Net Profit Margin
since 2005
Calculation
Cytokinetics Inc., net profit margin, long-term trends, calculation
| Net profit margin | = | 100 | × | Net income (loss)1 | ÷ | Revenues1 | |
|---|---|---|---|---|---|---|---|
| Dec 31, 2022 | -411.21% | = | 100 | × | (388,955) | ÷ | 94,588) |
| Dec 31, 2021 | -305.72% | = | 100 | × | (215,314) | ÷ | 70,428) |
| Dec 31, 2020 | -228.00% | = | 100 | × | (127,290) | ÷ | 55,828) |
| Dec 31, 2019 | -452.93% | = | 100 | × | (121,692) | ÷ | 26,868) |
| Dec 31, 2018 | -337.41% | = | 100 | × | (106,289) | ÷ | 31,501) |
| Dec 31, 2017 | -955.94% | = | 100 | × | (127,790) | ÷ | 13,368) |
| Dec 31, 2016 | 15.46% | = | 100 | × | 16,453) | ÷ | 106,407) |
| Dec 31, 2015 | -130.86% | = | 100 | × | (37,501) | ÷ | 28,658) |
| Dec 31, 2014 | -31.20% | = | 100 | × | (14,646) | ÷ | 46,940) |
| Dec 31, 2013 | -110.01% | = | 100 | × | (33,717) | ÷ | 30,648) |
| Dec 31, 2012 | -534.07% | = | 100 | × | (40,370) | ÷ | 7,559) |
| Dec 31, 2011 | -1,196.50% | = | 100 | × | (47,860) | ÷ | 4,000) |
| Dec 31, 2010 | -1,912.57% | = | 100 | × | (49,287) | ÷ | 2,577) |
| Dec 31, 2009 | 30.10% | = | 100 | × | 24,544) | ÷ | 81,538) |
| Dec 31, 2008 | -453.90% | = | 100 | × | (56,374) | ÷ | 12,420) |
| Dec 31, 2007 | -358.93% | = | 100 | × | (48,894) | ÷ | 13,622) |
| Dec 31, 2006 | -1,826.51% | = | 100 | × | (57,115) | ÷ | 3,127) |
| Dec 31, 2005 | -474.10% | = | 100 | × | (42,252) | ÷ | 8,912) |
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31), 10-K (reporting date: 2016-12-31), 10-K (reporting date: 2015-12-31), 10-K (reporting date: 2014-12-31), 10-K (reporting date: 2013-12-31), 10-K (reporting date: 2012-12-31), 10-K (reporting date: 2011-12-31), 10-K (reporting date: 2010-12-31), 10-K (reporting date: 2009-12-31), 10-K (reporting date: 2008-12-31), 10-K (reporting date: 2007-12-31), 10-K (reporting date: 2006-12-31), 10-K (reporting date: 2005-12-31).
1 US$ in thousands
The net profit margin from 2005 to 2022 is characterized by persistent negative values and extreme volatility, reflecting an operational structure where expenses consistently and significantly exceed total revenues.
- Historical Margin Volatility
- Between 2005 and 2015, the net profit margin exhibited severe fluctuations. Extreme negative peaks occurred in 2006 (-1,826.51%) and 2010 (-1,912.57%), periods during which revenues were at their lowest levels. Two anomalous instances of profitability were recorded in 2009 (30.10%) and 2016 (15.46%), though these remained isolated events within a broader trend of net losses.
- Recent Financial Trajectory
- From 2017 to 2022, a widening gap between revenue growth and expenditure is observed. Although revenues increased from 13.3 million in 2017 to 94.5 million in 2022, the net loss expanded more aggressively, accelerating from 127.7 million in 2017 to 388.9 million in 2022. This resulted in a deterioration of the net profit margin to -411.21% by the end of the analyzed period.
- Revenue and Loss Correlation
- The data indicates that revenue growth has not served as a stabilizer for the net profit margin. While the most extreme negative percentages occurred during years of very low revenue, the most recent period shows that higher revenue volumes are currently coinciding with the largest absolute net losses in the company's history, maintaining a deeply negative margin profile.
