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- Analysis of Short-term (Operating) Activity Ratios
- Analysis of Long-term (Investment) Activity Ratios
- Enterprise Value (EV)
- Price to FCFE (P/FCFE)
- Selected Financial Data since 2005
- Operating Profit Margin since 2005
- Debt to Equity since 2005
- Total Asset Turnover since 2005
- Price to Earnings (P/E) since 2005
- Analysis of Revenues
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Adjusted Financial Ratios (Summary)
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
An examination of the presented financial ratios reveals several noteworthy trends between 2021 and 2025. Generally, asset utilization and profitability metrics demonstrate a declining trend, while liquidity and leverage ratios exhibit relative stability with some fluctuations. The adjustments applied to these ratios consistently result in slightly more conservative figures compared to the reported values.
- Asset Turnover
- Both the reported and adjusted total asset turnover ratios demonstrate a consistent downward trend over the five-year period, decreasing from 0.63 to 0.35 and 0.65 to 0.39 respectively. This suggests a decreasing efficiency in utilizing assets to generate revenue. The adjusted ratio remains slightly higher than the reported ratio throughout the period.
- Liquidity
- The reported and adjusted current ratios both increased from 2021 to 2023, peaking at 5.69 and 6.57 respectively, indicating strengthening short-term liquidity. However, both ratios then experienced a decline through 2025, settling at 4.73 and 4.72. Despite the recent decrease, both ratios remain above 4.0, suggesting a comfortable liquidity position. The adjusted current ratio consistently exceeds the reported value.
- Leverage
- The reported and adjusted debt-to-equity ratios both show a decreasing trend, moving from 0.14 to 0.09 and 0.15 to 0.11 respectively. This indicates a reduction in the proportion of debt financing relative to equity. A similar pattern is observed in the debt-to-capital ratios, decreasing from 0.13 to 0.08 and 0.13 to 0.10. Financial leverage ratios remain relatively stable, fluctuating between 1.27 and 1.36, with adjusted values mirroring this pattern. These trends suggest a decreasing reliance on financial leverage.
- Profitability
- The reported net profit margin experienced a substantial decline from 50.25% in 2021 to 31.41% in 2025. The adjusted net profit margin exhibits a similar, though more pronounced, decrease, falling from 48.60% to 26.26%. Both return on equity (ROE) and return on assets (ROA) also demonstrate significant declines over the period. ROE decreased from 43.03% to 14.41% (reported) and from 42.12% to 13.43% (adjusted). ROA decreased from 31.75% to 11.11% (reported) and from 31.57% to 10.29% (adjusted). These declines indicate a diminishing ability to generate profits from both equity and assets.
The adjustments made to the ratios generally result in lower values, suggesting that the reported figures may be influenced by factors not fully captured in the core financial statements. The consistent trends observed across both reported and adjusted ratios indicate that these changes are not simply artifacts of accounting adjustments, but rather reflect underlying shifts in the company’s financial performance and position.
Regeneron Pharmaceuticals Inc., Financial Ratios: Reported vs. Adjusted
Adjusted Total Asset Turnover
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
1 2025 Calculation
Total asset turnover = Revenues ÷ Total assets
= ÷ =
2 Adjusted revenues. See details »
3 Adjusted total assets. See details »
4 2025 Calculation
Adjusted total asset turnover = Adjusted revenues ÷ Adjusted total assets
= ÷ =
The adjusted total asset turnover ratio for the period demonstrates a consistent, albeit gradual, decline. Revenues and total assets both increased over the five-year period, but the rate of asset growth exceeded that of revenue growth, contributing to the observed trend.
- Adjusted Total Asset Turnover Trend
- The adjusted total asset turnover ratio began at 0.65 in 2021. It increased slightly to 0.44 in 2022, then remained relatively stable at 0.43 in 2023, before decreasing to 0.42 in 2024 and further to 0.39 in 2025. This indicates a decreasing efficiency in generating revenue from its asset base.
- Revenue Analysis
- Adjusted revenues experienced a decrease from US$15,951,500 thousand in 2021 to US$12,205,300 thousand in 2022. Following this decline, revenues showed a pattern of growth, reaching US$14,429,800 thousand in 2024, before settling at US$14,291,200 thousand in 2025. The growth rate appears to be slowing in the most recent year.
