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Cytokinetics Inc. (NASDAQ:CYTK)

This company has been moved to the archive! The financial data has not been updated since November 3, 2023.

Income Statement

Cytokinetics Inc., consolidated income statement

US$ in thousands

Microsoft Excel
12 months ended: Dec 31, 2022 Dec 31, 2021 Dec 31, 2020 Dec 31, 2019 Dec 31, 2018
Research and development revenues 6,588 10,572 16,527 26,868 26,368
License revenues — 54,856 36,501 — 5,133
Milestone revenues 1,000 5,000 2,800 — —
Realization of revenue participation right purchase agreement 87,000 — — — —
Revenues 94,588 70,428 55,828 26,868 31,501
Research and development (240,813) (159,938) (96,951) (86,125) (89,135)
General and administrative (177,977) (96,803) (52,820) (39,610) (31,282)
Operating expenses (418,790) (256,741) (149,771) (125,735) (120,417)
Operating loss (324,202) (186,313) (93,943) (98,867) (88,916)
Interest expense (19,414) (16,440) (15,963) (6,623) (3,797)
Loss on settlement of debt (24,939) — — — —
Non-cash interest expense on liabilities related to revenue participation right purchase agreements (31,742) (12,892) (22,713) (20,737) (17,767)
Interest and other income, net 11,342 331 5,329 4,535 4,191
Loss, before income tax provision (388,955) (215,314) (127,290) (121,692) (106,289)
Income tax provision — — — — —
Net loss (388,955) (215,314) (127,290) (121,692) (106,289)

Based on: 10-K (reporting date: 2022-12-31), 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31).


The financial trajectory from 2018 to 2022 is characterized by a significant increase in total revenues alongside a disproportionate escalation in operating expenses, leading to widening net losses.

Revenue Composition and Trends
Total revenues grew from US$ 31.5 million in 2018 to US$ 94.6 million in 2022. This growth was not uniform across all streams. Research and development revenues exhibited a consistent downward trend, falling from US$ 26.4 million in 2018 to US$ 6.6 million in 2022. Conversely, license revenues emerged as a significant contributor, peaking at US$ 54.9 million in 2021. The revenue spike in 2022 was primarily driven by a one-time realization of a revenue participation right purchase agreement totaling US$ 87 million.
Operating Expense Escalation
Operating expenses increased substantially over the five-year period, rising from US$ 120.4 million in 2018 to US$ 418.8 million in 2022. Research and development spending saw a marked increase, accelerating from US$ 89.1 million in 2018 to US$ 240.8 million in 2022. General and administrative expenses followed a similar upward trajectory, growing from US$ 31.3 million in 2018 to US$ 178.0 million in 2022, indicating a significant increase in the company's operational scale or overhead.
Profitability and Loss Trajectory
The operating loss expanded significantly, moving from US$ 88.9 million in 2018 to US$ 324.2 million in 2022. The net loss followed this pattern, widening from US$ 106.3 million in 2018 to US$ 389.0 million in 2022. The rate of loss acceleration increased sharply after 2020, coinciding with the steep rise in both research and administrative expenditures.
Non-Operating Financial Impacts
Interest expenses grew steadily from US$ 3.8 million in 2018 to US$ 19.4 million in 2022. Additionally, non-cash interest expenses related to revenue participation right purchase agreements fluctuated, reaching a peak of US$ 31.7 million in 2022. The net loss in 2022 was further impacted by a one-time loss on the settlement of debt amounting to US$ 24.9 million.

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