.26 | 1.28 | 1.44 | 1.09 | 1.12 | 1.19 | 1.20 | 1.19 | 1.20 | 1.30 | 1.32 | ||||||
| Johnson & Johnson | 0.68 | 0.59 | 0.58 | 0.65 | 0.67 | 0.51 | 0.51 | 0.58 | 0.48 | 0.43 | 0.42 | 0.61 | 0.75 | 0.52 | 0.43 | 0.43 | 0.44 | ||||||
| Merck & Co. Inc. | 1.07 | 0.94 | 0.80 | 0.72 | 0.72 | 0.80 | 0.86 | 0.87 | 0.85 | 0.93 | 0.85 | 0.95 | 0.66 | 0.67 | 0.68 | 0.73 | 0.78 | ||||||
| Pfizer Inc. | 0.72 | 0.75 | 0.66 | 0.70 | 0.69 | 0.73 | 0.73 | 0.79 | 0.75 | 0.81 | 0.66 | 0.66 | 0.36 | 0.37 | 0.40 | 0.46 | 0.44 | ||||||
| Regeneron Pharmaceuticals Inc. | 0.09 | 0.09 | 0.09 | 0.09 | 0.09 | 0.09 | 0.09 | 0.10 | 0.10 | 0.10 | 0.11 | 0.11 | 0.11 | 0.12 | 0.13 | 0.13 | 0.14 | ||||||
| Thermo Fisher Scientific Inc. | 0.83 | 0.74 | 0.70 | 0.70 | 0.69 | 0.63 | 0.72 | 0.75 | 0.78 | 0.75 | 0.78 | 0.78 | 0.83 | 0.78 | 0.67 | 0.72 | 0.81 | ||||||
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q1 2026 Calculation
Debt to equity = Total debt ÷ Shareholders’ equity
= 0 ÷ 19,361,900 = 0.00
2 Click competitor name to see calculations.
The available financial data indicates a capital structure characterized by the absence of reported total debt throughout the period from March 31, 2022, to March 31, 2026. This results in a debt-to-equity ratio that remains unrecorded, suggesting a solvency profile that relies entirely on equity financing.
- Debt to Equity Ratio
- Due to the absence of total debt figures across all eighteen quarters, the debt-to-equity ratio cannot be calculated. The lack of debt obligations indicates a high degree of solvency and a minimal reliance on external borrowed funds to finance operations and growth.
- Shareholders' Equity Trends
- Shareholders' equity demonstrates a general long-term upward trajectory, rising from 10,907,000 thousand US dollars in March 2022 to 19,361,900 thousand US dollars by March 2026. This represents a substantial increase in the net book value of the company over the analyzed timeframe.
- Equity Volatility
- A significant contraction in shareholders' equity is observed between March 31, 2024, and June 30, 2024, where the value decreased from 18,546,600 thousand US dollars to 14,774,700 thousand US dollars. Following this decline, a consistent recovery phase is evident, with equity levels steadily climbing through the remainder of the period to reach a peak in March 2026.
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Debt to Equity (including Operating Lease Liability)
Vertex Pharmaceuticals Inc., debt to equity (including operating lease liability) calculation (quarterly data)
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q1 2026 Calculation
Debt to equity (including operating lease liability) = Total debt (including operating lease liability) ÷ Shareholders’ equity
= 1,986,500 ÷ 19,361,900 = 0.10
The solvency profile exhibits a transition from a state of minimal debt reliance to a more leveraged position, although the company maintains a substantial equity cushion throughout the analyzed period.
- Total Debt Evolution
- Debt levels remained relatively stagnant between March 2022 and March 2024, fluctuating within a narrow range of approximately 348 million to 382 million. A significant escalation occurred in mid-2024, with total debt rising to 586.8 million in June and spiking to 1.588 billion by September 2024. This upward trajectory continued more gradually thereafter, reaching 1.986 billion by March 2026.
