Stock Analysis on Net

Vertex Pharmaceuticals Inc. (NASDAQ:VRTX)

Analysis of Liquidity Ratios 
Quarterly Data

Microsoft Excel

Liquidity Ratios (Summary)

Vertex Pharmaceuticals Inc., liquidity ratios (quarterly data)

Microsoft Excel
Dec 31, 2025 Sep 30, 2025 Jun 30, 2025 Mar 31, 2025 Dec 31, 2024 Sep 30, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022
Current ratio 2.90 2.36 2.52 2.65 2.69 2.47 2.52 3.50 3.99 4.08 4.14 4.28 4.83 4.70 4.50 4.75
Quick ratio 2.24 1.84 2.00 2.12 2.17 2.08 2.10 3.15 3.60 3.74 3.82 3.95 4.46 4.28 4.14 4.37
Cash ratio 1.71 1.40 1.54 1.64 1.72 1.64 1.63 2.68 3.16 3.31 3.35 3.44 3.93 3.74 3.62 3.78

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).


Over the observed period, the liquidity ratios exhibited distinct trends. Initially, the ratios demonstrated relative stability before experiencing a noticeable decline, followed by some stabilization and a final increase in the most recent period. This suggests a shift in the company’s short-term asset management and liquidity position.

Current Ratio
The current ratio began at 4.75 and remained relatively high through the end of 2022, fluctuating between 4.50 and 4.83. A downward trend commenced in early 2023, decreasing to 3.99 by December 2023. This decline continued into the first half of 2024, reaching a low of 2.52 in June. A slight recovery was observed in the latter half of 2024, increasing to 2.69 by December, and continued into 2025, reaching 2.90 by December. This indicates a weakening, then stabilization, and finally a modest improvement in the company’s ability to cover its current liabilities with current assets.
Quick Ratio
Similar to the current ratio, the quick ratio showed initial stability, ranging from 4.14 to 4.46 between March 2022 and December 2022. A consistent decline was then observed, falling from 3.95 in March 2023 to 2.08 in June 2024. The ratio experienced a slight increase to 2.17 by December 2024, but continued to decrease to 1.84 in September 2025 before recovering to 2.24 by December 2025. This pattern suggests a decreasing ability to meet short-term obligations with the most liquid assets, excluding inventory.
Cash Ratio
The cash ratio followed a comparable trajectory. Starting at 3.78, it remained relatively stable through December 2022. A gradual decline began in 2023, reaching 3.16 by December. This downward trend continued into 2024, with the ratio falling to a low of 1.63 in June. A modest recovery was seen in the latter half of 2024 and into 2025, culminating in a ratio of 1.71 by December 2025. This indicates a diminishing capacity to cover immediate liabilities with cash and cash equivalents, followed by a slight improvement.

The consistent declines in all three ratios throughout 2023 and the first half of 2024 suggest a potential shift in working capital management or increased short-term obligations. The subsequent stabilization and modest increases in the most recent periods indicate a possible reversal of this trend, though the ratios remain lower than their initial levels. Further investigation into the underlying factors driving these changes would be beneficial.


Current Ratio

Vertex Pharmaceuticals Inc., current ratio calculation (quarterly data)

