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Biogen Inc. (NASDAQ:BIIB)

This company has been moved to the archive! The financial data has not been updated since October 25, 2022.

DuPont Analysis: Disaggregation of ROE, ROA, and Net Profit Margin

Microsoft Excel

Two-Component Disaggregation of ROE

Biogen Inc., decomposition of ROE

Microsoft Excel
ROE = ROA × Financial Leverage
Dec 31, 2021 14.28% = 6.52% × 2.19
Dec 31, 2020 37.39% = 16.25% × 2.30
Dec 31, 2019 44.13% = 21.62% × 2.04
Dec 31, 2018 33.98% = 17.52% × 1.94
Dec 31, 2017 20.13% = 10.73% × 1.88

Based on: 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31).


The analysis of the two-component DuPont disaggregation from 2017 to 2021 reveals a period of significant volatility in profitability, characterized by a sharp peak in 2019 followed by a substantial contraction in returns by the end of the period.

Return on Assets (ROA)
An upward trajectory is observed between 2017 and 2019, with ROA increasing from 10.73% to a peak of 21.62%. This indicates a period of improving operational efficiency and asset utilization. However, this trend reversed after 2019, with a decline to 16.25% in 2020 and a sharp drop to 6.52% by December 31, 2021, suggesting a significant reduction in the company's ability to generate earnings from its asset base.
Financial Leverage
A consistent increase in financial leverage is noted from 2017 through 2020, rising from a ratio of 1.88 to a peak of 2.30. This trend indicates a gradual increase in the use of debt or a reduction in equity relative to total assets to amplify returns. A slight contraction in leverage occurred in 2021, with the ratio declining to 2.19.
Return on Equity (ROE)
The Return on Equity exhibited extreme fluctuations, mirroring the movement of ROA but amplified by the increasing financial leverage. ROE grew from 20.13% in 2017 to a maximum of 44.13% in 2019. The subsequent decline was steep, falling to 37.39% in 2020 and ending at 14.28% in 2021. The data suggests that while leverage initially helped boost equity returns, it was insufficient to offset the precipitous decline in ROA during the final two years of the analyzed period.

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Three-Component Disaggregation of ROE

Biogen Inc., decomposition of ROE

Microsoft Excel
ROE = Net Profit Margin × Asset Turnover × Financial Leverage
Dec 31, 2021 14.28% = 14.17% × 0.46 × 2.19
Dec 31, 2020 37.39% = 29.76% × 0.55 × 2.30
Dec 31, 2019 44.13% = 40.96% × 0.53 × 2.04
Dec 31, 2018 33.98% = 32.93% × 0.53 × 1.94
Dec 31, 2017 20.13% = 20.69% × 0.52 × 1.88

Based on: 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31).


The Return on Equity (ROE) exhibited significant volatility between 2017 and 2021, characterized by a substantial ascent to a peak of 44.13% in 2019, followed by a precipitous decline to 14.28% by the end of 2021. The trajectory indicates that shareholder returns were driven by fluctuating operational profitability rather than stable asset utilization or capital structure changes.

Net Profit Margin
Profitability acted as the primary catalyst for the observed shifts in ROE. A strong upward trend was evident from 2017 through 2019, with margins expanding from 20.69% to a peak of 40.96%. This growth phase was followed by a severe contraction, with the margin falling to 29.76% in 2020 and further collapsing to 14.17% in 2021, directly correlating with the overall decline in ROE.
Financial Leverage
The financial leverage ratio showed a steady increase from 1.88 in 2017 to a peak of 2.30 in 2020. This indicates a deliberate increase in the use of debt to amplify equity returns during the period of margin expansion. A slight correction to 2.19 occurred in 2021, suggesting a minor reduction in leverage that coincided with the broader decline in financial performance.
Asset Turnover
Asset efficiency remained relatively stagnant throughout the period, showing the least variance of the three components. The ratio fluctuated slightly between a low of 0.46 and a high of 0.55. The stability of this metric indicates that the volatility in ROE was not a result of changes in the company's ability to generate revenue from its asset base, although the drop to 0.46 in 2021 exerted additional downward pressure on the final ROE figure.