- Shareholders' Equity Dynamics
- Equity demonstrated a consistent growth pattern from March 2022, rising from 10.9 billion to a peak of 18.5 billion in March 2024. A sharp contraction is observed in June 2024, where equity decreased to 14.77 billion. Following this decline, a steady recovery phase ensued, with equity climbing back to 19.36 billion by the conclusion of the period.
- Debt to Equity Ratio Analysis
- The debt-to-equity ratio remained negligible, ranging between 0.02 and 0.03, from March 2022 through March 2024. The simultaneous increase in debt and decrease in equity during mid-2024 caused the ratio to climb to 0.10 by September 2024. For the remainder of the analyzed timeframe, the ratio stabilized between 0.09 and 0.11, indicating that despite the increase in borrowed capital, the company maintains a highly conservative solvency position with low financial leverage.
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Debt to Capital
Vertex Pharmaceuticals Inc., debt to capital calculation (quarterly data)
| Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | |||||||||||||||||||||||
| Total debt | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | ||||||
| Shareholders’ equity | 19,361,900) | 18,665,800) | 17,318,800) | 17,175,400) | 16,496,300) | 16,409,600) | 15,630,900) | 14,774,700) | 18,546,600) | 17,580,400) | 16,512,800) | 15,470,200) | 14,432,300) | 13,912,700) | 13,029,600) | 11,933,500) | 10,907,000) | ||||||
| Total capital | 19,361,900) | 18,665,800) | 17,318,800) | 17,175,400) | 16,496,300) | 16,409,600) | 15,630,900) | 14,774,700) | 18,546,600) | 17,580,400) | 16,512,800) | 15,470,200) | 14,432,300) | 13,912,700) | 13,029,600) | 11,933,500) | 10,907,000) | ||||||
| Solvency Ratio | |||||||||||||||||||||||
| Debt to capital1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||||
| Benchmarks | |||||||||||||||||||||||
| Debt to Capital, Competitors2 | |||||||||||||||||||||||
| AbbVie Inc. | 1.10 | 1.05 | 1.04 | 1.00 | 0.98 | 0.95 | 0.92 | 0.91 | 0.90 | 0.85 | 0.83 | 0.83 | 0.82 | 0.79 | 0.81 | 0.83 | 0.82 | ||||||
| Amgen Inc. | 0.86 | 0.86 | 0.85 | 0.88 | 0.90 | 0.91 | 0.89 | 0.91 | 0.93 | 0.91 | 0.89 | 0.90 | 0.92 | 0.91 | 0.91 | 0.94 | 0.98 | ||||||
| Bristol-Myers Squibb Co. | 0.69 | 0.71 | 0.73 | 0.74 | 0.74 | 0.75 | 0.74 | 0.75 | 0.77 | 0.57 | 0.56 | 0.54 | 0.54 | 0.56 | 0.54 | 0.56 | 0.59 | ||||||
| Danaher Corp. | 0.26 | 0.26 | 0.25 | 0.25 | 0.24 | 0.24 | 0.25 | 0.25 | 0.25 | 0.26 | 0.30 | 0.28 | 0.28 | 0.28 | 0.29 | 0.30 | 0.32 | ||||||
| Eli Lilly & Co. | 0.58 | 0.62 | 0.64 | 0.69 | 0.71 | 0.70 | 0.69 | 0.68 | 0.67 | 0.70 | 0.64 | 0.63 | 0.63 | 0.60 | 0.61 | 0.66 | 0.64 | ||||||
| Gilead Sciences Inc. | 0.49 | 0.52 | 0.54 | 0.56 | 0.57 | 0.58 | 0.56 | 0.56 | 0.59 | 0.52 | 0.53 | 0.54 | 0.55 | 0.54 | 0.54 | 0.56 | 0.57 | ||||||
| Johnson & Johnson | 0.40 | 0.37 | 0.37 | 0.39 | 0.40 | 0.34 | 0.34 | 0.37 | 0.32 | 0.30 | 0.30 | 0.38 | 0.43 | 0.34 | 0.30 | 0.30 | 0.31 | ||||||
| Merck & Co. Inc. | 0.52 | 0.48 | 0.44 | 0.42 | 0.42 | 0.44 | 0.46 | 0.46 | 0.46 | 0.48 | 0.46 | 0.49 | 0.40 | 0.40 | 0.41 | 0.42 | 0.44 | ||||||
| Pfizer Inc. | 0.42 | 0.43 | 0.40 | 0.41 | 0.41 | 0.42 | 0.42 | 0.44 | 0.43 | 0.45 | 0.40 | 0.40 | 0.26 | 0.27 | 0.28 | 0.32 | 0.31 | ||||||