Microsoft Excel
Dec 31, 2025 Sep 30, 2025 Jun 30, 2025 Mar 31, 2025 Dec 31, 2024 Sep 30, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022
Selected Financial Data (US$ in thousands)
Current assets 11,201,000 10,569,600 10,427,900 10,008,800 9,596,400 9,804,100 8,941,600 13,288,700 14,144,200 14,695,800 13,872,900 12,965,700 13,234,800 12,271,000 11,503,500 10,361,300
Current liabilities 3,861,200 4,475,300 4,138,400 3,783,200 3,564,600 3,973,100 3,547,200 3,795,900 3,547,400 3,599,400 3,352,100 3,026,200 2,742,100 2,609,300 2,556,200 2,180,200
Liquidity Ratio
Current ratio1 2.90 2.36 2.52 2.65 2.69 2.47 2.52 3.50 3.99 4.08 4.14 4.28 4.83 4.70 4.50 4.75
Benchmarks
Current Ratio, Competitors2
AbbVie Inc. 0.67 0.72 0.74 0.76 0.66 0.65 0.81 0.94 0.87 0.96 0.89 0.96 0.96 0.93 0.84 0.82
Amgen Inc. 1.14 1.28 1.31 1.17 1.26 1.32 1.26 1.42 1.65 2.86 2.77 3.14 1.41 1.68 1.53 1.44
Bristol-Myers Squibb Co. 1.26 1.27 1.21 1.28 1.25 1.24 1.16 1.11 1.43 1.18 1.39 1.42 1.25 1.42 1.44 1.32
Danaher Corp. 1.87 1.52 1.62 1.43 1.40 1.37 1.43 1.85 1.68 2.26 2.08 1.89 1.89 1.78 1.75 1.68
Eli Lilly & Co. 1.58 1.55 1.28 1.37 1.15 1.27 1.11 1.35 0.94 1.05 1.13 1.30 1.05 1.13 1.10 1.27
Gilead Sciences Inc. 1.55 1.45 1.32 1.37 1.60 1.26 1.14 1.08 1.43 1.34 1.02 1.28 1.29 1.30 1.43 1.48
Johnson & Johnson 1.03 1.07 1.01 1.26 1.11 1.03 1.07 1.17 1.16 1.21 1.12 1.07 0.99 1.43 1.42 1.39
Merck & Co. Inc. 1.54 1.66 1.42 1.41 1.36 1.36 1.47 1.25 1.25 1.38 1.28 1.44 1.47 1.46 1.39 1.40
Pfizer Inc. 1.16 1.28 1.16 1.26 1.17 1.00 0.86 1.05 0.91 2.38 2.12 1.37 1.22 1.59 1.42 1.39
Regeneron Pharmaceuticals Inc. 4.13 4.06 4.60 4.93 4.73 5.28 5.44 5.27 5.69 5.18 5.45 5.45 5.06 5.36 5.12 4.76
Thermo Fisher Scientific Inc. 1.89 1.50 1.93 1.77 1.66 1.63 1.72 1.70 1.75 1.63 1.42 1.27 1.48 1.74 1.65 1.56

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).

1 Q4 2025 Calculation
Current ratio = Current assets ÷ Current liabilities
= 11,201,000 ÷ 3,861,200 = 2.90

2 Click competitor name to see calculations.


The current ratio exhibited a generally decreasing trend over the observed period, spanning from March 31, 2022, to December 31, 2025. Initially, the ratio demonstrated relative stability in the range of 4.50 to 4.83 between March 2022 and December 2022. However, a consistent decline became apparent starting in the first quarter of 2023, continuing through the first three quarters of 2025.

Initial Period (Mar 31, 2022 – Dec 31, 2022)
The current ratio fluctuated between 4.50 and 4.83, indicating a strong ability to cover short-term liabilities with short-term assets. This suggests a comfortable liquidity position during this timeframe.
Declining Trend (Mar 31, 2023 – Sep 30, 2025)
From March 2023, the current ratio experienced a noticeable decrease, falling from 4.28 to a low of 2.36 in September 2025. This suggests a weakening liquidity position, with a reduced capacity to meet short-term obligations using current assets. The rate of decline appeared to accelerate in the latter half of 2024 and the first three quarters of 2025.
Recent Recovery (Dec 31, 2025)
The ratio showed a slight recovery in December 2025, increasing to 2.90. While this represents an improvement from the September 2025 low, the ratio remains significantly lower than levels observed earlier in the period.
Underlying Components
The decline in the current ratio appears to be driven by a combination of factors. While current assets generally increased between March 2022 and September 2024, the growth rate of current liabilities exceeded that of current assets, particularly from March 2023 onwards. A substantial decrease in current assets was observed between September 2024 and June 2025, contributing to the lowest ratio value in September 2025. The subsequent increase in current assets in December 2025 partially offset this effect.

