Analysis of Solvency Ratios
Quarterly Data
Solvency ratios also known as long-term debt ratios measure a company ability to meet long-term obligations.
Solvency Ratios (Summary)
Vertex Pharmaceuticals Inc., solvency ratios (quarterly data)
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
The solvency profile is characterized by an exceptionally conservative capital structure and a minimal reliance on debt financing, although the capacity to service interest payments has exhibited extreme volatility over the analyzed period.
- Debt-to-Equity and Debt-to-Capital Ratios
- A consistent trend of low leverage is observed, with both ratios remaining below 0.11. While these metrics were largely stagnant at 0.02 to 0.03 between March 2022 and March 2024, a marginal increase occurred starting in June 2024, peaking around September 2025. Despite this uptick, the ratios remain very low, indicating that equity remains the primary source of funding.
- Debt-to-Assets Ratio
- The debt-to-assets ratio remained stable within a narrow corridor, fluctuating between 0.02 and 0.08. The relative constancy of this ratio suggests that the growth of the asset base has been mirrored by a similarly low level of debt accumulation, maintaining a strong solvency position.
- Financial Leverage
- Financial leverage remained relatively stable, ranging from 1.28 to 1.44. The lack of significant deviation in this ratio indicates a disciplined approach to asset funding and a low risk of financial instability resulting from over-gearing.
- Interest Coverage Ratio
- The interest coverage ratio demonstrated significant instability. A steady upward trajectory was observed from March 2022 (48.17) through March 2024 (111.61), followed by a sharp contraction to 6.14 in June 2024 and a negative value of -11.94 in March 2025. Following this dip, the ratio experienced an exponential increase, reaching 800.17 by June 2026, signaling an extraordinary capacity to cover interest expenses from operating income in the latter part of the period.
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Debt Ratios
Coverage Ratios
Debt to Equity
Vertex Pharmaceuticals Inc., debt to equity calculation (quarterly data)
| Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||||||||||||||||||||
| Total debt | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | ||||||
| Shareholders’ equity | 20,247,900) | 19,361,900) | 18,665,800) | 17,318,800) | 17,175,400) | 16,496,300) | 16,409,600) | 15,630,900) | 14,774,700) | 18,546,600) | 17,580,400) | 16,512,800) | 15,470,200) | 14,432,300) | 13,912,700) | 13,029,600) | 11,933,500) | 10,907,000) | ||||||
| Solvency Ratio | ||||||||||||||||||||||||
| Debt to equity1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Debt to Equity, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | — | — | — | — | — | 49.22 | 20.19 | 11.78 | 10.42 | 9.24 | 5.73 | 5.02 | 4.74 | 4.68 | 3.67 | 4.35 | 4.98 | 4.51 | ||||||
| Amgen Inc. | 4.90 | 6.24 | 6.31 | 5.67 | 7.57 | 9.24 | 10.23 | 8.02 | 10.57 | 12.75 | 10.37 | 7.90 | 9.08 | 11.52 | 10.64 | 10.60 | 15.10 | 40.23 | ||||||
| Bristol-Myers Squibb Co. | 1.93 | 2.22 | 2.44 | 2.64 | 2.82 | 2.86 | 3.04 | 2.90 | 3.08 | 3.38 | 1.35 | 1.30 | 1.18 | 1.19 | 1.27 | 1.20 | 1.29 | 1.42 | ||||||
| Danaher Corp. | 0.51 | 0.35 | 0.35 | 0.33 | 0.33 | 0.32 | 0.32 | 0.34 | 0.34 | 0.34 | 0.34 | 0.42 | 0.38 | 0.39 | 0.39 | 0.41 | 0.43 | 0.47 | ||||||
| Eli Lilly & Co. | 1.62 | 1.39 | 1.60 | 1.79 | 2.18 | 2.44 | 2.37 | 2.19 | 2.13 | 2.05 | 2.34 | 1.80 | 1.70 | 1.69 | 1.52 | 1.58 | 1.97 | 1.77 | ||||||
| Gilead Sciences Inc. | 2.22 | 0.94 | 1.10 | 1.16 | 1.27 | 1.30 | 1.38 | 1.26 | 1.28 | 1.44 | 1.09 | 1.12 | 1.19 | 1.20 | 1.19 | 1.20 | 1.30 | 1.32 | ||||||
| Johnson & Johnson | 0.58 | 0.68 | 0.59 | 0.58 | 0.65 | 0.67 | 0.51 | 0.51 | 0.58 | 0.48 | 0.43 | 0.42 | 0.61 | 0.75 | 0.52 | 0.43 | 0.43 | 0.44 | ||||||
| Merck & Co. Inc. | 1.29 | 1.07 | 0.94 | 0.80 | 0.72 | 0.72 | 0.80 | 0.86 | 0.87 | 0.85 | 0.93 | 0.85 | 0.95 | 0.66 | 0.67 | 0.68 | 0.73 | 0.78 | ||||||
| Pfizer Inc. | 0.74 | 0.72 | 0.75 | 0.66 | 0.70 | 0.69 | 0.73 | 0.73 | 0.79 | 0.75 | 0.81 | 0.66 | 0.66 | 0.36 | 0.37 | 0.40 | 0.46 | 0.44 | ||||||