| Regeneron Pharmaceuticals Inc. | 0.08 | 0.08 | 0.08 | 0.08 | 0.08 | 0.08 | 0.08 | 0.09 | 0.09 | 0.09 | 0.10 | 0.10 | 0.10 | 0.11 | 0.11 | 0.12 | 0.12 | ||||||
| Thermo Fisher Scientific Inc. | 0.45 | 0.42 | 0.41 | 0.41 | 0.41 | 0.39 | 0.42 | 0.43 | 0.44 | 0.43 | 0.44 | 0.44 | 0.45 | 0.44 | 0.40 | 0.42 | 0.45 | ||||||
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q1 2026 Calculation
Debt to capital = Total debt ÷ Total capital
= 0 ÷ 19,361,900 = 0.00
2 Click competitor name to see calculations.
The financial structure is characterized by a complete absence of reported total debt from March 31, 2022, through March 31, 2026. This indicates a capital base funded entirely without the use of interest-bearing debt instruments during the analyzed timeframe.
- Debt to Capital Ratio
- The debt to capital ratio remains constant at zero throughout the entire period. This reflects a highly conservative solvency position with no leverage, effectively eliminating the risk of debt-related insolvency.
- Total Capital Evolution
- A consistent upward trajectory in total capital is observed from March 31, 2022, at 10.9 billion, peaking at 18.5 billion by March 31, 2024. A notable contraction occurred on June 30, 2024, where total capital decreased to 14.7 billion. Following this decline, a steady recovery trend is evident, with total capital increasing quarterly to reach 19.3 billion by March 31, 2026.
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Debt to Capital (including Operating Lease Liability)
Vertex Pharmaceuticals Inc., debt to capital (including operating lease liability) calculation (quarterly data)
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q1 2026 Calculation
Debt to capital (including operating lease liability) = Total debt (including operating lease liability) ÷ Total capital (including operating lease liability)
= 1,986,500 ÷ 21,348,400 = 0.09
The solvency profile reflects a transition from an extremely conservative capital structure to one with moderately increased leverage starting in mid-2024. While total debt remained relatively static for the first several quarters, a significant expansion in borrowing occurred in the latter half of the analyzed period, though the company maintains a strong overall solvency position with a low debt-to-capital ratio.
- Debt Accumulation Trends
- Between March 2022 and March 2024, total debt, including operating lease liabilities, remained stable, fluctuating within a narrow range between 348.6 million and 382.3 million. A sharp upward trajectory began in June 2024, where debt increased to 586.8 million, followed by a substantial spike to 1.58 billion by September 2024. This growth trend continued through March 2026, with total debt reaching a peak of 1.98 billion.
- Total Capital Dynamics
- Total capital exhibited a consistent upward trend from March 2022, rising from 11.28 billion to 18.91 billion by March 2024. A notable contraction occurred in June 2024, where capital decreased to 15.36 billion, before resuming a steady climb to 21.35 billion by March 2026. This suggests that while the capital base has grown significantly over the long term, there was a period of volatility coinciding with the initial increase in debt levels.
