Stock Analysis on Net

Pfizer Inc. (NYSE:PFE)

Analysis of Solvency Ratios 
Quarterly Data

Microsoft Excel

Solvency Ratios (Summary)

Pfizer Inc., solvency ratios (quarterly data)

Microsoft Excel
Sep 28, 2025 Jun 29, 2025 Mar 30, 2025 Dec 31, 2024 Sep 29, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Oct 1, 2023 Jul 2, 2023 Apr 2, 2023 Dec 31, 2022 Oct 2, 2022 Jul 3, 2022 Apr 3, 2022 Dec 31, 2021 Oct 3, 2021 Jul 4, 2021 Apr 4, 2021
Debt Ratios
Debt to equity 0.66 0.70 0.69 0.73 0.73 0.79 0.75 0.81 0.66 0.66 0.36 0.37 0.40 0.46 0.44 0.50 0.53 0.56 0.58
Debt to capital 0.40 0.41 0.41 0.42 0.42 0.44 0.43 0.45 0.40 0.40 0.26 0.27 0.28 0.32 0.31 0.33 0.35 0.36 0.37
Debt to assets 0.30 0.30 0.30 0.30 0.31 0.32 0.31 0.32 0.30 0.30 0.18 0.18 0.19 0.21 0.20 0.21 0.22 0.23 0.25
Financial leverage 2.25 2.32 2.30 2.42 2.38 2.47 2.40 2.54 2.22 2.22 1.94 2.06 2.10 2.24 2.23 2.35 2.37 2.43 2.31

Based on: 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-10-03), 10-Q (reporting date: 2021-07-04), 10-Q (reporting date: 2021-04-04).


The analysis of the financial leverage and debt ratios over multiple quarters reveals several key trends regarding the company's capital structure and risk profile.

Debt to Equity Ratio
The debt to equity ratio shows a declining trend from 0.58 in early April 2021 to a low of 0.36 by April 2023, indicating a reduction in reliance on debt relative to equity during this period. However, beginning in mid-2023, the ratio rises sharply, reaching a peak of 0.81 by the end of December 2023, before stabilizing around the mid-0.7 range through mid-2025. This suggests an increased use of debt financing or a decrease in equity during late 2023, followed by a moderation of this leverage.
Debt to Capital Ratio
The debt to capital ratio follows a similar trajectory, decreasing steadily from 0.37 in April 2021 to approximately 0.26 in April 2023, reflecting a more conservative capital structure. Afterward, the ratio increases notably, reaching 0.45 by December 2023, before mildly decreasing and stabilizing around 0.40 through mid-2025. This pattern confirms the earlier observation of increased debt utilization in late 2023, which then slightly retreats and remains elevated relative to the initial period.
Debt to Assets Ratio
The debt to assets ratio exhibits a consistent downward trend from 0.25 in early 2021 to a nadir of 0.18 by April 2023, implying reduced overall leverage relative to total assets. Subsequently, this ratio rises significantly to 0.32 at the end of 2023 and then hovers around 0.30 through mid-2025, suggesting an increased burden of debt on the company’s asset base beginning in late 2023, consistent with the other debt ratios.
Financial Leverage Ratio
The financial leverage ratio initially declines from 2.31 in April 2021 to 1.94 in April 2023, reflecting a gradual reduction in the company’s use of borrowings relative to equity. However, this ratio increases considerably toward the end of 2023 to 2.54, marking the highest point in the observed periods, after which it slowly diminishes but remains relatively elevated near 2.25 through mid-2025. This confirms a temporary increase in leverage around late 2023, followed by a partial reduction.

Overall, the data illustrates an extended period of deleveraging and strengthening equity from 2021 to early 2023. In late 2023, the company notably increased its leverage across multiple metrics, resulting in heightened financial risk for a brief period. After this spike, leverage measures generally plateau at levels higher than their previous lows but lower than their late-2023 peaks. These trends may reflect strategic financing decisions, possibly driven by capital expenditures, acquisitions, or market conditions influencing capital structure.