| Regeneron Pharmaceuticals Inc. | 0.09 | 0.09 | 0.09 | 0.09 | 0.09 | 0.09 | 0.09 | 0.09 | 0.10 | 0.10 | 0.10 | 0.11 | 0.11 | 0.11 | 0.12 | 0.13 | 0.13 | 0.14 | ||||||
| Thermo Fisher Scientific Inc. | 0.81 | 0.83 | 0.74 | 0.70 | 0.70 | 0.69 | 0.63 | 0.72 | 0.75 | 0.78 | 0.75 | 0.78 | 0.78 | 0.83 | 0.78 | 0.67 | 0.72 | 0.81 | ||||||
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q2 2026 Calculation
Debt to equity = Total debt ÷ Shareholders’ equity
= 0 ÷ 20,247,900 = 0.00
2 Click competitor name to see calculations.
The analysis of solvency metrics reveals a total absence of recorded debt and corresponding debt-to-equity ratios across the entire period from March 31, 2022, to June 30, 2026. This indicates a capital structure that does not utilize interest-bearing debt, resulting in an inherently low-risk solvency profile.
- Shareholders' Equity Growth
- A general upward trend in shareholders' equity is observed, starting at 10.9 billion USD in March 2022 and rising steadily to a peak of 18.5 billion USD by March 31, 2024. This growth suggests a strong accumulation of retained earnings or capital reserves over the initial two-year period.
- Equity Volatility and Recovery
- A significant contraction in shareholders' equity occurred between March 31, 2024, and June 30, 2024, where the value dropped from 18.5 billion USD to 14.7 billion USD. Following this decline, a consistent recovery phase was maintained, with equity growing sequentially every quarter to reach 20.2 billion USD by June 30, 2026.
- Solvency Interpretation
- In the absence of total debt, the debt-to-equity ratio remains null. The reliance on a substantial and growing equity base indicates that the entity's operations are funded entirely through equity, providing a high margin of safety and eliminating the financial risk associated with debt servicing and leverage.
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Debt to Equity (including Operating Lease Liability)
Vertex Pharmaceuticals Inc., debt to equity (including operating lease liability) calculation (quarterly data)
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q2 2026 Calculation
Debt to equity (including operating lease liability) = Total debt (including operating lease liability) ÷ Shareholders’ equity
= 1,977,600 ÷ 20,247,900 = 0.10
The solvency profile exhibits two distinct phases characterized by an initial period of extreme conservatism followed by a strategic shift in capital structure beginning in mid-2024.
- Total Debt Trends
- From March 2022 through March 2024, total debt including operating lease liabilities remained stable, fluctuating within a narrow range between approximately $348 million and $382 million. A significant inflection point occurred in June 2024, where debt increased to $586.8 million, followed by a sharp escalation to $1.589 billion by September 30, 2024. In the subsequent periods leading to June 2026, debt levels continued to rise, peaking at $1.987 billion in December 2025 before settling at $1.978 billion.
- Shareholders' Equity Evolution
- Equity demonstrated a consistent upward trajectory from $10.9 billion in March 2022 to $18.5 billion in March 2024. A notable contraction occurred in June 2024, with equity decreasing to $14.77 billion. Following this decline, a steady recovery trend resumed, with equity growing to reach $20.25 billion by June 30, 2026.
- Debt to Equity Ratio Analysis
- The debt to equity ratio was maintained at a negligible level of 0.02 to 0.03 during the first two years of the analysis. The shift in leverage began in June 2024, coinciding with the increase in total debt and the contraction of equity, pushing the ratio to 0.04. By September 2024, the ratio spiked to 0.10. Throughout the remainder of the period, the ratio stabilized between 0.09 and 0.11, indicating a transition to a higher, yet still conservative, leverage position.
Overall, the financial structure transitioned from a near-zero debt model to a more leveraged position starting in 2024. Despite the substantial increase in total liabilities, the simultaneous growth in shareholders' equity has maintained the solvency ratio at a low level, suggesting a robust capacity to manage the increased debt load.