- Debt to Capital Ratio Analysis
- The debt to capital ratio remained nearly flat at 0.02 to 0.03 from March 2022 through March 2024, indicating a negligible reliance on borrowed funds relative to the total capital base. Following the debt expansion in mid-2024, the ratio rose to 0.09 by September 2024. For the remainder of the period, the ratio stabilized between 0.08 and 0.10. Despite the five-fold increase in total debt, the ratio remains low, suggesting that the company's capital growth has largely kept pace with its increased borrowing.
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Debt to Assets
Vertex Pharmaceuticals Inc., debt to assets calculation (quarterly data)
| Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | |||||||||||||||||||||||
| Total debt | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | ||||||
| Total assets | 26,484,400) | 25,643,000) | 24,862,300) | 24,036,700) | 22,880,500) | 22,533,200) | 22,240,200) | 20,132,100) | 23,917,400) | 22,730,200) | 21,726,200) | 20,349,200) | 18,974,200) | 18,150,900) | 16,706,400) | 15,582,200) | 14,256,100) | ||||||
| Solvency Ratio | |||||||||||||||||||||||
| Debt to assets1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||||
| Benchmarks | |||||||||||||||||||||||
| Debt to Assets, Competitors2 | |||||||||||||||||||||||
| AbbVie Inc. | 0.53 | 0.50 | 0.51 | 0.51 | 0.51 | 0.50 | 0.50 | 0.50 | 0.50 | 0.44 | 0.45 | 0.45 | 0.46 | 0.46 | 0.49 | 0.51 | 0.51 | ||||||
| Amgen Inc. | 0.62 | 0.60 | 0.61 | 0.64 | 0.64 | 0.65 | 0.66 | 0.69 | 0.69 | 0.67 | 0.67 | 0.68 | 0.69 | 0.60 | 0.61 | 0.62 | 0.62 | ||||||
| Bristol-Myers Squibb Co. | 0.51 | 0.50 | 0.51 | 0.52 | 0.54 | 0.54 | 0.53 | 0.55 | 0.56 | 0.42 | 0.41 | 0.40 | 0.40 | 0.41 | 0.40 | 0.42 | 0.44 | ||||||
| Danaher Corp. | 0.22 | 0.22 | 0.21 | 0.21 | 0.21 | 0.21 | 0.22 | 0.22 | 0.22 | 0.22 | 0.25 | 0.23 | 0.23 | 0.23 | 0.24 | 0.25 | 0.26 | ||||||
| Eli Lilly & Co. | 0.37 | 0.38 | 0.37 | 0.40 | 0.43 | 0.43 | 0.41 | 0.40 | 0.41 | 0.39 | 0.35 | 0.34 | 0.36 | 0.33 | 0.33 | 0.36 | 0.35 | ||||||
| Gilead Sciences Inc. | 0.39 | 0.42 | 0.43 | 0.45 | 0.44 | 0.45 | 0.43 | 0.44 | 0.45 | 0.40 | 0.40 | 0.40 | 0.41 | 0.40 | 0.40 | 0.42 | 0.42 | ||||||
| Johnson & Johnson | 0.27 | 0.24 | 0.24 | 0.26 | 0.27 | 0.20 | 0.20 | 0.23 | 0.20 | 0.18 | 0.18 | 0.24 | 0.27 | 0.21 | 0.18 | 0.18 | 0.19 | ||||||
| Merck & Co. Inc. | 0.38 | 0.36 | 0.32 | 0.30 | 0.30 | 0.32 | 0.32 | 0.34 | 0.32 | 0.33 | 0.33 | 0.35 | 0.29 | 0.28 | 0.28 | 0.30 | 0.30 | ||||||
| Pfizer Inc. | 0.31 | 0.31 | 0.30 | 0.30 | 0.30 | 0.30 | 0.31 | 0.32 | 0.31 | 0.32 | 0.30 | 0.30 | 0.18 | 0.18 | 0.19 | 0.21 | 0.20 | ||||||
| Regeneron Pharmaceuticals Inc. | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.08 | 0.08 | 0.08 | 0.09 | 0.09 | 0.09 | 0.10 | 0.10 | 0.10 | ||||||
| Thermo Fisher Scientific Inc. | 0.38 | 0.36 | 0.35 | 0.35 | 0.35 | 0.32 | 0.35 | 0.36 | 0.37 | 0.35 | 0.36 | 0.36 | 0.37 | 0.35 | 0.32 | 0.33 | 0.36 | ||||||