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Five-Component Disaggregation of ROE

Biogen Inc., decomposition of ROE

Microsoft Excel
ROE = Tax Burden × Interest Burden × EBIT Margin × Asset Turnover × Financial Leverage
Dec 31, 2021 14.28% = 0.97 × 0.86 × 16.96% × 0.46 × 2.19
Dec 31, 2020 37.39% = 0.80 × 0.96 × 38.79% × 0.55 × 2.30
Dec 31, 2019 44.13% = 0.84 × 0.97 × 50.31% × 0.53 × 2.04
Dec 31, 2018 33.98% = 0.76 × 0.97 × 45.02% × 0.53 × 1.94
Dec 31, 2017 20.13% = 0.51 × 0.95 × 42.76% × 0.52 × 1.88

Based on: 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31).


The Return on Equity (ROE) followed a trajectory of significant growth followed by a sharp contraction, increasing from 20.13% in 2017 to a peak of 44.13% in 2019, before falling to 14.28% by the end of 2021. An analysis of the five-component disaggregation indicates that while tax efficiency and financial leverage provided support, a precipitous decline in operating margins served as the primary driver for the reduction in shareholder returns.

Operating Profitability
The EBIT Margin exhibited substantial volatility, climbing from 42.76% in 2017 to a peak of 50.31% in 2019. This was followed by a severe downward trend, with the margin contracting to 38.79% in 2020 and further collapsing to 16.96% in 2021, representing the most significant negative impact on the overall ROE.
Tax Efficiency
A consistent upward trend is observed in the Tax Burden ratio, which improved from 0.51 in 2017 to 0.97 in 2021. This indicates a significant increase in the proportion of pre-tax income retained as net income, suggesting a lower effective tax rate over the five-year period.
Financial Leverage
Financial Leverage increased steadily from 1.88 in 2017 to a peak of 2.30 in 2020, before slightly moderating to 2.19 in 2021. This expansion suggests an increased reliance on debt to finance assets, which acted to amplify the return on equity during the period of margin expansion.
Asset Efficiency
Asset Turnover remained relatively stable between 2017 and 2020, fluctuating within a narrow range of 0.52 to 0.55. However, a decline to 0.46 was recorded in 2021, reflecting a decrease in the efficiency of asset utilization in generating revenue.
Interest Burden
The Interest Burden remained high and stable, hovering between 0.95 and 0.97 from 2017 through 2020, suggesting that interest expenses had a negligible effect on operating profits. A decline to 0.86 in 2021 indicates a relative increase in the burden of interest payments during that final period.

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Two-Component Disaggregation of ROA

Biogen Inc., decomposition of ROA

Microsoft Excel
ROA = Net Profit Margin × Asset Turnover
Dec 31, 2021 6.52% = 14.17% × 0.46
Dec 31, 2020 16.25% = 29.76% × 0.55
Dec 31, 2019 21.62% = 40.96% × 0.53
Dec 31, 2018 17.52% = 32.93% × 0.53
Dec 31, 2017 10.73% = 20.69% × 0.52

Based on: 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31).


The Return on Assets (ROA) exhibited significant volatility over the five-year period, peaking in 2019 before experiencing a sharp contraction by 2021. The two-component disaggregation reveals that fluctuations in ROA were primarily driven by changes in profitability rather than asset efficiency.

Net Profit Margin
Profitability showed a strong upward trajectory from 2017 (20.69%) to a peak of 40.96% in 2019. This trend reversed sharply thereafter, with margins declining to 29.76% in 2020 and further dropping to 14.17% by 2021, indicating a substantial erosion of bottom-line efficiency.
Asset Turnover
Asset utilization remained relatively stagnant between 2017 and 2020, fluctuating narrowly between 0.52 and 0.55. A noticeable decrease occurred in 2021, where the ratio fell to 0.46, indicating a decline in the revenue-generating efficiency of the asset base.
Return on Assets (ROA)
The ROA trajectory closely mirrored the profit margin, rising from 10.73% in 2017 to 21.62% in 2019. The subsequent decline to 6.52% in 2021 represents a significant reduction in overall operational effectiveness, resulting from the simultaneous collapse of net margins and a dip in asset turnover.

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Four-Component Disaggregation of ROA

Biogen Inc., decomposition of ROA

Microsoft Excel
ROA = Tax Burden × Interest Burden × EBIT Margin × Asset Turnover
Dec 31, 2021 6.52% = 0.97 × 0.86 × 16.96% × 0.46
Dec 31, 2020 16.25% = 0.80 × 0.96 × 38.79% × 0.55
Dec 31, 2019 21.62% = 0.84 × 0.97 × 50.31% × 0.53
Dec 31, 2018 17.52% = 0.76 × 0.97 × 45.02% × 0.53
Dec 31, 2017 10.73% = 0.51 × 0.95 × 42.76% × 0.52

Based on: 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31).