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Debt to Capital
Vertex Pharmaceuticals Inc., debt to capital calculation (quarterly data)
| Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||||||||||||||||||||
| Total debt | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | ||||||
| Shareholders’ equity | 20,247,900) | 19,361,900) | 18,665,800) | 17,318,800) | 17,175,400) | 16,496,300) | 16,409,600) | 15,630,900) | 14,774,700) | 18,546,600) | 17,580,400) | 16,512,800) | 15,470,200) | 14,432,300) | 13,912,700) | 13,029,600) | 11,933,500) | 10,907,000) | ||||||
| Total capital | 20,247,900) | 19,361,900) | 18,665,800) | 17,318,800) | 17,175,400) | 16,496,300) | 16,409,600) | 15,630,900) | 14,774,700) | 18,546,600) | 17,580,400) | 16,512,800) | 15,470,200) | 14,432,300) | 13,912,700) | 13,029,600) | 11,933,500) | 10,907,000) | ||||||
| Solvency Ratio | ||||||||||||||||||||||||
| Debt to capital1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Debt to Capital, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 1.09 | 1.10 | 1.05 | 1.04 | 1.00 | 0.98 | 0.95 | 0.92 | 0.91 | 0.90 | 0.85 | 0.83 | 0.83 | 0.82 | 0.79 | 0.81 | 0.83 | 0.82 | ||||||
| Amgen Inc. | 0.83 | 0.86 | 0.86 | 0.85 | 0.88 | 0.90 | 0.91 | 0.89 | 0.91 | 0.93 | 0.91 | 0.89 | 0.90 | 0.92 | 0.91 | 0.91 | 0.94 | 0.98 | ||||||
| Bristol-Myers Squibb Co. | 0.66 | 0.69 | 0.71 | 0.73 | 0.74 | 0.74 | 0.75 | 0.74 | 0.75 | 0.77 | 0.57 | 0.56 | 0.54 | 0.54 | 0.56 | 0.54 | 0.56 | 0.59 | ||||||
| Danaher Corp. | 0.34 | 0.26 | 0.26 | 0.25 | 0.25 | 0.24 | 0.24 | 0.25 | 0.25 | 0.25 | 0.26 | 0.30 | 0.28 | 0.28 | 0.28 | 0.29 | 0.30 | 0.32 | ||||||
| Eli Lilly & Co. | 0.62 | 0.58 | 0.62 | 0.64 | 0.69 | 0.71 | 0.70 | 0.69 | 0.68 | 0.67 | 0.70 | 0.64 | 0.63 | 0.63 | 0.60 | 0.61 | 0.66 | 0.64 | ||||||
| Gilead Sciences Inc. | 0.69 | 0.49 | 0.52 | 0.54 | 0.56 | 0.57 | 0.58 | 0.56 | 0.56 | 0.59 | 0.52 | 0.53 | 0.54 | 0.55 | 0.54 | 0.54 | 0.56 | 0.57 | ||||||
| Johnson & Johnson | 0.37 | 0.40 | 0.37 | 0.37 | 0.39 | 0.40 | 0.34 | 0.34 | 0.37 | 0.32 | 0.30 | 0.30 | 0.38 | 0.43 | 0.34 | 0.30 | 0.30 | 0.31 | ||||||
| Merck & Co. Inc. | 0.56 | 0.52 | 0.48 | 0.44 | 0.42 | 0.42 | 0.44 | 0.46 | 0.46 | 0.46 | 0.48 | 0.46 | 0.49 | 0.40 | 0.40 | 0.41 | 0.42 | 0.44 | ||||||
| Pfizer Inc. | 0.43 | 0.42 | 0.43 | 0.40 | 0.41 | 0.41 | 0.42 | 0.42 | 0.44 | 0.43 | 0.45 | 0.40 | 0.40 | 0.26 | 0.27 | 0.28 | 0.32 | 0.31 | ||||||
| Regeneron Pharmaceuticals Inc. | 0.08 | 0.08 | 0.08 | 0.08 | 0.08 | 0.08 | 0.08 | 0.08 | 0.09 | 0.09 | 0.09 | 0.10 | 0.10 | 0.10 | 0.11 | 0.11 | 0.12 | 0.12 | ||||||
| Thermo Fisher Scientific Inc. | 0.45 | 0.45 | 0.42 | 0.41 | 0.41 | 0.41 | 0.39 | 0.42 | 0.43 | 0.44 | 0.43 | 0.44 | 0.44 | 0.45 | 0.44 | 0.40 | 0.42 | 0.45 | ||||||
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q2 2026 Calculation
Debt to capital = Total debt ÷ Total capital
= 0 ÷ 20,247,900 = 0.00
2 Click competitor name to see calculations.
An analysis of the solvency metrics reveals that total debt figures are not recorded for the period from March 31, 2022, through June 30, 2026. Consequently, the debt-to-capital ratio cannot be calculated or evaluated based on the available information.