Debt Ratios


Debt to Equity

Pfizer Inc., debt to equity calculation (quarterly data)

Microsoft Excel
Sep 28, 2025 Jun 29, 2025 Mar 30, 2025 Dec 31, 2024 Sep 29, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Oct 1, 2023 Jul 2, 2023 Apr 2, 2023 Dec 31, 2022 Oct 2, 2022 Jul 3, 2022 Apr 3, 2022 Dec 31, 2021 Oct 3, 2021 Jul 4, 2021 Apr 4, 2021
Selected Financial Data (US$ in millions)
Short-term borrowings, including current portion of long-term debt 4,303 4,295 4,470 6,946 9,699 11,944 8,232 10,350 2,548 3,985 4,188 2,945 4,040 5,990 645 2,241 3,629 3,888 4,352
Long-term debt, excluding current portion 57,409 57,502 57,639 57,405 58,002 57,506 61,307 61,538 61,048 61,356 31,704 32,884 32,629 34,294 35,656 36,195 36,250 35,354 35,347
Total debt 61,712 61,797 62,109 64,351 67,701 69,450 69,539 71,888 63,596 65,341 35,892 35,829 36,669 40,284 36,301 38,436 39,879 39,242 39,699
 
Total Pfizer Inc. shareholders’ equity 92,801 88,695 90,338 88,203 92,286 87,700 92,282 89,014 96,934 99,019 100,970 95,661 92,631 87,208 82,424 77,201 75,691 70,042 68,620
Solvency Ratio
Debt to equity1 0.66 0.70 0.69 0.73 0.73 0.79 0.75 0.81 0.66 0.66 0.36 0.37 0.40 0.46 0.44 0.50 0.53 0.56 0.58
Benchmarks
Debt to Equity, Competitors2
AbbVie Inc. 49.22 20.19 11.78 10.42 9.24 5.73 5.02 4.74 4.68 3.67 4.35 4.98 4.51 4.98 5.96 6.53 6.24
Amgen Inc. 5.67 7.57 9.24 10.23 8.02 10.57 12.75 10.37 7.90 9.08 11.52 10.64 10.60 15.10 40.23 4.97 4.57 3.98 3.50
Bristol-Myers Squibb Co. 2.64 2.82 2.86 3.04 2.90 3.08 3.38 1.35 1.30 1.18 1.19 1.27 1.20 1.29 1.42 1.24 1.20 1.23 1.23
Danaher Corp. 0.33 0.33 0.32 0.32 0.34 0.34 0.34 0.34 0.42 0.38 0.39 0.39 0.41 0.43 0.47 0.49 0.54 0.48 0.50
Eli Lilly & Co. 1.79 2.18 2.44 2.37 2.19 2.13 2.05 2.34 1.80 1.70 1.69 1.52 1.58 1.97 1.77 1.88 2.20 2.56 2.35
Gilead Sciences Inc. 1.27 1.30 1.38 1.26 1.28 1.44 1.09 1.12 1.19 1.20 1.19 1.20 1.30 1.32 1.27 1.29 1.53 1.59
Johnson & Johnson 0.58 0.65 0.67 0.51 0.51 0.58 0.48 0.43 0.42 0.61 0.75 0.52 0.43 0.43 0.44 0.46 0.48 0.48 0.51
Merck & Co. Inc. 0.80 0.72 0.72 0.80 0.86 0.87 0.85 0.93 0.85 0.95 0.66 0.67 0.68 0.73 0.78 0.87 0.74 0.80 1.16
Regeneron Pharmaceuticals Inc. 0.09 0.09 0.09 0.09 0.09 0.10 0.10 0.10 0.11 0.11 0.11 0.12 0.13 0.13 0.14 0.14 0.16 0.18 0.23
Thermo Fisher Scientific Inc. 0.70 0.70 0.69 0.63 0.72 0.75 0.78 0.75 0.78 0.78 0.83 0.78 0.67 0.72 0.81 0.85 0.56 0.51 0.53
Vertex Pharmaceuticals Inc. 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00

Based on: 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-10-03), 10-Q (reporting date: 2021-07-04), 10-Q (reporting date: 2021-04-04).