The Return on Assets (ROA) followed a bell-shaped trajectory over the five-year period, peaking at 21.62% in 2019 before contracting significantly to 6.52% by the end of 2021. The analysis of the four-component disaggregation reveals that while tax efficiency improved, the overall decline in ROA was primarily driven by a severe erosion of operating profitability and a late-period decrease in asset utilization.

Tax Burden
A consistent upward trend is observed in the tax burden ratio, which rose from 0.51 in 2017 to 0.97 in 2021. This improvement indicates that a larger portion of pre-tax income was retained as net income over time, effectively acting as a buffer that partially offset the declines in operational performance.
Interest Burden
The interest burden remained relatively stable between 0.95 and 0.97 from 2017 through 2020, suggesting that interest expenses had a negligible impact on earnings. However, a decrease to 0.86 in 2021 indicates an increase in the relative cost of debt servicing compared to operating income.
EBIT Margin
The operating margin served as the primary volatility driver for ROA. After an initial expansion from 42.76% in 2017 to a peak of 50.31% in 2019, the margin experienced a sharp decline, falling to 38.79% in 2020 and further collapsing to 16.96% in 2021. This substantial contraction suggests a significant increase in operating expenses or a decrease in core revenue efficiency.
Asset Turnover
Asset utilization remained remarkably stable for the first four years, fluctuating narrowly between 0.52 and 0.55. A decline to 0.46 occurred in 2021, coinciding with the drop in EBIT margin, which indicates a reduction in the company's ability to generate revenue from its asset base during the final year of the period.

In summary, the deterioration of ROA from its 2019 peak was not a result of tax or interest pressures, but rather a combination of a collapsing EBIT margin and a reduction in asset turnover. The increase in tax efficiency was insufficient to counteract the sharp decline in operating profitability observed in 2020 and 2021.

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Disaggregation of Net Profit Margin

Biogen Inc., decomposition of net profit margin ratio

Microsoft Excel
Net Profit Margin = Tax Burden × Interest Burden × EBIT Margin
Dec 31, 2021 14.17% = 0.97 × 0.86 × 16.96%
Dec 31, 2020 29.76% = 0.80 × 0.96 × 38.79%
Dec 31, 2019 40.96% = 0.84 × 0.97 × 50.31%
Dec 31, 2018 32.93% = 0.76 × 0.97 × 45.02%
Dec 31, 2017 20.69% = 0.51 × 0.95 × 42.76%

Based on: 10-K (reporting date: 2021-12-31), 10-K (reporting date: 2020-12-31), 10-K (reporting date: 2019-12-31), 10-K (reporting date: 2018-12-31), 10-K (reporting date: 2017-12-31).


The Net Profit Margin exhibited a trajectory of growth followed by a significant contraction over the five-year period. Profitability peaked in 2019 at 40.96% before declining sharply to 14.17% by December 31, 2021. This overall trend was primarily driven by fluctuations in operational efficiency, while tax and interest components played secondary but distinct roles.

EBIT Margin
Operational profitability showed a strong upward trend in the first three years, rising from 42.76% in 2017 to a peak of 50.31% in 2019. However, this was followed by a severe decline, dropping to 38.79% in 2020 and collapsing to 16.96% in 2021. The precipitous drop in the final year indicates a substantial increase in operating expenses or a significant reduction in core revenue efficiency, serving as the primary driver for the erosion of the Net Profit Margin.
Tax Burden
The tax burden ratio improved consistently from 0.51 in 2017 to 0.97 in 2021. This increase suggests that taxes consumed a smaller proportion of pre-tax income over time. The improvement in tax efficiency acted as a partial buffer, mitigating some of the negative impact caused by the declining EBIT margin in the later years.
Interest Burden
Financial expenses remained relatively stable and negligible for the majority of the period, with the interest burden ratio fluctuating narrowly between 0.95 and 0.97 from 2017 to 2020. A notable shift occurred in 2021, where the ratio decreased to 0.86, indicating that interest expenses began to exert a greater downward pressure on the net profit margin relative to the operating income.

In summary, the disaggregation of the Net Profit Margin reveals that while tax efficiencies improved and interest costs remained largely stable until 2021, these factors were insufficient to offset the drastic deterioration in the EBIT margin during the final two years of the analysis.

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