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Comparison to Competitors
Cytokinetics Inc., net profit margin, long-term trends, comparison to competitors
| Cytokinetics Inc. | AbbVie Inc. | Amgen Inc. | Bristol-Myers Squibb Co. | Danaher Corp. | Eli Lilly & Co. | Gilead Sciences Inc. | Johnson & Johnson | Merck & Co. Inc. | Pfizer Inc. | Regeneron Pharmaceuticals Inc. | Thermo Fisher Scientific Inc. | Vertex Pharmaceuticals Inc. | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dec 31, 2022 | -411.21% | 20.39% | 26.42% | 13.71% | 22.91% | 21.88% | 17.02% | 18.90% | 24.49% | 31.01% | 35.64% | 15.47% | 37.20% |
| Dec 31, 2021 | -305.72% | 20.54% | 24.25% | 15.08% | 21.84% | 19.71% | 23.05% | 22.26% | 26.79% | 26.76% | 50.25% | 19.70% | 30.92% |
| Dec 31, 2020 | -228.00% | 10.08% | 29.97% | -21.20% | 16.36% | 25.24% | 0.51% | 17.82% | 14.72% | 22.53% | 41.35% | 19.79% | 43.70% |
| Dec 31, 2019 | -452.93% | 23.69% | 35.32% | 13.15% | 16.80% | 37.27% | 24.35% | 18.42% | 21.01% | 31.45% | 26.91% | 14.47% | 28.27% |
| Dec 31, 2018 | -337.41% | 17.36% | 37.25% | 21.81% | 13.33% | 13.16% | 25.16% | 18.75% | 14.71% | 20.79% | 36.42% | 12.06% | 68.80% |
| Dec 31, 2017 | -955.94% | 18.82% | 9.08% | 4.85% | 13.60% | -0.89% | 18.03% | 1.70% | 5.97% | 40.55% | 20.41% | 10.64% | 10.59% |
| Dec 31, 2016 | 15.46% | 23.22% | 35.27% | 22.94% | 15.13% | 12.90% | 45.07% | 23.01% | 9.85% | 13.66% | 18.42% | 11.06% | -6.58% |
| Dec 31, 2015 | -130.86% | 22.50% | 33.13% | 9.45% | 16.33% | 12.07% | 56.32% | 21.99% | 11.25% | 14.25% | 15.50% | 11.64% | -53.89% |
| Dec 31, 2014 | -31.20% | 8.89% | 26.69% | 12.62% | 13.05% | 12.19% | 49.44% | 21.96% | 28.22% | 18.42% | 12.34% | 11.22% | -127.25% |
| Dec 31, 2013 | -110.01% | 21.97% | 27.93% | 15.64% | 14.10% | 20.27% | 28.46% | 19.40% | 10.00% | 42.65% | 20.16% | 9.73% | -36.72% |
| Dec 31, 2012 | -534.07% | 28.70% | 26.11% | 11.12% | 13.10% | 18.09% | 27.57% | 16.14% | 13.05% | 24.70% | 54.43% | 9.42% | -7.01% |
| Dec 31, 2011 | -1,196.50% | — | 24.08% | 17.46% | 13.50% | 17.90% | 34.60% | 14.87% | 13.05% | 14.84% | -49.74% | 11.34% | 2.10% |
| Dec 31, 2010 | -1,912.57% | — | 31.56% | 15.92% | 13.58% | 21.97% | 39.26% | 21.65% | 1.87% | 12.18% | -22.76% | 9.60% | -526.35% |
| Dec 31, 2009 | 30.10% | — | 32.09% | 56.42% | 10.30% | 19.82% | 40.74% | 19.82% | 47.04% | 17.27% | -17.88% | 8.41% | -630.27% |
| Dec 31, 2008 | -453.90% | — | 28.57% | 25.47% | 10.38% | -10.17% | 39.55% | 20.31% | 32.74% | 16.78% | -34.69% | 9.47% | -262.02% |
| Dec 31, 2007 | -358.93% | — | 22.12% | 11.19% | 12.42% | 15.85% | 43.27% | 17.31% | 13.54% | 16.82% | -84.46% | 7.81% | -196.61% |
| Dec 31, 2006 | -1,826.51% | — | 21.29% | 8.85% | 11.69% | 16.97% | -45.98% | 20.73% | 19.59% | 39.98% | -161.30% | 4.46% | -95.63% |
| Dec 31, 2005 | -474.10% | — | 30.56% | 15.62% | 11.24% | 13.52% | 44.99% | 20.61% | 21.04% | 15.76% | -144.19% | 8.48% | -126.43% |
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31), 10-K (reporting date: 2016-12-31), 10-K (reporting date: 2015-12-31), 10-K (reporting date: 2014-12-31), 10-K (reporting date: 2013-12-31), 10-K (reporting date: 2012-12-31), 10-K (reporting date: 2011-12-31), 10-K (reporting date: 2010-12-31), 10-K (reporting date: 2009-12-31), 10-K (reporting date: 2008-12-31), 10-K (reporting date: 2007-12-31), 10-K (reporting date: 2006-12-31), 10-K (reporting date: 2005-12-31).