Overall, the observed trend indicates a progressive deterioration in the company’s short-term liquidity position. The recent slight recovery in the final quarter of 2025 may warrant further investigation to determine its sustainability and underlying causes.


Quick Ratio

Vertex Pharmaceuticals Inc., quick ratio calculation (quarterly data)

Microsoft Excel
Dec 31, 2025 Sep 30, 2025 Jun 30, 2025 Mar 31, 2025 Dec 31, 2024 Sep 30, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022
Selected Financial Data (US$ in thousands)
Cash and cash equivalents 5,084,800 4,939,600 4,972,200 4,674,700 4,569,600 5,239,200 4,580,100 9,158,000 10,369,100 11,110,200 10,151,100 9,289,900 10,504,000 9,171,500 8,702,200 7,600,100
Marketable securities 1,523,300 1,347,400 1,410,600 1,526,500 1,546,300 1,285,300 1,215,400 1,013,300 849,200 818,000 1,085,200 1,124,200 274,500 599,200 551,200 638,000
Accounts receivable, net 2,052,800 1,946,400 1,893,500 1,805,100 1,609,400 1,750,600 1,656,100 1,793,200 1,563,400 1,538,700 1,556,200 1,547,800 1,442,200 1,385,200 1,332,900 1,292,800
Total quick assets 8,660,900 8,233,400 8,276,300 8,006,300 7,725,300 8,275,100 7,451,600 11,964,500 12,781,700 13,466,900 12,792,500 11,961,900 12,220,700 11,155,900 10,586,300 9,530,900
 
Current liabilities 3,861,200 4,475,300 4,138,400 3,783,200 3,564,600 3,973,100 3,547,200 3,795,900 3,547,400 3,599,400 3,352,100 3,026,200 2,742,100 2,609,300 2,556,200 2,180,200
Liquidity Ratio
Quick ratio1 2.24 1.84 2.00 2.12 2.17 2.08 2.10 3.15 3.60 3.74 3.82 3.95 4.46 4.28 4.14 4.37
Benchmarks
Quick Ratio, Competitors2
AbbVie Inc. 0.41 0.47 0.48 0.48 0.43 0.44 0.59 0.72 0.63 0.71 0.63 0.66 0.69 0.69 0.61 0.56
Amgen Inc. 0.73 0.82 0.82 0.74 0.81 0.80 0.75 0.84 0.99 2.41 2.34 2.62 0.95 1.17 0.99 0.90
Bristol-Myers Squibb Co. 0.94 0.99 0.91 0.94 0.91 0.84 0.78 0.78 1.04 0.77 0.94 1.01 0.87 0.98 1.07 1.03
Danaher Corp. 1.25 0.84 0.96 0.83 0.83 0.84 0.85 1.34 1.18 1.76 1.52 1.34 1.30 1.19 1.13 1.08
Eli Lilly & Co. 0.78 0.73 0.53 0.57 0.58 0.62 0.60 0.67 0.52 0.58 0.63 0.79 0.62 0.70 0.66 0.77
Gilead Sciences Inc. 1.06 1.01 0.89 1.00 1.20 0.82 0.69 0.72 1.06 0.98 0.78 0.95 0.99 0.96 1.06 1.06
Johnson & Johnson 0.69 0.71 0.68 0.96 0.78 0.70 0.77 0.84 0.82 0.86 0.84 0.81 0.71 1.10 1.09 1.06
Merck & Co. Inc. 0.93 1.06 0.79 0.80 0.84 0.88 0.88 0.68 0.68 0.83 0.74 0.90 0.93 0.90 0.85 0.84
Pfizer Inc. 0.69 0.80 0.67 0.80 0.74 0.56 0.42 0.57 0.50 1.78 1.59 0.88 0.80 1.18 1.02 0.95
Regeneron Pharmaceuticals Inc. 3.28 3.19 3.57 3.90 3.86 4.34 4.43 4.40 4.82 4.31 4.53 4.54 4.16 4.37 4.20 3.95
Thermo Fisher Scientific Inc. 1.36 0.95 1.29 1.20 1.14 1.13 1.24 1.19 1.27 1.13 0.89 0.80 1.06 1.06 0.98 0.97

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).