1 Q3 2025 Calculation
Debt to equity = Total debt ÷ Total Pfizer Inc. shareholders’ equity
= 61,712 ÷ 92,801 = 0.66

2 Click competitor name to see calculations.


Total Debt
The total debt exhibits a fluctuating trend over the observed periods. Initially, it decreases moderately from approximately 39,699 million USD to 35,829 million USD by the end of 2022. Subsequently, a significant rise is observed starting in the first quarter of 2023, peaking at around 71,888 million USD in the fourth quarter of 2023. Following this peak, the debt level consistently declines through to the third quarter of 2025, reaching approximately 61,712 million USD.
Total Shareholders' Equity
Shareholders’ equity demonstrates a general upward trend from early 2021 through the first quarter of 2023, increasing from about 68,620 million USD to a peak near 100,970 million USD. After this peak, equity declines somewhat, hovering between roughly 89,014 million USD and 92,286 million USD in the subsequent quarters through the end of 2024. In 2025, it shows modest fluctuations, ultimately ending near 92,801 million USD at mid-2025.
Debt to Equity Ratio
The debt-to-equity ratio reveals a decreasing pattern from 0.58 in early 2021 to a low point around 0.36 by early 2023, indicating a strengthening equity position relative to debt during this period. However, from 2023 onward, the ratio experiences a marked increase, reaching a high of 0.81 in late 2023. This indicates a rising proportion of debt compared to equity. Following this peak, the ratio declines gradually, stabilizing around 0.66 by mid-2025.
Summary Insights
Over the examined timeframe, the company managed to reduce debt and grow equity steadily until early 2023, improving its financial leverage position. From 2023 onwards, a pronounced increase in debt levels and the associated debt-to-equity ratio suggests heightened leverage, potentially due to financing activities or acquisitions. Despite this, shareholders’ equity remains relatively stable in the mid to high 90-billion USD range after an initial peak. The gradual decline of debt after the peak and the concurrent stabilization of the debt-to-equity ratio indicate efforts to manage leverage and maintain a balanced capital structure in recent periods.

Debt to Capital

Pfizer Inc., debt to capital calculation (quarterly data)

Microsoft Excel
Sep 28, 2025 Jun 29, 2025 Mar 30, 2025 Dec 31, 2024 Sep 29, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Oct 1, 2023 Jul 2, 2023 Apr 2, 2023 Dec 31, 2022 Oct 2, 2022 Jul 3, 2022 Apr 3, 2022 Dec 31, 2021 Oct 3, 2021 Jul 4, 2021 Apr 4, 2021
Selected Financial Data (US$ in millions)
Short-term borrowings, including current portion of long-term debt 4,303 4,295 4,470 6,946 9,699 11,944 8,232 10,350 2,548 3,985 4,188 2,945 4,040 5,990 645 2,241 3,629 3,888 4,352
Long-term debt, excluding current portion 57,409 57,502 57,639 57,405 58,002 57,506 61,307 61,538 61,048 61,356 31,704 32,884 32,629 34,294 35,656 36,195 36,250 35,354 35,347
Total debt 61,712 61,797 62,109 64,351 67,701 69,450 69,539 71,888 63,596 65,341 35,892 35,829 36,669 40,284 36,301 38,436 39,879 39,242 39,699
Total Pfizer Inc. shareholders’ equity 92,801 88,695 90,338 88,203 92,286 87,700 92,282 89,014 96,934 99,019 100,970 95,661 92,631 87,208 82,424 77,201 75,691 70,042 68,620
Total capital 154,513 150,492 152,447 152,554 159,987 157,150 161,821 160,902 160,530 164,360 136,862 131,490 129,300 127,492 118,725 115,637 115,570 109,284 108,319
Solvency Ratio
Debt to capital1 0.40 0.41 0.41 0.42 0.42 0.44 0.43 0.45 0.40 0.40 0.26 0.27 0.28 0.32 0.31 0.33 0.35 0.36 0.37
Benchmarks
Debt to Capital, Competitors2
AbbVie Inc. 1.04 1.00 0.98 0.95 0.92 0.91 0.90 0.85 0.83 0.83 0.82 0.79 0.81 0.83 0.82 0.83 0.86 0.87 0.86
Amgen Inc. 0.85 0.88 0.90 0.91 0.89 0.91 0.93 0.91 0.89 0.90 0.92 0.91 0.91 0.94 0.98 0.83 0.82 0.80 0.78
Bristol-Myers Squibb Co. 0.73 0.74 0.74 0.75 0.74 0.75 0.77 0.57 0.56 0.54 0.54 0.56 0.54 0.56 0.59 0.55 0.55 0.55 0.55
Danaher Corp. 0.25 0.25 0.24 0.24 0.25 0.25 0.25 0.26 0.30 0.28 0.28 0.28 0.29 0.30 0.32 0.33 0.35 0.32 0.33
Eli Lilly & Co. 0.64 0.69 0.71 0.70 0.69 0.68 0.67 0.70 0.64 0.63 0.63 0.60 0.61 0.66 0.64 0.65 0.69 0.72 0.70
Gilead Sciences Inc. 0.56 0.57 0.58 0.56 0.56 0.59 0.52 0.53 0.54 0.55 0.54 0.54 0.56 0.57 0.56 0.56 0.60 0.61
Johnson & Johnson 0.37 0.39 0.40 0.34 0.34 0.37 0.32 0.30 0.30 0.38 0.43 0.34 0.30 0.30 0.31 0.31 0.33 0.32 0.34
Merck & Co. Inc. 0.44 0.42 0.42 0.44 0.46 0.46 0.46 0.48 0.46 0.49 0.40 0.40 0.41 0.42 0.44 0.46 0.42 0.44 0.54
Regeneron Pharmaceuticals Inc. 0.08 0.08 0.08 0.08 0.08 0.09 0.09 0.09 0.10 0.10 0.10 0.11 0.11 0.12 0.12 0.13 0.14 0.15 0.18
Thermo Fisher Scientific Inc. 0.41 0.41 0.41 0.39 0.42 0.43 0.44 0.43 0.44 0.44 0.45 0.44 0.40 0.42 0.45 0.46 0.36 0.34 0.35
Vertex Pharmaceuticals Inc. 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00

