Stock Analysis on Net

Cytokinetics Inc. (NASDAQ:CYTK)

This company has been moved to the archive! The financial data has not been updated since November 3, 2023.

Common Stock Valuation Ratios (Price Multiples) 
Quarterly Data

Microsoft Excel

Historical Valuation Ratios (Summary)

Cytokinetics Inc., historical price multiples (quarterly data)

Microsoft Excel
Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022 Dec 31, 2021 Sep 30, 2021 Jun 30, 2021 Mar 31, 2021 Dec 31, 2020 Sep 30, 2020 Jun 30, 2020 Mar 31, 2020 Dec 31, 2019 Sep 30, 2019 Jun 30, 2019 Mar 31, 2019 Dec 31, 2018 Sep 30, 2018 Jun 30, 2018 Mar 31, 2018
Price to earnings (P/E)
Price to operating profit (P/OP)
Price to sales (P/S) 455.70 305.78 38.47 43.37 24.10 32.28 50.13 42.19 159.98 45.97 29.69 23.86 22.07 81.16 42.16 32.88 21.30 22.26 14.99 10.47
Price to book value (P/BV) 43.79 28.04 12.19 13.84 161.16 25.62 11.75 8.01 154.23 12.72 7.48 5.16 4.73

Based on: 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31), 10-K (reporting date: 2019-12-31), 10-Q (reporting date: 2019-09-30), 10-Q (reporting date: 2019-06-30), 10-Q (reporting date: 2019-03-31), 10-K (reporting date: 2018-12-31), 10-Q (reporting date: 2018-09-30), 10-Q (reporting date: 2018-06-30), 10-Q (reporting date: 2018-03-31).


Price to Sales (P/S) Ratio
The Price to Sales ratio data begins from March 31, 2019, showing a notable increasing trend over the observed periods. Initially, the ratio stood at 10.47 and increased significantly through the quarters, reaching a peak of 159.98 by March 31, 2021. After this peak, the ratio showed fluctuations, with values oscillating between approximately 22.07 and 81.16 from late 2019 to early 2021. Following March 2021, the P/S ratio demonstrated volatility, spiking to very high levels of 305.78 and 455.7 in the most recent quarters of September and June 2023, respectively. These spikes indicate rapid changes in market capitalization relative to sales during these periods.
Price to Book Value (P/BV) Ratio
The Price to Book Value ratio data spans from March 31, 2018, to September 30, 2021, with intermittent data points and some missing values. Early in the period, the P/BV ratio increased from 4.73 to 12.72 by December 31, 2018. A dramatic surge occurred by March 31, 2019, where the ratio reached an extremely high value of 154.23, signaling a substantial market premium over book value. This was followed by a drop and moderate fluctuations with values like 8.01 and 11.75 in mid-2020, and another sharp rise up to 161.16 by December 31, 2020. The ratio then moderated with values ranging between approximately 12.19 and 43.79 through September 30, 2021. The pattern indicates periods of significant market valuation spikes relative to book value, interspersed with correction phases.
General Observations
Both price-based valuation ratios exhibited considerable volatility and heightened peaks during the period under review. The strong increases in P/S and P/BV ratios suggest episodes when the market placed a high valuation on the company relative to both sales and book value, potentially reflecting evolving investor expectations or market sentiment shifts. The data also shows some missing values, particularly in earlier periods for P/S and partial gaps in P/BV, which may limit a continuous trend analysis. Nonetheless, the pronounced spikes in recent quarters of 2023, particularly in P/S, may warrant further examination to understand the driving factors behind such elevated valuation multiples.