- Total Capital Expansion
- A consistent upward trend in total capital is observed from March 31, 2022, through March 31, 2024. During this timeframe, total capital increased from 10,907,000 thousand USD to a peak of 18,546,600 thousand USD, indicating a period of steady capitalization growth.
- Capital Contraction and Recovery
- A significant reduction in total capital occurred on June 30, 2024, where the value decreased to 14,774,700 thousand USD. Following this decline, a sustained recovery trend is evident, with capital increasing incrementally in subsequent quarters to reach 20,247,900 thousand USD by June 30, 2026.
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Debt to Capital (including Operating Lease Liability)
Vertex Pharmaceuticals Inc., debt to capital (including operating lease liability) calculation (quarterly data)
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q2 2026 Calculation
Debt to capital (including operating lease liability) = Total debt (including operating lease liability) ÷ Total capital (including operating lease liability)
= 1,977,600 ÷ 22,225,500 = 0.09
The solvency profile exhibits two distinct phases: a period of minimal leverage followed by a strategic increase in debt obligations starting in mid-2024.
- Total Debt Trends
- From March 2022 through March 2024, total debt, including operating lease liabilities, remained relatively stagnant, fluctuating within a narrow range between 348.6 million and 382.3 million US dollars. A significant escalation occurred between June 2024 and September 2024, where debt levels rose from 586.8 million to 1.588 billion US dollars. This upward trajectory continued through June 2026, peaking at 1.986 billion US dollars in December 2025.
- Total Capital Evolution
- Total capital demonstrated a consistent long-term expansion, growing from 11.284 billion US dollars in March 2022 to 22.225 billion US dollars by June 2026. Despite a temporary contraction in June 2024 to 15.361 billion US dollars, the overall trend indicates a sustained increase in the total capital base, which has scaled alongside the increased debt levels.
- Debt to Capital Ratio Analysis
- The debt to capital ratio remained exceptionally low and stable between 0.02 and 0.03 for the first two years of the period. Following the debt increase in 2024, the ratio shifted to a higher baseline, fluctuating between 0.08 and 0.10. While the relative leverage increased, the ratio of 0.09 observed through June 2026 indicates that debt continues to constitute a small fraction of the total capital structure, reflecting a conservative solvency position despite the increased borrowing.
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Debt to Assets
Vertex Pharmaceuticals Inc., debt to assets calculation (quarterly data)
| Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||||||||||||||||||||
| Total debt | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | —) | ||||||
| Total assets | 27,423,300) | 26,484,400) | 25,643,000) | 24,862,300) | 24,036,700) | 22,880,500) | 22,533,200) | 22,240,200) | 20,132,100) | 23,917,400) | 22,730,200) | 21,726,200) | 20,349,200) | 18,974,200) | 18,150,900) | 16,706,400) | 15,582,200) | 14,256,100) | ||||||
| Solvency Ratio | ||||||||||||||||||||||||
| Debt to assets1 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Debt to Assets, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | 0.52 | 0.53 | 0.50 | 0.51 | 0.51 | 0.51 | 0.50 | 0.50 | 0.50 | 0.50 | 0.44 | 0.45 | 0.45 | 0.46 | 0.46 | 0.49 | 0.51 | 0.51 | ||||||
| Amgen Inc. | 0.60 | 0.62 | 0.60 | 0.61 | 0.64 | 0.64 | 0.65 | 0.66 | 0.69 | 0.69 | 0.67 | 0.67 | 0.68 | 0.69 | 0.60 | 0.61 | 0.62 | 0.62 | ||||||
| Bristol-Myers Squibb Co. | 0.49 | 0.51 | 0.50 | 0.51 | 0.52 | 0.54 | 0.54 | 0.53 | 0.55 | 0.56 | 0.42 | 0.41 | 0.40 | 0.40 | 0.41 | 0.40 | 0.42 | 0.44 | ||||||
| Danaher Corp. | 0.29 | 0.22 | 0.22 | 0.21 | 0.21 | 0.21 | 0.21 | 0.22 | 0.22 | 0.22 | 0.22 | 0.25 | 0.23 | 0.23 | 0.23 | 0.24 | 0.25 | 0.26 | ||||||
| Eli Lilly & Co. | 0.39 | 0.37 | 0.38 | 0.37 | 0.40 | 0.43 | 0.43 | 0.41 | 0.40 | 0.41 | 0.39 | 0.35 | 0.34 | 0.36 | 0.33 | 0.33 | 0.36 | 0.35 | ||||||