1 Q4 2025 Calculation
Quick ratio = Total quick assets ÷ Current liabilities
= 8,660,900 ÷ 3,861,200 = 2.24

2 Click competitor name to see calculations.


The quick ratio for the analyzed period demonstrates a notable shift in trend. Initially, the ratio exhibited relative stability at a high level, followed by a consistent decline and subsequent fluctuations.

Initial Period (Mar 31, 2022 – Dec 31, 2022)
The quick ratio began at 4.37 and fluctuated between 4.14 and 4.46 throughout this period. This indicates a consistently strong ability to meet short-term obligations with highly liquid assets. The values remained relatively stable, suggesting a predictable liquidity position.
Downward Trend (Mar 31, 2023 – Jun 30, 2024)
A clear downward trend emerged starting in March 2023, with the quick ratio decreasing from 3.95 to 2.10 by June 2024. This decline suggests a weakening in the company’s immediate liquidity position, potentially due to increases in current liabilities or decreases in quick assets, or a combination of both. The rate of decline accelerated during this phase.
Fluctuations and Recent Performance (Sep 30, 2024 – Dec 31, 2025)
Following the decline, the quick ratio experienced some fluctuation, ranging from 2.08 to 2.24. While there was a slight recovery to 2.24 in December 2025, the ratio remained significantly lower than the levels observed in the initial period. This suggests that while liquidity has stabilized somewhat, it has not returned to its previous strength. The most recent value indicates a potential for continued volatility.

The observed trend suggests a change in the company’s working capital management or operational circumstances. Further investigation into the components of quick assets and current liabilities would be necessary to determine the underlying causes of these shifts and assess the potential implications for the company’s financial health.


Cash Ratio

Vertex Pharmaceuticals Inc., cash ratio calculation (quarterly data)

Microsoft Excel
Dec 31, 2025 Sep 30, 2025 Jun 30, 2025 Mar 31, 2025 Dec 31, 2024 Sep 30, 2024 Jun 30, 2024 Mar 31, 2024 Dec 31, 2023 Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022
Selected Financial Data (US$ in thousands)
Cash and cash equivalents 5,084,800 4,939,600 4,972,200 4,674,700 4,569,600 5,239,200 4,580,100 9,158,000 10,369,100 11,110,200 10,151,100 9,289,900 10,504,000 9,171,500 8,702,200 7,600,100
Marketable securities 1,523,300 1,347,400 1,410,600 1,526,500 1,546,300 1,285,300 1,215,400 1,013,300 849,200 818,000 1,085,200 1,124,200 274,500 599,200 551,200 638,000
Total cash assets 6,608,100 6,287,000 6,382,800 6,201,200 6,115,900 6,524,500 5,795,500 10,171,300 11,218,300 11,928,200 11,236,300 10,414,100 10,778,500 9,770,700 9,253,400 8,238,100
 