Price to Earnings (P/E)

Cytokinetics Inc., historical P/E calculation (quarterly data)

Microsoft Excel
Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022 Dec 31, 2021 Sep 30, 2021 Jun 30, 2021 Mar 31, 2021 Dec 31, 2020 Sep 30, 2020 Jun 30, 2020 Mar 31, 2020 Dec 31, 2019 Sep 30, 2019 Jun 30, 2019 Mar 31, 2019 Dec 31, 2018 Sep 30, 2018 Jun 30, 2018 Mar 31, 2018
No. shares of common stock outstanding1 98,053,647 95,997,998 95,640,600 95,161,391 94,631,001 94,144,097 85,652,213 84,856,037 83,882,953 83,512,670 71,738,143 71,110,576 70,779,023 70,504,701 59,469,525 59,450,437 59,081,899 58,678,894 57,721,286 54,888,369 54,710,900 54,627,997 54,197,546
Selected Financial Data (US$)
Net loss (in thousands) (129,422) (128,637) (131,289) (137,380) (142,310) (19,820) (89,445) (30,570) (76,086) (61,554) (47,104) (43,930) (3,175) (40,780) (39,405) (30,640) (29,573) (32,113) (29,366) (26,468) (22,017) (27,523) (30,281)
Earnings per share (EPS)2 -5.37 -5.62 -4.50 -4.09 -2.98 -2.29 -3.01 -2.54 -2.73 -1.87 -1.88 -1.79 -1.61 -1.99 -2.22 -2.05 -1.99 -1.87 -1.83 -1.94 0.00 0.00 0.00
Share price1, 3 36.32 31.70 39.44 43.11 37.75 51.82 38.06 35.02 41.10 31.82 24.23 18.73 16.94 21.51 15.76 14.86 11.19 13.51 9.01 6.01 7.12 7.10 8.70
Valuation Ratio
P/E ratio4
Benchmarks
P/E Ratio, Competitors5
AbbVie Inc. 38.27 30.55 34.43 22.62 19.16 19.44 21.64 22.07 27.34 30.62 39.63 40.17
Amgen Inc. 18.09 16.31 16.18 19.56 21.00 20.03 22.23 21.05 21.91 22.56 19.20 18.82
Bristol-Myers Squibb Co. 13.01 15.93 19.43 23.97 23.71 24.14 25.64 20.92
Danaher Corp. 24.76 29.99 25.00 25.65 26.65 32.73 32.15 29.94 38.81 37.87 39.26 44.49
Eli Lilly & Co. 110.43 76.21 65.16 50.08 55.53 51.05 45.29 40.66 40.07 40.34 28.77 31.95
Gilead Sciences Inc. 17.10 17.88 17.75 22.68 29.30 18.66 17.25 12.36 11.44 16.83 277.25 641.48
Johnson & Johnson 10.12 33.35 33.43 22.97 23.52 24.98 23.95 20.93 23.98 25.51 28.35 28.92
Merck & Co. Inc. 56.85 86.53 22.92 19.21 16.41 13.36 15.70 14.78 28.65 34.23 28.00 26.72
Pfizer Inc. 16.60 9.42 7.44 7.58 8.81 9.56 11.11 11.76 14.03 20.05 20.15 19.62
Regeneron Pharmaceuticals Inc. 22.35 19.48 19.77 19.68 14.98 11.67 9.15 8.37 9.96 10.38 13.27 15.09
Thermo Fisher Scientific Inc. 29.57 37.01 34.99 30.55 27.64 31.09 28.15 27.35 29.43 24.63 23.23 27.89
Vertex Pharmaceuticals Inc. 28.09 27.49 27.34 23.02 24.62 23.12 26.50 26.55 22.09 26.26 20.45 20.18

Based on: 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31), 10-K (reporting date: 2019-12-31), 10-Q (reporting date: 2019-09-30), 10-Q (reporting date: 2019-06-30), 10-Q (reporting date: 2019-03-31), 10-K (reporting date: 2018-12-31), 10-Q (reporting date: 2018-09-30), 10-Q (reporting date: 2018-06-30), 10-Q (reporting date: 2018-03-31).