| Gilead Sciences Inc. | 0.53 | 0.39 | 0.42 | 0.43 | 0.45 | 0.44 | 0.45 | 0.43 | 0.44 | 0.45 | 0.40 | 0.40 | 0.40 | 0.41 | 0.40 | 0.40 | 0.42 | 0.42 | ||||||
| Johnson & Johnson | 0.24 | 0.27 | 0.24 | 0.24 | 0.26 | 0.27 | 0.20 | 0.20 | 0.23 | 0.20 | 0.18 | 0.18 | 0.24 | 0.27 | 0.21 | 0.18 | 0.18 | 0.19 | ||||||
| Merck & Co. Inc. | 0.42 | 0.38 | 0.36 | 0.32 | 0.30 | 0.30 | 0.32 | 0.32 | 0.34 | 0.32 | 0.33 | 0.33 | 0.35 | 0.29 | 0.28 | 0.28 | 0.30 | 0.30 | ||||||
| Pfizer Inc. | 0.31 | 0.31 | 0.31 | 0.30 | 0.30 | 0.30 | 0.30 | 0.31 | 0.32 | 0.31 | 0.32 | 0.30 | 0.30 | 0.18 | 0.18 | 0.19 | 0.21 | 0.20 | ||||||
| Regeneron Pharmaceuticals Inc. | 0.06 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.07 | 0.08 | 0.08 | 0.08 | 0.09 | 0.09 | 0.09 | 0.10 | 0.10 | 0.10 | ||||||
| Thermo Fisher Scientific Inc. | 0.38 | 0.38 | 0.36 | 0.35 | 0.35 | 0.35 | 0.32 | 0.35 | 0.36 | 0.37 | 0.35 | 0.36 | 0.36 | 0.37 | 0.35 | 0.32 | 0.33 | 0.36 | ||||||
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q2 2026 Calculation
Debt to assets = Total debt ÷ Total assets
= 0 ÷ 27,423,300 = 0.00
2 Click competitor name to see calculations.
The available financial data is insufficient to perform a quantitative analysis of the debt-to-assets ratio, as total debt figures are not present for the period spanning March 31, 2022, to June 30, 2026. Consequently, the specific solvency metric requested cannot be calculated. However, the trend in total assets provides insight into the company's overall scale and resource base during this timeframe.
- Total Asset Trajectory
- A sustained upward trend in total assets is observed for the majority of the period. Assets grew from 14.26 billion on March 31, 2022, to a peak of 23.92 billion by March 31, 2024. Following a temporary decline, the growth resumed, ending at 27.42 billion on June 30, 2026.
- Asset Volatility
- A significant contraction in total assets occurred on June 30, 2024, where the value dropped to 20.13 billion from the previous quarter's 23.92 billion. This represents a sharp but transient decrease before the asset base began a consistent recovery and expansion phase through the end of the reported period.
- Solvency Analysis Limitation
- Because the total debt values are missing across all quarters, the debt-to-assets ratio remains undetermined. It is therefore not possible to assess the degree of financial leverage or the proportion of assets funded by creditors versus shareholders.
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Debt to Assets (including Operating Lease Liability)
Vertex Pharmaceuticals Inc., debt to assets (including operating lease liability) calculation (quarterly data)
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q2 2026 Calculation
Debt to assets (including operating lease liability) = Total debt (including operating lease liability) ÷ Total assets
= 1,977,600 ÷ 27,423,300 = 0.07
The financial solvency profile exhibits two distinct phases: a period of extreme conservatism followed by a strategic increase in leverage beginning in mid-2024. Despite the significant increase in total obligations, the overall solvency remains robust, characterized by a low reliance on debt relative to the total asset base.
- Total Debt Trends
- Between March 2022 and March 2024, total debt remained relatively stable, fluctuating within a narrow range between 348.6 million and 382.3 million. A sharp inflection point occurred in June 2024, with debt rising to 586.8 million, followed by a substantial surge to 1.588 billion by September 2024. This elevated debt level persisted through 2025, with further increases leading to a peak of 1.986 billion by December 2025, before stabilizing at 1.977 billion in June 2026.
- Total Asset Trajectory
- Total assets demonstrated a consistent upward trend from 14.256 billion in March 2022 to 23.917 billion in March 2024. A temporary contraction to 20.132 billion was observed in June 2024, coinciding with the initial increase in debt. Subsequent recovery and steady growth followed, with assets expanding to 27.423 billion by June 2026, reflecting a strong growth in the company's resource base.