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q1 2026 Calculation
Debt to assets = Total debt ÷ Total assets
= 0 ÷ 26,484,400 = 0.00
2 Click competitor name to see calculations.
The financial data indicates a sustained long-term expansion of the total asset base, despite a temporary volatility period observed in 2024.
- Total Asset Trends
- Total assets exhibited consistent growth from March 31, 2022, starting at 14.26 billion US$ and climbing to 23.92 billion US$ by March 31, 2024. A significant contraction occurred on June 30, 2024, with assets decreasing to 20.13 billion US$. Following this dip, a recovery trend was established, with assets steadily increasing over the subsequent quarters to reach 26.48 billion US$ by March 31, 2026.
- Debt to Assets Analysis
- A determination of the debt to assets ratio is not possible due to the absence of total debt figures across all reporting periods. Consequently, the solvency position and the proportion of assets financed through debt cannot be quantified from the available information.
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Debt to Assets (including Operating Lease Liability)
Vertex Pharmaceuticals Inc., debt to assets (including operating lease liability) calculation (quarterly data)
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q1 2026 Calculation
Debt to assets (including operating lease liability) = Total debt (including operating lease liability) ÷ Total assets
= 1,986,500 ÷ 26,484,400 = 0.08
The solvency profile of the organization exhibits a distinct shift in leverage strategy beginning in mid-2024. For the initial period spanning March 2022 to March 2024, the company maintained a highly conservative capital structure characterized by minimal debt relative to its asset base.
- Total Debt Trends
- Between March 2022 and March 2024, total debt, including operating lease liabilities, remained stable, fluctuating within a narrow range between 348.6 million and 382.3 million USD. A significant escalation occurred in June 2024, with debt rising to 586.8 million USD, followed by a substantial surge to 1.588 billion USD by September 2024. Following this spike, debt levels remained elevated and trended gradually upward to reach 1.986 billion USD by March 2026.
- Total Asset Growth
- Total assets demonstrated a consistent upward trajectory from 14.256 billion USD in March 2022 to 23.917 billion USD in March 2024. A temporary contraction was observed in June 2024, where assets decreased to 20.132 billion USD, before resuming a steady growth pattern to conclude at 26.484 billion USD in March 2026.
- Debt to Assets Ratio Analysis
- The debt to assets ratio remained exceptionally low, fluctuating between 0.02 and 0.03 throughout the 2022 and 2023 periods. In alignment with the increased borrowing in the second half of 2024, the ratio climbed to 0.07 by September 2024. Although a slight decrease to 0.06 was noted in June 2025, the ratio trended upward to finish at 0.08 by March 2026. This shift represents a quantitative increase in leverage, yet the overall ratio indicates that the organization continues to maintain a strong solvency position with a primary reliance on equity for asset financing.