Based on: 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-10-03), 10-Q (reporting date: 2021-07-04), 10-Q (reporting date: 2021-04-04).

1 Q3 2025 Calculation
Debt to capital = Total debt ÷ Total capital
= 61,712 ÷ 154,513 = 0.40

2 Click competitor name to see calculations.


The analysis of the financial leverage metrics reveals specific trends in the company's debt structure and capitalization over the observed periods from early 2021 through mid-2025.

Total Debt
The total debt shows moderate fluctuations across the periods. Initial values around 39 billion US dollars in early 2021 experienced a decline reaching approximately 35.8 billion by the end of 2022. However, starting in the first quarter of 2023, there is a notable increase with debt peaking at about 71.9 billion in the final quarter of 2023. Subsequently, a gradual reduction trend is observed, settling near 61.7 billion by the third quarter of 2025. This pattern indicates a significant spike in borrowings or financial obligations around 2023, followed by a deleveraging phase in the subsequent periods.
Total Capital
Total capital exhibits a generally upward trajectory throughout the timeframe. From about 108.3 billion in early 2021, capital increased steadily to reach a peak exceeding 164 billion in early 2023. After this peak, capital levels stabilized with minor variations, remaining close to the range of 150 to 160 billion through 2024 and mid-2025. The growth in total capital suggests expansion in the company’s financing base, potentially reflecting increased equity, retained earnings, or other capital sources alongside debt.
Debt to Capital Ratio
The debt to capital ratio, representing the proportion of debt relative to total capitalization, declined from 0.37 in early 2021 to a low of around 0.26 by early 2023. This decline aligns with improvements in capital and reductions in debt observed earlier. However, the ratio sharply increased afterward, peaking at 0.45 by the final quarter of 2023, indicating a substantial rise in reliance on debt financing during that period. Post-2023, the debt to capital ratio gradually decreased to approximately 0.40 by mid-2025 but remained higher than pre-2023 levels, signifying the company maintained a relatively higher leverage position compared to earlier periods.

In summary, the data illustrates a period of deleveraging and capital growth until early 2023, followed by an increase in debt and leverage, then a gradual return towards lower debt dependency while maintaining increased total capital. These movements could reflect strategic financing decisions, such as funding acquisitions or investments, and subsequent efforts to re-balance the capital structure.