1 Data adjusted for splits and stock dividends.

2 Q3 2023 Calculation
EPS = (Net lossQ3 2023 + Net lossQ2 2023 + Net lossQ1 2023 + Net lossQ4 2022) ÷ No. shares of common stock outstanding
= (-129,422,000 + -128,637,000 + -131,289,000 + -137,380,000) ÷ 98,053,647 = -5.37

3 Closing price as at the filing date of Cytokinetics Inc. Quarterly or Annual Report.

4 Q3 2023 Calculation
P/E ratio = Share price ÷ EPS
= 36.32 ÷ -5.37 =

5 Click competitor name to see calculations.


Share Price Trends
The share price demonstrated considerable volatility over the analyzed periods, beginning at $8.70 in March 2018. It initially declined to a low around $6.01 by December 2018, followed by a recovery and steady increase through mid-2019, reaching as high as $14.86 by December 2019. The price continued to generally rise with fluctuations, peaking near $41.10 in September 2021. Subsequently, the share price experienced some decline and variability, falling to approximately $31.70 in June 2023 before recovering slightly to $36.32 by September 2023. The overall trend indicates growth in market valuation with intermittent pullbacks.
Earnings per Share (EPS) Trends
Earnings per share data is only available starting in December 2018. Over this period, EPS consistently reflected negative values, indicating losses per share each quarter. The losses deepened over time, starting from approximately -$1.94 in December 2018 to a peak negative deviation of -$5.62 by September 2023. Some quarters experienced a slight reduction in losses, for example, between December 2020 and mid-2021, but the general pattern points to increasing negative earnings and worsening profitability.
Price-to-Earnings (P/E) Ratio
The P/E ratio values are absent throughout all periods, likely due to negative EPS values rendering the ratio non-applicable or undefined.
Summary of Financial Performance
The share price overall appreciated amid growing losses per share. This could suggest that market participants may have optimism about future prospects or value based on factors beyond current earnings, such as pipeline potential or strategic initiatives. The persistent negative EPS and deepening losses highlight ongoing challenges in profitability, indicating the company remains in a developmental or investment phase without current earnings generation. The absence of a meaningful P/E ratio reinforces this inference.

Price to Operating Profit (P/OP)

Cytokinetics Inc., historical P/OP calculation (quarterly data)