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Financial Leverage
Vertex Pharmaceuticals Inc., financial leverage calculation (quarterly data)
| Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | |||||||||||||||||||||||
| Total assets | 26,484,400) | 25,643,000) | 24,862,300) | 24,036,700) | 22,880,500) | 22,533,200) | 22,240,200) | 20,132,100) | 23,917,400) | 22,730,200) | 21,726,200) | 20,349,200) | 18,974,200) | 18,150,900) | 16,706,400) | 15,582,200) | 14,256,100) | ||||||
| Shareholders’ equity | 19,361,900) | 18,665,800) | 17,318,800) | 17,175,400) | 16,496,300) | 16,409,600) | 15,630,900) | 14,774,700) | 18,546,600) | 17,580,400) | 16,512,800) | 15,470,200) | 14,432,300) | 13,912,700) | 13,029,600) | 11,933,500) | 10,907,000) | ||||||
| Solvency Ratio | |||||||||||||||||||||||
| Financial leverage1 | 1.37 | 1.37 | 1.44 | 1.40 | 1.39 | 1.37 | 1.42 | 1.36 | 1.29 | 1.29 | 1.32 | 1.32 | 1.31 | 1.30 | 1.28 | 1.31 | 1.31 | ||||||
| Benchmarks | |||||||||||||||||||||||
| Financial Leverage, Competitors2 | |||||||||||||||||||||||
| AbbVie Inc. | — | — | — | — | 95.89 | 40.65 | 23.78 | 20.94 | 18.59 | 13.00 | 11.26 | 10.52 | 10.14 | 8.04 | 8.84 | 9.77 | 8.80 | ||||||
| Amgen Inc. | 10.07 | 10.46 | 9.37 | 11.83 | 14.40 | 15.63 | 12.07 | 15.34 | 18.51 | 15.59 | 11.83 | 13.31 | 16.59 | 17.79 | 17.44 | 24.51 | 64.62 | ||||||
| Bristol-Myers Squibb Co. | 4.31 | 4.87 | 5.22 | 5.43 | 5.32 | 5.67 | 5.46 | 5.56 | 6.01 | 3.23 | 3.15 | 2.92 | 2.96 | 3.12 | 3.01 | 3.08 | 3.26 | ||||||
| Danaher Corp. | 1.58 | 1.59 | 1.56 | 1.56 | 1.56 | 1.57 | 1.57 | 1.57 | 1.56 | 1.58 | 1.67 | 1.64 | 1.65 | 1.68 | 1.72 | 1.76 | 1.80 | ||||||
| Eli Lilly & Co. | 3.74 | 4.24 | 4.83 | 5.52 | 5.67 | 5.55 | 5.31 | 5.30 | 4.99 | 5.94 | 5.16 | 4.95 | 4.75 | 4.65 | 4.71 | 5.51 | 5.03 | ||||||
| Gilead Sciences Inc. | 2.39 | 2.60 | 2.72 | 2.83 | 2.95 | 3.05 | 2.95 | 2.93 | 3.21 | 2.72 | 2.80 | 2.95 | 2.95 | 2.97 | 2.97 | 3.11 | 3.17 | ||||||
| Johnson & Johnson | 2.47 | 2.44 | 2.43 | 2.46 | 2.48 | 2.52 | 2.54 | 2.53 | 2.46 | 2.44 | 2.33 | 2.55 | 2.77 | 2.44 | 2.35 | 2.33 | 2.39 | ||||||
| Merck & Co. Inc. | 2.80 | 2.60 | 2.50 | 2.40 | 2.38 | 2.53 | 2.64 | 2.58 | 2.62 | 2.84 | 2.59 | 2.70 | 2.30 | 2.37 | 2.41 | 2.48 | 2.61 | ||||||
| Pfizer Inc. | 2.30 | 2.41 | 2.25 | 2.32 | 2.30 | 2.42 | 2.38 | 2.47 | 2.40 | 2.54 | 2.22 | 2.22 | 1.94 | 2.06 | 2.10 | 2.24 | 2.23 | ||||||
| Regeneron Pharmaceuticals Inc. | 1.30 | 1.30 | 1.30 | 1.28 | 1.28 | 1.29 | 1.28 | 1.28 | 1.27 | 1.27 | 1.29 | 1.28 | 1.28 | 1.29 | 1.29 | 1.32 | 1.32 | ||||||
| Thermo Fisher Scientific Inc. | 2.18 | 2.07 | 2.02 | 2.00 | 2.01 | 1.96 | 2.05 | 2.08 | 2.13 | 2.11 | 2.14 | 2.15 | 2.24 | 2.21 | 2.08 | 2.14 | 2.26 | ||||||
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q1 2026 Calculation
Financial leverage = Total assets ÷ Shareholders’ equity
= 26,484,400 ÷ 19,361,900 = 1.37
2 Click competitor name to see calculations.
The financial position exhibits a sustained expansion of the balance sheet from March 2022 through March 2026, characterized by a consistent upward trajectory in both total assets and shareholders' equity, interrupted only by a temporary contraction in mid-2024.