Debt to Assets

Pfizer Inc., debt to assets calculation (quarterly data)

Microsoft Excel
Sep 28, 2025 Jun 29, 2025 Mar 30, 2025 Dec 31, 2024 Sep 29, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Oct 1, 2023 Jul 2, 2023 Apr 2, 2023 Dec 31, 2022 Oct 2, 2022 Jul 3, 2022 Apr 3, 2022 Dec 31, 2021 Oct 3, 2021 Jul 4, 2021 Apr 4, 2021
Selected Financial Data (US$ in millions)
Short-term borrowings, including current portion of long-term debt 4,303 4,295 4,470 6,946 9,699 11,944 8,232 10,350 2,548 3,985 4,188 2,945 4,040 5,990 645 2,241 3,629 3,888 4,352
Long-term debt, excluding current portion 57,409 57,502 57,639 57,405 58,002 57,506 61,307 61,538 61,048 61,356 31,704 32,884 32,629 34,294 35,656 36,195 36,250 35,354 35,347
Total debt 61,712 61,797 62,109 64,351 67,701 69,450 69,539 71,888 63,596 65,341 35,892 35,829 36,669 40,284 36,301 38,436 39,879 39,242 39,699
 
Total assets 208,731 206,095 208,028 213,396 219,476 216,193 221,095 226,501 215,021 220,168 195,617 197,205 194,350 195,290 183,841 181,476 179,188 169,920 158,818
Solvency Ratio
Debt to assets1 0.30 0.30 0.30 0.30 0.31 0.32 0.31 0.32 0.30 0.30 0.18 0.18 0.19 0.21 0.20 0.21 0.22 0.23 0.25
Benchmarks
Debt to Assets, Competitors2
AbbVie Inc. 0.51 0.51 0.51 0.50 0.50 0.50 0.50 0.44 0.45 0.45 0.46 0.46 0.49 0.51 0.51 0.52 0.54 0.56 0.57
Amgen Inc. 0.61 0.64 0.64 0.65 0.66 0.69 0.69 0.67 0.67 0.68 0.69 0.60 0.61 0.62 0.62 0.54 0.58 0.55 0.52
Bristol-Myers Squibb Co. 0.51 0.52 0.54 0.54 0.53 0.55 0.56 0.42 0.41 0.40 0.40 0.41 0.40 0.42 0.44 0.41 0.40 0.41 0.41
Danaher Corp. 0.21 0.21 0.21 0.21 0.22 0.22 0.22 0.22 0.25 0.23 0.23 0.23 0.24 0.25 0.26 0.27 0.29 0.26 0.27
Eli Lilly & Co. 0.37 0.40 0.43 0.43 0.41 0.40 0.41 0.39 0.35 0.34 0.36 0.33 0.33 0.36 0.35 0.35 0.35 0.35 0.35
Gilead Sciences Inc. 0.45 0.44 0.45 0.43 0.44 0.45 0.40 0.40 0.40 0.41 0.40 0.40 0.42 0.42 0.39 0.41 0.44 0.45
Johnson & Johnson 0.24 0.26 0.27 0.20 0.20 0.23 0.20 0.18 0.18 0.24 0.27 0.21 0.18 0.18 0.19 0.19 0.19 0.19 0.19
Merck & Co. Inc. 0.32 0.30 0.30 0.32 0.32 0.34 0.32 0.33 0.33 0.35 0.29 0.28 0.28 0.30 0.30 0.31 0.28 0.29 0.34
Regeneron Pharmaceuticals Inc. 0.07 0.07 0.07 0.07 0.07 0.07 0.08 0.08 0.08 0.09 0.09 0.09 0.10 0.10 0.10 0.11 0.11 0.13 0.15
Thermo Fisher Scientific Inc. 0.35 0.35 0.35 0.32 0.35 0.36 0.37 0.35 0.36 0.36 0.37 0.35 0.32 0.33 0.36 0.37 0.29 0.28 0.28
Vertex Pharmaceuticals Inc. 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00

Based on: 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-10-03), 10-Q (reporting date: 2021-07-04), 10-Q (reporting date: 2021-04-04).