Microsoft Excel
Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022 Dec 31, 2021 Sep 30, 2021 Jun 30, 2021 Mar 31, 2021 Dec 31, 2020 Sep 30, 2020 Jun 30, 2020 Mar 31, 2020 Dec 31, 2019 Sep 30, 2019 Jun 30, 2019 Mar 31, 2019 Dec 31, 2018 Sep 30, 2018 Jun 30, 2018 Mar 31, 2018
No. shares of common stock outstanding1 98,053,647 95,997,998 95,640,600 95,161,391 94,631,001 94,144,097 85,652,213 84,856,037 83,882,953 83,512,670 71,738,143 71,110,576 70,779,023 70,504,701 59,469,525 59,450,437 59,081,899 58,678,894 57,721,286 54,888,369 54,710,900 54,627,997 54,197,546
Selected Financial Data (US$)
Operating income (loss) (in thousands) (122,265) (122,049) (124,473) (127,030) (108,441) (10,874) (77,857) (21,704) (69,201) (54,797) (40,611) (36,407) 5,184 (32,358) (30,362) (23,706) (23,927) (26,716) (24,518) (21,458) (17,914) (23,413) (26,131)
Operating profit per share2 -5.06 -5.02 -3.88 -3.41 -2.31 -1.91 -2.61 -2.20 -2.40 -1.52 -1.45 -1.32 -1.15 -1.57 -1.76 -1.66 -1.64 -1.54 -1.51 -1.62 0.00 0.00 0.00
Share price1, 3 36.32 31.70 39.44 43.11 37.75 51.82 38.06 35.02 41.10 31.82 24.23 18.73 16.94 21.51 15.76 14.86 11.19 13.51 9.01 6.01 7.12 7.10 8.70
Valuation Ratio
P/OP ratio4
Benchmarks
P/OP Ratio, Competitors5
AbbVie Inc. 16.55 15.26 16.15 14.78 14.52 14.12 14.57 14.21 12.41 13.12 17.23 16.32
Amgen Inc. 15.45 13.71 14.25 13.40 14.89 14.08 15.88 16.24 16.73 17.48 15.26 14.96
Bristol-Myers Squibb Co. 14.14 16.24 17.09 18.29 17.79 18.62 20.32 19.84
Danaher Corp. 23.61 27.01 21.31 20.97 20.71 25.91 26.48 25.14 32.12 30.83 32.62 36.91
Eli Lilly & Co. 93.27 69.42 59.60 43.88 46.48 39.20 36.49 35.70 37.21 42.01 31.17 32.66
Gilead Sciences Inc. 12.16 11.57 11.21 14.21 16.27 11.02 10.78 7.76 7.27 8.88 18.31 19.38
Johnson & Johnson 15.69 18.91 18.26 17.62 19.64 20.45 21.06 18.68 18.99 20.14 21.12 21.84
Merck & Co. Inc. 33.75 44.67 18.53 15.55 13.85 11.72 14.29 15.39 30.71 38.03 30.14 23.89
Pfizer Inc. 17.49 9.17 6.74 6.80 7.82 9.11 11.49 13.30 16.37 19.83 22.85 23.12
Regeneron Pharmaceuticals Inc. 21.13 19.32 18.68 18.01 12.91 9.68 7.98 7.55 9.32 9.65 13.32 14.82
Thermo Fisher Scientific Inc. 25.59 31.55 29.54 25.30 21.43 23.99 21.84 21.07 23.87 19.77 18.53 22.81
Vertex Pharmaceuticals Inc. 25.14 23.33 22.03 17.75 19.41 18.11 22.13 22.35 18.14 23.06 18.68 19.16

Based on: 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31), 10-K (reporting date: 2019-12-31), 10-Q (reporting date: 2019-09-30), 10-Q (reporting date: 2019-06-30), 10-Q (reporting date: 2019-03-31), 10-K (reporting date: 2018-12-31), 10-Q (reporting date: 2018-09-30), 10-Q (reporting date: 2018-06-30), 10-Q (reporting date: 2018-03-31).

1 Data adjusted for splits and stock dividends.

2 Q3 2023 Calculation
Operating profit per share = (Operating income (loss)Q3 2023 + Operating income (loss)Q2 2023 + Operating income (loss)Q1 2023 + Operating income (loss)Q4 2022) ÷ No. shares of common stock outstanding
= (-122,265,000 + -122,049,000 + -124,473,000 + -127,030,000) ÷ 98,053,647 = -5.06

3 Closing price as at the filing date of Cytokinetics Inc. Quarterly or Annual Report.

4 Q3 2023 Calculation
P/OP ratio = Share price ÷ Operating profit per share
= 36.32 ÷ -5.06 =

5 Click competitor name to see calculations.


The share price exhibits considerable fluctuation over the analyzed period. Initially, the price declined from $8.7 at the beginning of 2018 to a low near $6.01 by the end of 2018. However, starting in the first quarter of 2019, there is a marked upward trend, peaking at $41.10 in the third quarter of 2021. Post this peak, the price demonstrates volatility but generally remains elevated compared to the earlier years, ending at $36.32 in the third quarter of 2023. This reflects strong growth in market valuation with intermittent corrections.

Operating profit per share (OPPS) data become available starting late 2018, consistently showing negative values throughout the period. The losses per share range approximately between -$1.15 and -$5.06, indicating ongoing operating deficits. Notably, the magnitude of losses deepens over time, with a substantial dip to around -$5.06 in the third quarter of 2023, signaling increasing operational challenges or investments that have yet to generate profitability.

The P/OP (Price to Operating Profit) ratio data is absent, preventing direct evaluation of valuation relative to operating earnings. Given the persistently negative operating profit per share, the ratio likely remains undefined or non-meaningful during these quarters.