- Asset Analysis
- Adjusted total assets exhibited a consistent upward trend throughout the period. Starting at US$24,557,900 thousand in 2021, assets grew to US$27,490,800 thousand in 2022, US$30,504,800 thousand in 2023, US$34,445,300 thousand in 2024, and ultimately reached US$36,481,500 thousand in 2025. The rate of asset increase was notably higher than the revenue growth rate, particularly between 2021 and 2024.
The consistent increase in assets coupled with a relatively stable revenue base, and a slight decline in the most recent year, suggests the company is investing in assets that are not yet translating into proportional revenue gains. Further investigation into the composition of these assets and the reasons for the revenue stabilization may be warranted.
Adjusted Current Ratio
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
1 2025 Calculation
Current ratio = Current assets ÷ Current liabilities
= ÷ =
2 Adjusted current liabilities. See details »
3 2025 Calculation
Adjusted current ratio = Current assets ÷ Adjusted current liabilities
= ÷ =
The reported current ratio demonstrates fluctuation over the five-year period. Initially increasing from 3.56 in 2021 to a peak of 5.69 in 2023, it subsequently declined to 4.13 by 2025. The adjusted current ratio, which utilizes adjusted current liabilities, exhibits a similar pattern but consistently reports higher values than the reported current ratio. This suggests the adjustments to current liabilities have a notable impact on the assessment of short-term liquidity.
- Current Assets
- Current assets increased from US$14,014,900 thousand in 2021 to US$19,479,200 thousand in 2023, representing substantial growth. However, a slight decrease is observed in 2024 and 2025, settling at US$18,021,900 thousand. This indicates a potential stabilization or modest contraction of short-term assets in the latter part of the period.
- Current Liabilities
- Current liabilities decreased from US$3,932,500 thousand in 2021 to US$3,141,300 thousand in 2022, before increasing again to US$3,944,300 thousand in 2024. A further increase is noted in 2025, reaching US$4,368,400 thousand. This suggests a fluctuating short-term obligation profile.
- Reported Current Ratio Trend
- The reported current ratio increased significantly between 2021 and 2023, indicating improving short-term liquidity. The subsequent decline in 2024 and 2025 suggests a potential weakening of this position, although the ratio remains above 4.0 throughout the period.
- Adjusted Current Ratio Trend
- The adjusted current ratio mirrors the trend of the reported current ratio, with increases from 4.02 in 2021 to 6.57 in 2023, followed by declines to 4.72 in 2025. The consistently higher values compared to the reported current ratio indicate that the adjustments made to current liabilities result in a more favorable liquidity assessment. The adjustments appear to reduce the reported short-term obligations, thereby improving the ratio.
- Adjusted Liabilities Impact
- The difference between reported and adjusted current liabilities narrows over time. In 2021, adjusted current liabilities were approximately 11% lower than reported liabilities. By 2025, this difference had decreased to approximately 6%. This suggests a diminishing effect from the adjustments made to current liabilities, potentially indicating a change in the nature of those obligations.
Adjusted Debt to Equity
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
1 2025 Calculation
Debt to equity = Total debt ÷ Stockholders’ equity
= ÷ =
2 Adjusted total debt. See details »
3 Adjusted stockholders’ equity. See details »
4 2025 Calculation
Adjusted debt to equity = Adjusted total debt ÷ Adjusted stockholders’ equity
= ÷ =
The financial information presents a five-year trend of debt and equity figures, culminating in adjusted debt-to-equity ratios. Total debt exhibits a modest, consistent increase annually, moving from US$2,699,700 thousand in 2021 to US$2,705,900 thousand in 2025. Stockholders’ equity demonstrates a more substantial and accelerating growth pattern over the same period, rising from US$18,768,800 thousand to US$31,256,900 thousand. Consequently, the reported debt-to-equity ratio shows a declining trend, decreasing from 0.14 in 2021 to 0.09 in both 2024 and 2025.
- Adjusted Debt-to-Equity Ratio Trend
- The adjusted debt-to-equity ratio presents a slightly different pattern than the reported ratio. It begins at 0.15 in 2021, decreases to 0.13 in 2022, and then holds steady at 0.12 in 2023 before declining to 0.11 in both 2024 and 2025. This suggests that the adjustments made to total debt and stockholders’ equity have a stabilizing effect on the ratio in the later years of the observed period.