1 Q3 2025 Calculation
Debt to assets = Total debt ÷ Total assets
= 61,712 ÷ 208,731 = 0.30

2 Click competitor name to see calculations.


Total Debt
The total debt showed a fluctuating pattern over the observed periods. Initially, debt decreased slightly from approximately $39,699 million to $36,301 million between early 2021 and early 2022. Following this, there was a modest rise and stabilization around the $36,000 to $40,000 million range until early 2023. From April 2023 onwards, a marked increase in total debt is evident, peaking at approximately $71,888 million by the end of 2023. After this peak, total debt gradually declined, settling in the range of about $61,712 million by late 2025.
Total Assets
Total assets generally trended upward during the initial period, rising from about $158,818 million in early 2021 to a peak exceeding $226,000 million by late 2023. However, following this peak, a slight downward adjustment occurred, with assets decreasing to approximately $206,730 million by late 2025. Despite the decrease, total assets remained considerably higher than at the beginning of the observed timeframe.
Debt to Assets Ratio
The debt to assets ratio exhibited a declining trend from 0.25 in early 2021 to a low of 0.18 by late 2022, indicating an improvement in leverage position as debt decreased relative to assets. However, starting in early 2023, the ratio increased sharply to reach about 0.32 by the end of 2023, reflecting the surge in debt relative to total assets during this period. Subsequently, the ratio stabilized around 0.30 through to late 2025, suggesting a sustained higher leverage level compared to prior years.
Overall Analysis
The data indicate a period of relative financial stability with modest debt and asset growth through early 2023. The sudden and significant increase in total debt beginning in early 2023 appears to have driven the rise in the debt to assets ratio, coinciding with a peak in total assets. The subsequent gradual reduction in both debt and assets, along with a stabilized leverage ratio around 0.30, suggests a strategic deleveraging or asset revaluation phase. The company’s leverage increased notably in the mid-term period but then moved towards a more balanced state in the later periods, maintaining a debt to assets ratio higher than the earlier years but stable nonetheless.

Financial Leverage

Pfizer Inc., financial leverage calculation (quarterly data)

Microsoft Excel
Sep 28, 2025 Jun 29, 2025 Mar 30, 2025 Dec 31, 2024 Sep 29, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Oct 1, 2023 Jul 2, 2023 Apr 2, 2023 Dec 31, 2022 Oct 2, 2022 Jul 3, 2022 Apr 3, 2022 Dec 31, 2021 Oct 3, 2021 Jul 4, 2021 Apr 4, 2021
Selected Financial Data (US$ in millions)
Total assets 208,731 206,095 208,028 213,396 219,476 216,193 221,095 226,501 215,021 220,168 195,617 197,205 194,350 195,290 183,841 181,476 179,188 169,920 158,818
Total Pfizer Inc. shareholders’ equity 92,801 88,695 90,338 88,203 92,286 87,700 92,282 89,014 96,934 99,019 100,970 95,661 92,631 87,208 82,424 77,201 75,691 70,042 68,620
Solvency Ratio
Financial leverage1 2.25 2.32 2.30 2.42 2.38 2.47 2.40 2.54 2.22 2.22 1.94 2.06 2.10 2.24 2.23 2.35 2.37 2.43 2.31
Benchmarks
Financial Leverage, Competitors2
AbbVie Inc. 95.89 40.65 23.78 20.94 18.59 13.00 11.26 10.52 10.14 8.04 8.84 9.77 8.80 9.51 10.99 11.77 10.98
Amgen Inc. 9.37 11.83 14.40 15.63 12.07 15.34 18.51 15.59 11.83 13.31 16.59 17.79 17.44 24.51 64.62 9.13 7.91 7.25 6.70
Bristol-Myers Squibb Co. 5.22 5.43 5.32 5.67 5.46 5.56 6.01 3.23 3.15 2.92 2.96 3.12 3.01 3.08 3.26 3.04 2.98 3.01 2.99
Danaher Corp. 1.56 1.56 1.56 1.57 1.57 1.57 1.56 1.58 1.67 1.64 1.65 1.68 1.72 1.76 1.80 1.84 1.90 1.82 1.87
Eli Lilly & Co. 4.83 5.52 5.67 5.55 5.31 5.30 4.99 5.94 5.16 4.95 4.75 4.65 4.71 5.51 5.03 5.44 6.21 7.42 6.79
Gilead Sciences Inc. 2.83 2.95 3.05 2.95 2.93 3.21 2.72 2.80 2.95 2.95 2.97 2.97 3.11 3.17 3.23 3.13 3.45 3.56
Johnson & Johnson 2.43 2.46 2.48 2.52 2.54 2.53 2.46 2.44 2.33 2.55 2.77 2.44 2.35 2.33 2.39 2.46 2.55 2.54 2.62
Merck & Co. Inc. 2.50 2.40 2.38 2.53 2.64 2.58 2.62 2.84 2.59 2.70 2.30 2.37 2.41 2.48 2.61 2.77 2.61 2.72 3.37
Regeneron Pharmaceuticals Inc. 1.30 1.28 1.28 1.29 1.28 1.28 1.27 1.27 1.29 1.28 1.28 1.29 1.29 1.32 1.32 1.36 1.37 1.42 1.48
Thermo Fisher Scientific Inc. 2.02 2.00 2.01 1.96 2.05 2.08 2.13 2.11 2.14 2.15 2.24 2.21 2.08 2.14 2.26 2.33 1.90 1.84 1.88
Vertex Pharmaceuticals Inc. 1.44 1.40 1.39 1.37 1.42 1.36 1.29 1.29 1.32 1.32 1.31 1.30 1.28 1.31 1.31 1.33 1.32 1.33 1.35