Overall, the trends suggest the company experiences sustained operating losses alongside a generally increasing share price through much of the studied period, which might reflect market optimism, potential future growth prospects, or other external factors favoring valuation beyond current operating performance. The recent increase in loss magnitude combined with share price fluctuations toward the end of the period may indicate heightened uncertainty regarding future profitability.

Share Price Trend
Decline in 2018, strong growth through 2019 to 2021, followed by volatility but elevated levels through 2023.
Operating Profit Per Share
Persistently negative from late 2018, with increasing losses culminating in the highest negative value in Q3 2023.
P/OP Ratio
Unavailable due to consistent negative operating profit.
Insight
Rising share price amid growing operating losses suggests market optimism not yet reflected in profitability, indicating potential high-risk, high-reward perceptions by investors.

Price to Sales (P/S)

Cytokinetics Inc., historical P/S calculation (quarterly data)

Microsoft Excel
Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022 Dec 31, 2021 Sep 30, 2021 Jun 30, 2021 Mar 31, 2021 Dec 31, 2020 Sep 30, 2020 Jun 30, 2020 Mar 31, 2020 Dec 31, 2019 Sep 30, 2019 Jun 30, 2019 Mar 31, 2019 Dec 31, 2018 Sep 30, 2018 Jun 30, 2018 Mar 31, 2018
No. shares of common stock outstanding1 98,053,647 95,997,998 95,640,600 95,161,391 94,631,001 94,144,097 85,652,213 84,856,037 83,882,953 83,512,670 71,738,143 71,110,576 70,779,023 70,504,701 59,469,525 59,450,437 59,081,899 58,678,894 57,721,286 54,888,369 54,710,900 54,627,997 54,197,546
Selected Financial Data (US$)
Revenues (in thousands) 378 867 4,613 1,957 2,515 88,968 1,148 55,600 5,437 2,843 6,548 6,722 41,688 3,593 3,825 5,212 6,055 7,137 8,464 9,377 10,641 6,215 5,268
Sales per share2 0.08 0.10 1.03 0.99 1.57 1.61 0.76 0.83 0.26 0.69 0.82 0.79 0.77 0.27 0.37 0.45 0.53 0.61 0.60 0.57 0.00 0.00 0.00
Share price1, 3 36.32 31.70 39.44 43.11 37.75 51.82 38.06 35.02 41.10 31.82 24.23 18.73 16.94 21.51 15.76 14.86 11.19 13.51 9.01 6.01 7.12 7.10 8.70
Valuation Ratio
P/S ratio4 455.70 305.78 38.47 43.37 24.10 32.28 50.13 42.19 159.98 45.97 29.69 23.86 22.07 81.16 42.16 32.88 21.30 22.26 14.99 10.47
Benchmarks
P/S Ratio, Competitors5
AbbVie Inc. 4.52 4.74 4.60 4.61 4.44 4.28 4.76 4.53 3.73 3.80 4.07 4.05
Amgen Inc. 5.34 5.14 5.14 5.17 5.85 5.35 5.21 5.10 5.04 5.37 5.68 5.64
Bristol-Myers Squibb Co. 2.40 2.81 3.10 3.29 3.39 3.39 3.41 3.16 2.85 3.44 3.28 3.16
Danaher Corp. 5.63 6.77 5.76 5.79 5.66 6.59 6.68 6.37 7.91 7.72 7.27 7.01
Eli Lilly & Co. 17.18 16.78 13.38 10.96 11.46 9.99 9.47 8.01 8.62 9.16 6.88 8.06
Gilead Sciences Inc. 3.69 3.61 3.70 3.86 3.64 2.84 2.86 2.85 3.11 3.30 3.31 3.24
Johnson & Johnson 4.01 4.84 4.60 4.34 4.69 4.80 5.00 4.66 4.69 5.08 5.09 5.15
Merck & Co. Inc. 4.42 4.62 5.16 4.71 4.25 3.87 4.12 3.96 4.32 4.05 4.23 3.93
Pfizer Inc. 2.51 2.58 2.32 2.37 2.63 2.77 3.00 3.18 4.04 4.78 4.84 4.50
Regeneron Pharmaceuticals Inc. 6.81 6.61 6.69 7.01 5.87 4.66 4.40 4.20 5.14 5.20 5.78 6.24
Thermo Fisher Scientific Inc. 4.05 4.87 4.81 4.73 4.40 5.40 5.20 5.39 6.45 5.54 5.13 5.52
Vertex Pharmaceuticals Inc. 10.10 9.73 9.68 8.56 9.26 8.85 8.17 8.21 6.74 7.82 8.81 8.82