Adjusted total debt also shows a consistent, albeit smaller, increase annually, from US$2,767,900 thousand in 2021 to US$2,972,700 thousand in 2025. Adjusted stockholders’ equity mirrors the trend of total stockholders’ equity, with consistent growth from US$18,407,200 thousand in 2021 to US$27,941,400 thousand in 2025. The rate of increase in adjusted stockholders’ equity appears to decelerate slightly between 2023 and 2025.
- Debt and Equity Growth
- While both debt and equity increase over the five-year period, the growth in equity significantly outpaces the growth in debt. This disparity is the primary driver of the declining trend in both the reported and adjusted debt-to-equity ratios. The consistent increases in debt, even if modest, should be monitored to ensure they remain aligned with the company’s strategic objectives and capacity for repayment.
- Impact of Adjustments
- The adjustments to total debt and stockholders’ equity result in a slightly higher debt-to-equity ratio compared to the reported figures. This indicates that the adjustments likely involve recognizing additional liabilities or reducing reported equity components. The nature of these adjustments would require further investigation to fully understand their impact on the company’s financial position.
Overall, the financial position appears to be strengthening, as evidenced by the declining debt-to-equity ratios. The consistent growth in equity provides a buffer against the modest increase in debt. Continued monitoring of these trends, along with a detailed understanding of the adjustments made to debt and equity, is recommended.
Adjusted Debt to Capital
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
1 2025 Calculation
Debt to capital = Total debt ÷ Total capital
= ÷ =
2 Adjusted total debt. See details »
3 Adjusted total capital. See details »
4 2025 Calculation
Adjusted debt to capital = Adjusted total debt ÷ Adjusted total capital
= ÷ =
The information presents a five-year trend of debt and capital figures, culminating in the calculation of both reported and adjusted debt-to-capital ratios. Total debt exhibits a modest, consistent increase annually, moving from US$2,699,700 thousand in 2021 to US$2,705,900 thousand in 2025. Total capital demonstrates a more substantial and accelerating growth pattern, rising from US$21,468,500 thousand in 2021 to US$33,962,800 thousand in 2025.
- Reported Debt to Capital
- The reported debt-to-capital ratio shows a consistent decline over the five-year period. Starting at 0.13 in 2021, it decreases to 0.08 by 2024 and remains stable at that level through 2025. This indicates a decreasing reliance on debt financing relative to the company’s capital base.
- Adjusted Debt to Capital
- The adjusted debt-to-capital ratio also demonstrates a decreasing trend, though less pronounced than the reported ratio. It begins at 0.13 in 2021, falling to 0.10 in 2023 and holding steady at 0.10 through 2025. The adjusted figures suggest a similar pattern of reduced debt leverage when considering the adjustments made to the total debt and total capital calculations.
The difference between the reported and adjusted ratios is minimal throughout the period, suggesting that the adjustments applied to total debt and total capital have a limited impact on the overall leverage picture. The consistent growth in total capital, exceeding the growth in total debt, is the primary driver of the observed declining trends in both the reported and adjusted debt-to-capital ratios. This suggests the company is increasingly funding its operations and growth through equity or retained earnings rather than debt.
- Debt and Capital Growth
- While total debt increases incrementally, the rate of increase is significantly lower than that of total capital. This disparity contributes to the declining debt-to-capital ratios. The acceleration in capital growth, particularly between 2023 and 2025, further reinforces this trend.
The stability of both ratios at 0.08 and 0.10 respectively in the later years of the period indicates a potential stabilization of the company’s capital structure and debt leverage.
Adjusted Financial Leverage
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
1 2025 Calculation
Financial leverage = Total assets ÷ Stockholders’ equity
= ÷ =
2 Adjusted total assets. See details »
3 Adjusted stockholders’ equity. See details »
4 2025 Calculation
Adjusted financial leverage = Adjusted total assets ÷ Adjusted stockholders’ equity
= ÷ =
An examination of the financial information reveals trends in both reported and adjusted financial leverage over a five-year period. Total assets and stockholders’ equity consistently increased annually, contributing to changes in leverage ratios. The adjusted figures demonstrate a slightly different picture than the reported values, though the overall trends are similar.
