Operating Profit Margin
since 2005
Calculation
Regeneron Pharmaceuticals Inc., operating profit margin, long-term trends, calculation
| Operating profit margin | = | 100 | × | Income (loss) from operations1 | ÷ | Revenues1 | |
|---|---|---|---|---|---|---|---|
| Dec 31, 2025 | 24.95% | = | 100 | × | 3,577,900) | ÷ | 14,342,900) |
| Dec 31, 2024 | 28.10% | = | 100 | × | 3,990,700) | ÷ | 14,202,000) |
| Dec 31, 2023 | 30.85% | = | 100 | × | 4,047,100) | ÷ | 13,117,200) |
| Dec 31, 2022 | 38.93% | = | 100 | × | 4,738,900) | ÷ | 12,172,900) |
| Dec 31, 2021 | 55.67% | = | 100 | × | 8,946,800) | ÷ | 16,071,700) |
| Dec 31, 2020 | 42.09% | = | 100 | × | 3,576,600) | ÷ | 8,497,100) |
| Dec 31, 2019 | 28.10% | = | 100 | × | 2,209,800) | ÷ | 7,863,400) |
| Dec 31, 2018 | 37.77% | = | 100 | × | 2,534,400) | ÷ | 6,710,800) |
| Dec 31, 2017 | 35.41% | = | 100 | × | 2,079,591) | ÷ | 5,872,227) |
| Dec 31, 2016 | 27.38% | = | 100 | × | 1,330,741) | ÷ | 4,860,427) |
| Dec 31, 2015 | 30.51% | = | 100 | × | 1,251,916) | ÷ | 4,103,728) |
| Dec 31, 2014 | 29.74% | = | 100 | × | 838,431) | ÷ | 2,819,557) |
| Dec 31, 2013 | 36.11% | = | 100 | × | 760,028) | ÷ | 2,104,745) |
| Dec 31, 2012 | 33.20% | = | 100 | × | 457,713) | ÷ | 1,378,477) |
| Dec 31, 2011 | -46.02% | = | 100 | × | (205,159) | ÷ | 445,824) |
| Dec 31, 2010 | -21.23% | = | 100 | × | (97,472) | ÷ | 459,074) |
| Dec 31, 2009 | -19.54% | = | 100 | × | (74,103) | ÷ | 379,268) |
| Dec 31, 2008 | -37.67% | = | 100 | × | (89,830) | ÷ | 238,457) |
| Dec 31, 2007 | -91.55% | = | 100 | × | (114,454) | ÷ | 125,024) |
| Dec 31, 2006 | -169.68% | = | 100 | × | (107,655) | ÷ | 63,447) |
| Dec 31, 2005 | -187.97% | = | 100 | × | (124,421) | ÷ | 66,193) |
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31), 10-K (reporting date: 2016-12-31), 10-K (reporting date: 2015-12-31), 10-K (reporting date: 2014-12-31), 10-K (reporting date: 2013-12-31), 10-K (reporting date: 2012-12-31), 10-K (reporting date: 2011-12-31), 10-K (reporting date: 2010-12-31), 10-K (reporting date: 2009-12-31), 10-K (reporting date: 2008-12-31), 10-K (reporting date: 2007-12-31), 10-K (reporting date: 2006-12-31), 10-K (reporting date: 2005-12-31).
1 US$ in thousands
The operating profit margin exhibited significant volatility between 2005 and 2025. Initially, the metric was substantially negative, indicating considerable operational losses. Over time, a clear progression towards profitability is observed, followed by periods of fluctuation.
- Early Years (2005-2011)
- From 2005 to 2011, the operating profit margin remained consistently negative. The magnitude of the losses decreased from -187.97% in 2005 to -46.02% in 2011, suggesting a gradual reduction in operational inefficiencies or increasing revenue relative to operating expenses. However, profitability was not yet achieved during this period.
- Transition to Profitability (2012-2018)
- A pivotal shift occurred in 2012, with the operating profit margin turning positive at 33.20%. This positive trend continued, with the margin increasing to 37.77% by 2018. This period demonstrates successful operational improvements and revenue growth exceeding operating costs. The highest margin within this timeframe was recorded in 2017 at 35.41% and 2018 at 37.77%.
- Recent Fluctuations (2019-2025)
- Following the peak in 2018, the operating profit margin experienced fluctuations. It decreased to 28.10% in 2019, then surged to 42.09% in 2020, followed by a decline to 30.85% in 2022 and 28.10% in 2023. The most recent year, 2025, shows a further decrease to 24.95%. This suggests increased cost pressures or a slowdown in revenue growth in recent years, despite generally high revenue figures.