Based on: 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31), 10-K (reporting date: 2019-12-31), 10-Q (reporting date: 2019-09-30), 10-Q (reporting date: 2019-06-30), 10-Q (reporting date: 2019-03-31), 10-K (reporting date: 2018-12-31), 10-Q (reporting date: 2018-09-30), 10-Q (reporting date: 2018-06-30), 10-Q (reporting date: 2018-03-31).

1 Data adjusted for splits and stock dividends.

2 Q3 2023 Calculation
Sales per share = (RevenuesQ3 2023 + RevenuesQ2 2023 + RevenuesQ1 2023 + RevenuesQ4 2022) ÷ No. shares of common stock outstanding
= (378,000 + 867,000 + 4,613,000 + 1,957,000) ÷ 98,053,647 = 0.08

3 Closing price as at the filing date of Cytokinetics Inc. Quarterly or Annual Report.

4 Q3 2023 Calculation
P/S ratio = Share price ÷ Sales per share
= 36.32 ÷ 0.08 = 455.70

5 Click competitor name to see calculations.


Share Price Trend
The share price demonstrated notable fluctuations over the analyzed periods. Starting at $8.70 in March 2018, it experienced a decline reaching a low of $6.01 by December 2018. Subsequently, a general uptrend ensued, marked by periods of volatility, culminating in a peak of $51.82 in June 2022. Following this peak, the price exhibited a downward correction with values around $31.70 to $36.32 in the later quarters of 2023. Overall, the share price more than quadrupled from its initial value in the observed timeframe, albeit with significant interim volatility.
Sales Per Share Pattern
Sales per share data, available from March 2019 onwards, reflected variability without a consistent upward or downward trend. Initial values hovered around $0.57 to $0.61, dipping to as low as $0.08 in the September 2023 quarter. There were intermittent peaks, notably $1.61 in September 2022, indicating episodic increases in revenue per share. The general pattern suggests fluctuating sales performance with no sustained growth trajectory.
Price-to-Sales (P/S) Ratio Dynamics
The P/S ratio exhibited significant volatility, with several sharp increases and decreases. Starting at 10.47 in March 2019, the ratio surged dramatically to values exceeding 300 in September 2023 and an exceptional 455.7 in the subsequent quarter. These spikes contrast with intermediate values that generally ranged between the low 20s and mid-50s. The marked increases in P/S ratios in recent quarters imply a substantial rise in market valuation relative to sales, possibly due to declining sales per share coupled with sustained or increasing share prices.
Overall Insights
The data indicates that while the share price increased substantially over the period, sales per share did not uniformly support this growth, exhibiting variability and a recent declining trend. This divergence resulted in pronounced increases in the P/S ratio, signaling that the stock has become more highly valued relative to its sales performance. Such patterns may suggest heightened investor expectations or speculative behavior rather than improvements in fundamental sales metrics.