Based on: 10-Q (reporting date: 2025-09-28), 10-Q (reporting date: 2025-06-29), 10-Q (reporting date: 2025-03-30), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-29), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-10-01), 10-Q (reporting date: 2023-07-02), 10-Q (reporting date: 2023-04-02), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-10-02), 10-Q (reporting date: 2022-07-03), 10-Q (reporting date: 2022-04-03), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-10-03), 10-Q (reporting date: 2021-07-04), 10-Q (reporting date: 2021-04-04).

1 Q3 2025 Calculation
Financial leverage = Total assets ÷ Total Pfizer Inc. shareholders’ equity
= 208,731 ÷ 92,801 = 2.25

2 Click competitor name to see calculations.


The total assets of the company showed a general upward trend from April 2021 through December 2023, increasing from approximately $158.8 billion to around $226.5 billion. However, starting in early 2024, the total assets exhibited some volatility with declines observed through mid-2025, lowering the figure to approximately $208.7 billion by September 2025.

Shareholders’ equity steadily increased from April 2021, growing from about $68.6 billion to peak at nearly $101 billion in April 2023. After this peak, equity declined significantly through December 2023, reaching approximately $89 billion. Starting in early 2024, equity experienced fluctuations but generally remained in the range of $88 billion to $93 billion up to September 2025, showing a less consistent trajectory compared to earlier periods.

The financial leverage ratio generally trended downward from April 2021 to April 2023, falling from 2.31 to 1.94, indicating a relative reduction in reliance on debt financing during this interval. However, from mid-2023 onward, the trend reversed, with leverage increasing and peaking at 2.54 by December 2023. Subsequently, the leverage ratio declined somewhat but remained elevated in comparison with earlier years, fluctuating between 2.25 and 2.47 through mid-2025, suggesting a relative increase in debt use compared to equity in the most recent periods.

Total Assets
Increased steadily between 2021 and 2023, followed by volatility and a downward adjustment from early 2024 to mid-2025.
Shareholders’ Equity
Displayed consistent growth until early 2023, peaked, then experienced notable volatility and relative stabilization at a lower range through 2024 and mid-2025.
Financial Leverage
Decreased through early 2023, indicating lower debt reliance, then increased markedly by the end of 2023, before slightly tapering but remaining elevated through 2025.

Overall, while the asset base expanded over the initial periods, recent trends highlight some contraction and fluctuations in both assets and equity. The leverage fluctuations suggest changes in the company’s capital structure strategy, with a shift back towards greater use of debt financing after a period of deleveraging. These dynamics may warrant close monitoring to assess their impact on financial stability and risk profile going forward.