- Debt to Assets Ratio Analysis
- The debt to assets ratio remained minimal, ranging between 0.02 and 0.03 from March 2022 through March 2024. The ratio shifted upward to 0.07 in September 2024, directly reflecting the increased borrowing. Throughout the remainder of the analyzed period, the ratio fluctuated between 0.06 and 0.08, peaking at 0.08 in March 2026. This indicates that while leverage has increased, the total asset base continues to provide substantial coverage for all liabilities, maintaining a high level of financial solvency.
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Financial Leverage
Vertex Pharmaceuticals Inc., financial leverage calculation (quarterly data)
| Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||||||||||||||||||||
| Total assets | 27,423,300) | 26,484,400) | 25,643,000) | 24,862,300) | 24,036,700) | 22,880,500) | 22,533,200) | 22,240,200) | 20,132,100) | 23,917,400) | 22,730,200) | 21,726,200) | 20,349,200) | 18,974,200) | 18,150,900) | 16,706,400) | 15,582,200) | 14,256,100) | ||||||
| Shareholders’ equity | 20,247,900) | 19,361,900) | 18,665,800) | 17,318,800) | 17,175,400) | 16,496,300) | 16,409,600) | 15,630,900) | 14,774,700) | 18,546,600) | 17,580,400) | 16,512,800) | 15,470,200) | 14,432,300) | 13,912,700) | 13,029,600) | 11,933,500) | 10,907,000) | ||||||
| Solvency Ratio | ||||||||||||||||||||||||
| Financial leverage1 | 1.35 | 1.37 | 1.37 | 1.44 | 1.40 | 1.39 | 1.37 | 1.42 | 1.36 | 1.29 | 1.29 | 1.32 | 1.32 | 1.31 | 1.30 | 1.28 | 1.31 | 1.31 | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Financial Leverage, Competitors2 | ||||||||||||||||||||||||
| AbbVie Inc. | — | — | — | — | — | 95.89 | 40.65 | 23.78 | 20.94 | 18.59 | 13.00 | 11.26 | 10.52 | 10.14 | 8.04 | 8.84 | 9.77 | 8.80 | ||||||
| Amgen Inc. | 8.18 | 10.07 | 10.46 | 9.37 | 11.83 | 14.40 | 15.63 | 12.07 | 15.34 | 18.51 | 15.59 | 11.83 | 13.31 | 16.59 | 17.79 | 17.44 | 24.51 | 64.62 | ||||||
| Bristol-Myers Squibb Co. | 3.93 | 4.31 | 4.87 | 5.22 | 5.43 | 5.32 | 5.67 | 5.46 | 5.56 | 6.01 | 3.23 | 3.15 | 2.92 | 2.96 | 3.12 | 3.01 | 3.08 | 3.26 | ||||||
| Danaher Corp. | 1.76 | 1.58 | 1.59 | 1.56 | 1.56 | 1.56 | 1.57 | 1.57 | 1.57 | 1.56 | 1.58 | 1.67 | 1.64 | 1.65 | 1.68 | 1.72 | 1.76 | 1.80 | ||||||
| Eli Lilly & Co. | 4.20 | 3.74 | 4.24 | 4.83 | 5.52 | 5.67 | 5.55 | 5.31 | 5.30 | 4.99 | 5.94 | 5.16 | 4.95 | 4.75 | 4.65 | 4.71 | 5.51 | 5.03 | ||||||
| Gilead Sciences Inc. | 4.17 | 2.39 | 2.60 | 2.72 | 2.83 | 2.95 | 3.05 | 2.95 | 2.93 | 3.21 | 2.72 | 2.80 | 2.95 | 2.95 | 2.97 | 2.97 | 3.11 | 3.17 | ||||||
| Johnson & Johnson | 2.37 | 2.47 | 2.44 | 2.43 | 2.46 | 2.48 | 2.52 | 2.54 | 2.53 | 2.46 | 2.44 | 2.33 | 2.55 | 2.77 | 2.44 | 2.35 | 2.33 | 2.39 | ||||||
| Merck & Co. Inc. | 3.10 | 2.80 | 2.60 | 2.50 | 2.40 | 2.38 | 2.53 | 2.64 | 2.58 | 2.62 | 2.84 | 2.59 | 2.70 | 2.30 | 2.37 | 2.41 | 2.48 | 2.61 | ||||||
| Pfizer Inc. | 2.36 | 2.30 | 2.41 | 2.25 | 2.32 | 2.30 | 2.42 | 2.38 | 2.47 | 2.40 | 2.54 | 2.22 | 2.22 | 1.94 | 2.06 | 2.10 | 2.24 | 2.23 | ||||||
| Regeneron Pharmaceuticals Inc. | 1.32 | 1.30 | 1.30 | 1.30 | 1.28 | 1.28 | 1.29 | 1.28 | 1.28 | 1.27 | 1.27 | 1.29 | 1.28 | 1.28 | 1.29 | 1.29 | 1.32 | 1.32 | ||||||
| Thermo Fisher Scientific Inc. | 2.15 | 2.18 | 2.07 | 2.02 | 2.00 | 2.01 | 1.96 | 2.05 | 2.08 | 2.13 | 2.11 | 2.14 | 2.15 | 2.24 | 2.21 | 2.08 | 2.14 | 2.26 | ||||||