- Total Assets & Stockholders’ Equity
- Total assets increased steadily from US$25.43 billion in 2021 to US$40.56 billion in 2025, representing a compound annual growth rate of approximately 9.8%. Stockholders’ equity also exhibited consistent growth, rising from US$18.77 billion in 2021 to US$31.26 billion in 2025, a compound annual growth rate of roughly 9.3%.
- Reported Financial Leverage
- Reported financial leverage initially decreased from 1.36 in 2021 to 1.27 in 2022, then remained relatively stable at 1.27 in 2023. A slight increase to 1.29 was observed in 2024, followed by a further increase to 1.30 in 2025. This indicates a modest increase in leverage towards the end of the period.
- Adjusted Financial Leverage
- Adjusted financial leverage mirrored the trend of the reported ratio, decreasing from 1.33 in 2021 to 1.27 in 2022. It remained at 1.27 in 2023, increased to 1.28 in 2024, and then rose to 1.31 in 2025. The adjusted leverage ratio consistently remained slightly below the reported leverage ratio throughout the period. The increase in 2025 represents the highest leverage observed in the five-year period, although the difference is minimal.
- Adjustments Impact
- The adjustments to total assets and stockholders’ equity resulted in lower leverage ratios compared to the reported figures. The magnitude of the adjustment remained relatively consistent across the years, suggesting a systematic difference in accounting or valuation methods. The adjustments appear to reduce the reported financial risk, as indicated by the lower leverage ratios.
In summary, the company demonstrated increasing asset and equity bases alongside relatively stable, and slightly increasing, financial leverage. The adjustments applied to the financial items resulted in consistently lower leverage ratios, indicating a potentially more conservative financial position when considering these adjustments.
Adjusted Net Profit Margin
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
1 2025 Calculation
Net profit margin = 100 × Net income ÷ Revenues
= 100 × ÷ =
2 Adjusted net income. See details »
3 Adjusted revenues. See details »
4 2025 Calculation
Adjusted net profit margin = 100 × Adjusted net income ÷ Adjusted revenues
= 100 × ÷ =
The adjusted net profit margin exhibited a declining trend from 2021 to 2023, followed by a period of stabilization and slight fluctuation through 2025. Initial values were relatively high, but experienced significant decreases before leveling off. A comparison with reported net profit margin reveals that adjustments consistently result in lower profitability figures.
- Adjusted Net Profit Margin - Overall Trend
- The adjusted net profit margin decreased from 48.60% in 2021 to 25.17% in 2023, representing a substantial decline. This was followed by a recovery to 27.42% in 2024 and a slight decrease to 26.26% in 2025. The 2023 value represents the lowest point in the observed period.
- Relationship to Adjusted Revenues
- Adjusted revenues generally increased over the period, moving from US$15,951,500 thousand in 2021 to US$14,291,200 thousand in 2025. However, the increase in revenue did not fully offset the impact of adjustments to net income, contributing to the initial decline in the adjusted net profit margin. The revenue increase from 2023 to 2025 appears to have partially mitigated further declines in the margin.
- Comparison with Reported Net Profit Margin
- The reported net profit margin consistently exceeded the adjusted net profit margin across all years. The difference between the two margins varied, but generally remained between approximately 2.0% and 5.0%. This indicates that adjustments to net income and/or revenues have a material downward impact on reported profitability. The reported margin also showed a similar trend, declining from 50.25% in 2021 to 30.14% in 2023, then recovering to 31.41% in 2025.
- Year-over-Year Changes
- The largest year-over-year decrease in adjusted net profit margin occurred between 2021 and 2022, with a decline of 20.65 percentage points. A further decrease of 7.78 percentage points was observed between 2022 and 2023. The subsequent increase from 2023 to 2024 was 2.25 percentage points, and the decrease from 2024 to 2025 was 1.16 percentage points. These changes suggest that 2022 and 2023 were periods of significant adjustment impacting profitability.
In summary, the adjusted net profit margin experienced a notable decrease in the early part of the period, followed by a period of relative stability. The consistent difference between reported and adjusted margins highlights the importance of understanding the nature of the adjustments being made to assess underlying profitability.