- Asset and Equity Growth Trends
- Total assets increased from 14.26 billion USD in March 2022 to 26.48 billion USD by March 2026. This growth was closely mirrored by shareholders' equity, which expanded from 10.91 billion USD to 19.36 billion USD. A significant outlier is observed in June 2024, where total assets declined to 20.13 billion USD and shareholders' equity dropped to 14.77 billion USD, representing a sharp but temporary reduction in the balance sheet size before growth resumed.
- Financial Leverage Analysis
- Between March 2022 and March 2024, the financial leverage ratio remained highly stable, fluctuating within a narrow range of 1.28 to 1.32. This indicates a disciplined and consistent approach to the company's capital structure during this period.
- Capital Structure Shifts
- A period of increased leverage is evident starting in June 2024, with the ratio rising to 1.36 and peaking at 1.44 in September 2025. This upward trend indicates a higher proportion of debt or liabilities relative to equity during this interval. Following this peak, the leverage ratio corrected to 1.37 by December 2025 and remained constant through March 2026, suggesting a stabilization of the financial leverage at a slightly higher level than the 2022-2024 baseline.
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Interest Coverage
Vertex Pharmaceuticals Inc., interest coverage calculation (quarterly data)
| Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | |||||||||||||||||||||||
| Net income (loss) | 1,031,400) | 1,191,100) | 1,082,900) | 1,032,900) | 646,300) | 913,000) | 1,045,400) | (3,593,600) | 1,099,600) | 968,800) | 1,035,300) | 915,700) | 699,800) | 818,900) | 930,500) | 810,500) | 762,100) | ||||||
| Add: Income tax expense | 221,500) | 139,900) | 215,900) | 250,100) | 84,100) | 223,500) | 178,700) | 202,400) | 179,500) | 178,800) | 143,900) | 245,800) | 191,700) | 257,900) | 245,900) | 213,900) | 192,700) | ||||||
| Add: Interest expense | —) | 3,300) | 3,300) | 3,700) | 3,000) | 2,800) | 7,500) | 9,900) | 10,400) | 10,600) | 10,900) | 11,200) | 11,400) | 11,600) | 13,700) | 14,600) | 14,900) | ||||||
| Earnings before interest and tax (EBIT) | 1,252,900) | 1,334,300) | 1,302,100) | 1,286,700) | 733,400) | 1,139,300) | 1,231,600) | (3,381,300) | 1,289,500) | 1,158,200) | 1,190,100) | 1,172,700) | 902,900) | 1,088,400) | 1,190,100) | 1,039,000) | 969,700) | ||||||
| Solvency Ratio | |||||||||||||||||||||||
| Interest coverage1 | 502.52 | 350.11 | 348.55 | 258.29 | -11.94 | 9.12 | 7.76 | 6.14 | 111.61 | 100.32 | 96.54 | 90.90 | 82.27 | 78.23 | 70.08 | 66.72 | 48.17 | ||||||
| Benchmarks | |||||||||||||||||||||||
| Interest Coverage, Competitors2 | |||||||||||||||||||||||
| Amgen Inc. | 4.38 | 4.26 | 3.89 | 3.53 | 3.18 | 2.46 | 2.45 | 2.10 | 2.38 | 3.73 | 4.54 | 5.43 | 6.51 | 6.22 | 6.83 | 6.97 | 6.40 | ||||||
| Danaher Corp. | 17.95 | 16.97 | 16.41 | 15.01 | 16.80 | 17.71 | 16.11 | 17.61 | 17.81 | 18.64 | 23.66 | 29.65 | 35.60 | 40.30 | 41.32 | 35.26 | 33.54 | ||||||
| Gilead Sciences Inc. | 11.68 | 10.57 | 10.71 | 8.20 | 7.94 | 1.71 | 1.18 | 2.58 | 2.11 | 8.27 | 8.88 | 9.03 | 8.84 | 7.22 | 5.80 | 6.73 | 6.97 | ||||||