Current liabilities 3,861,200 4,475,300 4,138,400 3,783,200 3,564,600 3,973,100 3,547,200 3,795,900 3,547,400 3,599,400 3,352,100 3,026,200 2,742,100 2,609,300 2,556,200 2,180,200
Liquidity Ratio
Cash ratio1 1.71 1.40 1.54 1.64 1.72 1.64 1.63 2.68 3.16 3.31 3.35 3.44 3.93 3.74 3.62 3.78
Benchmarks
Cash Ratio, Competitors2
AbbVie Inc. 0.12 0.14 0.16 0.14 0.14 0.17 0.31 0.44 0.34 0.38 0.27 0.24 0.31 0.36 0.29 0.23
Amgen Inc. 0.36 0.43 0.39 0.38 0.52 0.44 0.43 0.49 0.60 2.05 2.00 2.22 0.59 0.80 0.57 0.51
Bristol-Myers Squibb Co. 0.46 0.59 0.49 0.49 0.46 0.36 0.29 0.37 0.55 0.33 0.43 0.49 0.42 0.48 0.63 0.66
Danaher Corp. 0.68 0.24 0.44 0.30 0.31 0.36 0.35 0.90 0.71 1.31 1.02 0.85 0.71 0.64 0.53 0.49
Eli Lilly & Co. 0.21 0.24 0.09 0.10 0.12 0.14 0.12 0.13 0.10 0.11 0.14 0.22 0.12 0.17 0.17 0.18
Gilead Sciences Inc. 0.65 0.60 0.47 0.64 0.83 0.43 0.26 0.36 0.64 0.57 0.48 0.56 0.57 0.54 0.61 0.62
Johnson & Johnson 0.37 0.36 0.35 0.68 0.49 0.39 0.47 0.54 0.50 0.53 0.53 0.54 0.42 0.75 0.73 0.70
Merck & Co. Inc. 0.51 0.64 0.33 0.37 0.48 0.49 0.44 0.22 0.28 0.38 0.27 0.45 0.54 0.49 0.44 0.40
Pfizer Inc. 0.37 0.41 0.35 0.48 0.48 0.23 0.16 0.29 0.27 1.42 1.29 0.55 0.54 0.82 0.70 0.61
Regeneron Pharmaceuticals Inc. 1.97 1.91 2.04 2.34 2.28 2.68 2.80 2.94 3.17 2.75 2.88 2.89 2.46 2.44 2.49 2.34
Thermo Fisher Scientific Inc. 0.67 0.24 0.50 0.45 0.42 0.46 0.60 0.52 0.58 0.43 0.22 0.22 0.50 0.26 0.17 0.23

Based on: 10-K (reporting date: 2025-12-31), 10-Q (reporting date: 2025-09-30), 10-Q (reporting date: 2025-06-30), 10-Q (reporting date: 2025-03-31), 10-K (reporting date: 2024-12-31), 10-Q (reporting date: 2024-09-30), 10-Q (reporting date: 2024-06-30), 10-Q (reporting date: 2024-03-31), 10-K (reporting date: 2023-12-31), 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31).

1 Q4 2025 Calculation
Cash ratio = Total cash assets ÷ Current liabilities
= 6,608,100 ÷ 3,861,200 = 1.71

2 Click competitor name to see calculations.


The cash ratio for the analyzed period demonstrates a general declining trend, although with some fluctuations. Initially strong, the ratio decreased over the observed timeframe, indicating a relative weakening in the company’s immediate ability to cover current liabilities with only cash and cash equivalents.

Initial Period (Mar 31, 2022 – Dec 31, 2022)
The cash ratio began at 3.78 and fluctuated between 3.62 and 3.93. This suggests a consistently strong liquidity position during this period, with the company holding approximately 3.7 to 3.9 times the amount of cash needed to cover its current liabilities. A slight increase is observed from March 2022 to December 2022.
Transition Phase (Mar 31, 2023 – Jun 30, 2023)
A moderate decline is evident, moving from 3.44 in March 2023 to 3.35 in June 2023. While still representing a healthy liquidity position, this marks the beginning of a downward trend.
Accelerated Decline (Sep 30, 2023 – Jun 30, 2024)
The cash ratio continued to decrease, falling from 3.31 to 1.63. This represents a significant reduction in the company’s ability to meet its short-term obligations with available cash. The decrease is particularly pronounced between December 2023 and March 2024.
Recent Period (Sep 30, 2024 – Dec 31, 2025)
The ratio experienced some volatility, ranging from 1.64 to 1.72, before declining to 1.40 by September 2025. A slight recovery is then observed, with the ratio increasing to 1.71 by December 2025. This suggests potential stabilization, but the ratio remains considerably lower than its initial values. The overall trend remains downward, despite the final increase.

The observed decrease in the cash ratio could be attributed to several factors, including increased current liabilities, a decrease in total cash assets, or a combination of both. Further investigation into the underlying components of these figures would be necessary to determine the specific drivers of this trend. The recent stabilization, while positive, does not negate the overall weakening of the cash position relative to short-term obligations.