Price to Book Value (P/BV)

Cytokinetics Inc., historical P/BV calculation (quarterly data)

Microsoft Excel
Sep 30, 2023 Jun 30, 2023 Mar 31, 2023 Dec 31, 2022 Sep 30, 2022 Jun 30, 2022 Mar 31, 2022 Dec 31, 2021 Sep 30, 2021 Jun 30, 2021 Mar 31, 2021 Dec 31, 2020 Sep 30, 2020 Jun 30, 2020 Mar 31, 2020 Dec 31, 2019 Sep 30, 2019 Jun 30, 2019 Mar 31, 2019 Dec 31, 2018 Sep 30, 2018 Jun 30, 2018 Mar 31, 2018
No. shares of common stock outstanding1 98,053,647 95,997,998 95,640,600 95,161,391 94,631,001 94,144,097 85,652,213 84,856,037 83,882,953 83,512,670 71,738,143 71,110,576 70,779,023 70,504,701 59,469,525 59,450,437 59,081,899 58,678,894 57,721,286 54,888,369 54,710,900 54,627,997 54,197,546
Selected Financial Data (US$)
Stockholders’ equity (deficit) (in thousands) (438,801) (333,115) (229,020) (107,900) (15,977) 111,414 116,261 243,863 249,020 16,489 67,846 113,383 149,605 (78,080) (45,711) (10,937) (19,869) (4,896) 3,372 25,934 52,069 75,170 99,599
Book value per share (BVPS)2 -4.48 -3.47 -2.39 -1.13 -0.17 1.18 1.36 2.87 2.97 0.20 0.95 1.59 2.11 -1.11 -0.77 -0.18 -0.34 -0.08 0.06 0.47 0.95 1.38 1.84
Share price1, 3 36.32 31.70 39.44 43.11 37.75 51.82 38.06 35.02 41.10 31.82 24.23 18.73 16.94 21.51 15.76 14.86 11.19 13.51 9.01 6.01 7.12 7.10 8.70
Valuation Ratio
P/BV ratio4 43.79 28.04 12.19 13.84 161.16 25.62 11.75 8.01 154.23 12.72 7.48 5.16 4.73
Benchmarks
P/BV Ratio, Competitors5
AbbVie Inc. 20.61 20.62 19.68 15.52 16.06 16.76 16.59 16.53 15.20 16.23 14.91 14.18 10.93 11.31
Amgen Inc. 17.87 19.19 23.95 35.01 39.30 54.46 138.87 18.51 14.95 15.72 14.57 14.53 11.57 13.67 14.33
Bristol-Myers Squibb Co. 3.72 3.97 4.46 4.88 4.85 4.90 5.07 4.07 3.48 4.15 3.73 3.55 2.87 2.82 2.77
Danaher Corp. 2.78 3.65 3.33 3.64 3.77 4.36 4.36 4.16 5.11 4.82 4.46 3.93 4.38 3.90 3.68
Eli Lilly & Co. 49.10 44.75 33.11 29.36 33.27 34.00 29.75 25.28 30.85 38.00 25.41 35.07 26.02 35.12 47.73
Gilead Sciences Inc. 4.50 4.63 4.72 4.90 4.63 3.82 3.91 3.65 3.94 4.41 4.40 4.33 4.30 4.79 4.40
Johnson & Johnson 4.92 5.79 6.00 5.37 6.04 6.01 6.36 5.90 6.10 6.51 6.51 6.72 5.93 6.19 6.46
Merck & Co. Inc. 6.35 6.96 6.38 6.07 5.63 5.12 5.44 5.05 5.76 5.73 7.30 7.46 6.97 7.47 7.43
Pfizer Inc. 1.80 2.04 2.14 2.48 2.83 3.21 3.37 3.35 3.69 3.78 3.27 2.98 3.10 3.31 3.16
Regeneron Pharmaceuticals Inc. 3.58 3.49 3.52 3.77 3.75 3.21 3.65 3.60 4.04 4.26 4.44 4.81 6.21 7.34 5.33
Thermo Fisher Scientific Inc. 3.88 4.84 4.99 4.83 4.46 5.47 5.23 5.18 6.51 5.75 5.25 5.15 5.89 5.48 4.56
Vertex Pharmaceuticals Inc. 5.90 5.98 6.18 5.50 6.18 6.19 5.95 6.16 5.04 5.69 6.29 6.30 6.66 9.42 10.23