Adjusted Return on Equity (ROE)
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
1 2025 Calculation
ROE = 100 × Net income ÷ Stockholders’ equity
= 100 × ÷ =
2 Adjusted net income. See details »
3 Adjusted stockholders’ equity. See details »
4 2025 Calculation
Adjusted ROE = 100 × Adjusted net income ÷ Adjusted stockholders’ equity
= 100 × ÷ =
The reported return on equity (ROE) exhibited a substantial decline from 43.03% in 2021 to 14.41% in 2025. This decrease is not fully mirrored in the adjusted ROE, which also declined but to a lesser extent, moving from 42.12% to 13.43% over the same period. A comparison of the reported and adjusted figures reveals that adjustments consistently lower the calculated ROE, suggesting the presence of items impacting net income or equity that are excluded in the adjusted calculation.
- Adjusted Return on Equity (ROE) Trend
- The adjusted ROE experienced a significant decrease from 42.12% in 2021 to 15.88% in 2022, representing the largest single-year decline in the observed period. Subsequent years show more moderate decreases, with values of 13.81% in 2023, 14.73% in 2024, and 13.43% in 2025. While fluctuations occur, the overall trend indicates a consistent, albeit decelerating, reduction in adjusted profitability relative to equity.
- Net Income and Equity Relationship
- Both adjusted net income and adjusted stockholders’ equity generally increased from 2021 to 2025. However, the growth in equity outpaced the growth in net income. Adjusted net income increased from US$7,752,500 to US$3,753,200, while adjusted stockholders’ equity rose from US$18,407,200 to US$27,941,400. This disparity contributes to the observed decline in adjusted ROE, as the denominator (equity) is growing at a faster rate than the numerator (net income).
The difference between reported and adjusted ROE suggests that certain accounting treatments or non-recurring items are impacting the reported figures. Further investigation into the nature of these adjustments would be necessary to fully understand their impact on the company’s underlying performance. The stabilization of adjusted ROE between 2024 and 2025, despite continued equity growth, may indicate a leveling off of profitability or a change in the composition of equity.
Adjusted Return on Assets (ROA)
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31).
1 2025 Calculation
ROA = 100 × Net income ÷ Total assets
= 100 × ÷ =
2 Adjusted net income. See details »
3 Adjusted total assets. See details »
4 2025 Calculation
Adjusted ROA = 100 × Adjusted net income ÷ Adjusted total assets
= 100 × ÷ =
The reported Return on Assets (ROA) exhibited a declining trend over the five-year period, starting at 31.75% in 2021 and decreasing to 11.11% in 2025. However, the Adjusted ROA, while also decreasing overall, demonstrated a slightly different pattern. A detailed examination of the Adjusted ROA and its components reveals further insights into the company’s performance.
- Adjusted Return on Assets (ROA) Trend
- The Adjusted ROA began at 31.57% in 2021, decreased to 12.41% in 2022, and continued to decline to 10.86% in 2023. A slight increase was observed in 2024, with the Adjusted ROA reaching 11.49%, before decreasing again to 10.29% in 2025. This suggests some volatility in profitability relative to adjusted assets.
- Net Income Impact
- Adjusted net income generally followed a downward trajectory from 2021 to 2023, decreasing from US$7,752,500 to US$3,311,600. A recovery was seen in 2024, with adjusted net income rising to US$3,956,100, but this growth was not sustained, with a decrease to US$3,753,200 in 2025. The fluctuations in adjusted net income directly influenced the Adjusted ROA.
- Asset Base Changes
- Adjusted total assets consistently increased throughout the period, rising from US$24,557,900 in 2021 to US$36,481,500 in 2025. This continuous growth in the asset base, coupled with the fluctuations in adjusted net income, contributed to the observed trends in Adjusted ROA. The increasing asset base likely diluted the impact of net income on the ROA calculation.
- Comparison to Reported ROA
- The Adjusted ROA values were consistently lower than the Reported ROA values for each year. This indicates that the adjustments made to net income and total assets resulted in a lower calculation of profitability relative to assets. The difference between the Reported and Adjusted ROA suggests that certain accounting treatments or non-recurring items were impacting the initially reported figures.
In summary, while both the Reported and Adjusted ROA experienced a decline over the period, the Adjusted ROA provides a potentially more conservative view of the company’s profitability. The growth in adjusted assets, combined with the volatility in adjusted net income, played a significant role in shaping the Adjusted ROA trend.