| Johnson & Johnson | 25.00 | 34.55 | 36.24 | 33.48 | 34.09 | 23.10 | 23.92 | 26.40 | 29.06 | 20.51 | 19.09 | 23.89 | 31.49 | 79.71 | 141.63 | 160.27 | 164.15 | ||||||
| Regeneron Pharmaceuticals Inc. | 108.44 | 120.42 | 123.21 | 134.19 | 105.27 | 87.59 | 79.88 | 69.47 | 57.85 | 58.52 | 61.70 | 69.61 | 73.97 | 82.80 | 108.62 | 116.35 | 163.24 | ||||||
| Thermo Fisher Scientific Inc. | 6.03 | 6.12 | 6.19 | 6.09 | 6.25 | 6.03 | 5.62 | 5.62 | 5.53 | 5.54 | 5.98 | 6.64 | 8.28 | 11.56 | 13.59 | 15.70 | 16.73 | ||||||
Based on: 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q1 2026 Calculation
Interest coverage
= (EBITQ1 2026
+ EBITQ4 2025
+ EBITQ3 2025
+ EBITQ2 2025)
÷ (Interest expenseQ1 2026
+ Interest expenseQ4 2025
+ Interest expenseQ3 2025
+ Interest expenseQ2 2025)
= (1,252,900 + 1,334,300 + 1,302,100 + 1,286,700)
÷ (0 + 3,300 + 3,300 + 3,700)
= 502.52
2 Click competitor name to see calculations.
The overall solvency profile demonstrates a significant strengthening of the capacity to service interest obligations over the analyzed period. A long-term upward trajectory in the interest coverage ratio is evident, transitioning from a strong position in early 2022 to an exceptionally high level of coverage by early 2026, despite intermittent periods of volatility.
- Earnings Before Interest and Tax (EBIT) Performance
- EBIT remained generally stable and positive, fluctuating between approximately 900 million and 1.3 billion US dollars for the majority of the period. A notable anomaly occurred in June 2024, where EBIT shifted to a significant negative value of 3.38 billion US dollars. Following this contraction, earnings recovered and stabilized, maintaining a range between 733 million and 1.33 billion US dollars through March 2026.
- Interest Expense Trends
- A consistent and substantial reduction in interest expenses is observed. Costs declined steadily from 14.9 million US dollars in March 2022 to a low of 2.8 million US dollars by December 2024. From 2025 onward, interest expenses remained minimized, fluctuating within a tight band between 3.3 million and 3.7 million US dollars, indicating a significant reduction in the company's debt service burden.
- Interest Coverage Ratio Analysis
- The interest coverage ratio exhibited a strong growth phase from March 2022 (48.17) to March 2024 (111.61), reflecting both rising earnings and falling interest costs. The ratio experienced a sharp decline during the mid-2024 period, dropping to 6.14 and 7.76 in alignment with the negative EBIT spike. Following a further negative fluctuation in March 2025, the ratio entered a phase of exponential growth, climbing from 258.29 in June 2025 to a peak of 502.52 by March 2026.
The convergence of diminishing interest obligations and the recovery of operating earnings has resulted in a solvency position characterized by minimal default risk. The final observations indicate a capacity to cover interest expenses more than 500 times over, representing a profound increase in financial flexibility compared to the baseline in 2022.
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