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q2 2026 Calculation
Financial leverage = Total assets ÷ Shareholders’ equity
= 27,423,300 ÷ 20,247,900 = 1.35
2 Click competitor name to see calculations.
The financial position reflects a sustained period of balance sheet expansion from March 2022 through March 2024, followed by a notable contraction in the second quarter of 2024 and a subsequent recovery phase extending through June 2026.
- Asset and Equity Growth Trajectory
- Total assets increased steadily from 14.26 billion in March 2022 to a peak of 23.92 billion by March 2024. This upward trend was mirrored by shareholders' equity, which rose from 10.91 billion to 18.55 billion over the same period, indicating a strong accumulation of net assets.
- Analysis of the 2024 Balance Sheet Contraction
- A significant reduction in balance sheet size occurred in June 2024, where total assets decreased to 20.13 billion and shareholders' equity fell to 14.77 billion. Following this event, a consistent recovery trend is observed, with total assets reaching 27.42 billion and shareholders' equity ascending to 20.25 billion by June 2026.
- Financial Leverage Dynamics
- For the first two years of the observed period, the financial leverage ratio remained highly stable, fluctuating narrowly between 1.28 and 1.32. A structural shift occurred in mid-2024; coinciding with the contraction of equity and assets, the leverage ratio climbed to a peak of 1.42 in September 2024. In the final period from December 2024 to June 2026, the ratio stabilized at a higher plateau, generally ranging between 1.35 and 1.44, suggesting a relative increase in the proportion of debt or liabilities compared to equity.
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Interest Coverage
Vertex Pharmaceuticals Inc., interest coverage calculation (quarterly data)
| Jun 30, 2026 | Mar 31, 2026 | Dec 31, 2025 | Sep 30, 2025 | Jun 30, 2025 | Mar 31, 2025 | Dec 31, 2024 | Sep 30, 2024 | Jun 30, 2024 | Mar 31, 2024 | Dec 31, 2023 | Sep 30, 2023 | Jun 30, 2023 | Mar 31, 2023 | Dec 31, 2022 | Sep 30, 2022 | Jun 30, 2022 | Mar 31, 2022 | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selected Financial Data (US$ in thousands) | ||||||||||||||||||||||||
| Net income (loss) | 1,099,800) | 1,031,400) | 1,191,100) | 1,082,900) | 1,032,900) | 646,300) | 913,000) | 1,045,400) | (3,593,600) | 1,099,600) | 968,800) | 1,035,300) | 915,700) | 699,800) | 818,900) | 930,500) | 810,500) | 762,100) | ||||||
| Add: Income tax expense | 292,000) | 221,500) | 139,900) | 215,900) | 250,100) | 84,100) | 223,500) | 178,700) | 202,400) | 179,500) | 178,800) | 143,900) | 245,800) | 191,700) | 257,900) | 245,900) | 213,900) | 192,700) | ||||||
| Add: Interest expense | —) | —) | 3,300) | 3,300) | 3,700) | 3,000) | 2,800) | 7,500) | 9,900) | 10,400) | 10,600) | 10,900) | 11,200) | 11,400) | 11,600) | 13,700) | 14,600) | 14,900) | ||||||
| Earnings before interest and tax (EBIT) | 1,391,800) | 1,252,900) | 1,334,300) | 1,302,100) | 1,286,700) | 733,400) | 1,139,300) | 1,231,600) | (3,381,300) | 1,289,500) | 1,158,200) | 1,190,100) | 1,172,700) | 902,900) | 1,088,400) | 1,190,100) | 1,039,000) | 969,700) | ||||||
| Solvency Ratio | ||||||||||||||||||||||||
| Interest coverage1 | 800.17 | 502.52 | 350.11 | 348.55 | 258.29 | -11.94 | 9.12 | 7.76 | 6.14 | 111.61 | 100.32 | 96.54 | 90.90 | 82.27 | 78.23 | 70.08 | 66.72 | 48.17 | ||||||
| Benchmarks | ||||||||||||||||||||||||
| Interest Coverage, Competitors2 | ||||||||||||||||||||||||