Comparison to Sector (Pharmaceuticals, Biotechnology & Life Sciences)
Cytokinetics Inc., net profit margin, long-term trends, comparison to sector (pharmaceuticals, biotechnology & life sciences)
| Cytokinetics Inc. | Pharmaceuticals, Biotechnology & Life Sciences | |
|---|---|---|
| Dec 31, 2022 | -411.21% | 22.55% |
| Dec 31, 2021 | -305.72% | 23.38% |
| Dec 31, 2020 | -228.00% | 14.07% |
| Dec 31, 2019 | -452.93% | 23.22% |
| Dec 31, 2018 | -337.41% | 19.82% |
| Dec 31, 2017 | -955.94% | 13.06% |
| Dec 31, 2016 | 15.46% | 20.78% |
| Dec 31, 2015 | -130.86% | 21.17% |
| Dec 31, 2014 | -31.20% | 21.24% |
| Dec 31, 2013 | -110.01% | 21.99% |
| Dec 31, 2012 | -534.07% | 18.53% |
| Dec 31, 2011 | -1,196.50% | 15.70% |
| Dec 31, 2010 | -1,912.57% | 15.16% |
| Dec 31, 2009 | 30.10% | 25.73% |
| Dec 31, 2008 | -453.90% | 18.17% |
| Dec 31, 2007 | -358.93% | 15.90% |
| Dec 31, 2006 | -1,826.51% | 22.24% |
| Dec 31, 2005 | -474.10% | 18.33% |
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31), 10-K (reporting date: 2016-12-31), 10-K (reporting date: 2015-12-31), 10-K (reporting date: 2014-12-31), 10-K (reporting date: 2013-12-31), 10-K (reporting date: 2012-12-31), 10-K (reporting date: 2011-12-31), 10-K (reporting date: 2010-12-31), 10-K (reporting date: 2009-12-31), 10-K (reporting date: 2008-12-31), 10-K (reporting date: 2007-12-31), 10-K (reporting date: 2006-12-31), 10-K (reporting date: 2005-12-31).
Comparison to Industry (Health Care)
Cytokinetics Inc., net profit margin, long-term trends, comparison to industry (health care)
| Cytokinetics Inc. | Health Care | |
|---|---|---|
| Dec 31, 2022 | -411.21% | 14.65% |
| Dec 31, 2021 | -305.72% | 15.24% |
| Dec 31, 2020 | -228.00% | 10.27% |
| Dec 31, 2019 | -452.93% | 14.56% |
| Dec 31, 2018 | -337.41% | 12.61% |
| Dec 31, 2017 | -955.94% | 9.26% |
| Dec 31, 2016 | 15.46% | 12.80% |
| Dec 31, 2015 | -130.86% | 13.94% |
| Dec 31, 2014 | -31.20% | 14.40% |
| Dec 31, 2013 | -110.01% | 15.04% |
| Dec 31, 2012 | -534.07% | 13.92% |
| Dec 31, 2011 | -1,196.50% | 12.06% |
| Dec 31, 2010 | -1,912.57% | 11.90% |
| Dec 31, 2009 | 30.10% | 17.77% |
| Dec 31, 2008 | -453.90% | 13.00% |
| Dec 31, 2007 | -358.93% | 12.52% |
| Dec 31, 2006 | -1,826.51% | 15.30% |
| Dec 31, 2005 | -474.10% | 14.61% |
Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31), 10-K (reporting date: 2016-12-31), 10-K (reporting date: 2015-12-31), 10-K (reporting date: 2014-12-31), 10-K (reporting date: 2013-12-31), 10-K (reporting date: 2012-12-31), 10-K (reporting date: 2011-12-31), 10-K (reporting date: 2010-12-31), 10-K (reporting date: 2009-12-31), 10-K (reporting date: 2008-12-31), 10-K (reporting date: 2007-12-31), 10-K (reporting date: 2006-12-31), 10-K (reporting date: 2005-12-31).