Based on: 10-Q (reporting date: 2023-09-30), 10-Q (reporting date: 2023-06-30), 10-Q (reporting date: 2023-03-31), 10-K (reporting date: 2022-12-31), 10-Q (reporting date: 2022-09-30), 10-Q (reporting date: 2022-06-30), 10-Q (reporting date: 2022-03-31), 10-K (reporting date: 2021-12-31), 10-Q (reporting date: 2021-09-30), 10-Q (reporting date: 2021-06-30), 10-Q (reporting date: 2021-03-31), 10-K (reporting date: 2020-12-31), 10-Q (reporting date: 2020-09-30), 10-Q (reporting date: 2020-06-30), 10-Q (reporting date: 2020-03-31), 10-K (reporting date: 2019-12-31), 10-Q (reporting date: 2019-09-30), 10-Q (reporting date: 2019-06-30), 10-Q (reporting date: 2019-03-31), 10-K (reporting date: 2018-12-31), 10-Q (reporting date: 2018-09-30), 10-Q (reporting date: 2018-06-30), 10-Q (reporting date: 2018-03-31).

1 Data adjusted for splits and stock dividends.

2 Q3 2023 Calculation
BVPS = Stockholders’ equity (deficit) ÷ No. shares of common stock outstanding
= -438,801,000 ÷ 98,053,647 = -4.48

3 Closing price as at the filing date of Cytokinetics Inc. Quarterly or Annual Report.

4 Q3 2023 Calculation
P/BV ratio = Share price ÷ BVPS
= 36.32 ÷ -4.48 =

5 Click competitor name to see calculations.


The analyzed financial data reveals notable fluctuations and trends in the share price, book value per share (BVPS), and the price-to-book value (P/BV) ratio over the observed periods.

Share Price
The share price demonstrates an overall upward trend from March 31, 2018, through September 30, 2023, starting at US$8.7 and reaching values around US$36.32 in the latest period. It exhibits periods of volatility, with notable increases between mid-2019 and mid-2021, peaking at US$41.1 on September 30, 2021, followed by fluctuations including a decline towards the end of 2021 and another rise in the first half of 2022. The price then shows variability with some downward adjustments and rebounds in 2023.
Book Value per Share (BVPS)
The BVPS displays significant variability and oscillates between positive and negative values throughout the timeline. Initial values start positively at US$1.84 as of March 31, 2018, decreasing progressively to negative territory by mid-2019 (-US$0.08 June 30, 2019). The pattern continues oscillating, with brief recovery periods such as US$2.11 on September 30, 2020, followed by declines and negative values resurfacing later, reaching as low as -US$4.48 by September 30, 2023. This indicates persistent fluctuations in equity value per share, with no sustained positive trend, suggesting possible challenges in asset valuation or retained earnings.
Price-to-Book Value (P/BV) Ratio
The P/BV ratio shows extreme volatility and large spikes during certain periods. Initial values range from 4.73 to 12.72 in 2018, but by March 31, 2019, an outlier value of 154.23 appears, indicating the share price vastly exceeded the book value at that point. However, the data has several missing values in subsequent periods, complicating a continuous analysis. When available, P/BV peaks again at 161.16 in September 30, 2021, signifying exceptionally high market valuation relative to book value. These sporadic high ratios reflect the impact of negative or near-zero BVPS, which inflates the P/BV ratio given the denominator's effect. The series later shows a decline to lower double-digit values, illustrating some normalization following peaks.

In summary, the stock price exhibits growth and marked volatility over the observed timeline, while book value per share fluctuates significantly, including extended negative values, indicative of underlying financial variability. The P/BV ratio's extreme spikes correlate with BVPS volatility and negative book values, highlighting irregular valuation metrics that may warrant deeper investigation into the company's financial structure and asset management practices.