| Amgen Inc. | 4.86 | 4.38 | 4.26 | 3.89 | 3.53 | 3.18 | 2.46 | 2.45 | 2.10 | 2.38 | 3.73 | 4.54 | 5.43 | 6.51 | 6.22 | 6.83 | 6.97 | 6.40 | ||||||
| Danaher Corp. | 17.31 | 17.95 | 16.97 | 16.41 | 15.01 | 16.80 | 17.71 | 16.11 | 17.61 | 17.81 | 18.64 | 23.66 | 29.65 | 35.60 | 40.30 | 41.32 | 35.26 | 33.54 | ||||||
| Gilead Sciences Inc. | -0.96 | 11.68 | 10.57 | 10.71 | 8.20 | 7.94 | 1.71 | 1.18 | 2.58 | 2.11 | 8.27 | 8.88 | 9.03 | 8.84 | 7.22 | 5.80 | 6.73 | 6.97 | ||||||
| Johnson & Johnson | 25.90 | 25.00 | 34.55 | 36.24 | 33.48 | 34.09 | 23.10 | 23.92 | 26.40 | 29.06 | 20.51 | 19.09 | 23.89 | 31.49 | 79.71 | 141.63 | 160.27 | 164.15 | ||||||
| Regeneron Pharmaceuticals Inc. | 94.25 | 108.44 | 120.42 | 123.21 | 134.19 | 105.27 | 87.59 | 79.88 | 69.47 | 57.85 | 58.52 | 61.70 | 69.61 | 73.97 | 82.80 | 108.62 | 116.35 | 163.24 | ||||||
| Thermo Fisher Scientific Inc. | 6.17 | 6.03 | 6.12 | 6.19 | 6.09 | 6.25 | 6.03 | 5.62 | 5.62 | 5.53 | 5.54 | 5.98 | 6.64 | 8.28 | 11.56 | 13.59 | 15.70 | 16.73 | ||||||
Based on: 10-Q (reporting date: 2026-06-30), 10-Q (reporting date: 2026-03-31), 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).
1 Q2 2026 Calculation
Interest coverage
= (EBITQ2 2026
+ EBITQ1 2026
+ EBITQ4 2025
+ EBITQ3 2025)
÷ (Interest expenseQ2 2026
+ Interest expenseQ1 2026
+ Interest expenseQ4 2025
+ Interest expenseQ3 2025)
= (1,391,800 + 1,252,900 + 1,334,300 + 1,302,100)
÷ (0 + 0 + 3,300 + 3,300)
= 800.17
2 Click competitor name to see calculations.
An analysis of solvency metrics reveals a general strengthening of the ability to service debt obligations over the observed period, characterized by a significant long-term upward trend in the interest coverage ratio despite a period of acute volatility in 2024 and early 2025.
- Interest Coverage Ratio Trends
- The interest coverage ratio exhibited a consistent climb from 48.17 in March 2022 to a peak of 111.61 by March 2024, indicating a robust increase in the margin of safety for debt servicing. A severe contraction followed, with the ratio falling to 6.14 in June 2024 and reaching a negative value of -11.94 by March 2025. However, a rapid recovery ensued, with the ratio expanding aggressively from June 2025 onwards, ultimately reaching 800.17 by June 2026.
- Earnings Before Interest and Tax (EBIT) Performance
- Operational earnings generally trended upward, starting at 969,700 thousand US$ in March 2022 and reaching 1,391,800 thousand US$ by June 2026. This growth was interrupted by a substantial negative outlier in June 2024, where EBIT dropped to -3,381,300 thousand US$. Following this volatility, earnings stabilized and resumed a growth trajectory, consistently exceeding 1.2 billion US$ from September 2025 through June 2026.
- Interest Expense Dynamics
- A sustained downward trend in interest expenses is observed throughout the period. Expenses decreased from 14,900 thousand US$ in March 2022 to a low of 2,800 thousand US$ in December 2024. For the remainder of the analysis period, interest costs remained low and stable, fluctuating between 3,000 and 3,700 thousand US$, which contributed significantly to the expansion of the interest coverage ratio in the later quarters.
The convergence of declining interest expenses and recovering operational earnings resulted in an exceptional solvency position by mid-2026, effectively neutralizing the risks observed during the 2024 earnings contraction.
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