- Overall Trend
- Despite the recent fluctuations, the overall trend indicates a substantial improvement in operational profitability over the two-decade period. The company transitioned from significant operational losses to consistent profitability, although maintaining a stable margin has proven challenging in the later years of the observed period. The substantial increase in revenue between 2020 and 2021 did not translate into a sustained increase in operating profit margin, indicating potential issues with cost control or shifts in product mix.
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Comparison to Competitors
Regeneron Pharmaceuticals Inc., operating profit margin, long-term trends, comparison to competitors
| Regeneron Pharmaceuticals Inc. | AbbVie Inc. | Amgen Inc. | Danaher Corp. | Gilead Sciences Inc. | Thermo Fisher Scientific Inc. | Vertex Pharmaceuticals Inc. | |
|---|---|---|---|---|---|---|---|
| Dec 31, 2025 | 24.95% | 24.65% | 25.83% | 19.09% | 34.66% | 17.38% | 34.77% |
| Dec 31, 2024 | 28.10% | 16.22% | 22.66% | 20.37% | 5.81% | 17.11% | -2.11% |
| Dec 31, 2023 | 30.85% | 23.49% | 29.35% | 21.77% | 28.24% | 16.00% | 38.83% |
| Dec 31, 2022 | 38.93% | 31.21% | 38.57% | 27.61% | 27.17% | 18.69% | 48.23% |
| Dec 31, 2021 | 55.67% | 31.89% | 31.44% | 25.35% | 36.72% | 25.57% | 36.73% |
| Dec 31, 2020 | 42.09% | 24.81% | 37.70% | 18.99% | 16.72% | 24.19% | 46.03% |
| Dec 31, 2019 | 28.10% | 39.03% | 43.57% | 18.25% | 19.38% | 17.99% | 28.77% |
| Dec 31, 2018 | 37.77% | 19.49% | 45.55% | 17.11% | 37.83% | 15.53% | 20.84% |
| Dec 31, 2017 | 35.41% | 33.99% | 45.76% | 16.48% | 55.04% | 14.19% | 4.95% |
| Dec 31, 2016 | 27.38% | 36.60% | 44.74% | 16.29% | 58.87% | 13.40% | 0.58% |
| Dec 31, 2015 | 30.51% | 32.97% | 40.44% | 16.87% | 69.03% | 13.77% | -45.23% |
| Dec 31, 2014 | 29.74% | 17.09% | 32.03% | 17.23% | 62.37% | 14.82% | -119.30% |
| Dec 31, 2013 | 36.11% | 30.14% | 32.25% | 17.13% | 41.87% | 12.30% | -74.54% |
| Dec 31, 2012 | 33.20% | 31.65% | 33.52% | 17.33% | 42.67% | 11.85% | 0.15% |
| Dec 31, 2011 | -46.02% | — | 28.19% | 16.27% | 46.77% | 10.62% | 8.07% |
| Dec 31, 2010 | -21.23% | — | 37.82% | 16.41% | 53.62% | 11.72% | -485.51% |
| Dec 31, 2009 | -19.54% | — | 38.37% | 13.79% | 54.55% | 10.38% | -602.63% |
| Dec 31, 2008 | -37.67% | — | 35.50% | 14.72% | 52.68% | 11.71% | -263.65% |
| Dec 31, 2007 | -91.55% | — | 27.81% | 15.79% | 57.98% | 10.00% | -210.94% |
| Dec 31, 2006 | -169.68% | — | 27.71% | 15.82% | -29.32% | 6.38% | -105.86% |
| Dec 31, 2005 | -187.97% | — | 40.33% | 15.84% | 61.41% | 10.01% | -93.15% |
Based on: 10-K (reporting date: 2025-12-31), 10-K (reporting date: 2024-12-31), 10-K (reporting date: 2023-12-31), 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31), 10-K (reporting date: 2016-12-31), 10-K (reporting date: 2015-12-31), 10-K (reporting date: 2014-12-31), 10-K (reporting date: 2013-12-31), 10-K (reporting date: 2012-12-31), 10-K (reporting date: 2011-12-31), 10-K (reporting date: 2010-12-31), 10-K (reporting date: 2009-12-31), 10-K (reporting date: 2008-12-31), 10-K (reporting date: 2007-12-31), 10-K (reporting date: 2006-12-31), 10-K (reporting date: 2005-12-31).